scholarly journals The Synthesis, Characterization and Applications of Polyhydroxyalkanoates (PHAs) and PHA-Based Nanoparticles

Polymers ◽  
2021 ◽  
Vol 13 (19) ◽  
pp. 3302
Author(s):  
Antony V. Samrot ◽  
Sree K. Samanvitha ◽  
N. Shobana ◽  
Emilin R. Renitta ◽  
Puvanesvaran Senthil Kumar ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Fatty Acid ◽  
Zeta Potential ◽  
Hydroxy Fatty Acid ◽  
Biomedical Applications ◽  
Physicochemical Characteristics ◽  
Production Methods ◽  
Solvent Diffusion ◽  
Storage Granules

Polyhydroxyalkanoates (PHAs) are storage granules found in bacteria that are essentially hydroxy fatty acid polyesters. PHA molecules appear in variety of structures, and amongst all types of PHAs, polyhydroxybutyrate (PHB) is used in versatile fields as it is a biodegradable, biocompatible, and ecologically safe thermoplastic. The unique physicochemical characteristics of these PHAs have made them applicable in nanotechnology, tissue engineering, and other biomedical applications. In this review, the optimization, extraction, and characterization of PHAs are described. Their production and application in nanotechnology are also portrayed in this review, and the precise and various production methods of PHA-based nanoparticles, such as emulsion solvent diffusion, nanoprecipitation, and dialysis are discussed. The characterization techniques such as UV-Vis, FTIR, SEM, Zeta Potential, and XRD are also elaborated.

scholarly journals Characterization of endotoxin and 3-hydroxy fatty acid levels in air and settled dust from commercial aircraft cabins

Indoor Air ◽  
2003 ◽  
Vol 13 (2) ◽  
pp. 166-173 ◽  
Author(s):  
C. J. Hines ◽  
M. A. Waters ◽  
L. Larsson ◽  
M. R. Petersen ◽  
A. Saraf ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Hydroxy Fatty Acid ◽  
Commercial Aircraft ◽  
Aircraft Cabins ◽  
Settled Dust

scholarly journals Marine Polysaccharides in Pharmaceutical Applications: Fucoidan and Chitosan as Key Players in the Drug Delivery Match Field

Marine Drugs ◽  
2019 ◽  
Vol 17 (12) ◽  
pp. 654 ◽  
Author(s):  
Ana Isabel Barbosa ◽  
Ana Joyce Coutinho ◽  
Sofia A. Costa Lima ◽  
Salette Reis
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Biomedical Applications ◽  
Chemical Structure ◽  
Final Section ◽  
Biological Properties ◽  
Production Methods ◽  
Bioactive Properties ◽  
Wide Range ◽  
Per Se

The use of marine-origin polysaccharides has increased in recent research because they are abundant, cheap, biocompatible, and biodegradable. These features motivate their application in nanotechnology as drug delivery systems; in tissue engineering, cancer therapy, or wound dressing; in biosensors; and even water treatment. Given the physicochemical and bioactive properties of fucoidan and chitosan, a wide range of nanostructures has been developed with these polysaccharides per se and in combination. This review provides an outline of these marine polysaccharides, including their sources, chemical structure, biological properties, and nanomedicine applications; their combination as nanoparticles with descriptions of the most commonly used production methods; and their physicochemical and biological properties applied to the design of nanoparticles to deliver several classes of compounds. A final section gives a brief overview of some biomedical applications of fucoidan and chitosan for tissue engineering and wound healing.

scholarly journals Review on the Impact of Polyols on the Properties of Bio-Based Polyesters

Polymers ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 2969
Author(s):  
Kening Lang ◽  
Regina J. Sánchez-Leija ◽  
Richard A. Gross ◽  
Robert J. Linhardt
Keyword(s):  
Tissue Engineering ◽  
Biomedical Applications ◽  
Molecular Level ◽  
Potential Utility ◽  
Reaction Conditions ◽  
Wide Range ◽  
Soft Tissue Engineering ◽  
The Impact ◽  
Optimal Reaction

Bio-based polyol polyesters are biodegradable elastomers having potential utility in soft tissue engineering. This class of polymers can serve a wide range of biomedical applications. Materials based on these polymers are inherently susceptible to degradation during the period of implantation. Factors that influence the physicochemical properties of polyol polyesters might be useful in achieving a balance between durability and biodegradability. The characterization of these polyol polyesters, together with recent comparative studies involving creative synthesis, mechanical testing, and degradation, have revealed many of their molecular-level differences. The impact of the polyol component on the properties of these bio-based polyesters and the optimal reaction conditions for their synthesis are only now beginning to be resolved. This review describes our current understanding of polyol polyester structural properties as well as a discussion of the more commonly used polyol monomers.

scholarly journals Physicochemical characterization of the pulp oil of bacuri Attalea phalerata Mart. ex Spreng. (Arecaceae)

2020 ◽  
Vol 21 (3) ◽  
pp. 1-11
Author(s):  
Michelle Cardoso Coimbra ◽  
Débora Maria Moreno Luzia ◽  
Neuza Jorge
Keyword(s):  
Fatty Acids ◽  
Gas Chromatography ◽  
Refractive Index ◽  
Fatty Acid ◽  
Potassium Hydroxide ◽  
High Performance ◽  
Physicochemical Characterization ◽  
Physicochemical Characteristics ◽  
Total Phenolic

The aim of the study was to characterize the pulp oil of bacuri Attalea phalerata Mart. ex Spreng. (Arecaceae) according to official analytical methods. Total phenolic and carotenoids contents were evaluated by spectrophotometry, and tocopherols composition by high-performance liquid chromatography. The fatty acid profile was obtained through gas chromatography from samples transesterified with potassium hydroxide in methanol and n-hexane. According to the proximate composition, bacuri pulp contained 41.5 % carbohydrates and 39.2 % lipids. Regarding its physicochemical properties, the oil showed a free fatty acids content of 0.7 %, a peroxide value of 1.4 meq/kg, a refractive index of 1.463, an iodine number of 84.3 g I2/100 g, a saponification number of 193.5 mg KOH/g, an unsaponifiable matter of 0.5 %, and 48.7 h of oxidative stability. Total phenolic, carotenoids, and tocopherols contents recorded values of 2.4 mg GAE/g, 243.0 µg/g, and 86.8 mg/kg, respectively. The bacuri oil showed a fatty acid composition similar to olive oil and a high percentage of unsaturation, finding 67.3 % of monounsaturated acids, and 11.3 % of polyunsaturated acids. The main fatty acids were oleic (67.3 %), palmitic (13.3 %), and linoleic (10.5 %). Due to its physicochemical characteristics, bacuri oil has a great potential to be used in food preparations, such as salad oil or in margarine formulation.

Characterization of the hydroxy fatty acid content ofBasidiomycotina

1999 ◽  
Vol 44 (6) ◽  
pp. 635-641 ◽  
Author(s):  
T. Řezanka ◽  
O. A. Rozentsvet ◽  
V. M. Dembitsky
Keyword(s):  
Fatty Acid ◽  
Acid Content ◽  
Hydroxy Fatty Acid ◽  
Fatty Acid Content

scholarly journals SYNTHESIS AND CHARACTERIZATION OF COMPOSITES BASED ON HYDROXYAPATITE NANOPARTICLES AND CHITOSAN EXTRACTED FROM SHELLS OF THE FRESHWATER CRAB Potamon algeriense

2020 ◽  
Vol XXV ◽  
pp. 132-142
Author(s):  
Mohammed Lakrat ◽  
Soufiane Fadlaoui ◽  
Mohamed Aaddouz ◽  
Ouahid El Asri ◽  
Mohammed Melhaoui ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Biomedical Applications ◽  
Freshwater Crab ◽  
Hydroxyapatite Nanoparticles ◽  
X Ray Diffraction ◽  
X Ray ◽  
Nanocrystalline Hydroxyapatite

Nanocrystalline hydroxyapatite (n-HAp), which has low crystallinity, has attracted great attention due to its similarity to the inorganic part of human bone. Therefore, many studies have focused on creating new formulations combining n-HAp with some biopolymers, such as chitosan, in order to imitate biological bone tissue. The importance of chitosan and its derivatives in biomedical applications has grown significantly in the last three decades due to its biodegradability and renewable source. Besides, chitosan and its derivatives present excellent biocompatibility and biofunctionality, which make them promising materials in bone tissue engineering. In the present study, the chitosan was, first, extracted from the shell of the freshwater crab species Potamon algeriense following demineralization, deproteinization, decolouration (raw chitin) and deacetylation (chitosan) steps. Then, a novel composite based on n-HAp and extracted chitosan (CTS) with varying chitosan contents, from 5% to 20% (w/w), was synthesized and characterized for potential application in tissue regeneration. The obtained composites were characterized using X-ray diffraction, Fourier transform infrared spectroscopy and thermogravimetric analysis. The precipitated n-HAp/CTS nanocomposites similar to natural bone are promising composites for bone tissue engineering applications.

Biological materials and molecular biomimetics – filling up the empty soft materials space for tissue engineering applications

2015 ◽  
Vol 3 (1) ◽  
pp. 13-24 ◽  
Author(s):  
Ali Miserez ◽  
James C. Weaver ◽  
Ovijit Chaudhuri
Keyword(s):  
Tissue Engineering ◽  
Biomedical Applications ◽  
Genetic Characterization ◽  
Molecular Genetic ◽  
Soft Materials ◽  
Biological Materials ◽  
Molecular Biomimetics ◽  
Materials Used ◽  
Molecular Genetic Characterization

The discovery and molecular (genetic) characterization of novel biological materials offers great potential to expand the range of soft materials used for biomedical applications.

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