scholarly journals EFFECTIVENESS OF PROBIOTICS AS AN ADJUNCT IN PERIODONTAL CARE

2021 ◽  
Vol 31 (2) ◽  
pp. 226-231
Author(s):  
Jurgita Vazgytė ◽  
Ieva Vaškelytė ◽  
Urtė Marija Sakalauskaitė
Keyword(s):  
Literature Review ◽  
Periodontal Diseases ◽  
Control Group ◽  
Inclusion Criteria ◽  
Immunological Parameters ◽  
Prisma Statement ◽  
Bacterial Recolonization ◽  
Root Planning ◽  
Scaling And Root Planning ◽  
Selection Of

Relevance of the problem. Periodontitis is a multifactorial inflammatory disease related with dysbiotic plaque biofilms and characterized by progressive destruction of the tooth-supporting apparatus. Treatment of periodontitis aims to prevent further disease progression, to minimize symptoms and perception of the disease, possibly to restore lost tissues and to support patients in maintaining a healthy periodontium. Scaling and root planning (SRP) is the gold standard for the treatment of periodontitis. For the reduction in bacterial recolonization probiotics have been suggested as promising agents not only to retard recolonization, but also to increase the number of beneficial bacteria and to modulate immunological parameters in the prevention and treatment of periodontal disease. Aim of the work. To find out and assess the data of clinical trials that proposes clinical outcomes of the adjunctive use of probiotic for 3 months after SRP in comparison to SRP combined with a placebo. Tasks: 1) ascertain and assess the recolonization of bacteria after active treatment of periodontitis; 2) clarify and evaluate clinical variables improvement after the usage of local adjunctives; 3) find out and assess the distinction between different probiotics strains. Material and methods. This literature review has been carried out in accordance with the PRISMA Statement [23]. Electronic literature review was performed using MEDLINE and ELSEVIER databases and the selection of the articles, published in English between 2010 and 2020 year. The search for publications was based on keywords and their combinations: chronic periodontitis, scaling and root planning, adjunct care, probiotics, supplements. Results. This literature review includes eight suitable studies that met the inclusion criteria. Conclusions. The qualitative findings of the studies showed that major part of the included trials reported significant improvement in clinical periodontal parameters in periodontitis patients with the adjunctive use of probiotics compared with control group. 75 % of included studies made with L. reuteri found probiotic containing L. reuteri usage as an adjunct therapy to be significant in the improvement of clinical parameters. Probiotic therapy could be used for managing periodontal diseases. This review puts a stress on L. reuteri effectiveness. However, further studies are needed to substantiate its longitudinal effect.

scholarly journals The Effects of Salvia officinalis Gel as an Adjunct to Scaling and Root Planning in Patients with Periodontitis (Clinical and Immunological Study)

2020 ◽  
Vol 10 (02) ◽  
pp. 232-237
Author(s):  
Ismael W. Aljuboori ◽  
Maha Sh. Mahmood
Keyword(s):  
Transforming Growth Factor Beta ◽  
Chronic Periodontitis ◽  
Transforming Growth Factor ◽  
Gingival Crevicular Fluid ◽  
Test Group ◽  
Control Group ◽  
Growth Factor Beta ◽  
Crevicular Fluid ◽  
Root Planning ◽  
Scaling And Root Planning

Background: Phytotherapy is the usage of herbal species with medicinal properties for the management of various diseases. Gingivitis and periodontitis are diseases that involve the role of both the bacteria and the host immune response. Over the years, various researches have shown the importance of herbal products in the management of periodontal diseases. Aims of the study: To evaluate the efficacy of locally applied Salvia officinalis gel as adjunctive in the treatment of chronic periodontitis. Subjects and methods: Fourteen patients (10 males and 4 females) with chronic periodontitis were enrolled in the present study with total number of twenty-eight periodontal pockets utilizing a split mouth design, the pockets were divided into two groups, the test group which was treated with scaling and root planning procedure and the application of the S. officinalis gel, and the control group that treated with scaling and root planning only. Plaque index (PI) and gingival index (GI) were recorded for each site. Gingival crevicular fluid (GCF) was collected from each site by using PerioCol paper strips. The concentration of the transforming growth factor beta-1 in the gingival crevicular fluid was quantified by a high sensitivity enzyme-linked immunosorbent assay. Results: The test group demonstrated a significant reduction in GI at 1-week and 1-month after the treatment comparing to baseline (1.14 vs. 1.64, p = 0.003, and 1.21 vs. 1.64, p = 0.028, respectively), while no significant reduction in the PI at recall visits comparing to baseline. The control group demonstrated no significant reduction in PI and GI at recall visits, comparing to baseline. Both the test and control groups demonstrated no significant reduction in the transforming growth factor-beta 1 concentration in the gingival crevicular fluid at one week after the treatment comparing to baseline, while at one month after the treatment only the test group demonstrated a significant reduction comparing to baseline (3.91 vs. 9.62, p = 0.044). Conclusion: The findings of the present study indicated that the S. officinalis gel has a potential anti-inflammatory role in the treatment of chronic periodontitis by monitoring both the clinical and immunological parameters.

scholarly journals Clinical evaluation of ultrasonic subgingival debridement and ultrasonic subgingival scaling combined with manual root planning in patients with periodontitis: study protocol for a randomized controlled trial

2019 ◽  
Author(s):  
Yue Yan ◽  
Yalin Zhan ◽  
Xian'e Wang ◽  
Jianxia Hou
Keyword(s):  
Periodontal Diseases ◽  
Controlled Trial ◽  
Test Group ◽  
Periodontal Therapy ◽  
University Hospital ◽  
Control Group ◽  
Root Planing ◽  
Patient Reported ◽  
Subgingival Scaling ◽  
Root Planning

Abstract Background: Periodontal diseases are regarded as the most common diseases of mankind. The prevalence rate of periodontal disease assumes the obvious growth tendency in the whole world, increased by 57.3% from 1990 to 2010. Thereby, effective periodontal therapy is still a long-term task and tricky problem. The goals of periodontal therapy are to eliminate the infectious and inflammatory processes. Root planning, in order to eliminate the “infected cementum”, is an important step in treatment of periodontitis since 1970s. Along with the understanding of endotoxin’s feature on root surface, the necessity of manual root planing has been gradually queried. Ultrasonic instruments wouldn’t remove the cementum excessively, which are more time-saving and labor-saving compared to hand instruments as well. Hence, an increasing number of dentists prefer to scaling with ultrasonic instruments only. However, the necessity of root planing has still been emphasized in the international mainstream views of periodontal mechanical treatment. Therefore, this study is devoted to compare the clinical effect of ultrasonic subgingival debridement and ultrasonic subgingival scaling combined with manual root planing, which taking the implementation of root planing as the only variable and more in line with the clinical situation, hoping to provide some reference to dentists. Methods/design: Forty adult patients who fit the inclusion criteria are being recruited from the Peking University Hospital of Stomatology (Beijing, China). By means of randomization tables, one quadrant of the upper and lower teeth is the test group and the other is the control group. Test group: ultrasonic subgingival scaling combined with manual root planing. Control group: ultrasonic subgingival debridement. In a 24-weeks follow-up period, plaque index, probing depth, clinical attachment loss, bleeding index, furcation involvement, mobility, and patient-reported outcome (visual analog scale for pain and sensitivity) will be observed and documented. Discussion: This study evaluates the effectiveness of ultrasonic subgingival scaling combined with manual root planing and ultrasonic subgingival debridement alone in nonsurgical treatment of periodontitis with a split-mouth design after 1, 3 and 6 months. The result of the trial will potentially contribute to an advanced treatment strategy of periodontitis with ideal clinical outcome. Trial registration: The study has been registered in International Clinical Trials Registry Platform (ICTRP) under the identifier number ChiCTR1800017122. Registered on 12 July 2018. Keywords: Peridontitis, Non-surgical periodontal therapy, Ultrasonic subgingival debridement, Root planing

scholarly journals Analisis Analisis Strategi Coping Stres pada Ibu Single Parent Setelah Ditinggal Suami: Literatur Sistematik Review

2021 ◽  
Vol 3 (3) ◽  
pp. 1378-1388
Author(s):  
Dulce Elda Ximenes Dos Reis ◽  
Endang Retno Surjaningrum ◽  
Ike Herdiana
Keyword(s):  
Literature Review ◽  
Coping Strategies ◽  
Quantitative Research ◽  
Psychological Needs ◽  
Single Parent ◽  
Inclusion Criteria ◽  
Dual Roles ◽  
Stress Coping Strategies ◽  
Instrumental Action ◽  
Selection Of

The purpose of this literature is to determine the selection of stress coping strategies used by single parent mothers in dealing with problems after the abandonment of their husbands. The method used in writing this literature review is to search for literatures using databases such as http://garuda.ristekbrin.go.id/ and Google Scholar. The results of this literature review identified five articles that met the inclusion criteria. From the literature obtained, the majority use this type of qualitative research as many as 3 articles and 2 articles using quantitative research. Several studies have shown that the most effective and often used strategies for single parent mothers after their husband leave behind are problem focused coping and emotion focused coping.The conclusion of the study shows that the situations that cause stress to the three single parent mothers after the abandonment of their husbands are (a) the dual roles that are played after the husband leaves, namely meeting the psychological needs of the child, (b) work, (c) accusations from neighbors and (d) economic problems. The coping strategies used by single parents after their husband left their husbands are emotional focused coping (coping that focuses on emotions) and problem focused coping (coping that focuses on problems). Emotional focused coping that is used is avoiding problems, ignoring problems, blaming yourself and interpreting problems. Meanwhile, the problem focused coping used is exercised caution, instrumental action and negotiation.

scholarly journals Kawasaki and COVID-19 disease in children: a systematic review

2020 ◽  
Vol 66 (suppl 2) ◽  
pp. 136-142
Author(s):  
Laura Faustino Gonçalves ◽  
Ana Inês Gonzales ◽  
Fernanda Soares Aurélio Patatt ◽  
Karina Mary de Paiva ◽  
Patrícia Haas
Keyword(s):  
Systematic Review ◽  
Kawasaki Disease ◽  
Literature Review ◽  
Scientific Evidence ◽  
Severe Form ◽  
Evidence Based ◽  
Inclusion Criteria ◽  
Medical Subject Heading ◽  
High Incidence ◽  
Selection Of

SUMMARY OBJECTIVE To present scientific evidence based on a systematic literature review (PRISMA) evaluating the association of Kawasaki Disease (DK) and COVID-19 in children. METHODS For the selection of studies, a combination based on the Medical Subject Heading Terms (MeSH) was used. The Medline (Pubmed), LILACS, SciELO, COCHRANE, and BIREME databases were used. The search period for the articles comprised the last 10 years (2010 to 2020). RESULTS 840 articles with potential for inclusion were retrieved, one of which met the inclusion criteria and the guiding question that consisted of evaluating the association of Kawasaki disease and COVID-19 in children. CONCLUSION A significant increase in the incidence of Kawasaki-type diseases after the onset of the epidemic has been reported, suggesting an association between the COVID-19 epidemic and the high incidence of a severe form of KD. However, further studies are needed to conduct an investigation of the association between these two diseases.

scholarly journals The Effect of Scaling and Root Planning on Salivary TNF-α and IL-1α Concentrations in Patients with Chronic Periodontitis

2017 ◽  
Vol 11 (1) ◽  
pp. 573-580 ◽  
Author(s):  
Masoome Eivazi ◽  
Negar Falahi ◽  
Nastaran Eivazi ◽  
Mohammad Ali Eivazi ◽  
Asad Vaisi Raygani ◽  
...  
Keyword(s):  
Chronic Periodontitis ◽  
Interleukin 1 ◽  
Negative Relationship ◽  
Inflammatory Factors ◽  
Control Group ◽  
Pocket Depth ◽  
Necrosis Factor Alpha ◽  
Tnf Α ◽  
Root Planning ◽  
Scaling And Root Planning

Objective:Periodontitis is one of the main diseases in the oral cavity that causes tooth loss. The host immune response and inflammatory factors have important role in periodontal tissue. The current study was done with the objective to determine the effect of scaling and root planning on the salivary concentrations of tumor necrosis factor-alpha (TNF-α) and interleukin-1-alpha (IL-1α).Methods:In this quasi-experimental clinical trial, 29 patients with chronic periodontitis and 29 healthy subjects without periodontitis were studied. Clinical examination findings and salivary TNF-α and IL-1α (using ELISA method) were compared before and after scaling, root planning.Results:Before starting treatment, salivary TNF-α and IL-1α concentrations were higher in healthy control group than in periodontitis group (P< 0.05). Non-surgical treatment increased the concentration of these two biomarkers in the saliva. However, increase in IL-1α concentration was not statistically significant (P= 0.056). There was a negative relationship between TNF-α and IL-1α levels with pocket depth and attachment loss (P< 0.05).Conclusion:Scaling and root planning improved periodontal disease indices and salivary TNF-α and IL-1α levels.

Evaluation of the Clinical and Immunological Parameters During Treatment Chronic Periodontitis by Camelyn Mouthwash

2017 ◽  
Vol 13 (15) ◽  
pp. 1
Author(s):  
Irma Kachkachishvili ◽  
Boris Korsantia ◽  
Mzia Bakradze ◽  
Lali Aladashvili ◽  
Iamze Taboridze
Keyword(s):  
Positive Influence ◽  
Dental Clinic ◽  
T Suppressors ◽  
Immunological Parameters ◽  
Traditional Treatment ◽  
Immunological Effects ◽  
Is Evaluation ◽  
Cellular And Humoral Immunity ◽  
Root Planning ◽  
Scaling And Root Planning

The purpose of study is Evaluation of Clinical and Immunological effects of using Camelyn in Periodontology. Materials and methods: We have studied clinical and immunological features of 20 patients with periodontitis between ages 20 and 60 (these patients were from the dental clinic Mitra). CPI index has been studied dynamically — before treatment, after treatment, 6 months and 1 year later. Treatment included scaling and root planning. During these 2 weeks we have used 10 ml of Camelyn 25 percent solution for rinsing. We applied it for 2 minutes. We checked cellular and humoral immunity in peripheral blood stem. Lysozyme activation was determined. Results: After treatment, the median CPI index was significantly reduced. After 6 months and a year of treatment it was insignificantly increased, but in comparison with the initial CPI it was remained significantly less.Before starting treatment Interferon and the phagocytic system was significantly lowered, also amount of TLymphocytes, but the amount of T suppressors was increased; After the treatment mentioned above the parameters were significantly increased, although in comparison with the standard it still was low. After the treatment the amount of T- suppressors was significantly decreased.Saliva significantly showed a reduction of the amount of lysozyme and sIgA Before treatment IgG was significantly lower and IgM higher. After the treatment all kinds of Immunoglobulins were almost the same; Conclusion: Including Camelyn in traditional treatment of periodontitis promotes immune response activation and it has a positive influence on a clinical picture —it improves periodontitis clinical features and significantly reduces CPI index.

scholarly journals Formulation and Evaluation of a New Biodegradable Periodontal Chip Containing Thymoquinone in a Chitosan Base for the Management of Chronic Periodontitis

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Fouad H. Al-Bayaty ◽  
Azwin A. Kamaruddin ◽  
Mohd. A. Ismail ◽  
Mahmood A. Abdulla
Keyword(s):  
Chronic Periodontitis ◽  
Statistical Significance ◽  
Plaque Index ◽  
Control Group ◽  
Paired Sample ◽  
Chi Squared ◽  
Periodontal Probing ◽  
Root Planning ◽  
One Way Anova ◽  
Scaling And Root Planning

Objective.This study was performed to develop a biodegradable periodontal chip containing thymoquinone and to evaluate its effectiveness for managing chronic periodontitis.Methods.Chips were formulated from thymoquinone and chitosan. Twelve patients with periodontal pockets measuring ≥5 mm participated in this study. Overall, 180 periodontal pockets were evaluated. At day zero, all patients were treated with full-mouth scaling and root planning. Periodontal pockets were divided into three groups. Group one served as the control group, while group two received plain chitosan chips. Group three received chips containing thymoquinone. Plaque index, bleeding upon probing, periodontal probing pocket depths, and clinical attachment levels were recorded at days 0 and 60.Results.The statistical significance of differences was tested with a paired samplet-test, a Chi-squared test, and a one-way ANOVA. The results indicated significant improvement in plaque index and bleeding upon probing and a reduction in periodontal pockets from baseline in all four groups(P<0.05). Gains in clinical attachment levels were significantly higher(P<0.005)in the group receiving thymoquinone chips compared to other groups.Conclusion.Periodontal chips containing thymoquinone can be used as adjuncts for the treatment of patients with chronic periodontitis.

scholarly journals Therapeutic strategies in the treatment of periodontitis

2012 ◽  
Vol 58 ◽  
pp. 3-14 ◽  
Author(s):  
Liljana Bogdanovska ◽  
Silvana Kukeska ◽  
Mirjana Popovska ◽  
Rumenka Petkovska ◽  
Katerina Goracinova
Keyword(s):  
Standard Treatment ◽  
Alveolar Bone ◽  
Periodontal Diseases ◽  
Therapeutic Agents ◽  
Scaling And Root Planing ◽  
Periodontal Pathogens ◽  
Beneficial Effects ◽  
Root Planning ◽  
Supporting Structures ◽  
Scaling And Root Planning

Periodontitis is a chronic inflammatory process which affects the tooth - supporting structures of the teeth. The disease is initiated by subgingival periopathogenic bacteria in susceptible periodontal sites. The host immune response towards periodontal pathogens helps to sustain periodontal disease and eventual alveolar bone loss. Although scaling and root planing is the standard treatment modality for periodontitis, it suffers from several drawbacks such as the inability to reach the base of deep pockets and doesn’t arrest migration of periodontal pathogens from other sites in the oral cavity. In order to overcome the limitations of scaling and root planning, adjunctive chemotherapeutics and host modulatory agents to the treatment are used. These therapeutic agents show substantial beneficial effects when compared to scaling and root planning alone. This review will cover an update on chemotherapeutic and past and future host immune modulatory agents used adjunctively to treat and manage periodontal diseases.

Comparative analysis of polymorphic variants of IL-17A and MMP-1 genes with the risk of developing chronic periodontitis in petrochemical workers

2020 ◽  
Vol 60 (10) ◽  
pp. 687-693
Author(s):  
Iskander I. Zaidullin ◽  
Denis O. Karimov ◽  
Lilija K. Karimova ◽  
Milyausha F. Kabirova ◽  
Rasima R. Galimova ◽  
...  
Keyword(s):  
Ethylene Oxide ◽  
Chronic Periodontitis ◽  
Periodontal Diseases ◽  
Clinical Manifestations ◽  
Control Group ◽  
Periodontal Tissues ◽  
Dental Examination ◽  
Number Of Patients ◽  
Increased Risk ◽  
Harmful Substances

The susceptibility to the development and progression of inflammatory periodontal diseases, which depends on genetic and external factors (smoking, stress, oral hygiene), varies widely. In the development of these diseases, an important role is played not only by the presence of periodontal pathogenic microorganisms, but also by the presence of congenital or acquired immunodeficiency, immunoregulatory defects. The immune system plays a key role in the physiological and pathological processes of periodontal tissues. In this regard, IL17, produced by CD4+ Th cells, which has both Pro-inflammatory and protective activity, is of particular interest in the pathogenesis of periodontitis. The aim of study was to identify the relationship between polymorphic loci of the IL-17A (rs2275913) and MMP-1 (rs1799750) genes and clinical manifestations of chronic periodontitis in petrochemical workers. Dental examination was performed in 92 ethylene oxide production workers with chronic periodontitis and 74 patients with chronic periodontitis who did not come into contact with chemical factors (control group). Genotyping of polymorphisms rs2275913 of the IL17A gene and rs1799750 of the MMP1 gene was performed by allele-specific real-time polymerase chain reaction (PCR). Hygienic assessment of the degree of air pollution of the working area with harmful substances was carried out by gas chromatography according to the guidelines for the determination of harmful substances in the air № 5098-89, № 3119-84. When comparing the results of studies of both groups, there were no statistically significant differences in the frequency distributions of allelic variants and genotypes of the IL-17A and MMP-1 genes. The AA/AG genotypes of the IL-17A gene were associated with an increased risk of severe disease compared to the GG genotype in workers in the main group (OR=6.1; 95% CI 1.33-28.5; p=0.021) and in the control group (OR=7.26; 95% CI 1.34-39.25; p=0.016). Carriers of the A allele in the control group increased the risk of severe chronic periodontitis by 2.4 times compared to carriers of the G allele (OR=2.41; 95% CI 1.19-4.87; p=0.014). During the dental examination of employees of the ethylene oxide plant, the clinical course of periodontal diseases was more severe in comparison with the control group, and the number of patients with severe periodontitis was twice as high. It was found that the AA/AG genotypes of the IL-17A gene and the carrier of the A allele are associated with increased susceptibility to the development of severe chronic periodontitis. The association between the MMP-1 gene polymorphism and the risk of severe forms of chronic periodontitis has not been established. A risk factor for the development of inflammatory periodontal diseases in employees of the petrochemical complex is a complex of harmful production factors.

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