Modern aspects of diagnosis and treatment of intestinal dysbiosis in the practice of a paramedic

2021 ◽  
pp. 70-74
Author(s):  
Vsevolod Vladimirovich Skvortsov
Keyword(s):  
Diagnosis And Treatment ◽  
Physician Practice ◽  
Intestinal Dysbiosis ◽  
New Generation

This article focuses on the use of a new generation of drugs to eliminate and prevent dysbiosis in physician practice.

Recent Advances of Silver Nanoparticles in Cancer Diagnosis and Treatment

2020 ◽  
Vol 20 (11) ◽  
pp. 1276-1287 ◽  
Author(s):  
Tran Q. Huy ◽  
Pham T.M. Huyen ◽  
Anh-Tuan Le ◽  
Matteo Tonezzer
Keyword(s):  
Silver Nanoparticles ◽  
Cancer Treatment ◽  
Cancer Diagnosis ◽  
Essential Role ◽  
Review Paper ◽  
Diagnosis And Treatment ◽  
Antimicrobial Material ◽  
Pathogenic Agents ◽  
New Generation ◽  
Carrier Systems

Background: Silver nanoparticles (AgNPs) are well-known as a promising antimicrobial material; they have been widely used in many commercial products against pathogenic agents. Despite a growing concern regarding the cytotoxicity, AgNPs still have attracted considerable interest worldwide to develop a new generation of diagnostic tool and effective treatment solution for cancer cells. Objective: This paper aims to review the advances of AgNPs applied for cancer diagnosis and treatment. Methods: The database has been collected, screened and analysed through up-to-date scientific articles published from 2007 to May 2019 in peer-reviewed international journals. Results: The findings of the database have been analysed and divided into three parts of the text that deal with AgNPs in cancer diagnosis, their cytotoxicity, and the role as carrier systems for cancer treatment. Thanks to their optical properties, high conductivity and small size, AgNPs have been demonstrated to play an essential role in enhancing signals and sensitivity in various biosensing platforms. Furthermore, AgNPs also can be used directly or developed as a drug delivery system for cancer treatment. Conclusion: The review paper will help readers understand more clearly and systematically the role and advances of AgNPs in cancer diagnosis and treatment.

scholarly journals Ultrasound-mediated delivery of RGD-conjugated nanobubbles loaded with fingolimod and superparamagnetic iron oxide nanoparticles: targeting hepatocellular carcinoma and enhancing magnetic resonance imaging

RSC Advances ◽  
2020 ◽  
Vol 10 (64) ◽  
pp. 39348-39358
Author(s):  
Xin-Min Guo ◽  
Jia-Lin Chen ◽  
Bao-Hui Zeng ◽  
Ji-Chuang Lai ◽  
Cui-Yan Lin ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Hepatocellular Carcinoma ◽  
Iron Oxide ◽  
Magnetic Resonance ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Diagnosis And Treatment ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
New Generation

Nanobubbles (NBs) are considered to be a new generation of ultrasound-responsive nanocarriers that can effectively target tumors, accurately release multi-drugs at desired locations, as well as simultaneously perform diagnosis and treatment.

scholarly journals Recent Trends in Biomedical Applications of Nanomaterials

2018 ◽  
Vol 15 (2) ◽  
pp. 235-243 ◽  
Author(s):  
Khalid E. Ibrahim ◽  
Amel O. Bakhiet ◽  
Ayaat Khan ◽  
Haseeb A. Khan
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Biomedical Applications ◽  
Disease Diagnosis ◽  
Diagnosis And Treatment ◽  
Biomedical Sciences ◽  
Design And Synthesis ◽  
Recent Trends ◽  
Targeted Drug ◽  
New Generation

In recent years, there have been enormous developments in utilizing the potential of nanotechnology in different fields including biomedical sciences. The most remarkable biomedical applications of nanoparticles (NPs) are in the diagnosis and treatment of various diseases. Functionalization of NPs renders them unique properties so that they can be used as contrast agent for dual or triple modal imaging. The design and synthesis of new generation NPs aiming at targeted drug delivery has revolutionized the safe and effective therapies for complex and difficult to treat diseases. The theranostic NPs possess the dual capabilities for disease diagnosis and treatment. This review highlights the biomedical applications of NPs based on recent reports published in this area of research.

scholarly journals Intestinal dysbiosis is a risk factor or a cause of miscarriage?

2018 ◽  
Vol 67 (2) ◽  
pp. 70-78 ◽  
Author(s):  
Alexandr A. Bezmenko ◽  
Natalya D. Kislitsyna
Keyword(s):  
Risk Factor ◽  
Gastrointestinal Tract ◽  
Chromosomal Abnormalities ◽  
Diagnosis And Treatment ◽  
Spontaneous Abortions ◽  
New Methods ◽  
Intestinal Dysbiosis ◽  
Reproductive Losses

The number of spontaneous abortions continues to increase despite the new methods of diagnosis and treatment. A total of 15%–23% of confirmed pregnancies end in spontaneous miscarriages. Of the causes of reproductive losses, approximately 7% are chromosomal abnormalities, and the remaining are conditionally preventable. This article discusses the role of intestinal dysbiosis in the pathogenesis of miscarriage. Focus on this issue and the evaluation of the effectiveness of the treatment of gastrointestinal tract diseases may be a primary way to prevent early reproductive losses.

METAPEX – A NEW GENERATION OBTURATING MATERIAL??- A CASE REPORT

2021 ◽  
pp. 3-4
Author(s):  
Athul Chandra Manedath ◽  
Sachita Naik ◽  
Madhu Pujar
Keyword(s):  
Case Report ◽  
Success Rate ◽  
Treatment Plan ◽  
Interdisciplinary Approach ◽  
Diagnosis And Treatment ◽  
Present Case Report ◽  
Radiographic Features ◽  
New Generation ◽  
Careful Investigation

The complex interrelationship between the endodontic and periodontal lesion has always lead to controversies, confusion and debate. The pulpal infection can spread and cause a periodontal lesion or vice-versa. Detecting the origin of the infection is crucial. Thus, a careful investigation of the history, symptoms, clinical and radiographic features should be done to reach a denitive diagnosis and treatment plan. An interdisciplinary approach to such cases gives a higher success rate. The present case report deals with the management of an endo-perio lesion with an unforeseen double le separation. The novelness in this case lies in the management of the double le separation in a single canal using metapex.

Application of semiconductor and metal nanostructures in biology and medicine

Hematology ◽  
2009 ◽  
Vol 2009 (1) ◽  
pp. 701-707 ◽  
Author(s):  
Carl Walkey ◽  
Edward A. Sykes ◽  
Warren C. W. Chan
Keyword(s):  
Contrast Agents ◽  
Metallic Nanostructures ◽  
Delivery Systems ◽  
Current Understanding ◽  
Diagnosis And Treatment ◽  
Metal Nanostructures ◽  
Clinical Use ◽  
Nanotechnology Research ◽  
Chemical Design ◽  
New Generation

Abstract Advances in nanotechnology research have led to the creation of new generation of contrast agents, therapeutics, and delivery systems. These applications are expected to significantly improve the diagnosis and treatment of a variety of diseases. Two nanotechnologies—semiconductor and metallic nanostructures—are the most advanced in this young field and have been extensively investigated for clinical use. These nanostructures are currently the “model” for the developments of many novel nanostructures. This review describes their chemical design, tunable properties, and utility in medicine. Furthermore, we will describe the current understanding of their toxicity, which could be barriers to their use for human.

Finding the Right Problems: Some HREM Applications to Interfaces

1984 ◽  
Vol 42 ◽  
pp. 376-379
Author(s):  
D. Cherns
Keyword(s):  
Grain Boundaries ◽  
High Resolution Electron Microscopy ◽  
Boundary Structure ◽  
Atomic Structures ◽  
Grain Boundary Structure ◽  
Resolution Electron ◽  
Point To Point ◽  
The Right ◽  
New Generation ◽  
Better Than

The use of high resolution electron microscopy (HREM) to determine the atomic structure of grain boundaries and interfaces is a topic of great current interest. Grain boundary structure has been considered for many years as central to an understanding of the mechanical and transport properties of materials. Some more recent attention has focussed on the atomic structures of metalsemiconductor interfaces which are believed to control electrical properties of contacts. The atomic structures of interfaces in semiconductor or metal multilayers is an area of growing interest for understanding the unusual electrical or mechanical properties which these new materials possess. However, although the point-to-point resolutions of currently available HREMs, ∼2-3Å, appear sufficient to solve many of these problems, few atomic models of grain boundaries and interfaces have been derived. Moreover, with a new generation of 300-400kV instruments promising resolutions in the 1.6-2.0 Å range, and resolutions better than 1.5Å expected from specialist instruments, it is an appropriate time to consider the usefulness of HREM for interface studies.

Total etch dentin bonding systems: scanning electron microscopy of the resin-dentin hybrid layer

1992 ◽  
Vol 50 (2) ◽  
pp. 1092-1093
Author(s):  
Jorge Perdigao
Keyword(s):  
Composite Resin ◽  
Mechanical Interlocking ◽  
Hybrid Layer ◽  
Agent Based ◽  
Dentin Bonding ◽  
Acid Agent ◽  
Bond Strengths ◽  
Main Component ◽  
Bonding Systems ◽  
New Generation

In 1955, Buonocore introduced the etching of enamel with phosphoric acid. Bonding to enamel was created by mechanical interlocking of resin tags with enamel prisms. Enamel is an inert tissue whose main component is hydroxyapatite (98% by weight). Conversely, dentin is a wet living tissue crossed by tubules containing cellular extensions of the dental pulp. Dentin consists of 18% of organic material, primarily collagen. Several generations of dentin bonding systems (DBS) have been studied in the last 20 years. The dentin bond strengths associated with these DBS have been constantly lower than the enamel bond strengths. Recently, a new generation of DBS has been described. They are applied in three steps: an acid agent on enamel and dentin (total etch technique), two mixed primers and a bonding agent based on a methacrylate resin. They are supposed to bond composite resin to wet dentin through dentin organic component, forming a peculiar blended structure that is part tooth and part resin: the hybrid layer.

Low-voltage, high-resolution scanning electron microscopy of polymers

1987 ◽  
Vol 45 ◽  
pp. 466-467 ◽  
Author(s):  
S. J. Krause ◽  
W.W. Adams ◽  
S. Kumar ◽  
T. Reilly ◽  
T. Suziki
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Low Voltage ◽  
Chromatic Aberration ◽  
Image Resolution ◽  
Resolution Limit ◽  
Crossover Point ◽  
New Generation ◽  
Beam Damage ◽  
Scanning Electron

Scanning electron microscopy (SEM) of polymers at routine operating voltages of 15 to 25 keV can lead to beam damage and sample image distortion due to charging. Imaging polymer samples with low accelerating voltages (0.1 to 2.0 keV), at or near the “crossover point”, can reduce beam damage, eliminate charging, and improve contrast of surface detail. However, at low voltage, beam brightness is reduced and image resolution is degraded due to chromatic aberration. A new generation of instruments has improved brightness at low voltages, but a typical SEM with a tungsten hairpin filament will have a resolution limit of about 100nm at 1keV. Recently, a new field emission gun (FEG) SEM, the Hitachi S900, was introduced with a reported resolution of 0.8nm at 30keV and 5nm at 1keV. In this research we are reporting the results of imaging coated and uncoated polymer samples at accelerating voltages between 1keV and 30keV in a tungsten hairpin SEM and in the Hitachi S900 FEG SEM.

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