scholarly journals Pengaruh Suplementasi Vitamin A pada Pengobatan Pasien TB Paru terhadap Percepatan Konversi Dahak pada Fase Intensif Di Wilayah Kerja Puskesmas Kecamatan Medan Kota

2018 ◽  
Vol 16 (2) ◽  
pp. 124
Author(s):  
Alexander Marpaung ◽  
Parluhutan Siagian ◽  
Dina Keumala Sari
Keyword(s):  
Treatment Group ◽  
Vitamin A ◽  
University Students ◽  
Statistical Testing ◽  
Control Group ◽  
Vitamin A Supplementation ◽  
Intensive Phase ◽  
Pulmonary Tb ◽  
Sputum Conversion ◽  
Conversion Time

Background: Indonesia is in the second rank for the most TB (Tuberculosis) cases in the world after India. It is estimated that there are 1 million cases per year in Indonesia. Objective: The objective of the research was to find out the influence of Vitamin A supplementation in the medication of pulmonary TB on the acceleration of sputum conversion time at intensive phase in the Working Area of Puskesmas in Medan Kota Subdistrict. Methods: This research applied clinical testing design with experimental approach and Experimental Quasi method. The samples were 30 newly diagnosed pulmonary TB patients consisting of15 patients in the treatment group and 15 patients in the control group. They were ³18 years old, regularly consumed category I OAT with BMI ³18.5. The statistical data were analyzed by Mann-Whitney statistical testing at reliability rate 95% (p<0.05).        Result: The results of the research on the treatment group discovered that they were mostly 18-27 years old 40.0%, male 73.3%, mostly university students 26.7%, had BTA conversion in the second week 80.0%; and the sputum conversion time was 2.4 weeks in average. The results of the research on the control group demonstrated that they were mostly 18-27 years old 33.3%, male 80.0%, mostly university students and entrepreneurs 20.0%, had BTA conversion in the second week 80%; and the sputum conversion time was 4.1 weeks in average. Vitamin A supplementation in the medication of pulmonary TB patients had some influence on the acceleration of sputum conversion at intensive phase (p= <0.001) < (alpha = 0.05). Conclusion: Vitamin A supplementation in the medication of pulmonary TB patients had some influence on the acceleration of sputum conversion at intensive phase in the Working Area of Puskesmas in Medan Kota Subdistrict

scholarly journals Vitamin A Supplementation in Pulmonary Tuberculosis Patients on Acceleration of Sputum Conversion in Medan City

2019 ◽  
Vol 7 (20) ◽  
pp. 3505-3508
Author(s):  
Dina Keumala Sari ◽  
Alexander Parlindungan Marpaung ◽  
Parluhutan Siagian ◽  
Nurfida Khairina Arrasyid
Keyword(s):  
Treatment Group ◽  
Vitamin A ◽  
University Students ◽  
Control Group ◽  
Vitamin A Supplementation ◽  
Intensive Phase ◽  
Tuberculosis Patients ◽  
Pulmonary Tb ◽  
Sputum Conversion ◽  
Conversion Time

BACKGROUND: Indonesia is in the second rank for the most TB (Tuberculosis) cases in the world after India. It is estimated that there are 1 million cases per year in Indonesia. AIM: To find out the influence of Vitamin A supplementation in the medication of pulmonary TB on the acceleration of sputum conversion time at an intensive phase in the Working Area of Puskesmas in Medan Kota Subdistrict METHODS: This research was Quasi Experiment method. With two groups. The samples were 30 newly diagnosed pulmonary TB patients consisting of of15 patients in the treatment group and 15 patients in the control group. The statistical data were analysed with t independent test, significance 95% (p < 0.05) RESULTS: The treatment group discovered that they were mostly 18-27 years old 40.0%, male 73.3%, mostly university students 26.7%, had BTA conversion in the second week 80.0%; and the sputum conversion time was 2.4 weeks in average. The results of the research on the control group demonstrated that they were mostly 18-27 years old 33.3%, male 80.0%, mostly university students and entrepreneurs 20.0%, had BTA conversion in the second week 80%; and the sputum conversion time was 4.1 weeks in average. Vitamin A supplementation in the medication of pulmonary TB patients had some influence on the acceleration of sputum conversion at the intensive phase (p ≤ 0.001). CONCLUSION: We concluded that Vitamin A in the medication of pulmonary TB patients had some influence on the acceleration of sputum conversion at the intensive phase in the Medan Kota.

scholarly journals Zinc and vitamin A supplementation fails to reduce sputum conversion time in severely malnourished pulmonary tuberculosis patients in Indonesia

2010 ◽  
Vol 9 (1) ◽  
Author(s):  
Trevino A Pakasi ◽  
Elvina Karyadi ◽  
Ni Made Desy Suratih ◽  
Michael Salean ◽  
Nining Darmawidjaja ◽  
...  
Keyword(s):  
Vitamin A ◽  
Pulmonary Tuberculosis ◽  
Vitamin A Supplementation ◽  
Tuberculosis Patients ◽  
Sputum Conversion ◽  
Conversion Time

scholarly journals Impact of Maternal Daily Oral Low-Dose Vitamin A Supplementation on the Mother–Infant Pair: A Randomised Placebo-Controlled Trial in China

Nutrients ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 2370
Author(s):  
Ye Ding ◽  
Ping Hu ◽  
Yue Yang ◽  
Fangping Xu ◽  
Fang Li ◽  
...  
Keyword(s):  
Health Status ◽  
Breast Milk ◽  
Vitamin A ◽  
Low Dose ◽  
Maternal Serum ◽  
Control Group ◽  
Vitamin A Supplementation ◽  
Maternal Vitamin ◽  
Vitamin A Status ◽  
Lactating Mothers

Background: The nutritional status of vitamin A in lactating mothers and infants is still not optimistic. Due to the dietary habits and dietary restrictions of postpartum customs in China, vitamin A supplementation has been advocated as a potential strategy to improve vitamin A status of lactating mothers with inadequate dietary vitamin A intake. Existing clinical trials are limited to single or double high-dose maternal administrations. However, in China, vitamin A supplements are readily available in the form of daily oral low-dose supplements, and the effect of these is unknown. This study aimed to evaluate the effects of daily oral low-dose vitamin A supplementation on the retinol levels in the serum and breast milk of lactating mothers and the health status of infants in China. Methods: Lactating mothers who met the inclusion criteria and planned to continue exclusive breastfeeding were randomly assigned to receive either daily oral vitamin A and D drops (one soft capsule of 1800 IU vitamin A and 600 IU vitamin D2), or a matching placebo for 2 months. Before and after the intervention, dietary intake was investigated by instant photography, and the retinol concentration in maternal serum and breast milk was determined by ultra-high performance liquid chromatography-tandem mass spectrometry. During the trial, the health status of infants was diagnosed by a paediatrician or reported by lactating mothers. A total of 245 participants completed the study, with 117 in the supplementation group and 128 in the control group. Results: After the 2-month intervention, maternal serum retinol concentrations increased in the supplementation group with no change in the control group. Although breast milk retinol concentrations decreased significantly in both groups, the decrease in the supplementation group was significantly lower than that in the control group. However, maternal vitamin A supplementation was not associated with a lower risk of infant febrile illness, respiratory tract infection, diarrhoea, and eczema. Conclusions: Daily oral low-dose vitamin A supplementation is helpful in improving maternal vitamin A status, despite having no effect on infant health status through breast milk.

scholarly journals The Role of Plant-Based Protein Functional Food in Preventing Acute Respiratory Disease: A Case Study

Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 2116
Author(s):  
Andrei V. Tarasov ◽  
Rofail S. Rakhmanov ◽  
Elena S. Bogomolova ◽  
Ludmila A. Perminova ◽  
Zhanna L. Malakhova
Keyword(s):  
Immune Response ◽  
Treatment Group ◽  
Blood Cell ◽  
University Students ◽  
Blood Serum ◽  
Humoral Immunity ◽  
Functional Food ◽  
Respiratory Diseases ◽  
Protein Product ◽  
Control Group

The Kaliningrad region is known for its specific climate, which can negatively affect the adaptive potential of the body. This manifests in an increased incidence of respiratory diseases and skin conditions. To prevent high morbidity, a plant protein product was included in the diet of first-year university students. This study aimed to assess the effectiveness of this food intervention in preventing the most common diseases among Kaliningrad students. Two groups of university students took part in the food trial. In the control group, catabolic processes prevailed in nutrient metabolism. Disadaptation manifested itself in the metabolism of proteins, vitamins, minerals, hematopoiesis and humoral immunity. Inflammation was indicated by α1- and α2-globulins, a weak immune response, and IgM and IgG. High oxidative stress and low antioxidative ability of blood serum were observed. The plant-based protein product (FP) helped preserve testosterone level and prevent an increase in catabolic reactions. Moreover, it had a positive effect on both red blood cell hematopoiesis (a smaller increase in the average volume of erythrocytes, the same average concentration and content of hemoglobin, an increased relative red cell distribution width (RDW) and white blood cell hematopoiesis (a beneficial effect for the immune system: lymphocytes, the relative content of neutrophils, monocytes, basophils and eosinophils). The stimulation of humoral immunity was evidenced by beta- and gamma-globulins, an active immune response, the level of IgM and IgG, antioxidant protection, reduction of peroxides and an increase in antioxidant activity of blood serum. The 34-week observation showed a 1.7-fold decrease in the incidence of respiratory illnesses and a 5.7-fold decrease in skin and subcutaneous tissue diseases. Acute respiratory infections were reduced 1.8-fold. There were no cases of community-acquired pneumonia in the treatment group, compared with 55.1‰ in the control group. The incidence of respiratory diseases was 3.3–10.6 times lower in the treatment group than in the control group in weeks 6–19. The findings testify to the prophylactic effect of functional food during social adaptation and acclimatization of students.

Effects of recasts and form-focused instruction on the acquisition of novel vocabulary

2019 ◽  
Vol 10 (4) ◽  
pp. 603-624
Author(s):  
Yingli Yang ◽  
Lawrence Jun Zhang ◽  
Ling Chen
Keyword(s):  
Working Memory ◽  
Treatment Group ◽  
University Students ◽  
Vocabulary Development ◽  
Mediating Effect ◽  
Effect Sizes ◽  
Superior Performance ◽  
Control Group ◽  
Reading Span ◽  
Group A

AbstractThe present study explores the effects of recast plus form-focused instruction and form-focused instruction on vocabulary development and the mediating effect of working memory. Sixty-six university students were assigned to a recast plus form-focused instruction (FFI) group, a FFI group, and a control group. The instructor provided recasts on non-target vocabulary items in the recast plus FFI group, whereas the FFI group completed two form-focused vocabulary tasks only. Pretests, posttests, and delayed posttests were administered to examine learners’ development of target vocabulary items. A reading span test was employed to examine learners’ complex working memory capacities. Results show that the recast plus FFI group exhibited superior performance over the control group on both posttests and delayed posttests with large effect sizes. Working memory did not significantly correlate with vocabulary development in either treatment group.

Blood Profile of Vitamin A and β-Carotene During Post-Partum Period in Surti Goats

2017 ◽  
Vol 12 (3) ◽  
Author(s):  
Sandhya S. Chaudhary ◽  
Tanvi D. Manat ◽  
Virendra Kumar Singh ◽  
Sanjay B. Patel
Keyword(s):  
Treatment Group ◽  
Vitamin A ◽  
Post Partum ◽  
Control Group ◽  
Blood Collection ◽  
Blood Profile ◽  
Significant Difference ◽  
Post Partum Period ◽  
Β Carotene

The present study was undertaken to study levels of vitamin A and β-carotene in blood of postpartum Surti goats. 40 Surti goats were selected comprising of 20 goats with recent parturition (treatment group) and 20 non-pregnant animals (control group). Blood collection was done on 0, 7, 14, 21, 30 and 45 day post-kidding (treatment group) and once from control group and analyzed for Vitamin A and β-carotene. Both the analytes were significantly low on 0 day. Significant difference (P Less Than 0.05) in vitamin A as well as β-carotene (P Less Than 0.01) was observed between 0 and 21st day postpartum followed by non-significant difference in vitamin A after 21 days. However, β-carotene values at 21st day significantly differed from those at 30th and 45th day. Non–significant difference between control and treatment group from 7th day onwards was observed in vitamin A. β-carotene values of treatment group were significantly lower at 0 and 21st day postpartum as compared to control. It was concluded that on the day of kidding there is decrease in circulatory levels of vitamin A and β-carotene and this decrease can be used as an indicator of stress.

scholarly journals Providing mothers with mobile phone message reminders increases childhood immunisation and vitamin A supplementation coverage in Côte d’Ivoire: a randomised controlled trial

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Romance Dissieka ◽  
Marissa Soohoo ◽  
Amynah Janmohamed ◽  
David Doledec
Keyword(s):  
Randomised Controlled Trial ◽  
Vitamin A ◽  
Mobile Phone ◽  
Cote D'ivoire ◽  
Controlled Trial ◽  
Intervention Group ◽  
Control Group ◽  
Vitamin A Supplementation ◽  
Randomised Controlled ◽  
To Receive

We conducted a randomised controlled trial to assess the effect of providing mothers with mobile voice or text (SMS) reminder messages on health facility attendance at five infant immunisation and vitamin A supplementation (VAS) visits. The study was conducted at 29 health facilities in Korhogo district. Mothers were randomised to receive a voice or text reminder message two days prior to each scheduled visit and two additional reminders for missed doses (n = 798; intervention group), or no phone reminder messages (n = 798; control group). Infants in the intervention group were 2.85 (95% CI: 1.85-4.37), 2.80 (95% CI: 1.88-4.17), 2.68 (95% CI: 1.84- 3.91), and 4.52 (95% CI: 2.84-7.20) times more likely to receive pentavalent 1-3 and MMR/yellow fever doses, respectively, and 5.67 (95% CI: 3.48-9.23) times more likely to receive VAS, as compared to the control group. In the reminder group, 58.3% of infants completed all five visits, compared to 35.7% in the control group (P < 0.001). Providing mothers mobile phone message reminders is a potentially effective strategy for improving immunisation and VAS coverage in Côte d’Ivoire.

scholarly journals Analysis of the intermediate results of the INVENT-1 clinical trial: open-label, randomized, multicenter study

2020 ◽  
pp. 78-79
Author(s):  
O.S. Denysov
Keyword(s):  
Treatment Group ◽  
Oral Administration ◽  
Oral Therapy ◽  
Therapy Group ◽  
Oral Treatment ◽  
Long Term Results ◽  
Intensive Phase ◽  
Pulmonary Tb ◽  
Infusion Group ◽  
Intravenous And Oral Administration

Background. Attempts to treat tuberculosis (TB) with the help of intravenous drugs have been made since the early XX century. However, XXI century medicine recommends treating TB with pills, and invasive anti-TB drugs (ATBD) are rarely used. International expert groups recommend intravenous administration only for critically ill patients or for patients with absorption disorders. Meanwhile, the advantages of intravenous ATBD include direct monitoring of treatment, accurate dosing for each patient, fewer side effects, and avoidance of taking a large number of tablets. Objective. To evaluate the efficacy, safety, and tolerability of intravenous and oral administration of ATBD in the intensive phase of treatment in patients with advanced destructive pulmonary TB with bacterial excretion. Materials and methods. The study involved 318 patients from 9 clinical centres. The total duration of the study was 18 months. Intravenous and oral administration of isoniazid, rifampicin and ethambutol were compared. The intensive phase of the study lasted 2 months, the maintenance phase lasted 4 months. Inclusion criteria were the following: age 18-65 years, diagnosis of pulmonary TB, at least one positive test result for TB mycobacteria, radiological confirmation of lung destruction and advance TB process, in women – negative urine test for pregnancy, informed consent, negative GenXpert MTB/RIF analysis, and verbal consent to abstain from alcohol during the study. Results and discussion. Due to the resistance to 1st line drugs 14 people were excluded from the study, due to the lack of data on culture – 16 people, for other reasons – 7 people. In the infusion treatment group, 52.63 % had disseminated TB, and 47.37 % had infiltrative TB. In the group of tablet treatment disseminated TB occurred in 35.2 % of patients, infiltrative – in 61.8 %, miliary – in 3 %. At 4th visit, the efficacy of abacillation in both treatment groups was comparable: 34.2 % in the infusion group and 35.26 % in the oral treatment group. But as of the 6th visit, the share of abacillation in the infusion group was 57.42 %, and in the oral treatment group – 46.96 %. Analysis of the time needed to achieve a negative result on mycobacterium TB also revealed the benefits of infusions. Thus, up to the 3rd visit this parameter was reached by 15.78 % of the infusion group patients, and by 13.76 % of oral therapy group patients. The total proportion of patients with a negative test for mycobacterium TB and clinical improvement in the infusion group was 60 %, and in the oral therapy group – 52.90 %. In infiltrative TB, 27.8 % of the infusion group and only 9.5 % of the tablet therapy group reached abacillation by the 3rd visit. In disseminated TB, abacillation was achieved up to 3rd visit in 5 % of the infusion group and 8.3 % of the tablet treatment group, however, the total numbers at the end of the study were 45 and 25 %, respectively. Conclusions. 1. Monitoring the patient’s treatment is a cornerstone of TB therapy. 2. There is a tendency to the greater effectiveness of TB treatment using intravenous ATBD in the intensive phase of therapy. 3. It is necessary to analyze the long-term results of treatment and the impact of both treatment regimens on the recurrence of the process.

scholarly journals The Impact of Emotional Intelligence towards Political Behaviour among University Students

2018 ◽  
Vol 7 (4.1) ◽  
pp. 67
Author(s):  
Siti Sarawati Johar ◽  
Sazuliana Sanif ◽  
Fauziah Ani ◽  
Harliana Halim ◽  
Shahidah Hamzah ◽  
...  
Keyword(s):  
Emotional Intelligence ◽  
Treatment Group ◽  
University Students ◽  
The Political ◽  
Control Group ◽  
Test Analysis ◽  
Political Behaviour ◽  
Post Test ◽  
The Difference ◽  
The Impact

In this experimental study, the issue is focused on the influence of emotional intelligence in shaping the political behaviour of university youth students. The specific objective of this study is to examine the impacts of emotional intelligence competency on political behaviour among youth at the university by looking at the significance difference in the treatment group and the control group through application of emotional intelligence module. A total of 608 university students were selected as respondents from four public universities in Malaysia. The measuring tools used were the Emotional Intelligence Self-Description Inventory (EISDI), and the Political Behaviour Questionnaire (PBQ). In this study, T-test analysis and ANOVA test were used to determine the difference between the two control and treatment groups. The findings showed that there was a significant impact on the post-test for the treatment group due to the pre-and post-treatment differences. However, the findings from the control group showed no significant value. In addition, the findings show that the treatment group has the impact of changing the political behaviour with the implementation of emotional intelligence competencies in the teaching modules. The findings of this study provided sharing of the importance of the implementation of emotional intelligence among university students to form positive behaviours in political aspects. 

scholarly journals Clinical benefits of vitamin A supplementation in infants and children with severe pneumonia

2007 ◽  
Vol 47 (3) ◽  
pp. 120
Author(s):  
Prisca T. ◽  
J. S. Lisal ◽  
Azis Tanra ◽  
Dasril Daud
Keyword(s):  
Vitamin A ◽  
Respiratory Rate ◽  
Vitamin A Deficiency ◽  
Severe Pneumonia ◽  
Acute Respiratory Tract Infection ◽  
Control Group ◽  
Vitamin A Supplementation ◽  
Systemic Complications ◽  
Significant Difference ◽  
Clinical Benefits

Background About 190 million preschool children living indeveloping countries are at risk of vitamin A deficiency. VitaminA deficiency and acute respiratory tract infection (ARI) are publichealth problems in developing countries. Children with vitaminA deficiency are more susceptible to measles, respiratory tractinfection, and other infections. Some studies show that vitaminA supplements may reduce the severity of respiratory tractinfection and other systemic complications of measles, anddiarrhea.Objective To evaluate the effect of vitamin A supplementation ininfants and children with severe pneumonia.Methods The study was a randomized trial on children with severepneumonia. Participants were randomly assigned to either receivevitamin A in addition to standard treatment (Group A), orstandard treatment alone (Group C). Time to achieve the normalrespiratory rate, time to achieve disappearance of subcostalretractions and fine rales were compared between the 2 groups.Result There was no significant difference in the achievement ofnormal respiratory rate between the vitamin group and the controlgroup (3.08 days vs 3.29 days). There was also no significantdifference in the disappearance of subcostal retractions amongthe two groups (2.30 days vs 2.48 days). However, there wassignificant difference in the disappearance of fine rales betweenthe two groups. The disappearance of fine rales in the vitamin Agroup occurred earlier (mean 3.72 days) than in the control group(mean 4.04 days) (P<0.01).Conclusions This study indicates that no significant difference inthe achievement of normal respiratory rate and disappearance ofsubcostal retractions between the vitamin A group as comparedto the control group, but there was a significant difference in thedisappearance of fine rales between two groups.

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