scholarly journals Perbandingan Perubahan Kadar Gula Darah Sebelum Pembedahan, 30 Menit dan 60 Menit Saat Pembedahan dengan Anestesi Umum dan Anestesi Spinal

e-CliniC ◽  
2017 ◽  
Vol 5 (2) ◽  
Author(s):  
Muh A.N Yaqin ◽  
Harold F. Tambajong ◽  
Barry I. Kambey
Keyword(s):  
Blood Glucose ◽  
Stress Response ◽  
Blood Glucose Level ◽  
General Anesthesia ◽  
Spinal Anesthesia ◽  
Glucose Level ◽  
The Body ◽  
Consecutive Sampling ◽  
Significant Difference ◽  
Mean Blood Glucose

Abstract: Anesthesia and surgery could cause stress response within the body that affects blood glucose level. This study was aimed to compare blood glucose levels at 30 minutes and 60 minutes during surgery using general anesthesia and spinal anesthesia. This as an observational prospective analytical stdy with a cross-sectional design performed on 12 patients gathered through consecutive sampling that fulfilled inclusion and exclusion criteria. The patients were divided into 2 groups: those undergoing surgery with general anesthesia and those with spinal anesthesia. Measurement of blood glucose level was done 3 times, 2 hours before premedication induction, 30 minutes and 60 minutes during surgery. Data were analyzed statistically by using the Shapiro-Wilk test, the T-independent test, and the Mann Whitney. The results showed that there was no significant difference between blood glucose level at 30 minutes during surgery using general anesthesia and spinal anesthesia (P = 0.23), however, there was a significant difference between blood glucose level at 60 minutes during surgery using general anesthesia and spinal anesthesia (P=0.03). Mean blood glucose level at30 minutes during surgery with general anesthesia was 103 mg/dl and at 60 minutes during surgery was 116.7 mg/dl, while mean blood glucose level at 30 minutes during surgery using spinal anesthesia was 93.50 mg/dl and at 60 minutes during surgery was 94.50 mg/dl. Conclusion: There was a significant difference in blood glucose level between general anesthesia and spinal anesthesia at 60 minutes during surgery.Keywords: stress response, blood glucose level, general anesthesia, spinal anesthesia Abstrak: Anestesi dan pembedahan dapat menyebabkan terjadinya suatu respon stres pada tubuh yang memengaruhi kadar gula darah. Penelitian ini bertujuan untuk membandingkan kadar gula darah 30 menit dan 60 menit saat pembedahan dengan anestesi umum dan anestesi spinal. Jenis penelitian ialah observasional analitik prospektif dengan desin potong lintang. Penelitian dilakukan terhadap 12 pasien yang didapatkan secara consecutive sampling dan memenuhi kriteria inklusi dan eksklusi, lalu dibagi menjadi 2 kelompok, yaitu kelompok yang menjalani pembedahan dengan anestesi umum dan kelompok yang menjalani menjalani pembedahan dengan anestesi spinal. Pengukuran kadar gula darah dilakukan 3 kali, yaitu 2 jam sebelum induksi premedikasi, serta 30 menit dan 60 menit saat pembedahan. Analisis statistik dilakukan dengan uji Shapiro-Wilk, uji T-Independen,, dan uji Mann Whitney. Hasil penelitian menunjukkan tidak terdapat perbedaan bermakna antara kadar gula darah 30 menit saat pembedahan dengan anestesi umum dan anestesi spinal (P=0,23) sedangkan pada 60 menit saat pembedahan menunjukkan adanya perbedaan bermakna antara kadar gula darah 60 menit saat pembedahan dengan anestesi umum dan anestesi spinal (P=0,03). Rerata kadar gula darah 30 menit saat pembedahan dengan anestesi umum yaitu 103 mg/dl dan 60 menit saat pembedahan yaitu 116,7 mg/dl, sedangkan rerata kadar gula darah 30 menit saat pembedahan dengan anestesi spinal yaitu 93,50 mg/dl dan 60 menit saat pembedahan yaitu 94,50 mg/dl. Simpulan: Perubahan kadar gula darah yang bermakna antara anestesi umum dan anestesi spinal terjadi pada 60 menit saat pembedahan.Kata kunci: respon stres, kadar gula darah, anestesi umum, anestesi spinal

scholarly journals Penurunan Kadar Glukosa Darah Sewaktu Melalui Terapi Reiki Pada Pasien Diabetes Melitus Tipe 2

2011 ◽  
Vol 14 (2) ◽  
pp. 113-120
Author(s):  
Ester Inung Sylvia ◽  
Krisna Yetti ◽  
Rr.Tutik Sri Hariyati
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Complementary Therapy ◽  
The Body ◽  
Purposive Sampling ◽  
Significant Difference ◽  
Decrease Blood Glucose ◽  
Diabetes Melitus

AbstrakReiki merupakan terapi komplementer untuk menurunkan kadar glukosa darah. Terapi ini menggunakan energi alami yangdisalurkan pada tubuh pasien dengan tujuan menyelaraskan energi yang tidak seimbang dalam tubuhnya. Penelitian untukmengetahui pengaruh Reiki terhadap penurunan glukosa darah dan mengidentifikasi apakah faktor stres dan berat badan(obesitas) berperan dalam penurunan KGD pasien Diabetes Melitus tipe 2 dilakukan di Klub Diabetes sebuah RS di Jakarta.Desain penelitian pre-eksperimental dengan pendekatan one-group pretest-posttest design. Sejumlah 18 sampel dipilih denganteknik purposive sampling. Terapi dilakukan selama tiga puluh hari dengan dua metode, secara langsung dan jarak jauh. Hasilpenelitian menunjukkan perbedaan bermakna antara glukosa darah sebelum dan setelah intervensi Reiki (p= 0,000; α= 0,05).Penelitian ini menyarankan penggunaan Reiki dalam asuhan keperawatan.Kata Kunci: diabetes melitus tipe 2, kadar glukosa darah, Reiki, terapi komplementerAbstractReiki is one of the complementary therapies that are used to decrease blood glucose level. The therapy transfers naturalenergy into the patient’s body to synchronize the energy imbalance in the body. The research to examine the effect of Reiki andthe role of the stress and weight factor to decrease blood glucose level of DM type 2 patients was held in a hospital-baseddiabetic club in Jakarta. The design of this study was pre-experimental with the one-group pretest-posttest design. Eighteenpatients were selected with the purposive sampling technique. Reiki therapy was performed in 30 days using two methods:direct and distant healing method. The result revealed that there was a significant difference in random blood glucose levelbefore and after the Reiki intervention (p= 0.000; α= 0.05). It is recommended to incorporate the Reiki therapy in nursingcare.Keywords: type 2 Diabetes Mellitus, blood glucose level, Reiki, complementary therapy

scholarly journals Hypoglycemic and antioxidative activities of ethanol seed extract of Hunteria umbellate (Hallier F.) on streptozotocin-induced diabetic rats

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Olubanke O. Ogunlana ◽  
Babatunde O. Adetuyi ◽  
Miracle Rotimi ◽  
lohor Esalomi ◽  
Alaba Adeyemi ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Fasting Blood Glucose ◽  
Diabetic Rats ◽  
Seed Extract ◽  
The Body ◽  
High Concentration ◽  
Group 5

Abstract Background Diabetes, a global cause of mortality in developing countries is a chronic disorder affecting the metabolism of macromolecules and has been attributed to the defective production and action of insulin characterized by persistent hyperglycemic properties. This global disorder harms organs of the body such as the liver, kidney and spleen. Medicinal plants such as Hunteria umbellate have been shown to possess hypoglycemic, antioxidative and anti-diabetic properties owing to the high concentration of active phytochemical constituents like flavonoids and alkaloids. The present study seeks to evaluate the hypoglycemic activities of ethanolic seed extract of Hunteria umbellate on streptozotocin-induced diabetes rats. Methods Thirty (30) female experimental rats were randomly divided into five groups with six rats per group and were administered streptozotocin (STZ) and Hunteria umbellate as follows. Group 1 served as control and was given only distilled water, group 2 rats were administered 60 mg/kg STZ; Group 3 was administered 60 mg/kg STZ and 100 mg/kg metformin; group 4 rats were administered 60 mg/kg STZ and 800 mg/kg Hunteria umbellate, group 5 rats 60 mg/kg STZ and 400 mg/kg Hunteria umbellate. The fasting blood glucose level of each rat was measured before sacrifice. Rats were then sacrificed 24 h after the last dose of treatment. Results The results showed that Hunteria umbellate significantly reversed STZ-induced increase in fasting blood glucose and increase in body and organs weight of rats. Hunteria umbellate significantly reversed STZ-induced decrease in antioxidant enzyme in liver, kidney and spleen of rats. Hunteria umbellate significantly reversed STZ-induced increase in oxidative stress markers in liver, kidney and spleen of rats. Conclusion Collectively, our results provide convincing information that inhibition of oxidative stress and regulation of blood glucose level are major mechanisms through which Hunteria umbellate protects against streptozotocin-induced diabketes rats.

scholarly journals Comparison between the QRMA Measurement with the Anamnesis and the Capillary Blood Glucose Test

Jurnal NERS ◽  
2020 ◽  
Vol 14 (2) ◽  
pp. 224
Author(s):  
Muflih Muflih ◽  
Suwarsi Suwarsi ◽  
Fajarina Lathu Asmarani
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Level ◽  
Blood Sugar ◽  
Glucose Level ◽  
Blood Sugar Level ◽  
Capillary Blood ◽  
Capillary Blood Glucose ◽  
Blood Glucose Test ◽  
Significant Difference ◽  
Glucose Test

ABSTRACTIntroduction: The examination of patients with diabetes mellitus (DM) can be done by reviewing their complaints and through a capillary blood glucose level test to determine the value of their Random Blood Glucose Level. QRMA (Quantum Resonance Magnetic Analyzer) is claimed to be able to check the patient’s bodily condition (including blood glucose) with an accuracy of 85%. The purpose of this study was to verify the validity of the QRMA tool and its accuracy by comparing the results of the anamnesis and the examination conducted using the capillary blood glucose test method.Methods: The research method used was a cross-sectional design. The total sample consisted of 44 respondents in the working area of the Community Health Centers in Yogyakarta with the risk factor being blood sugar level instability. The sampling technique used was purposive sampling. The main variable in this study was the value of the blood sugar level measured based on the coefficient value of the QRMA tool and the value of Random Blood Glucose obtained through the capillary blood glucose test.Results: The blood glucose value was not correlated significantly with the coefficient value of QRMA. The value of blood glucose when examined alongside the result of the respondent's anamnesis showed there to be a significant difference. The value of the QRMA coefficient when examined against the results from the history of the respondents showed no significant difference. Linear regression showed that the variables of height, body weight, and IMT had a correlation with the QRMA coefficient value.Conclusion: The QRMA tool was not able to provide a picture of the actual condition of the blood glucose level of the respondents when compared with the results of the anamnesis and the blood glucose value from the capillary blood glucose test. Non-invasive health measurement devices such as QRMA are not used by nurses as a standard for determining the health status of DM patients.

COMPARISON OF THE EFFECT OF DEXAMETHASONE ON THE BLOOD GLUCOSE LEVEL IN PREGNANT AND NON-PREGNANT WOMEN UNDER GENERAL ANESTHESIA

2021 ◽  
Vol 74 (9) ◽  
pp. 2277-2280
Author(s):  
Hanan Fawzi ◽  
Alaa Hussen Ali
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Level ◽  
General Anesthesia ◽  
Pregnant Women ◽  
Glucose Level ◽  
Elective Cesarean Section ◽  
Glucose Levels ◽  
Anesthetic Drugs ◽  
Study Results ◽  
Blood Glucose Concentrations

The aim: To compared blood glucose concentrations after intravenous injection of dexamethasone in the pregnant and non-pregnant women under general anesthesia. Materials and methods: Eighty patients aged 18-50 years took part in the study (ASA class 1 and 2). Forty of patients were undergoing elective cesarean section under G/A and the other forty undergoing elective laparoscopic Cholecystectomy under G/A. Anesthesia was induced using IV anesthetic drugs (0.5mg/kg ketamine, sleeping dose of propofol up to 2mg/kg, muscle relaxant was 0.6 mg/kg rocuronium and maintained with isoflurane). All of patients have been injected with 0,1mg/kg dexamethasone intravenously, at induction of anesthesia, Blood glucose concentrations were measured at induction and then in 60min, 180min and in 360 min after injection of dexamethasone and results were compared between the groups; IV fluid added was normal saline (0.9%) during the study. Results: Regarding to blood glucose levels, we noticed that its level significantly increased over time and peaked in 180min after dexamethasone injection in both groups. The difference percentage between the lower reading (pre injection) and the upper reading (in 180min after) was 33.5% in pregnant woman and 46.2%for non-pregnant women, this difference was statistically significant relative to the pre injection, as this difference was lower in the pregnant women. In 360min after blood glucose level began to drop in both groups. After giving 0.1 mg/kg of dexamethasone, blood glucose level increased in both groups, but it was lower in pregnant women.

Impact of muscle mass on blood glucose level

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Murtada Taha ◽  
Yaser A. AlNaam ◽  
Thekra Al Maqati ◽  
Lenah Almusallam ◽  
Gharam Altalib ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Level ◽  
Muscle Mass ◽  
Glucose Level ◽  
Glucose Utilization ◽  
Treatment Modalities ◽  
Healthy Population ◽  
Inverse Association ◽  
Significant Difference ◽  
The Mean

Abstract Objectives At present, diabetes is one of the leading causes of mortality across the world. It was hypothesized that muscle mass could have a significant influence on blood glucose level and this corelation if established successfully could pave way for novel treatment modalities for type 2 diabetes mellitus (T2DM). In the present study, the association between muscle mass and blood glucose level was examined in a healthy population who was not having T2DM at baseline and was undergoing a regular course of exercise. Methods The clinical study was performed involving 53 healthy male populations between 10 and 60 years of age. The participants were sampled in accordance with the quantitative experimental study design, using nonprobability sampling techniques. The independent variable measured among the subjects included muscle mass and blood glucose level, using bioelectrical impedance and a simple glucometer respectively. Subgroup analysis amongst different substantial parameters including body mass index (BMI), myostatin inhibitor usage, and age factor that could affect the muscle mass and glucose level correlation were also studied simultaneously. Results The study findings demonstrated a negative correlation between muscle mass and glucose utilization levels. There was a significant difference in the mean muscle mass of the participants which was 36.2453, and the mean glucose utilization level which was 15.1493%. Pearson correlation between the muscle mass and percentage of glucose utilization of the participants indicated a significant difference (since p-value <0.05) between these two studied parameters. Conclusions The study finding suggests an inverse association of the skeletal muscle mass with blood glucose level which encourages the implication of muscle-building exercises as the preventive measure for T2DM.

UJI PERBANDINGAN EFEKTIVITAS ANTIDIABETES EKSTRAK POLISAKARIDA DAN SENYAWA POLIFENOL ALGA COKLAT (Sargassum sp.) PADA MENCIT YANG DIINDUKSI ALOKSAN

2018 ◽  
Vol 4 (1) ◽  
pp. 48
Author(s):  
Agung Giri Samudra ◽  
Fathur Sani K ◽  
Moniq Chintama
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Brown Algae ◽  
Positive Control ◽  
Negative Control ◽  
The Body ◽  
Group Iii ◽  
Percentage Decrease ◽  
Polyphenolic Extract

Diabetes is one of the most common diseases in the world. So there is an effort to prevent or treat the disease. As brown algae (Sargassum sp.) Contains polysaccharides that regulate sugar intake in the body, and polyphenols act as antioxidants that can stimulate insulin secretion in pancreatic β cells. This study aims to determine the effectiveness of Antidiabetes Polysaccharide Extract and Brown Algae Polifenol Compounds (Sargassum sp) On Alloxaninduced Mice. The test animals were grouped into 4 groups I (CMC 1%), Group II (Glibenclamide 0.52mg / 20grBB), Group III (5mg / 20grBB polyphenol extract), Group IV (5mg / 20grBB polysaccharide extract). Blood glucose was measured using Easy touch glucometer on days 0, 3, 7, 14, 21, and 28. Analyze data using one-way ANOVA, followed by LSD test. The percentage decrease in blood glucose level in positive control, polyphenol extract and polysaccharide were 42,86%, 58,12%, and 54,20%. Statistically, the polyphenolic extract and the brown algae polysaccharide lower the blood glucose level significantly compared with the negative control (p≤0,05). Decreased blood glucose in polyphenol extracts and polysaccharides showed statistically significant differences

Hepatoproective Nature of Aerial parts of Caesalpinia pulcherrima in STZ Induced Diabetic Rat Model

2021 ◽  
pp. 3716-3720
Author(s):  
Pooja Pooja ◽  
Mazumder Avijit ◽  
Soumya Das
Keyword(s):  
Body Weight ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Diabetic Rats ◽  
The Body ◽  
Marker Enzymes ◽  
Metabolizing Enzymes ◽  
Standard Drug ◽  
Liver Marker Enzymes

Diabetes is a chronic disease which characterized by hyperglycemia (elevated or abnormally high blood sugar levels) and other metabolic disturbances, including metabolism of lipids and haemostasis. Caesalpinia pulcherrima has previously showed strong anti-diabetic and hepatoprotective potential. The present research work was to investigate the anti-diabetic activity and hepatoprotective activity Caesalpinia pulcherrima in streptozotocin-induced (STZ) diabetic rats. The dose-dependent effects of 45days oral treatment with methanol extract of plant (200 and 300mg/kg) of CPAE on body weight, blood glucose level, total protein, albumin, liver marker enzymes and carbohydrate metabolizing enzymes were evaluated in STZ-induced diabetic rats. Oral administration methanolic extract of Caesalpinia pulcherrima of showed significant restoration of the body weight and decrease in the blood glucose level, liver marker enzymes (ALT, AST ALP) and carbohydrate metabolizing enzymes were observed in diabetic rats. These results suggest that fruit extract of Caesalpinia pulcherrima has valuable anti-diabetic activity in STZ-induced diabetic rats which is comparable to the standard drug metformin and hence might be of use in the management of diabetes.

scholarly journals The Impact of Preoperative Fasting Duration on Blood Glucose and Hemodynamics in Children

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Pouran Hajian ◽  
Minoo Shabani ◽  
Elham Khanlarzadeh ◽  
Mahshid Nikooseresht
Keyword(s):  
Blood Pressure ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Systolic Blood Pressure ◽  
Glucose Level ◽  
Anesthesia Induction ◽  
Preoperative Fasting ◽  
Mean Blood Glucose ◽  
Fasting Duration ◽  
The Impact

Background. Prolonged preoperative fasting is one of the concerns of pediatricians and anesthesiologists in pediatric surgery. The aim of this study was to assess the impact of preoperative fasting duration on blood glucose and hemodynamics in children. Methods. This cross-sectional study was conducted on 50 children who were between the ages of 3 and 12 years in Besat Hospital, Hamedan, Iran. The time of the last solid and liquid meal taken by child were recorded based on interview with the parents. The first blood glucose test was obtained in the operation room, and the second test was performed 20 minutes after induction of anesthesia by glucometer. Systolic blood pressure (SBP), mean arterial pressure (MAP), and heart rate (HR) were recorded before anesthesia induction and in five-minute intervals in the first 20 minutes of surgery. Results. The mean age of the children was 6.63 (SD 1.85) years. Mean blood glucose 20 minutes after surgery was 101.17 (SD 92) mg/dl, which was significantly higher than the baseline values (87.66 (SD 11.84) mg/dl) (P<0.001). The comparison of mean blood glucose level between groups of fasting with different duration for solids (<12 hours and >12 hours) and for liquids (<6 hours and >6 hours) revealed no significant difference in either groups (P>0.05). No significant correlation was observed between blood glucose level at the induction of anesthesia with weight and age (P>0.05). There was a significantly negative correlation between duration of fasting for liquids and SBP (P>0.05). Conclusion. Prolonged preoperative fasting cannot affect blood glucose in children; however, maybe it has impact on systolic blood pressure.

scholarly journals EFFECT OF AEROBIC EXERCISES AND RESISTANCE TRAINING ON GLUCOSE LEVELS IN TYPE 2 DIABETIC SUBJECTS.

2017 ◽  
Vol 10 (7) ◽  
pp. 360
Author(s):  
Aishwarya Pramod Benkar ◽  
Smita Bhimrao Kanase
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Resistance Training ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Postprandial Blood Glucose ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Significant Difference

Objective: Diabetes mellitus is a leading cause of death and disability in the world and its prevalence is predicted to rise to 10% by 2030. Hence, this study is conducted with objectives to find out the effect of aerobic exercises and resisted exercises on blood glucose levels in type 2 diabetes mellitus (T2DM) subjects and to compare the effect of both exercises on blood glucose level.Method: The comparative study was conducted at Krishna Institute of Medical Sciences Deemed University, Physiotherapy department, Karad. 30 participants with age group between 30 and 65 years were taken. Subjects were selected as per inclusion and exclusion criteria. Group A (15) participants were given aerobic exercise on static bicycle, and Group B (15) participants were given resistance training using dumbbells and weight cuffs for 5 days/week for 4 weeks. Diet recommendations were given to every participant.Results: Statistical analysis was performed using paired and unpaired t-test. Analysis showed statistically extremely significant difference in fasting blood glucose level and postprandial blood glucose level in both the groups (p≤0.0001).Conclusion: Thus, this study concludes that both aerobic exercises and resistance training prove to be beneficial in controlling blood glucose levels in T2DM subjects.

scholarly journals Lactobacillus rhamnosus Reduces Blood Glucose Level through Downregulation of Gluconeogenesis Gene Expression in Streptozotocin-Induced Diabetic Rats

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Eko Farida ◽  
Lilis Nuraida ◽  
Puspo E. Giriwono ◽  
Betty S. L. Jenie
Keyword(s):  
Blood Glucose ◽  
Glucose Tolerance ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Fasting Blood Glucose ◽  
Lactobacillus Rhamnosus ◽  
Tolerance Test ◽  
Diabetic Rats ◽  
The Body ◽  
Oral Glucose

Some lactic acid bacteria (LAB) are observed to be potential probiotics with functional properties such as lowering fasting blood glucose (FBG), as a promising hyperglycemia management. This study investigated the ability and mechanism of Lactobacillus rhamnosus BSL and Lactobacillus rhamnosus R23 on lowering FBG in diabetic rats induced by streptozotocin (STZ). The rats were orally administered with L. rhamnosus BSL and L. rhamnosus R23 by giving 1 mL cell suspension (109 CFU/mL) daily for 30 days. The body weight (BW) was recorded once in three days, and FBG was recorded once in six days. An oral glucose tolerance test (OGTT) was measured 1 week after injection with STZ and before sacrifice. Fecal samples were collected on days 0, 15, and 30 for LAB population and identification, performed by PCR detecting 16S rRNA. Oral administration of L. rhamnosus BSL and L. rhamnosus R23 decreased FBG and improved glucose tolerance via downregulation of glucose-6-phosphatase (G6pc) expression by 0.57- and 0.60-fold change, respectively (P<0.05). The lipid profiles, BUN, creatinine, SGOT, and SGPT were significantly (P<0.05) different between normal and diabetic rats, but they were not significantly (P>0.05) different among diabetic rats. Both strains were effective in increasing fecal LAB population. Molecular identification of the isolated LAB from fecal sample indicated that they were able to survive and pass through the digestive tract. These results suggested that both strains have the ability to manage blood glucose level and become a promising agent to manage hyperglycemia and diabetes.

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