scholarly journals Pembentukan Mikronukleus di Mukosa Bukal akibat Paparan Senyawa Kimia pada Berbagai Macam Pekerjaan

e-GIGI ◽  
2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Deny Setiabudi ◽  
Rizki Amalina ◽  
Anggun Feranisa

Abstract: In general, an occupation could have hazzard and risk of exposure to genotoxic chemical compounds. These compounds could lead to micronucleus formation on buccal mucosa. This study was aimed to obtain the impact of chemical exposure on micronucleus formation in buccal mucosa at various occupations. This was a literature review study using databases of PubMed, ScienceDirect, and Google Scholar based on the keywords. The criteria of literatures were articles published in 2016-2021 using Indonesian or English language. The results showed that  group compounds of polycyclic aromatic hydrocarbons (PAH), metals, carbamate, and organophospate, also compunds of silica, bezene, toluene, xylene (BTX), sevoflurane, desflurane, isoflurane, nitrous oxide, gemcitabin, and 5-fluoro uracil were genotoxic chemical compunds and could cause micronucleus formation in buccal mucosa of mechanics, grillers, miners, e-waste recyclers, construction workers, road markers, car painters, gasoline station workers, farmers, and healthcare workers. Genotoxic chemical compounds could be found excessively in occupational environment. These compounds could damage cells’ DNA and caused micronucleus formation on buccal mucosa of workers. It is suggested to study further about cell damage biomarkers caused by genotoxic chemical compound exposure.Keywords: micronucleus formation in buccal mucosa, chemical exposure of genotoxic compounds, occupational riskAbstrak: Suatu pekerjaan dapat memiliki risiko dan bahaya terpapar senyawa kimia yang bersifat genotoksik. Senyawa kimia tersebut dapat menyebabkan terbentuknya mikronukleus di mukosa pipi rongga mulut. Penelitian ini bertujuan untuk mengulas pengaruh paparan senyawa kimia pada berbagai macam pekerjaan terhadap pembentukan mikronukleus di mukosa bukal. Jenis penelitian ialah literature review. Penelusuran literatur melalui database PubMed, ScienceDirect, dan Google Scholar berdasarkan kata kunci yang sesuai. Kriteria literatur ialah terbitan tahun 2016-2021 dengan Bahasa Indonesia atau Inggris. Hasil penelitian mendapatkan senyawa kelompok polycyclic aromatic hydrocarbon (PAH), logam, carbamate, dan organophospate, serta senyawa silica, benzene, toluene, xylene (BTX), sevoflurane, desflurane, isoflurane, nitrous oksida, gemcitabin, dan 5-fluoro uracil merupakan senyawa kimia yang bersifat genotoksik dan dapat memicu pembentukan mikronukleus di mukosa bukal mekanik, pemanggang daging, penambang, pendaur ulang sampah elektronik, pekerja konstruksi, pekerja marka jalan, pengecat mobil, petugas SPBU, petani dan tenaga kesehatan. Senyawa kimia yang bersifat genotoksik banyak ditemukan di lingkungan pekerjaan. Senyawa tersebut dapat merusak DNA sel sehingga terbentuk mikronukleus di mukosa bukal pekerja. Disarankan untuk melakukan penelitian lanjut mengenai biomarker kerusakan sel akibat paparan senyawa kimia yang genotoksik.Kata kunci: pembentukan mikronukleus di mukosa pipi, paparan senyawa kimia genotoksik, risiko pekerjaan

2021 ◽  
Vol 3 (1) ◽  
pp. 61
Author(s):  
Christesa Y. Palawe ◽  
Carla F. Kairupan ◽  
Poppy M. Lintong

Abstract: Medicinal plant that contain antioxidants is an alternative therapeutic option for liver disorders. This study was aimed to review the hepatoprotective effects of medicinal plants. This was a literature review study using PubMed, Google Scholar and Clinical Key. The results showed 10 hepatoprotective medicinal plants, as follows:  soursop leaves, yellow bamboo shoots, moringa leaves, green betel leaves, libo fruit, kenikir, neem leaves, bitter bean seeds, black cumin, and solo garlic. All of them showed hepatoprotective activities based on the results of the tests, using biochemical and histopathological parameters. Soursop leaves could increase SOD level and reduce MDA level; yellow bamboo shoots were demonstrated to maintain SGPT activities and bilirubin level; moringa leaves have been associated with the reduction of MDA, SGOT, and SGPT levels; green betel leaves were able to reduce SGOT and SGPT levels and improve liver centrolobular necrosis; libo fruit was able to lower SGPT level; kenikir and bitter bean seeds were shown to reduce SGOT and SGPT levels; neem leaves were associated with the reduction of ALT level and protection against liver cell damage; black cumin was found to reduce fat degeneration; solo garlic could reduce MDA, SGPT, and SGOT levels, and maintain SOD level. In conclusion, the 10 hepatoprotective medicinal plants have the ability to increase SOD levels, reduce SGOT, SGPT and MDA levels, maintain bilirubin levels, regenerate centrilobular necrosis of the liver, and reduce fat degeneration of the liver. Solo garlic shows the largest amount of hepatoprotective activities, followed by yellow bamboo shoots, green betel leaves and libo fruit.Keywords: medicinal plants, hepatoprotector effect  Abstrak: Pengobatan menggunakan tanaman obat yang mengandung antioksidan merupakan pilihan terapi alternatif untuk gangguan pada hati. Penelitian ini bertujuan untuk menelaah efek hepatoprotektif tanaman obat. Jenis penelitian ialah literature review dengan menggunakan PubMed, Google Scholar dan Clinical Key. Hasil penelitian mendapatkan 10 tanaman obat hepatoprotektor yaitu daun sirsak, rebung bambu kuning, daun kelor, daun sirih hijau, buah libo, kenikir, daun mimba, biji petai, jintan hitam, dan bawang lanang. Tanaman-tanaman obat tersebut memiliki aktivitas hepatoprotektif berdasarkan pengujian dengan parameter biokimia dan histopatologi. Daun sirsak dapat meningkatkan kadar SOD dan menurunkan kadar MDA; rebung bambu kuning dapat mempertahankan aktivitas SGPT dan kadar bilirubin; daun kelor menurunkan kadar MDA, SGOT, dan SGPT; daun sirih hijau menurunkan kadar SGOT dan SGPT, serta memperbaiki nekrosis sentrolobuler hati; buah libo menurunkan kadar SGPT; kenikir dan biji petai menurunkan kadar SGOT dan SGPT; daun mimba menurunkan kadar SGPT dan memiliki daya proteksi terhadap kerusakan sel hati; jintan hitam dapat mengurangi degenerasi lemak; bawang lanang menekan peningkatan kadar MDA, SGPT, SGOT dan mempertahankan kadar SOD. Simpulan penelitian ini Kesepuluh tanaman obat hepatoprotektor tersebut memiliki kemampuan dalam meningkatkan kadar SOD, menurunkan kadar SGOT, SGPT dan MDA, mempertahankan kadar bilirubin, memperbaiki nekrosis sentrolobuler hati, dan mengurangi degenerasi lemak hati. Bawang lanang menunjukkan aktivitas hepatoprotektor terbesar, diikuti rebung bambu kuning, daun sirih hijau, dan buah libo.Kata kunci: tanaman obat, efek hepatoprotektor


Jurnal Surya ◽  
2019 ◽  
Vol 11 (03) ◽  
pp. 40-46
Author(s):  
Asra Dewi

Catatan keperawatan adalah suatu laporan baik komunikasi secara lisan, tertulis maupun melalui komputer untuk menyampaikan informasi kepada orang lain. Perkembangan teknologi informasi digital yang sangat cepat dalam dunia kesehatan, membawa dampak pada kemajuan yang cukup berarti dalam bidang keperawatan. Catatan keperawatan dari yang sebelumnya manual, bergeser menjadi komputerisasi. Tujuan penulisan ini  untuk melihat dampak penerapan sistem pencatatan keperawatan elektronik. Metode yang digunakan adalah literature review, pencarian menggunakan beberapa database elektronik, yakni Google Scholar, ProQuest, SpringerLink, CINAHL dan ScienceDirect dengan menggunakan kata kunci the impact of electronic nursing recording systems, information technology. Hasil telaah ditemukan bahwa penerapan sistem pencatatan keperawatan elektronik ini memberikan dampak terhadap peningkatan kualitas asuhan keperawatan, efisiensi dan keamanan data pasien. Kesimpulannya diperlukan dukungan manajer dan keterlibatan perawat dalam pengembangan desain sistem, agar perawat terus menggunakannya untuk meningkatkan mutu dan keselamatan pasien.


2021 ◽  
Vol 17 (1) ◽  
pp. 41
Author(s):  
Yafi Sabila Rosyad ◽  
Setya Retno Wulandari ◽  
Istichomah Istichomah ◽  
Rika Monika ◽  
Anisa Febristi ◽  
...  

AbstrakGenap satu tahun pandemi COVID-19 terjadi dan salah satunya berdampak secara signifikan terhadap kesehatan mental bagi orang tua dan anak, mempengaruhi perubahan fungsi keluarga, dan menimbulkan risiko posttraumatic sindrom. Tujuan penelitian ini adalah untuk mendapatkan gap dan novelty terkait dampak pandemic COVID-19 terhadap kesehatan mental orang tua dan anak. Penelitian ini merupakan penelitian literature review dengan mengunakan diagram alir model PRISMA. Strategi pencarian artikel menggunakan aplikasi publish or perlish. Penelitian ini dilakukan pada bulan 1 Maret- 7 April 2021. Hasil penelusuran artikel melalui aplikasi publish or perlish dengan pencarian melalui tiga database yaitu crossef, google scholar, dan pubmed didapatkan 1216 data yang berupa artikel penelitian, buku, surat untuk editor, dan lembar review artikel. Sedangkan pencarian data melalui registers, peneliti menggunakan register sciencedirect dan didapatkan 339 data yang berupa artikel ilmiah, dan surat untuk editor. Dari ketiga tahap proses pencarian data base didapatkan hasil akhir 15 artikel dari 30 arttikel yang direview. Hasil review metodologi dari 15 artikel didapatkan hasil hampir seluruh artikel menggunakan metode kuantitatif sejumlah 14 artikel dan 1 artikel dengan metode Mixmetod . dari hasil review isi hasil penelitian didapatkan tiga kategori besar berupa perubahan prilaku, perubahan emosi dan psikologis, serta dampak kesehatan. Dari semua artikel yang didapat hampir semunya menggunakan penelitian kuantitatif sehingga peneliti menyarankan kepada peneliti selanjutkan untuk menggunakan metode kualitatif atau mixed metode. Jika ingin menggunakan metode peneliti menyarankan menggunakan design kuasi ekperimen yang bertujuan untuk mengatasi dan mencegah terjadi PTSD. Kata kunci: Stres orang tua, Psikologis anak, Pandemi COVID-19, Mental health AbstractEven one year, the COVID-19 pandemic has occurred. One of them has a significant impact on mental health for parents and children, affects changes in family function, and raises the risk of the posttraumatic syndrome. This study aims to find gaps and novelty related to the impact of the COVID-19 pandemic on the mental health of parents and children. This study is a literature review was conducted on March 1 - April 7, 2021, with the PRISMA model flow chart. The researcher uses a publish or perish application for search article. The search for articles through the publish or perish application by searching through three databases, namely crossref, google scholar, and PubMed, obtained 1216 data in the form of research articles, books, letters to editors, and review sheets article. While searching for data through registers, the researcher used a directly registered record and obtained 339 data in scientific papers and letters to editors. The final results were 15 articles from the 30 articles reviewed from the three stages of the database search process. The methodological review of 15 articles showed that almost all articles used the quantitative method, including 14 articles and 1 article using the Mix method. From the assessment of the contents of the research results, there are three major categories: behavioural changes, emotional and psychological changes, and health impacts. Of all the articles obtained, almost all of them use quantitative research, so researchers suggest that further researchers use qualitative or mixed methods. Researchers recommend using a quasi-experimental design that aims to overcome and prevent PTSD from occurring if you want to use the technique. Keywords: Parental stress, Child psychology, COVID-19 pandemic, Mental health


2021 ◽  
Vol 1 ◽  
pp. 1165-1171
Author(s):  
Sherly Auliasari Harbelubun ◽  
I Irnawati

AbstractA half of teenagers in the world agcd 13-15 year, or around 150 million teenagers, have experienced bullying. This shows that bullying behavior is rampant in adolescence. The impact on victims of bullying such as fear, skipping school, furthermore commit suicide. Meanwhile, a browbeating person often becomes vindictive and violent. The Objectives this study aims to determine the description of bullying in adolescents.The Methods this literature review search results for articles from PubMed, Google scholar found five articles. All articles were appraised by using hawker instruments. The Result this study showed that the average age of reepondents is 14,84 years, primarily females who were victims of bullying (36.9% adolescents), as perpetrators of bullying 19.8% adolescents. Meanwhile, non-victims and perpetrators are as much as 43.3% of adolescents. The type of bullying experienced by victims is verbal bullying (39.3%). Similarly, 39.0% of adolescents are perpetrators of verbal bullying. The Conclusions the victims of bullying are more than those who reported being bullies. The type of bullying in adolescents was mostly verbal bullying.Keywords: Adolescens; bullying; bullies; victims of bullying. AbstrakRemaja di dunia yang berusia 13-15 tahun sebanyak 50% atau setara 150 juta remaja pernah mengalami bullying. Hal ini menunjukan bahwa perilaku bullying sangat tinggi pada usia remaja. Dampak bagi korban bullying seperti ketakutan, tidak ingin sekolah hingga berkeinginan untuk bunuh diri, sedangkan dampak oleh pelaku bullying sering kali pelaku menjadi pendendam, dan berbuat kekerasan. Tujuan penelitian ini bertujuan untuk mengetahui gambaran bullying pada remaja. Metode penelitian ini menggunakan literature review. Hasil pencarian artikel dari PubMed, Google scholar didapatkan 5 artikel. Alat ukur menggunakan instrument hawker. Hasil penelitian ini usia responden rata-rata 14,84 tahun, jenis kelamin paling banyak yaitu perempuan, gambaran korban dan pelaku bullying menjadi korban bullying yaitu 36,9% remaja, sebagai pelaku bullying 19,8% remaja, sedangkan bukan korban dan pelaku sebanyak 43,3% remaja, gambaran jenis bullying pada remaja yaitu bullying yang dialami oleh korban bullying paling banyak adalah bullying verbal yaitu 39,3% remaja, sedangkan jenis bullying yang dilakukan oleh pelaku bullying paling banyak adalah bullying verbal yaitu 39,0% remaja. Simpulan penelitian ini karakteristik responden meliputi usia dan jenis kelamin, yang melaporkan menjadi korban bullying lebih banyak dari yang melaporkan sebagai pelaku bullying, jenis bullying pada remaja sebagian besar bullying adalah bullying verbal.Kata kunci: Remaja; Bullying; Pelaku bullying; Korban bullying


2021 ◽  
Vol 8 ◽  
Author(s):  
Geonildo Rodrigo Disner ◽  
Monica Lopes-Ferreira ◽  
Carla Lima

The aryl hydrocarbon receptor (AhR) is an environmentally responsive ligand-activated transcription factor, identified in the ‘70s for its toxic responses to halogenated polycyclic aromatic hydrocarbons, such as dioxin. Recently, AhR has been recognized as engaged in multiple physiological processes in health and diseases, particularly in the immune system, inflammatory response, tumorigenesis, and cellular differentiation by epigenetic mechanisms involving miRNAs. However, there is still scarce information about AhR-dependent miRNA regulation and miRNA-mediated epigenetic control in pathologies and therapies. In this review, we explore the mutual regulation of AhR and miRNA over the last decade of studies since many miRNAs have dioxin response elements (DRE) in their 3’ UTR, as well as AhR might contain binding sites of miRNAs. TCDD is the most used ligand to investigate the impact of AhR activation, and the immune system is one of the most sensitive of its targets. An association between TCDD-activated AhR and epigenetic mechanisms like post-transcriptional regulation by miRNAs, DNA methylation, or histone modification has already been confirmed. Besides, several studies have shown that AhR-induced miR-212/132 cluster suppresses cancers, attenuates autoimmune diseases, and has an anti-inflammatory role in different immune responses by regulating cytokine levels and immune cells. Together the ever-expanding new AhR roles and the miRNA therapeutics are a prominent segment among biopharmaceuticals. Additionally, AhR-activated miRNAs can serve as valuable biomarkers of diseases, notably cancer progression or suppression and chemical exposure. Once AhR-dependent gene expression may hinge on the ligand, cell type, and context singularity, the reviewed outcomes might help contextualize state of the art and support new trends and emerging opportunities in the field.


2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Henoch W. Burhan ◽  
Yanti M. Mewo ◽  
Youla A. Assa

Abstract: Free radicals are the products of normal cellular metabolism containing one or more unpaired electrons, which makes them highly reactive and can cause cell damage and disruption of homeostasis. Depletion of antioxidants and/or accumulation of free radicals can cause oxidative stress which plays a role in the process of various diseases such as inflammatory diseases, cancer, hemochromatosis, emphysema, hypertension and aging. C-phycocyanin is one of the main groups in phycobiliprotein and widely found in spirulina. The purpose of this study was to determine the protective effect of C-phycocyanin against free radicals. This research is in the form of literature review by searching data using two databases namely Pubmed and Google Scholar. The keywords used are C-Phycocyanin Antioxidant Effect. After being selected based on inclusion and exclusion, 10 literature was obtained for review. C-phycocyanin content in spirulina as an antioxidant can function as a defense mechanism against free radicals. In conclusion: the C-phycocyanin content from spirulina has antioxidant effect.Keywords: C-Phycocyanin, antioxidant effect, free radical   Abstrak: Radikal bebas merupakan produk normal hasil metabolisme berupa molekul dengan satu atau lebih elektron yang tidak berpasangan, sehingga bersifat sangat reaktif dan dapat menyebabkan kerusakan sel dan terganggunya homeostasis. Deplesi dari antioksidan dan/atau akumulasi radikal bebas dapat menyebabkan stres oksidatif yang berperan dalam proses terjadinya berbagai penyakit seperti penyakit inflamasi, kanker, hemokromatosis, emfismea, hipertensi dan proses penuaan. C-fikosianin merupakan salah satu gugus utama dalam fikobiliprotein yang larut dalam air dan banyak terdapat dalam spirulina. Tujuan penelitian ini adalah untuk mengetahui efek proteksi C-fikosianin terhadap radikal bebas. Penelitian ini berbentuk literature review dengan pencarian data menggunakan dua database yaitu Pubmed dan Google Scholar. Kata kunci yang digunakan yaitu C-Phycocyanin Antioxidant Effect. Setelah diseleksi berdasarkan kriteria inklusi dan eksklusi, didapatkan 10 literatur untuk di review. Kandungan C-fikosianin pada spirulina sebagai antioksidan bisa berfungsi sebagai mekanisme pertahanan terhadap radikal bebas. Sebagai simpulan, kandungan C-Fikosianin dalam spirulina memiliki efek antioksidanKata kunci: C-fikosianin, efek antioksidan, radikal bebas


2021 ◽  
Vol 1 ◽  
pp. 217-226
Author(s):  
Kiki Alfiatur Rohmaniah ◽  
Dyah Putri Aryati

Abstract Changes in physical, mental, and sosial function are factors that often lead to psychosocial problems such as depression in the elderly. There is also another factor that causes depression in the elderly is the place of residence. The elderly who lives in care homes are more at risk of experiencing depression. Depression is a common mental health disorder characterized by feelings of depression, guilt, sleep disturbances, decreased appetite, loss of pleasure or interest, feeling less energy, and decreased concentration. The impact of prolonged depression in the elderly can reduce health status, the emergence of self-injury behavior to attempt suicide. To describe the level of depression in the elderly living in care homes. A descriptive study method with a literature review approach. In the search for articles using Google Scholar and the PubMed database. Articles were selected based on the suitability of the specified inclusion and exclusion criteria. There were five articles published in 2011-2020 and using the Geriatric Depression Scale measuring instrument. The critical assessment instrument used is the Joanna Briggs Institute Critical Appraisal. The review result of the five articles showed that there were 112 people (24.2%) who experienced the normal level of depression, 234 people (50.3%) who experienced the mild level of depression, 90 people (19.3%) who experienced the moderate level of depression, and 29 people (6.2%) who experienced the major level of depression. The incidence of depression in the elderly must be addressed immediately, both non-pharmacologically and psychologically so as not to cause effects such as self-injury behavior to attempted suicide.Keywords: elderly; care home; depression level Abstrak Perubahan fungsi fisik, mental dan sosial merupakan faktor yang seringkali mengakibatkan terjadinya permasalahan psikososial salah satunya depresi. Selain dari faktor tersebut ada faktor lain yang menyebabkan depresi pada lansia yaitu tempat tinggal. Lansia yang tinggal di panti sosial lebih beresiko mengalami depresi. Depresi merupakan gangguan kesehatan mental umum yang ditandai dengan perasaan yang tertekan, perasaan bersalah, terjadi gangguan istirahat tidur, nafsu makan menurun, kehilangan kesenangan atau minat, merasa kurang berenergi serta konsentrasi menurun. Dampak dari depresi pada lansia yang berkepanjangan dapat menurunkan status kesehatan, munculnya tingkah laku melukai diri sampai melakukan percobaan bunuh diri. Mengetahui gambaran tingkat depresi pada lansia yang tinggal di panti sosial. Menggunakan metode studi deskriptif dengan pendekatan literature review. Dalam pencarian artikel menggunakan Google Scholar dan database PubMed. Artikel diseleksi berdasarkan kesesuaian kriteria inklusi dan eksklusi yang ditentukan. Didapatkan lima artikel yang dipublikasikan pada tahun 2011-2020 dan menggunakan alat ukur Geriatric Depression Scale. Instrumen telaah kritis yang digunakan adalah Joanna Briggs Institute Critical Appraisal. Hasil review dari kelima artikel lansia dengan kategori normal sebanyak 112 orang (24,2%), depresi ringan sebanyak 234 orang (50,3%), depresi sedang sebanyak 90 orang (19,3%), dan depresi berat sebanyak 29 orang (6,2%). Kejadian depresi pada lansia harus segera diatasi baik secara non farmakologi ataupun psikologis agar tidak memunculkan dampak seperti tingkah laku melukai diri sampai melakukan percobaan bunuh diri.Kata kunci : lansia ; panti sosial ; tingkat depresi


2021 ◽  
Author(s):  
Suhadianto . ◽  
Isrida Yul Arifiana ◽  
Hetti Rahmawati ◽  
Fattah Hanurawan ◽  
Nur Eva

Happiness is the life goal of everyone, including students. But in fact, some student behavior is not in line with the effort to get happiness. Academic Procrastination is one of them. The Covid-19 pandemic, which requires learning to be carried out online, appears to have increased academic procrastination, although there is no definite data about it. This study aims to determine the impact of academic procrastination on Subjective Well-Being. The design of this research is literature review. Researchers conducted a literature search regarding the academic procrastination and subjective well-being through Google Scholar and ScienceDirect. Hermeneutic techniques are used to analyze the literature according to the research objectives. The literature review results show that academic procrastination reduces Subjective Well-Being. The results of this literature review can be a warning to students not to do academic procrastination. Keywords: Academic procrastination; Subjective well-being; Academic Procrastination During Covid-19


e-CliniC ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 402
Author(s):  
Tiffani S. Kairupan ◽  
Natasya T. Rokot ◽  
Hesti Lestari ◽  
Novie H. Rampengan ◽  
Bernabas H. R. Kairupan

Abstrak: Pandemi Coronavirus Disease 2019 (COVID-19) mengakibatkan perubahan yang besar terhadap gaya hidup sehari-hari, termasuk pada anak usia dini. Penelitian ini bertujuan untuk mengetahui dampak lockdown (karantina wilayah) akibat pandemi Covid-19 pada perilaku dan emosi anak usia dini (usia 0-8 tahun), serta kegiatan rutin sehari-hari seperti aktivitas fisik, screen time, dan pola tidur. Penelitian ini merupakan suatu literature review dengan menggunakan database Google Scholar, ScienceDirect, dan PubMed. Terdapat 15 literatur yang dipublikasi dalam bahasa Ingggris atau Indonesiaselang April 2020 dan Maret 2021. Literatur dalam penelitian ini melaporkan tentang perubahan perilaku dan emosi pada anak usia dini. Peningkatan perilaku eksternalisasi dan internalisasi serta perubahan waktu aktivitas fisik dan pola tidur juga dilaporkan pada banyak studi tersebut. Selain itu, terdapat peningkatan screen time selama lockdown. Simpulan penelitian ini ialah lockdown dapat memengaruhi baik pola tidur dan aktivitas fisik maupun kemampuan mengontrol emosi pada anak usia dini.Kata kunci: COVID-19, lockdown, keterbatasan, anak usia dini, perubahan perilaku  Abstract: The coronavirus disease 2019 (COVID-19) pandemic demanded great changes in the everyday lifestyle of people, including children in their early years.This study was aimed toobtain the impact of COVID-19 confinement in young children’s (age 0-8 years) behavior and emotion, along with their daily routines such as physical activity, screen time, and sleep pattern. This was a literature review study using databases of Google Scholar, ScienceDirect, and PubMed. The results showed that there were 15 studies published in English or Indonesian between April 2020 and March 2021 included in this review. The studies reported behavioral and emotional changes in the early life of children. An increase in externalizing and internalizing behavior along with a shift in physical activity and sleep behavior was reported in many of the studies. There was an increase in screen time during lockdown. In conclusion, lockdown can affect not only children’s normal behavior in their sleep and physical activity but also their capability of controlling their emotion.Keywords: COVID-19, lockdown, confinement, early childhood, behavioral changes 


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