scholarly journals Assessment and Biomonitoring of the Effect of Rapeseeds Oil on Wister Rat Organs

2019 ◽  
pp. 20-29 ◽  
Keyword(s):  
Weight Loss ◽  
Rural Areas ◽  
Rapeseed Oil ◽  
Control Diet ◽  
The Body ◽  
Dependent Manner ◽  
Efficiency Ratio ◽  
Food Efficiency ◽  
Food Efficiency Ratio ◽  
Group A

Rapeseed oil is one of the important and cheapest vegetable oil in Bangladesh and many other countries. It is commonly used as cooking oil in Bangladesh particularly in rural areas and also used as other food items. This study evaluated the physiological effects of four type’s rapeseeds namely Mustard (Wild), Mustard (hybrid), Rai (Wild), Rai (hybrid) oil on six strains of bacteria in addition to studying the effects of two varieties of rapeseeds oil Mustard (Wild) and Rai (hybrid) oil on Wistar rat’s organs including liver, kidney, heart and skeletal muscles. Firstly, we examined the effects of these Rapeseeds oil on bacteria and found that these Rapeseeds oils possess antibacterial activities. Six bacterial strains such as B. subtilis, S. lutea, X. campestris, E. coli, K. Pneumonia, P. denitrificans was used to test the effect of these rapeseeds oil and observed that rapeseed oil showed inhibition against tested microorganisms in a concentration-dependent manner. Finally, the effects of oil obtained from these two varieties were investigated after feeding rats for 8 weeks. Male Wistar rats were divided into three groups, each group contains 4 rats. Group A was considered as control diet group, while Group B was mustard (Wild) oil group and Group C was Rai (hybrid) oil group. Group A was containing 0.6 gram oil plus 14.4gm diet. We found that rats of both experimental groups exhibit weight loss, reduction of food efficiency ratio and increase cardiac and hepatic enzymes including CK-MB, ALP, SGPT and SGOT compared to the rats fed controlled diet. Furthermore, we also found that the body weight loss, food efficiency ratio markedly decreased and tested enzymes increased in rats fed Mustard (Wild) oil compared to rat fed Rai (hybrid) oil.

Nota. Influencia de la pulpa y fibra natural de algarrobas sobre algunos aspectos de la utilización nutritiva de la dieta y la colesterolemia en ratas / Note. Influence of pulp and natural carob fiber on some aspects of nutritional utilization and cholesterolemia in rats

1999 ◽  
Vol 5 (5) ◽  
pp. 425-430 ◽  
Author(s):  
L. Pérez-Olleros ◽  
M. Garcia-Cuevas ◽  
B. Ruiz-Roso
Keyword(s):  
Comparative Study ◽  
Blood Level ◽  
Serum Cholesterol ◽  
Natural Fiber ◽  
Weight Increase ◽  
Efficiency Ratio ◽  
Semisynthetic Diet ◽  
Food Efficiency ◽  
Cholesterol Levels ◽  
Food Efficiency Ratio

A comparative study of the influence of two subproducts from carob, its pulp (PUL) and its natural fiber (FNA), on the dietary nutritive utilization was performed. The products were included in a semisynthetic diet (50 g/kg) and administered to rats. A group of animals which consumed cellulose (CEL) was used as a control. Cholesterol levels were monitored weekly during 28 days in normal and hypercholesterolemic rats that consumed FNA and CEL (supplemented with sterols 25 g/kg diet). The intake, weight increase and food efficiency ratio (CEA) obtained were not significantly influ enced. By contrast, the fat digestibility coefficient (CDG) of the FNA group (0.97 ± 0.003) was signifi cantly lower than the corresponding CEL (0.98 ± 0.00) and PUL (0.98 ± 0.00) groups. Accordingly, the nitrogen digestibility coefficients (CDN) were significantly different: CEL, 0.93 ± 0.003; PUL, 0.91 ± 0.003, and FNA, 0.90 ± 0.003. Serum cholesterol levels were not different between the non-hypercho lesterolemic groups that consumed FNA or CEL. Concerning the evolution of the cholesterol blood level, the animals supplemented with cholesterol showed an increase that was always lower in the supplemented animals which were administered FNA compared with those that consumed CEL. This difference was statistically significant (p ≤ 0.05) in the fourth week, when the cholesterol levels of the CEL and FNA groups were 235 ± 9 mg/dL and 167 ± 12 mg/dL, respectively.

scholarly journals The Influence of Different Chemical Forms of Selenium Added to the Diet Including Carnosic Acid, Fish Oil and Rapeseed Oil on the Formation of Volatile Fatty Acids and Methane in the Rumen, and Fatty Acid Profiles in the Rumen Content and Muscles of Lambs

2016 ◽  
Vol 66 (3) ◽  
pp. 373-391 ◽  
Author(s):  
Renata Miltko ◽  
J. Agnieszka Rozbicka-Wieczorek ◽  
Edyta Więsyk ◽  
Marian Czauderna
Keyword(s):  
Fatty Acids ◽  
Fish Oil ◽  
Rapeseed Oil ◽  
Volatile Fatty Acids ◽  
Control Diet ◽  
The Body ◽  
Carnosic Acid ◽  
Straight Chain ◽  
Ruminal Fluid ◽  
Branched Chain

AbstractLambs were divided into 3 groups of 6 animals each. For 35 days lambs were fed a diet including 2% rapeseed oil, 1% fish oil and 0.1% carnosic acid (the control group) or two experimental diets supplemented with 0.35 mg ∙ kg−1Se as selenized-yeast (SeY) (the SeY diet) or selenate (the selenate diet). Muscles (Musculus longissimus dorsi(MLD) andMusculus biceps femoris(MBF)), ruminal fluids and microbiota were collected from each lamb. SeY supplementation most effectively stimulated the accumulation of straight-chain volatile fatty acids (VFAs),iso-branched-chain VFAs, CO2and CH4in the ruminal fluid. The contents of CO2, CH4and VFAs including straight-chain VFAs with the exception ofiso-branched-chain VFAs were most effectively reduced by the selenite diet. The control diet most efficiently increased the concentration sums ofodd-saturated fatty acids (odd-SFAs) andiso-SFAs in microbiota. The SeY diet most efficiently reduced acetic acid to propionic acid ratio in the ruminal fluid. The selenate diet improved animal performance by reducing ruminal concentrations of CH4and CO2. The SeY diet and especially the selenate diet reduced the biohydrogenation to C18:0 when compared with the control diet. The selenate diet more efficiently reduced the concentration sums of all SFAs (ΣSFAs) and all fatty acids (ΣFAs) inMLDandMBFthan the SeY diet, which most effectively increased the concentrations of ΣSFAs and ΣFAs inMLDandMBF. The selenate diet most effectively increased the body mass gain of lambs.

scholarly journals Body weight ratio of male and female rats reared on various diets in relation to food efficiency ratio and longevity

1969 ◽  
Vol 3 (2) ◽  
pp. 119-127 ◽  
Author(s):  
L. M. Dalderup
Keyword(s):  
Age Groups ◽  
Weight Ratio ◽  
Later Life ◽  
Female Rats ◽  
Efficiency Ratio ◽  
Male And Female ◽  
Food Efficiency ◽  
Male And Female Rats ◽  
Younger Age ◽  
Food Efficiency Ratio

The ratio of the bodyweights of male and female rats, together with the weight of the females, seems to give valuable information as to the biological value of an experimental food as a whole and to the lifespan expectancy. Extremes of the bodyweight ratios are 0.9 and 2.0, the lower ratios applying to younger age groups and to old animals, the higher ratios to the ages in between. There is evidence that diets which are most favourable with regard to longevity give rise to maximum ratios between 1.5 and 1.6, which are maintained during later life. The females give always less response to dietary measures and are less disturbed by very bad quality rations than the males. Their lifespan is often longer than that of the males. The bodyweight ratio has within reasonable limits the same numerical value as the ratio of food efficiencies of male and female animals; the weight ratio is always very simple to obtain, whereas measurement of food-efficiency ratio requires much more work.

scholarly journals Antiobesity, Regulation of Lipid Metabolism, and Attenuation of Liver Oxidative Stress Effects of Hydroxy-α-sanshool Isolated from Zanthoxylum bungeanum on High-Fat Diet-Induced Hyperlipidemic Rats

2019 ◽  
Vol 2019 ◽  
pp. 1-13 ◽  
Author(s):  
Li Wang ◽  
Wenxiang Fan ◽  
Mengmeng Zhang ◽  
Qing Zhang ◽  
Lin Li ◽  
...  
Keyword(s):  
Body Weight ◽  
High Fat Diet ◽  
Body Weight Gain ◽  
Density Lipoprotein ◽  
The Body ◽  
Efficiency Ratio ◽  
High Fat ◽  
Adipose Tissues ◽  
Food Efficiency Ratio ◽  
Zanthoxylum Bungeanum

Zanthoxylum bungeanum is a traditional Chinese medicine (TCM) used to relieve pain, dispel dampness, stop diarrhea, and prevent itching. The aim of this study was to investigate the antiobesity and hypolipidemic effects of hydroxy-α-sanshool (HAS) isolated from Z. bungeanum on hyperlipidemic rats. Wistar rats (n=48) were randomly divided into six groups: (1) normal diet rats (ND), (2) high-fat diet- (HFD-) treated rats, (3) HFD+fenofibrate-treated rats (HFD+FNB), (4) HFD+low dose of HAS-treated rats (HFD+LD, 9 mg/kg), (5) HFD+middle dose of HAS-treated rats (HFD+MD, 18 mg/kg), and (6) HFD+high dose of HAS-treated rats (HFD+HD, 36 mg/kg). The body weight and food intake of the rats were recorded during the treatment period. After 4 weeks of HAS treatment, abdominal adipose tissues were observed and total cholesterol (T-CHO), triglycerides (TG), high-density lipoprotein (HDL) cholesterol (HDL-C), and low-density lipoprotein (LDL) cholesterol (LDL-C) of serum and liver tissues were determined. Furthermore, histochemical examinations using oil red O and hematoxylin-eosin staining (H&E) were carried out and levels of malondialdehyde (MDA) and glutathione (GSH) and activities of superoxide dismutase (SOD) in the liver were determined. After HFD feeding, the body weight gain and food efficiency ratio of HFD rats were significantly enhanced (p<0.05vs. ND rats) and HAS treatment (18 and 36 mg/kg) significantly decreased the body weight gain and food efficiency ratio (p<0.05vs. HFD rats). In addition, HAS treatment could decrease the abdominal adipose tissues and liver adipocytes. Furthermore, HAS treatment significantly decreased the T-CHO, TG, and LDL-C, whereas it increased HDL-C (p<0.05vs. HFD rats) in serum and the liver. HAS treatment increased the GSH level and SOD activity in the liver (p<0.05vs. HFD rats), whereas it decreased the levels of MDA (p<0.05vs. HFD rats). mRNA analyses suggested that HAS treatment increases the expression of Pparg (proliferator-activated receptor γ) and Apoe (peroxisome apolipoprotein E). Immunohistochemistry and Western blotting indicated that HAS stimulation increased the levels of PPARγ and APOE in the liver, as a stress response of the body defense system. These results revealed that HAS exerts antiobesity and hypolipidemic activities in HFD rats by reducing liver oxidative stress and thus could be considered as a potential candidate drug to cure or prevent obesity and hyperlipidemia.

scholarly journals Thermally oxidised sunflower-seed oil increases liver and serum peroxidation and modifies lipoprotein composition in rats

2004 ◽  
Vol 92 (2) ◽  
pp. 257-265 ◽  
Author(s):  
Carmen Garrido-Polonio ◽  
M. Carmen García-Linares ◽  
M. Trinidad García-Arias ◽  
Sara López-Varela ◽  
M. Camino García-Fernández ◽  
...  
Keyword(s):  
Weight Gain ◽  
Sunflower Seed ◽  
Seed Oil ◽  
Thiobarbituric Acid ◽  
Efficiency Ratio ◽  
Food Efficiency ◽  
Sunflower Seed Oil ◽  
Food Efficiency Ratio ◽  
Liver Tbars ◽  
Lipoprotein Composition

Peroxidation of LDL and other lipoproteins is thought to play a central role in atherogenesis. Dietary thermally oxidised oils may increase atherogenic risk in consumers by increasing their oxidative status. The present paper compares the effects of two diets containing unused sunflower-seed oil (US) or sunflower-seed oil repeatedly used in frying (FS) (both 15 g/100 g diet) on weight gain, food efficiency ratio, serum lipid levels and lipoprotein composition, and the content of thiobarbituric acid-reactive substances (TBARS) in the liver, serum, and lipoproteins in growing Wistar rats. After sixty potato fryings the FS contained 27·7 g polar material/100 g oil and 16·6 g oligomers/100 g oil. The FS-fed rats had a significantly lower weight gain and food efficiency ratio. Liver-TBARS increased due to the consumption of the highly altered oil and showed a significant linear relationship (all r<0·68; P>0·002) with the ingestion of thermally oxidised compounds. Serum-, VLDL-, LDL- and HDL-TBARS were significantly higher in the FS-fed rats (all P>0·001). Concentrations of serum total and non-esterified cholesterol and phospholipids were significantly higher in the FS-fed rats (P>0·05, P>0·05, and P>0·001, respectively). Serum triacylglycerol concentrations did not vary between the two dietary groups. Total and esterified cholesterol and phospholipid levels increased significantly in the HDL fraction (P>0·05, P>0·05, and P>0·001, respectively) of the FS-fed rats. HDL-cholesterol and HDL-phospholipids were significantly correlated with liver-TBARS (r<0·747; P>0·0001), VLDL-TBARS (r<0·642; P>0·003), LDL-TBARS (r<0·475; P>0·04), and HDL-TBARS (r<0·787; P>0·0001). The data suggest that the rat increases HDL as a protecting mechanism against the peroxidative stress induced by the consumption of a diet containing the thermally oxidised oil.

Histomorphometric Alterations in Hepatic Tissue from Malathion-Induced Toxicity: An Experimental Animal Study

2021 ◽  
Vol 10 (1) ◽  
pp. 370-375
Author(s):  
Shazia Parveen Channar ◽  
Nasreen Qazi ◽  
Sajjad Ali Almani ◽  
Sehar Gul Memon ◽  
Mansoor Mukhtar Qazi ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Low Dose ◽  
The Body ◽  
Hepatic Tissue ◽  
Control Group ◽  
High Dose ◽  
Dependent Manner ◽  
Histopathological Changes ◽  
Group A ◽  
Group B

Background: Malathion, a widely used insecticide readily absorbed through skin and seriously affects different tissues and organs of the body. The main objective of this study was to compare the histomorphometric alterations resulting from hazardous effects of different doses of Malathion on hepatic tissue of male albino Wistar rats. Material and Methods: This animal experimental study was conducted at the Department of Anatomy and Postgraduate Research Laboratory at the Isra University, Hyderabad, Sindh Pakistan from February to July 2019. Thirty male albino Wistar rats between 250-300 grams weight were distributed equally into group A (control), group B (low-dose Malathion group; 27mg/kg 1/50 of LD50), and group C (high-dose Malathion group; 50mg/kg). Bodyweight of all rats was taken twice, before and after the experiment. The liver was dissected out, washed and weighed. Histopathological examination was done under the light microscope. Grading was done for severity in histopathological changes in each group. Data was analyzed using one-way ANOVA and Post-hoc Tukey test for comparison with the level of significance set at P-value ≤ .05. Results: Statistically significant (P < .05) decline in body weight was observed in groups B and C in comparison with group A. The relative weight of the liver was increased significantly (P < .05) in the experimental groups, when compared with the control group. Mild-to-moderate histopathological changes were observed in the low-dose Malathion group (Group B) while moderate-to-severe histopathological changes were demonstrated in the high-dose group (Group C). Conclusions: Malathion is a potent toxic pesticide and its exposure can exhibit damage to the hepatic tissues in a dose-dependent manner.

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