scholarly journals Dense and Proximate Development—Daylight in the Downtown Area of a Compact City

2022 ◽  
Vol 14 (2) ◽  
pp. 774
Author(s):  
Elzbieta Rynska ◽  
Maryia Yanchuk
Keyword(s):  
Energy Efficiency ◽  
Critical Factor ◽  
Point Of View ◽  
Lighting System ◽  
Compact City ◽  
University Of Technology ◽  
Starting Point ◽  
Electrical Engineers ◽  
City District ◽  
User Expectations

Daylight is of utmost importance and should be the main source of light in most areas dedicated to working and living. When considering our contemporary way of living, it can be easily discerned that most of our life is spent indoors, yet in a typical architectonic design approach, daylight is too often hardly of consequence. Hence daylight becomes a critical factor. Designers comply with the legal requirements of the solar hours required for areas subjected to constant use. Simultaneously for electrical engineers’ daylight is only an additional source of light valued only where energy efficiency is concerned. The basic idea of this research is to, starting from the concept level, design the building’s volume in line with energy efficiency requirements and user expectations using daylight access strategy as the main parameter. This scope of research has been a subject of various scientific theses conducted within the last years at the Faculty of Architecture Warsaw University of Technology. This paper is dedicated to the latest and most developed outcomes. The presented solution is an architectonic point of view dedicated to the use of the daylight factor in office areas located in a dense city district that may support efficient energy requirements, including the requirements of the electric lighting system. Illumination values were set according to the BREEAM daylight and PN-EN 17037 Daylight of Buildings standard. The presented strategy is unconventional for Poland, but has the potential to be included in practice and should be developed further, together with electrical engineers, as a part of energy-saving solutions. Possibly, it should be followed simultaneously with the development of the compact cities ideas. It is hoped that it might be a starting point for discussion, and for a more detailed interdisciplinary research in the future.

Perspectives and Regulation of the Russian Market for Project-based Transactions under the Kyoto Protocol

2008 ◽  
pp. 108-125
Author(s):  
K. Zavodov
Keyword(s):  
Energy Efficiency ◽  
Market Mechanism ◽  
Point Of View ◽  
Market Regulation ◽  
Foreign Investments ◽  
Russian Market ◽  
Increase Energy Efficiency ◽  
New Form ◽  
Contract Structure ◽  
Carbon Fund

Project-based transactions (PBTs) are a market mechanism of attracting foreign investments in order to abate greenhouse gas emissions and increase energy efficiency of the country’s enterprises. The article provides a classification and analyzes advantages and drawbacks of PBTs from the point of view of a host country. The main trends and factors determining the dynamics of the PBT market are described. Given that Russia currently lags behind the leaders of the PBT market, an incorporation of a state carbon fund is put forward with an aim of channelling PBTs through it. This paper proposes a form of PBT market regulation by incorporating an option mechanism into the contract structure of a transaction. A comparison of the new form of regulation with the tools that are currently in use in Russia and other countries demonstrates its greater economic efficiency under uncertainty.

LES AXES DE LA CRÉATION ET LA NAISSANCE DE LʹIMAGINAIRE COMME LANGAGE MYTHIQUE

Trictrac ◽  
2016 ◽  
Vol 9 ◽  
Author(s):  
Liliana Danciu ◽  
Petru Adrian Danciu
Keyword(s):  
Sacred Space ◽  
Physical World ◽  
Spoken Word ◽  
Point Of View ◽  
Philosophical Approach ◽  
Starting Point ◽  
Written Form ◽  
The Creation ◽  
Religious Systems ◽  
Rich Spectrum

The axes of the creation and birth of the imaginary as a mythical language. Our research follows the relationships of the concepts that are taking into account creation on the double axis of verticality and horizontality. We highlight those symbolic elements which would later constitute the mythical language about the sacred space-temporality. Inside this space-temporality a rich spectrum of mythical images develops; images capable of explaining the relationships of the creation plans. Without a religious perception of the temporality, the conceptualization of the axis would remain a philosophical approach. Through our point of view, the two are born simultaneously. Thanks to them, creation can be imagined. The first “frozen” formula of the mystical human spirit can be thought, brought to a palpable reality, expressed in an oral and then a written form. Studied together, temporality (sacred or not) and space are permanently imagined together. For example, a loss of mundane temporality in the secret ecstasy that offers to the soul an ascending direction does not mean getting out of universal temporality, but of its mundane section. In the sacred space the soul relates to time. Even the gods are submitted by the sacred, Aeon sometimes being synonymous to destiny. The universal creator seems to evade every touch, but not consistently, only when he avoids the descent into its created worlds. In sacredness, time and space seem or become confused, both expressing the same reality, by the immediate swing from thinking to deed. The mythical imagery conceives the displacement in the primary space-temporality by the spoken word. So, for something to appear and live, the spoken word is required. Even the divine dream appears as a pre-word of a creator’s thought. The thought follows the spoken word, the spoken word follows the gestures which finally indicate the meanings of the creative act, controlling the rhythm of the creation days. These three will later be adapted through imitation in rite. We are now situated at the limit of the physical world, a real challenge for the mythical imagery. The general feature of the mythical expression on the creation of the material world is the state of the divinity’s exhaustion, most often conceptualized by sacrifice or divine fatigue. The world geography identifies with the anatomy of a self-gutted god. Practically, material creation is most likely the complete revelation of God’s body autopsy. As each body decomposes, everything in it is an illusion. An axial approach of the phenomenon exists in all religious systems. The created element’s origin is exterior, with or without a pre-existing matter, by a god’s sacrifice or only because it has to be that way. This is the starting point of the discussion on the symbolism of axiality as a reason for the constitution of the language of creation, capable of retelling the imaginary construction of myth in an oral and then written form.

L’absence chez Michel Butor. L’Emploi du temps et Degrés

2012 ◽  
pp. 66-80
Author(s):  
Michał Mrozowicki
Keyword(s):  
Human Memory ◽  
Point Of View ◽  
Narrative Discourse ◽  
The Novel ◽  
Michel Butor ◽  
Starting Point ◽  
One Year ◽  
The Moment ◽  
Narrative Mode ◽  
The City

Michel Butor, born in 1926, one of the leaders of the French New Novel movement, has written only four novels between 1954 and 1960. The most famous of them is La Modification (Second thoughts), published in 1957. The author of the paper analyzes two other Butor’s novels: L’Emploi du temps (Passing time) – 1956, and Degrés (Degrees) – 1960. The theme of absence is crucial in both of them. In the former, the novel, presented as the diary of Jacques Revel, a young Frenchman spending a year in Bleston (a fictitious English city vaguely similar to Manchester), describes the narrator’s struggle to survive in a double – spatial and temporal – labyrinth. The first of them, formed by Bleston’s streets, squares and parks, is symbolized by the City plan. During his one year sojourn in the city, using its plan, Revel learns patiently how to move in its different districts, and in its strange labyrinth – strange because devoid any centre – that at the end stops annoying him. The other, the temporal one, symbolized by the diary itself, the labyrinth of the human memory, discovered by the narrator rather lately, somewhere in the middle of the year passed in Bleston, becomes, by contrast, more and more dense and complex, which is reflected by an increasinly complex narration used to describe the past. However, at the moment Revel is leaving the city, he is still unable to recall and to describe the events of the 29th of February 1952. This gap, this absence, symbolizes his defeat as the narrator, and, in the same time, the human memory’s limits. In Degrees temporal and spatial structures are also very important. This time round, however, the problems of the narration itself, become predominant. Considered from this point of view, the novel announces Gerard Genette’s work Narrative Discourse and his theoretical discussion of two narratological categories: narrative voice and narrative mode. Having transgressed his narrative competences, Pierre Vernier, the narrator of the first and the second parts of the novel, who, taking as a starting point, a complete account of one hour at school, tries to describe the whole world and various aspects of the human civilization for the benefit of his nephew, Pierre Eller, must fail and disappear, as the narrator, from the third part, which is narrated by another narrator, less audacious and more credible.

OWNERSHIP IN THE REPUBLIC OF MACEDONIA AND THE STATE AS THE HOLDER OF THE PROPERTY RIGHT UNDER THE CONSTITUTION IN 1991

2018 ◽  
Vol 28 (6) ◽  
pp. 1993-2005
Author(s):  
Shemsije Demiri ◽  
Rudina Kaja
Keyword(s):  
Legal Aspect ◽  
State Ownership ◽  
The State ◽  
Point Of View ◽  
State Function ◽  
Dominant Form ◽  
Republic Of Macedonia ◽  
General Terms ◽  
Starting Point ◽  
The Republic

This paper deals with the right to property in general terms from its source in Roman law, which is the starting point for all subsequent legal systems. As a result of this, the acquisition of property rights is handled from the historical point of view, with the inclusion of various local and international literature and studies, as well as the legal aspect devoted to the respective civil codes of the states cited in the paper.Due to such socio-economic developments, state ownership and its ownership function have changed. The state function as owner of property also changed in Macedonia's property law.The new constitutional sequence of the Republic of Macedonia since 1991 became privately owned as a dominant form of ownership, however, state ownership also exists.This process of transforming social property into state or private (dissolves), in Macedonia starts from Yugoslavia through privatization, return and denationalization measures, on which basis laws on privatization have been adopted. Because of this, there will be particularly intensive negotiations regaring the remaining state assets.

Enzyme Promiscuous Activity: How to Define it and its Evolutionary Aspects

2020 ◽  
Vol 27 (5) ◽  
pp. 400-410
Author(s):  
Valentina De Luca ◽  
Luigi Mandrich
Keyword(s):  
Gene Evolution ◽  
Sequence Divergence ◽  
High Specificity ◽  
Industrial Applications ◽  
Point Of View ◽  
Enzyme Promiscuity ◽  
Primary Activity ◽  
Starting Point ◽  
Main Activity

: Enzymes are among the most studied biological molecules because better understanding enzymes structure and activity will shed more light on their biological processes and regulation; from a biotechnological point of view there are many examples of enzymes used with the aim to obtain new products and/or to make industrial processes less invasive towards the environment. Enzymes are known for their high specificity in the recognition of a substrate but considering the particular features of an increasing number of enzymes this is not completely true, in fact, many enzymes are active on different substrates: this ability is called enzyme promiscuity. Usually, promiscuous activities have significantly lower kinetic parameters than to that of primary activity, but they have a crucial role in gene evolution. It is accepted that gene duplication followed by sequence divergence is considered a key evolutionary mechanism to generate new enzyme functions. In this way, promiscuous activities are the starting point to increase a secondary activity in the main activity and then get a new enzyme. The primary activity can be lost or reduced to a promiscuous activity. In this review we describe the differences between substrate and enzyme promiscuity, and its rule in gene evolution. From a practical point of view the knowledge of promiscuity can facilitate the in vitro progress of proteins engineering, both for biomedical and industrial applications. In particular, we report cases regarding esterases, phosphotriesterases and cytochrome P450.

Design of Inhibitors for Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) Enzyme of Leishmania mexicana

2020 ◽  
Vol 16 (6) ◽  
pp. 784-795
Author(s):  
Krisnna M.A. Alves ◽  
Fábio José Bonfim Cardoso ◽  
Kathia M. Honorio ◽  
Fábio A. de Molfetta
Keyword(s):  
Molecular Dynamics ◽  
Molecular Dynamics Simulations ◽  
Binding Site ◽  
Point Of View ◽  
New Drugs ◽  
Leishmania Mexicana ◽  
Receptor Complexes ◽  
Starting Point ◽  
Dynamics Simulations ◽  
Selection Of

Background:: Leishmaniosis is a neglected tropical disease and glyceraldehyde 3- phosphate dehydrogenase (GAPDH) is a key enzyme in the design of new drugs to fight this disease. Objective:: The present study aimed to evaluate potential inhibitors of GAPDH enzyme found in Leishmania mexicana (L. mexicana). Methods: A search for novel antileishmanial molecules was carried out based on similarities from the pharmacophoric point of view related to the binding site of the crystallographic enzyme using the ZINCPharmer server. The molecules selected in this screening were subjected to molecular docking and molecular dynamics simulations. Results:: Consensual analysis of the docking energy values was performed, resulting in the selection of ten compounds. These ligand-receptor complexes were visually inspected in order to analyze the main interactions and subjected to toxicophoric evaluation, culminating in the selection of three compounds, which were subsequently submitted to molecular dynamics simulations. The docking results showed that the selected compounds interacted with GAPDH from L. mexicana, especially by hydrogen bonds with Cys166, Arg249, His194, Thr167, and Thr226. From the results obtained from molecular dynamics, it was observed that one of the loop regions, corresponding to the residues 195-222, can be related to the fitting of the substrate at the binding site, assisting in the positioning and the molecular recognition via residues responsible for the catalytic activity. Conclusion:: he use of molecular modeling techniques enabled the identification of promising compounds as inhibitors of the GAPDH enzyme from L. mexicana, and the results obtained here can serve as a starting point to design new and more effective compounds than those currently available.

scholarly journals New Housing Developments in the City Center of Guadalajara (Mexico): An Analysis from the Perspective of Collective and Sustainable Dwelling

Buildings ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 168
Author(s):  
Alessandra Cireddu
Keyword(s):  
Point Of View ◽  
City Center ◽  
Compact City ◽  
Housing Developments ◽  
Human Scale ◽  
Horizontal Growth ◽  
Downtown Redevelopment ◽  
Mode Of Transport ◽  
The City ◽  
New Buildings

New vertical housing developments in Guadalajara (Mexico) are reaching the city center as a response for redensification after many years of expansion of the urban area characterized by a suburban, low density and fragmented pattern. This horizontal growth, dominated by use of the automobile as prevailing mode of transport, has proven to be unsustainable not only from an environmental point of view, but also from a social perspective where the “human scale” of the city has been affected, same as the daily life of its inhabitants. On the other hand, vertical housing proposals are by their very nature associated with concepts of redensification, compact city and collective living; the aim of this article is to analyze some new housing developments in Guadalajara downtown in order to evaluate to what extent the new buildings embody a more sustainable, livable and collective dwelling, to discuss findings, successes and failures and thus be able to contribute some conclusions and open a broader reflection about contemporary housing, urban density and downtown redevelopment in Latin America cities through collective and sustainable dwelling.

Changes in the Prognosis of Functional Psychoses Since the Days of Kraepelin

1967 ◽  
Vol 113 (501) ◽  
pp. 813-822 ◽  
Author(s):  
Örnulv Ödegård
Keyword(s):  
Special Problem ◽  
Point Of View ◽  
General Point ◽  
Course Of Illness ◽  
Dynamic Reasoning ◽  
Starting Point ◽  
Functional Psychoses ◽  
External Conditions ◽  
Point Of Departure ◽  
The Universe

My choice of Kraepelin as a point of departure for this lecture has definite reasons. If one wants to stay within the field of clinical psychiatry (as opposed to psychiatric history), that is as far back as one can reasonably go. By this no slight is intended upon the pre-Kraepelinian psychiatrists. For our topic Henry Maudsley would indeed have been a most appropriate starting point, and by no means for reasons of courtesy. His general point of view is admirably sound as a basis for the scientific study of prognosis in psychiatry. I quote: “There is no accident in madness. Causality, not casualty, governs its appearance in the universe, and it is very far from being a good and sufficient practice simply to mark its phenomena and straightway to pass on as if they belonged not to an order but to a disorder of events that called for no explanation.” On the special problem of prognosis he shows his clinical acumen by stating that the outlook is poor when the course of illness is insidious, but this only means that these cases develop their psychoses on the basis of mental deviations which go very far back in the patient's life, so that in fact they are generally in a chronic stage at the time of their first admission to hospital. Here he actually corrects a mistake which is still quite often made. He shows his dynamic attitude when he says that prognosis is to a large extent modified by external conditions, in particular by the attitude of friends and relatives. Maudsley's dynamic reasoning was limited by the narrow framework of the degeneration hypothesis of those days. He had a sceptical attitude towards classification, which he regarded as artificial and dangerously pseudo-exact. His own classification was deliberately provisional, with very wide groups. He held that a description of various sub-forms of chronic insanity was useless, as it would mean nothing but a tiresome enumeration of unconnected details.

Energieeffizienz beim Spanen/Energy efficiency at machining - Investigations about the influence of minimun quantity lubrication (MQL) at final cutting

2017 ◽  
Vol 107 (05) ◽  
pp. 352-358
Author(s):  
S. Prof. Simon ◽  
S. Wichmann ◽  
A. Brill
Keyword(s):  
Energy Efficiency ◽  
Minimum Quantity Lubrication ◽  
Stress Conditions ◽  
Cutting Performance ◽  
Workpiece Material ◽  
Load Range ◽  
University Of Technology ◽  
Partial Load ◽  
Longitudinal Turning

Von der Brandenburgischen Technischen Universität (BTU) sind in Zusammenarbeit mit der TU Liberec Untersuchungen zur Verbesserung der Energieeffizienz an spanenden Werkzeugmaschinen durchgeführt worden. Im Gegensatz zu bereits durchgeführten Untersuchungen wurde der Fokus hier auf das Belastungsverhalten im Teillastbereich gerichtet. Die durchgeführten Untersuchungen beschränkten sich auf das Längsdrehen mit geringen Schnitttiefen. Als Werkstoffe kamen ein Baustahl und ein Vergütungsstahl zum Einsatz. Durch die Bestimmung der Leerlaufleistung der verwendeten Drehmaschine waren tatsächliche Aussagen über die Schnittleistung möglich. Für das Ermitteln des Wirkungsgrades wurden auch die Schnittleistungen bei verschiedenen Drehzahlen aufgenommen. Alle weiteren Spanungsbedingungen blieben für die Untersuchungen konstant. Im Ergebnis der Untersuchung bestätigte sich das Potenzial der Minimalmengenschmierung. Der Wirkungsgrad verbesserte sich durchschnittlich um 5 %. Beachtenswert ist der Einfluss des Einstellwinkels. Hier liegt das Optimierungspotenzial der Energieeffizienz in Summe bei 14 %. Die Untersuchungen ergaben weiterhin eine hohe Korrelation von Spanungsbedingungen, Werkstückwerkstoff und verwendetem Schmiermittel.   The Brandenburg University of Technology has carried out investigations in cooperation with the technical University of Liberec to improve the energy efficiency of cutting machine tools. In contrast to investigations already carried out, the focus here was on the loading behavior in the partial load range. The investigations carried out were limited to longitudinal turning with low cutting depths. A structural steel and a tempering steel were used as materials. By determining the no-load power of the used lathe, actual statements about the cutting performance were possible. For the determination of the efficiency, the cutting performance was recorded at different speeds. All further stress conditions remained constant for the investigations. As a result of the investigation, the potential of minimum quantity lubrication was confirmed. The efficiency improved by an average of 5 %. The influence of the angle of setting was remarkable. The optimization potential of energy efficiency was at 14 %. The investigations also revealed a high correlation between stress conditions, workpiece material and lubricant used.

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