Silicon in the fight against opportunistic skin infections (experimental and clinical studies)

2020 ◽  
pp. 7-13
Author(s):  
Sh. Мavlyanova ◽  
P. Mavlyanov ◽  
J. Mullakhanov ◽  
A. Ismogilov
Keyword(s):  
Chemical Composition ◽  
Clinical Studies ◽  
Experimental Studies ◽  
Skin Infections ◽  
Infection Efficiency

The article presents the results of chemical, clinical and experimental studies of siliceous solutions. The results of the study showed that siliceous solutions, due to the chemical composition of medicinal minerals and REE elements, contribute to the enrichment of the chelating protein calprotectin in neutrophils, which further inhibits the growth of mixed bacterial and viral microorganisms, which leads to anti-infection efficiency.

Exneriana – II – The Scientific Legacy of John E. Exner, Jr. 1Part of this paper was presented at the XIXth International Congress of Rorschach and Projective Methods, July 22–26, 2008, Louvain, Belgium.

2008 ◽  
Vol 29 (2) ◽  
pp. 81-107 ◽  
Author(s):  
Anne Andronikof
Keyword(s):  
Clinical Studies ◽  
Experimental Studies ◽  
Scientific Work ◽  
International Congress ◽  
Response Process ◽  
Scientific Legacy ◽  
Projective Test ◽  
Projective Methods ◽  
Comprehensive Picture ◽  
Complex Mechanisms

Based on an analysis of John Exner’s peer-reviewed published work from 1959 to 2007, plus a brief comment for an editorial in Rorschachiana, the author draws a comprehensive picture of the scientific work of this outstanding personality. The article is divided into three sections: (1) the experimental studies on the Rorschach, (2) the clinical studies using the Rorschach, and (3) Exner’s “testament,” which we draw from the last paper he saw published before his death (Exner, 2001/2002). The experimental studies were aimed at better understanding the nature of the test, in particular the respective roles of perception and projection in the response process. These fundamental studies led to a deeper understanding of the complex mechanisms involved in the Rorschach responses and introduced some hypotheses about the intentions of the author of the test. The latter were subsequently confirmed by the preparatory sketches and documents of Hermann Rorschach, which today can be seen at the H. Rorschach Archives and Museum in Bern (Switzerland). Exner’s research has evidenced the notion that the Rorschach is a perceptive-cognitive-projective test.

scholarly journals Toxic Animal-Based Medicinal Materials Can Be Effective in Treating Endometriosis: A Scoping Review

Toxins ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 145
Author(s):  
Su-In Hwang ◽  
Young-Jin Yoon ◽  
Soo-Hyun Sung ◽  
Ki-Tae Ha ◽  
Jang-Kyung Park
Keyword(s):  
Side Effects ◽  
Clinical Studies ◽  
Malignant Tumors ◽  
Experimental Studies ◽  
Herbal Medicines ◽  
Treatment Method ◽  
Reproductive Age ◽  
Dependent Growth ◽  
Gynecological Disorder ◽  
Preclinical And Clinical Studies

Animal toxins and venoms have recently been developed as cancer treatments possessing tumor cell growth-inhibitory, antiangiogenesis, and proapoptotic effects. Endometriosis is a common benign gynecological disorder in reproductive-age women, and no definite treatment for this disorder is without severe side effects. As endometriosis and malignant tumors share similar characteristics (progressive, invasive, estrogen-dependent growth, and recurrence), animal toxins and venoms are thought to be effective against endometriosis. The objective of this study was to outline studies using toxic animal-based medicinal materials (TMM) as endometriosis treatment and to explore its clinical applicability. Preclinical and clinical studies using TMM were searched for in four databases from inception to October 2020. A total of 20 studies of TMM on endometriosis were included. In eight clinical studies, herbal medicines containing TMM were effective in relieving symptoms of endometriosis, with no side effects. In twelve experimental studies, the main therapeutic mechanisms of TMM against endometriosis were proapoptotic, antiangiogenesis, estrogen level-reducing, and possible anti-inflammatory effects. TMM are thus considered promising sources for the development of an effective treatment method for endometriosis. Further studies are needed to clarify the therapeutic mechanism of TMM against endometriosis and to provide sufficient grounds for clinical application.

scholarly journals Influence of different temperature regimes at torrefaction of chicken litter on yield and properties of products

2019 ◽  
Vol 114 ◽  
pp. 06007
Author(s):  
Olga Larina ◽  
Yana Pudova
Keyword(s):  
Chemical Composition ◽  
Thermogravimetric Analysis ◽  
Liquid Fraction ◽  
Experimental Studies ◽  
Calorific Value ◽  
Solid Residue ◽  
Optimum Temperature ◽  
Volume Yield ◽  
Temperature Regimes ◽  
Chicken Litter

The purpose of the research is study the influence of the torrefaction process on the fuel properties of the chicken litter. Experimental studies on lab-scale system at five temperature regimes of torrefaction (220, 240, 260, 280, and 300 °C) with a holding time determined using thermogravimetric analysis were conducted. The products of the torrefaction are solid residue, non-condensable gases, and tar. For the feedstock and torrefied material the elemental composition, the lower calorific value, hygroscopicity limit and bulk density are determined. For liquid fraction the analysis of the chemical composition is carried out. The properties of non-condensable gases as chemical composition and calorific value - are investigated. Mass yields of the solid residue and tar, and specific volume yield of the non-condensable gases are presented. The conclusion about the optimum temperature regime for torrefaction of chicken litter based on the results of experimental studies is made.

scholarly journals Prosopis Plant Chemical Composition and Pharmacological Attributes: Targeting Clinical Studies from Preclinical Evidence

Biomolecules ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. 777 ◽  
Author(s):  
Javad Sharifi-Rad ◽  
Farzad Kobarfard ◽  
Athar Ata ◽  
Seyed Abdulmajid Ayatollahi ◽  
Nafiseh Khosravi-Dehaghi ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Clinical Studies ◽  
Positive Impact ◽  
Biological Effects ◽  
Food Supplement ◽  
In Vivo Studies ◽  
Plant Chemical ◽  
Food Applications

Members of the Prosopis genus are native to America, Africa and Asia, and have long been used in traditional medicine. The Prosopis species most commonly used for medicinal purposes are P. africana, P. alba, P. cineraria, P. farcta, P. glandulosa, P. juliflora, P. nigra, P. ruscifolia and P. spicigera, which are highly effective in asthma, birth/postpartum pains, callouses, conjunctivitis, diabetes, diarrhea, expectorant, fever, flu, lactation, liver infection, malaria, otitis, pains, pediculosis, rheumatism, scabies, skin inflammations, spasm, stomach ache, bladder and pancreas stone removal. Flour, syrup, and beverages from Prosopis pods have also been potentially used for foods and food supplement formulation in many regions of the world. In addition, various in vitro and in vivo studies have revealed interesting antiplasmodial, antipyretic, anti-inflammatory, antimicrobial, anticancer, antidiabetic and wound healing effects. The phytochemical composition of Prosopis plants, namely their content of C-glycosyl flavones (such as schaftoside, isoschaftoside, vicenin II, vitexin and isovitexin) has been increasingly correlated with the observed biological effects. Thus, given the literature reports, Prosopis plants have positive impact on the human diet and general health. In this sense, the present review provides an in-depth overview of the literature data regarding Prosopis plants’ chemical composition, pharmacological and food applications, covering from pre-clinical data to upcoming clinical studies.

scholarly journals Post-operative capsular opacification

1970 ◽  
Vol 1 (1) ◽  
pp. 43-59 ◽  
Author(s):  
SM Raj ◽  
AR Vasavada ◽  
SR Kaid Johar ◽  
VA Vasavada ◽  
VA Vasavada
Keyword(s):  
Clinical Studies ◽  
Experimental Studies ◽  
Surgical Techniques ◽  
Crystalline Lens ◽  
Posterior Capsular Opacification ◽  
Pharmacological Agents ◽  
Low Contrast ◽  
Physiological Consequence ◽  
Culture Models ◽  
Capsular Bag

Post-operative capsular opacification (PCO) is a multifactorial physiological consequence of cataract surgery. Opacification involving the central posterior capsule has a significant impact on high and low contrast acuity and low contrast sensitivity. The assessment of PCO on cadaver eyes, experimental studies and culture models and in clinical studies has provided an understanding of its pathogenesis. The proliferation, migration and abnormal differentiation of residual lens epithelial cells and fibers in the capsular bag have been implicated in the pathogenesis of PCO. The incidence and severity of PCO correlates to the use of surgical techniques, intraocular lens (IOL) optic edge designs and IOL materials. This article summarizes the clinical studies with recommendations for retarding the development of central PCO. It discusses experiments with pharmacological agents broadly categorized as anti-inflammatory, immuno-modulating, antiproliferative, antiadhering and antitransdifferentiating agents for the prevention of PCO. These studies will remain critical for future endeavors undertaken for the eradication of PCO. Key words: posterior capsular opacification; capsular opacification; cataract; crystalline lens; phacoemulsification DOI: 10.3126/nepjoph.v1i1.3673 Nep J Oph 2009;1(1):43-59

Pain processing in Schizophrenia

2011 ◽  
Vol 26 (S2) ◽  
pp. 2130-2130
Author(s):  
O. Bonnot ◽  
S. Tordjman
Keyword(s):  
Clinical Studies ◽  
Pain Sensitivity ◽  
Pain Threshold ◽  
Pain Perception ◽  
Psychiatric Patients ◽  
Case Reports ◽  
Experimental Studies ◽  
Self Report ◽  
Pain Expression ◽  
Endogenous Analgesia

We will propose a critical review of the scientific literature regarding pain and schizophrenia, examine the empirical basis for the reported pain insensitivity of schizophrenia, and emphasize the distinction between behavioral responses to pain or self-reported pain and physiological response to painful stimuli. Litterature is scarse and could be classified in 4 groups: case reports (n = 9), clinical studies (n = 23), experimental research (n = 20) and review articles (n = 5).The analysis of Case reports and clinical studies show reduced pain reactivity in patients with schizophrenia compared to healthy controls or other psychiatric patients. In the same vein, experimental studies using self-report measures of pain reactivity generally reported higher pain perception thresholds in patients with schizophrenia. However, the only experimental study using a neurophysiological measure of pain reactivity (the nociceptive RIII reflex) demonstrated a normal pain threshold in schizophrenia.Review of clinical and experimental data indicates that in most situations behavioral pain reactivity and self-reported responses to pain are reduced in schizophrenia. However, there is little or no physiological evidence supporting pain insensitivity in schizophrenia. It can be suggested that the widely accepted notion of reduced pain sensitivity in schizophrenia is related more to a different mode of pain expression than to a real endogenous analgesia. We will also present preliminary data on pain sensitivity associating behavioural pain reactivity measurements, "objective" electrophysiological assessments and neurovegetative function recordings. Our results are in the line of the literature and strongly suggest that there is no analgesia in schizophrenia but a different mode of pain expression.

scholarly journals MORE ON DEVELOPING FISH PASTE WITH IMPROVED BIOLOGICAL VALUE

2020 ◽  
Vol 2020 (3) ◽  
pp. 134-143
Author(s):  
Maria Evgenievna Tsibizova
Keyword(s):  
Chemical Composition ◽  
Calcium Phosphate ◽  
Grass Carp ◽  
Raw Materials ◽  
Food Additives ◽  
Experimental Studies ◽  
Mineral Supplement ◽  
Mineral Supplements ◽  
Phosphate Mineral ◽  
Physiological Group

In the context of the organization of proper nutrition of the population of Russia, regardless of belonging to any physiological group, taking into account the eating behavior of a modern person, the research has been carried out to expand the range of fish pastes by modifying their recipes. The goal has been achieved by combining raw materials of different origins and reducing the mass fraction of table salt. Experimental studies were carried out to substantiate the recipe compositions of pastes based on grass carp meat, the optimal proportion of calcium-phosphate mineral supplements was defined, a comparative analysis of organoleptic indicators of quality, chemical composition and energy value of the obtained products was conducted. It has been stated that the introduction of 2.5% of phosphate-calcium food additives into paste recipes No. 4 and 5 did not adversely affect the organoleptic quality indicators. The pastes produced according to recipes No. 4 and No. 5, which include grass carp meat (48%), chicken liver (10%), vegetable components (17%), calcium-phosphate mineral supplement (2,5%) and flavoring substances, can be recommended for mass nutrition of the population of Russia. The ratio of these components provides the high organoleptic properties and improved nutritional value. The inclusion of fish pastes enriched with vegetable components, chicken by-products, phosphate-calcium mineral supplements, differing in chemical composition, in the diet allows balancing the diet for proteins, fats, amino acids, vitamins, macro- and micronutrients and preventing from eating disorders and, in the result, reducing morbidity of population in the Russian Federation.

scholarly journals CARBOHYDRATE COUSINIA ANGRENI JUS (ASTERACEAE), ESTABLISHING THE STRUCTURE OF THEIR GLU-COFRUCTANS

2020 ◽  
pp. 41-47
Author(s):  
Kenesh Turdumambetovich Turdumambetov ◽  
Zulayka Sulaimanovna Azhibaeva ◽  
Dzhanymbyu Jorupbekova ◽  
Raisa Andreyevna Goncharova ◽  
Elnura Esenbaevna Ernazarova
Keyword(s):  
Chemical Composition ◽  
Main Product ◽  
Experimental Studies ◽  
13C Nmr Spectroscopy ◽  
Water Soluble ◽  
Special Role ◽  
Plant Materials ◽  
Carbohydrate Complex ◽  
Living Organisms ◽  
Layer Chromatography

Currently, a lot of attention is paid to a number of researchers oligo – and polysaccharides. This is due to their high content in plant materials and the fulfillment of a special role in the development of living organisms, which is of great importance in the production of fructose, sucrose and inulin. Kyrgyzstan has huge reserves of still little-studied, environmentally friendly medicinal and other plant species. The article deals with the study of the chemical composition of the carbohydrate complex in plants of the genus Cousinia angreni Jus. Experimental studies have been carried out to isolate and establish structures of water-soluble polysaccharides and alcohol-soluble oligosaccharides. Glucofructan was isolated from the roots of Cousinia angreni Jus, the structure of individual fractions was studied by methylation, periodic oxidation, paper chromatography, thin-layer chromatography and GLC, IR and 13C-NMR spectroscopy. When compared with witnesses, 2,3,4,6-tetra-O-Me-D-glucose, 1,3,4,6-tetra-O-Me-D-fructose, 3,4,6-tri-O-Me-D-fructose (main product) and trace amounts of 1,3,4-tri-O-Me-D-fructose. The presence of the main product 3,4,6-tri-O-Me-D-fructose indicates the predominance of β-(2→1) bonds. Thus, it was found that glucofructans of the Angren cousin (C. angreni Jus) consist of fructofuranose residues linked by β-(2→1) inulin type bonds.

scholarly journals A Critical Review on Balachaturbhadra Churna: An Effective Ayurveda Formulation for the Pediatric Age

2019 ◽  
Vol 2 (1) ◽  
pp. 1-10
Author(s):  
Abhishek Joshi ◽  
Shrikrishna Rajagopala ◽  
Patel Kalpana S.
Keyword(s):  
Quality Control ◽  
Critical Review ◽  
Clinical Studies ◽  
Experimental Studies ◽  
Therapeutic Use ◽  
Pediatric Age ◽  
Research Papers ◽  
Safety And Efficacy ◽  
Dose Levels ◽  
The Impact

Balachaturbhadra Churna offers a multitude of health benefits for which it has become so poapular prescription by Kaumarbhritya practioners of Ayurveda. It is a combination of four drugs Musta, Pippali, Ativisha and Karkatashringi. This combination was first mentioned in Chakradatta and has been in practice since a millennium. Many queries have been raised on the usage of Aconite species of drugs recently, thus doubting the safety and efficacy of Balachaturbhadra Churna. Very few works have been published on Balachaturbhadra Churna till now. The aim of the present study was to compile and review such available references from classics and research works published on Balachaturbhadra Churna. Total five studies are published on Balachaturbhadra Churna, which revalidated the impact of classical guidelines. The research papers revealed standards of Quality Control and pharmacological efficacy of the drug. All the experimental studies revealed that Balachaturbhadra Churna is having no toxic hazards at very higher Dose levels, proving it safe for therapeutic use. Though certain limitations were observed in these researches, the results can be considered as a lead for further well stratified clinical studies.

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