scholarly journals HUBUNGAN LAMA TERJADINYA DMT2 DENGAN HEMATOKRIT PADA PASIEN DMT2 DI POLIKLINIK ENDOKRIN BLU RSUP PROF. DR. R. D. KANDOU MANADO

e-CliniC ◽  
2014 ◽  
Vol 2 (2) ◽  
Author(s):  
Christianto A. Y Lumingkewas ◽  
Linda W. A Rotty ◽  
Karel Pandelaki

Abstract: Diabetes mellitus is a metabolic disease characterized by hyper glycemia due to impaired insulin secretion, impaired insulin activity, or both. Chronic hyperglycemia in diabetes is associated with chronic damage and dysfunction of various organs, especially the eyes, kidneys, nerves, heart, and blood vessels. Increased hematocrit can result in impaired blood flow velocity. It is associated with increased blood viscosity causes vasoconstriction of blood vessels due to thickening of the membrane. Research purpose: To determine the correlation between hematocrit and duration of Diabetes Mellitus Type 2 in the polyclinic of endocrinology BLU RSUP Prof. Dr. R. D. Kandou Msnado. Method: The type of this research is descriptive research with cross-analytic sectional study design. In this research intended to analyzing the correlation between hematocrit with long occurs DM type 2. Research results: By using purposive sampling method found 32 people as sample who had been diagnosed with Diabetes Mellitus Type 2. The test result statistic using Speatman Correlation duration of diabetes to hematocrit is obtained numerical coefficients -0.191 and p value of 0.294. Conclusion: From the results of this research indicate that there is no correlation or significant correlation (p>0.294) between hematocrit with long occurs Diabetes Mellitus Type 2. Keywords: Diabetes Mellitus Type 2, hematocrit.     Abstrak: Diabetes melitus merupakan suatu penyakit metabolik yang ditandai dengan hiperglikemi akibat gangguan sekresi insulin, gangguan aktivitas insulin, atau keduanya. Hiperglikemi kronis pada diabetes berhubungan dengan kerusakan kronis dan disfungsi berbagai organ terutama mata, ginjal, syaraf, jantung, dan pembuluh darah.Peningkatan hematokrit dapat mengakibatkan kecepatan aliran darah terganggu. Hal ini berkaitan dengan viskositas darah yang meningkat menyebabkan terjadinya vasokonstriksi akibat penebalan membran pembuluh darah. Tujuan penelitian: Untuk mengetahui hubungan antara hematokrit dan lama terjadinya diabetes melitus tipe-2 di poliklinik endokrin BLU RSUP Prof. Dr. R. D Kandou Manado. Metode: Jenis Penelitian ini adalah penelitian Deskriptif Analitik dengan rancangan penelitian Cross Sectional. Dalam penelitian dimaksudkan untuk menganalisis hubungan antara Hematokrit dengan lama terjadinya DM Tipe-2. Hasil penelitian: Dengan menggunakan metode purrpossive sampling didapatkan 32 orang sebagai sampel yang telah didiagnosis Diabetes Melitus tipe 2. Hasil Uji Statistik Spearman Correlation lamanya diabetes terhadap hematokrit didapatkan angka koefisien sebesar -0,191 dan p value 0,294. Simpulan: Dari hasil penelitian ini menunjukkan bahwa tidak terdapat  korelasi atau hubungan yang bermakna (p>0,294) antara Hematokrit dengan Lama Terjadinya DM tipe 2. Kata kunci: Diabetes Melitus Tipe-2, hematokrit.

2019 ◽  
Vol 8 (2) ◽  
pp. 67-74
Author(s):  
Asri Pandiangan ◽  
Kristian Pieri Ginting

Diabetes melitus  atau DM merupakan kelompok penyakit metabolic dengan karakteristik hiperglikemia yang terjadi akibat kelainan sekresi insulin, kelainan kerja insulin atau kedua-duanya. Prevalensi diabetes melitus pada penduduk usia>15 tahun sebesar 6,9%, Toleransi Glukosa Terganggu atau TGT sebesar 29,9% dan Gula Darah Puasa Terganggu atau GDPT sebesar 36,6%. Diabetes mellitus merupakan silent killer. Adapun gejala-gejala klasik pada diabetes adalah polifagi, polidipsi dan poliuri. Penanganan pasien diabetes terbagi atas terapi farmakologi dan non farmakologi. Literatur review ini bertujuan mengetahui efek pemberian ekstrak biji jintan hitam terhadap pasien diabetes mellitus tipe 2 sebagai terapi alternatif yang sudah dilakukan oleh peneliti sebelumnya. Metode yang digunakan dalam artikel ini adalah penelusuran artikel melalui database NCBI dan Google Scholar. Tahun penerbitan sumber pustaka adalah dari tahun 2001 sampai 2019 dengan 32 sumber pustaka. Berbagai penelitian eksperimental yang dilakukan menunjukkan bahwa kandungan bioaktif pada biji jintan hitam bermanfaat sebagai anti diabetes. Kandungan biji jintan hitam sebagai antioksidan dapat meningkatkan sekresi insulin dengan meningkatkan metabolism energi di mitokondria, meningkatkan jalur intraseluler pada reseptor dan menurunkan glukoneogenesis dengan menekan sintesis enzim glukoneogenik.   Kata kunci: diabetes melitus, thymoquine, anti diabetes   EFFECT OF BLACK SEED EXTRACT FOR DIABETES MELLITUS TYPE 2 AS ALTERNATIVE THERAPY   ABSTRACT Diabetes mellitus or DM  is an group metabolic disease with the hyperglycemia characteristic because of insulin secretion disorder, insulin activity or both of them. The prevalence of diabetes mellitus at the age > 15 years old, is 6.9 percent, 29.9 percent ImpairedGlucoseTolerance or IGT and 36.6 percent ImpairedFastingGlycaemia or IFG.. Diabetes mellitus is a silent killer. As for classic symptoms of diabetes are polyphagia, polydipsia and polyuria. Intervention for patient diabetes divided by pharmacological and non pharmacological intervention. This literature review aims to find out which effect of Black Seed for patient of diabetes mellitus type 2 as alternative therapythat have been done by previous researchers. The method used in this article is the search of articles through the NCBI and Google Scholar databases. The year of publication of library sources is from 2009 to 2018 with 29 library sources.Various experimental research conducted showed part bioactive component useful as antidiabetic. Bioactive component as antioxidant can increase insulin secretion by increasing energy metabolism at mitochondria and increasing intraceluler pathway on insulin receptor and reduce gluconeogenesis by reduce synthesis gluconeogenic enzyme.   Keywords: diabetes mellitus, thymoquinone, anti diabetic


2020 ◽  
Vol 17 (2) ◽  
pp. 110-120
Author(s):  
Tri Yulianti ◽  
Lusi Anggraini

Diabetes mellitus is a chronic metabolic with high prevalence and it can increase the risk of the complications, if it not handled properly. Medication adherence is one of the determining factor to achive therapeutic outcome. This research aims to determine the affecting factors of adherence in  diabetes mellitus type 2 outpatient at RSUD Sukoharjo in 2020. This research type is  cross sectional with a purposive sampling technique. A total of 85 patients diabetes mellitus type 2 outpatient at RSUD Sukoharjo with inclusion criteria received OAD therapy (Oral Antidiabetic Drugs) or a combination of OAD with insulin for at least 1 month, recruited in this study. The data was collected from medical records and questionnaires. Adherence was measured by using the MARS 5 questionnaire (Medication Adherence Report Scale 5). Factors contributing to medication adherence was analyzed by using chi-square test. The results showed that 37 respondents (43.5%) were obedient. The significant factors of medication adherence are monthly income (p-value = 0.018 and OR = 2.887), Medication (p - value = 0.007 and OR = 3,551), the frequency of treatment (p-value = 0.006 and OR = 3,529) and blood glucose level (p-value = 0.006 and OR = 3,529).


2019 ◽  
Vol 6 (3) ◽  
pp. 672
Author(s):  
Erika Martining Wardani ◽  
Lono Wijayanti ◽  
Nur Ainiyah

Diabetes Mellitus (DM) is a metabolic disorder which marked by the hyperglycemia that appeared because of insulin secretion disorder and/or the increase of cellular insulin resistance. DM patients have a higher risk to experience foot problems due to blood vessels disorders causing the circulation of blood from legs is decreased. Purposed this research is diabetes could be prevented by doing a foot spa diabetic which the activities include foot exercises, warm water cleansing and massage. The method used in this study is Quays Experiment pre-post control group design. The population on this study was patients with Diabetes Mellitus Type 2 in Waru health center. The sample used was 60 people, divided into 2 groups; intervention and control group, with sampling technique of simple random sampling. The data collection was using observation sheets of diabetic foot SPA; the tool used to assess blood glucose levels was glucometer, whereas cotton, brush and needle were used to assess the foot sensitivity. The data was then analyzed with t-test. The result of the study showed that there were effecton the foot sensitivity (t=10,73, p value =0, 000) and there were effectdecrese on ankle brachial index(t=12,34, p value =0, 000). It is important for families and communities to give motivation to the diabetes mellitus patients to do diabetic foot SPA as one of alternative therapies to prevent foot complications such as foot ulcers and even amputation


2014 ◽  
Vol 2 (2) ◽  
Author(s):  
Richardo Betteng

Abstract: Diabetes mellitus type 2 is the most common form of diabetes. Approximately 9.7 million women in the United States were diagnosed with diabetes. Indonesia placed the sixth biggest diabetics rank in the world. Diabetes mellitus type 2 often called as lifestyle diabetes because besides hereditary factors, environmental factors such as age, obesity, insulin resistance, diet, physical activity, and lifestyle may cause diabetes. This study aimed to analyze the causes of type 2 diabetes mellitus in productive aged women. This research was conducted using qualitative methods, which produce descriptive data in the form of writings based on informant interviews. There were 10 informants in this study consist of women aged 20-65 years who live around the Wawonasa health centers area. Conclusion: The results of this study were in the form of data from interviews about the risk factors of diabetes mellitus.Keywords : diabetes mellitus type 2, productive aged womenAbstrak: Diabetes melitus tipe 2 merupakan tipe diabetes yang paling umum di temukan. Sekitar 9.7 juta wanita di Amerika terkena diabetes. Indonesia, masuk ke dalam peringkat 6 angka kejadian diabetes melitus terbanyak di dunia. Diabetes melitus tipe 2 sering juga di sebut diabetes life style karena penyebabnya selain faktor keturunan, faktor lingkungan meliputi usia, obesitas, resistensi insulin, makanan, aktifitas fisik, dan gaya hidup juga menjadi penyebab diabetes melitus. Untuk menganalisis faktor penyebab terjadinya diabetes melitus tipe 2 pada wanita usia produktif. Penelitian yang dilakukan menggunakan metode kualitatif, yang menghasilkan data deskriptif berupa tulisan hasil wawancara pada informan. Informan dalam penelitian ini adalah wanita berusia 20 – 65 tahun yang berdomisi di daerah kerja puskesmas wawonasa berjumlah 10 orang. Simpulan: Hasil dari penelitian ini berupa data dari wawancara tentang faktor faktor resiko diabetes melitus.Kata kunci :diabetes melitus, wanita usia produkti


2018 ◽  
Vol 10 (2) ◽  
Author(s):  
Nety Mawarda Hatmanti

Diabetes Mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Diabetes Mellitus type 2 is a significant problem in the global health. This research was purposed to find out the correlation between self-efficacy and quality of life of the patients with Diabetes Mellitus type 2. The design of this research was cross sectional, in which 16 patients visiting the polyclinic of Puskesmas Gayungan Surabaya were chosen as the samples. The result of research using Spearman rho test showed that there was a significant correlation between self-efficacy and quality of life proved by the p value = 0.016 < 0.05. The conclusion of this research found a positive intermediate correlation between selfefficacy and quality of life so that nurses are required to ask the family to increase the patients’ self-efficacy. 


Author(s):  
Rahmadani Sitepu ◽  
Elaninanivi Br Tarigan ◽  
Ida Yustina ◽  
Heru Santoso

Diabetes mellitus is a chronic metabolic disorder which is obtained by absolute or relative insulin deficiency and impaired insulin function. Uncontrolled Diabetes Mellitus can lead to various complications; one of them is macrovascular or microvascular which can be characterized by increasing the blood pressure (hypertension). This study aims to look at the differences of hypertension in the case of controlled and uncontrolled Diabetes Mellitus Type 2 in Pirngadi General Hospital Medan. The type of this research is observational with cross sectional approach. Samples are 42 people. They are taken from medical records and the results will be analyzed by doing univariate and bivariate. The results showed there is a difference between the incidence of hypertension in diabetes mellitus type 2 cases are controlled and uncontrolled in Pirngadi General Hospital Medan Year 2015 where p = 0.0001. Hopefully this research is useful for the public and the health institutions and also for the further researcher


Author(s):  
Mohd Junaid ◽  
Bhavna Singh ◽  
Sahana vats ◽  
Sanandan Thapliyal ◽  
Shalini Thapliyal

The disease Diabetes or Madhumeha is well documented in all perennial sources of Ayurvedic wisdom. The present study was done to evaluate the efficacy of Bimbi (Coccinia indica) in the patients of Diabetes mellitus type-2 through single blind study. Total 30 patients were selected and divided into two groups, 15 patients in each group i.e., A (Bimbi) & B (Barley). In this study it has been found that Madhumeha affects not only in elderly people but in adults too with slight female preponderance. The present study confirmed that after the treatment of 60 days, Bimbi (Coccinia indica) was found effective in treatment of Madhumeha and reduced majority of the symptoms of illness that including Prabootha mootrata (Excessive urination), Atitrushna (Excessive thirst), Avila mootrata (Turbid urine) and Dourbalya (Weakness). There was significant improvement in all the laboratory parameters in patients of Bimbi (Coccinia indica) treated group. The outcome showed that mean reduction in fasting blood sugar level was 19.86%, in PP blood sugar level was 24.52% and in HbA1c level was 8.4%.These outcomes suggest that the results of trial drug i.e., Coccinia indica (Bimbi) powder was highly significant at p-value <0.001. The drug Bimbi showed effectiveness in reducing FBS, PPBS and HbA1c, as results were highly significant. Barley powder used as placebo didn't showed reduction in FBS, PPBS and HbA1c.


2014 ◽  
Vol 7 ◽  
pp. CMED.S13573 ◽  
Author(s):  
Omar Al-Attas ◽  
Nasser Al-Daghri ◽  
Majed Alokail ◽  
Sherif Abd-Alrahman ◽  
Benjamin Vinodson ◽  
...  

Thiamine deficiency has been documented to be prevalent in patients with diabetes mellitus, and correction of thiamine deficiency in this population may provide beneficial effects in several cardiometabolic parameters, including prevention of impending complications secondary to chronic hyperglycemia. In this interventional study, we aim to determine whether thiamine supplementation is associated with cardiometabolic improvements in patients with diabetes mellitus type 2 (DMT2). A total of 86 subjects (60 DMT2 and 26 age- and BMI-matched controls) were included and were given thiamine supplements (100 mg/day) for six months. Anthropometrics and metabolic profiles were measured routinely. Serum thiamine and its derivatives were measured using high performance liquid chromatography. In all groups, there was a significant decrease in total cholesterol after three months ( p = 0.03) as well as in HDL cholesterol after six months of thiamine supplementation ( p = 0.009). Significant improvements were also observed in the mean serum levels of creatinine ( p = 0.001), as well as thiamine and its derivatives in both serum and urinary levels across follow-up visits ( p-values 0.002 and <0.001, respectively). In the DMT2 group, improvements were observed in lipid profile (mean serum LDL and total cholesterol with ^-values 0.008 and 0.006, respectively), serum thiamine ( p < 0.001), TMP ( p < 0.001), TDP ( p < 0.001), urinary thiamine ( p < 0.001) and serum creatinine ( p < 0.001). Thiamine supplementation is a promising adjuvant therapy for patients with DMT2. Longer clinical trials are needed to determine its protective effect in DMT2 complications.


2021 ◽  
pp. 83-92
Author(s):  
Yusran Hasymi ◽  
. Suwanto

Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia, which occurs due to abnormalities in insulin secretion, insulin action, or both. Most cases of diabetes mellitus are diabetes mellitus type-2. The purpose of this study was to determine the effect of hypnotherapy on reducing blood glucose levels in patients with diabetes mellitus type-2. The research used a quasi-experimental design with a non-equivalent control group design. Purposive sampling was used, and 30 respondents selected. The instrument in this study was a single stick tool. The intervention group was given standard therapy treatment in the form of bio-energy therapy and hypnotherapy, while the control group was only given standard therapy treatment in the form of bio-energy therapy. Univariate analysis of the results indicates that the average blood glucose level before treatment was 234.67 mg/dl and after treatment was 194.67 mg / dl. Bivariate analysis based on the results of the Wilcoxon Signed Ranks Test obtained a p-value of 0.002 (p-value <0.05). This means that hypnotherapy reduced blood glucose levels in diabetes mellitus type-2 sufferers. This study recommends the nursing profession apply hypnotherapy as an alternative or non-pharmacological complementary therapy that can be used to reduce blood glucose levels in people with diabetes mellitus type 2.   Keywords: Hypnotherapy, diabetes mellitus type 2, blood glucose levels


Sign in / Sign up

Export Citation Format

Share Document