A STUDY OF CORRELATION OF PRAGMATIC RISK SCORE WITH MORTALITY IN PATIENTS ADMITTED TO RLJH AND RC ICU WITH CORONAVIRUS DISEASE 2019 (COVID-19)

2021 ◽  
pp. 3-5
Author(s):  
K. Hemanth kumar reddy ◽  
Prabhakar K ◽  
Pavan Pavan
Keyword(s):  
Risk Score ◽  
Prognostic Score ◽  
Severe Illness ◽  
P Value ◽  
Age Group ◽  
Rt Pcr ◽  
Medical College ◽  
Survival Percentage ◽  
Considerable Portion ◽  
Objective Study

Background : In many people the disease is mild and self-limiting, but in a considerable portion of patients the disease is severe and fatal. Determining which patients are at high risk of severe illness or mortality is an essential part of understanding this illness Aims and Objective : Study of correlation of prognostic risk score with mortality in patients admitted to RLJH and RC ICU with coronavirus disease 2019 (COVID-19) . Methodology : This was a Retrospective observational study in the patients tested RT-PCR positive for COVID 19 and admitted at SRI DEVARAJ URS MEDICAL COLLEGE Tamaka, Kolar during the two month duration i.e. June 2021 to July 2021 in the 50 patients .The statistical analysis was done by Graph pad prism 6 version from that we have calculated correlation co-efcient and Survival graph Result : In our study we have seen that The majority of the patients were in the age group of 61-70 were 28% , followed by 51-60 were 24%, 71-80 were 22%, 41-50 were 14% , 30-40 & >80 were 6%. The majority of the patients were Male i.e. 68% and Female were 32%. There was strong correlation between Prognostic score and mortality of the patients which was statistically highly signicant i.e. Spearman r= 0.8450, P value (two-tailed) was < 0.0001*** . survival rate for the Score 0, 2 was almost 100% and as the score increases i.e. 3,4,5,6 there survival percentage also decrease approximately to 25 %, 5% and 0%,0% respectively. Conclusion :It can be concluded from our study that there was signicantly higher coreltaion between the Prognostic score and mortality of the patients hence this score could be reliable tool for the assessment of the severe patients and prompt and aggressive treatment for the better outcome

scholarly journals Serum albumin as predictor of post-operative morbidity and mortality

2017 ◽  
Vol 4 (3) ◽  
pp. 1078
Author(s):  
Latika Sharma ◽  
Poojan M. Purohit ◽  
Dharmendra Pipal ◽  
Saurabh Kothari ◽  
Harshit Srivastava ◽  
...  
Keyword(s):  
Serum Albumin ◽  
Protein Energy Malnutrition ◽  
Organ System ◽  
Morbidity And Mortality ◽  
Surgical Patients ◽  
P Value ◽  
Age Group ◽  
Operative Morbidity ◽  
Medical College ◽  
Protein Energy

Background: Protein energy malnutrition affects every organ system. So correct assessment of nutritional status is important as malnourishment is a risk factor for morbidity and morality in surgical patients. In our study, serum albumin has been taken as parameter for nutritional assessment.Methods: Study is conducted on 50 patients admitted in Department of General Surgery, Dr. Sampurnanand Medical College and associated Hospital, Jodhpur, Rajasthan, India for surgeries during January 2014-December 2015. Data was analyzed using Z-test and Fischer exact t-test and p value was calculated. P value <0.05 is considered statistically significant.Results: Patients with serum albumin <3gm/dl had more complications with maximum number of complications in age group of 41-60 year group. This finding was statistically significant.Conclusions: Low serum albumin patients has more post-operative complication than those with normal level and so is a good indicator of post-operative morbidity and mortality.

scholarly journals Role of adenosine deaminase and lymphocyte/neutrophil ratio in the diagnosis of tuberculous pleural effusion in patients with exudative pleural effusion

2017 ◽  
Vol 6 (1) ◽  
pp. 144
Author(s):  
Bijaya K. Behera ◽  
Sathish K. TN
Keyword(s):  
Pleural Effusion ◽  
P Value ◽  
Age Group ◽  
College Hospital ◽  
Tuberculous Pleural Effusion ◽  
Medical College ◽  
Combined Use ◽  
Medical Wards ◽  
Exudative Pleural Effusion

Background: Present study was conducted with an objective to evaluate the role of ADA and lymphocyte/neutrophil ratio in the diagnosis of tuberculous pleural effusion in patients with exudative pleural effusion and to analyze the cause of non-tuberculous exudative pleural effusion.Methods: This hospital based observational study was conducted from August 2011 to September 2013 with a total number of 120 patients of exudative pleural effusion who were admitted in medical wards of MKCG Medical College Hospital, Berhampur, Odisha, India. Patients with transudative pleural effusion, age less than 12years and those who were haemodynamically unstable were excluded from the study. Statistical analysis was done using standard statistical techniques.Results: A total number of 120 patients with exudative pleural effusion were analyzed. 83 patients were males and 37 patients were females. Maximum no of patients were seen in the age group of 21-40 years. Total ADA was found to be >40 U/L in all cases of TB effusion. All cases of TB effusion were lymphocyte predominant with L/N ratio > 0.75. In case of exudative pleural effusion due to non-tuberculous etiology L/N ratio was <0.75. P Value <0.0001 was considered extremely significant for L/N ratio for TB effusion.Conclusions: ADA value more than 100 U/L was observed only in patients of tuberculous effusion. L/N ratio was >0.75 in 97 patients of tuberculous effusion and none of the non-tuberculous effusion. Combined use of ADA and L/N ratio is more efficient means for diagnosing tuberculous pleural effusion than the use of ADA alone.

scholarly journals Comparison of a Combination of Caudal Levobupivacaine with Fentanyl and Levobupivacaine Alone for Alleviating Postoperative Pain During Infraumbilical Procedures in Children Under 3 Years

2019 ◽  
Vol 12 (1) ◽  
pp. 19-25
Author(s):  
Muralidar Vakkapatti ◽  
Thrivikram Shenoy ◽  
Sonal Bhat
Keyword(s):  
Analgesic Efficacy ◽  
P Value ◽  
Age Group ◽  
Parental Consent ◽  
Caudal Block ◽  
Physical Status ◽  
Medical College ◽  
Block Randomisation ◽  
To Receive ◽  
Caudal Blockade

Background: To compare the post-operative analgesic efficacy of caudal blockade using levobupivacaine alone and a combination of fentanyl with levobupivacaine in children under 3 years undergoing infraumbilical surgeries. Combination of levobupivacaine with fentanyl and levobupivacaine alone in children for caudal block was never studied before. Hence there was a need for the study. Methods: After approval from Institutional Ethical Committee, Kasturba Medical College, Mangaluru, 60 patients of age group 0-3 years, either sex of ASA physical status 1 and 2 undergoing infraumbilical surgeries were chosen after written parental consent and were randomised into 2 groups of 30 each L and LF using computer generated block randomisation to receive caudal blocks. Post operatively assessed for pain using CHIPPS scale at 2, 4, 6, 12 and 24 hours and compared in both groups. Results: Out of 60 patients, 30 in each group [L and LF], CHIPPS scores at 2, 4, 6, 12 and 24 hours post-operatively exhibited a p-value of 0.545, 0.492, 0.626, 0.166, and 0.329 respectively [not significant]. Mean duration of analgesia was 14.60 in Group L & 17.67 in Group LF with a t test p value of 0.119 [not significant]. Conclusion: Combination of fentanyl with levobupivacaine when compared to levobupivacaine alone for caudal block was equianalgesic in children less than 3 years undergoing infra umbilical procedures.

scholarly journals Prevalence of subclinical hypothyroidism in cases of cholelithiasis

2017 ◽  
Vol 5 (1) ◽  
pp. 34
Author(s):  
Brijendra Singh Raghuwanshi ◽  
Sandeep Jain ◽  
Mahendra Damor ◽  
Naveen Kumar Patbamniya
Keyword(s):  
Prospective Study ◽  
Subclinical Hypothyroidism ◽  
P Value ◽  
Age Group ◽  
Provisional Diagnosis ◽  
Abdominal Ultrasonography ◽  
Medical College ◽  
Gandhi Medical College ◽  
A Prospective Study ◽  
Multiple Stone

Background: This prospective study was carried out to analyse the prevalence of subclinical hypothyroidism in patients of gall stones.Methods: A prospective study was carried out in the Gandhi Medical College and associated Hamidia Hospital Bhopal from 2015 to 2016. Data was collected from patients who were admitted in surgical wards, with a provisional diagnosis of cholelithiasis. Patient was diagnosed cholelithiasis on abdominal ultrasonography and was tested for having subclinical hypothyroidism by testing fasting blood samples for serum TSH.Results: A total of 50 patients of cholelithiasis were included in present study. Females were 42 out of 50 (84%) and males were 8 out of 50 (16%). Most common age group was 41-50 (36%) correct (insignificant at p<0.05). 12 (24%) out 50 patients were hypothyroid. Out of total 42 females 11(26.19 %) were hypothyroid (insignificant at p<0.05). All stones in hypothyroidism patients were >1cm and overall 58% stones were >1cm (statically significant P<0.05). 03 out of 12 hypothyroidisms (25%) patient had single stones while 9 (75%) patient have multiple stone (statically significant P value <0.05). In hypothyroid cases most stones were of cholesterol type (58%) (Statically significant at P value≤0.05).Conclusions: Early diagnosis of hypothyroid state at subclinical level by monitoring TSH level so that they can be treated at early stages and burden of Cholelithiasis thus can be prevented.

scholarly journals Prevalence of hypothyroidism in reproductive age group in rural population of Haryana and its effects on menstrual disturbances

2021 ◽  
Vol 10 (2) ◽  
pp. 567
Author(s):  
Priyanka Yadav ◽  
Geetika Arora
Keyword(s):  
Thyroid Dysfunction ◽  
Management Plan ◽  
Reproductive Age ◽  
P Value ◽  
Age Group ◽  
College Hospital ◽  
Medical College ◽  
Menstrual Irregularities ◽  
Reproductive Age Group ◽  
Menstrual Disturbances

Background: Menstrual disorders are a common problem in reproductive age females. These disorders may cause significant anxiety for patients and their families. Thyroid dysfunction is one of the common cause of menstrual irregularities. Aim of the study was to determine the prevalence of hypothyroidism in reproductive age group women (15-45years), describe its various modes of clinical presentation and to assess the menstrual pattern in women with hypothyroidism.Methods: Prospective observational hospital based study during a period of 6 months (January 2020 to June 2020) on patients presenting in OPD in department of obstetrics and gynaecology, SGT medical college, hospital and research institute, Budhera, Gurgaon.Results: Prevalence of hypothyroidism was found to be 52.6% (190 out of total 338 patients) and it increased with increasing age group. 213 patients out of total came with complains of menstrual irregularities. 49.2% with normal menstrual cycle had hypothyroidism while 60.4% presenting with irregular heavy menstrual bleeding had hypothyroidism, p value being 0.019 which was statistically significant.Conclusions: Menstrual irregularities increase with severity of hypothyroidism. So screening for thyroid dysfunction should be included in management plan of menstrual disturbances.

scholarly journals Development of a Novel Prognostic Score Combining Clinicopathologic Variables, Gene Expression and Mutationprofiles for Lung Adenocarcinoma

2020 ◽  
Author(s):  
Guofeng Li ◽  
Guangsuo Wang ◽  
Yanhua Guo ◽  
Shixuan Li ◽  
Youlong Zhang ◽  
...  
Keyword(s):  
Gene Expression ◽  
Lung Adenocarcinoma ◽  
Competing Risks ◽  
Risk Score ◽  
Prognostic Score ◽  
The Cancer Genome Atlas ◽  
Time Dependent ◽  
P Value ◽  
Modeling Framework ◽  
Free Survival

Abstract Background: Integrating phenotypic and genotypicinformation to improve prognostic prediction is under active investigation for lung adenocarcinoma (LUAD). In this study, we developed a new prognostic model for event-free survival (EFS)and recurrence-free survival (RFS) based on the combination of clinicopathologic variables, gene expression and mutation data. Methods: We enrolled a total of 408 patients from the Cancer Genome Atlas Lung Adenocarcinoma (TCGA-LUAD) project for the study. We pre-selected gene expression or mutation features, and constructed 14 different input feature sets for predictivemodel development.We assessed model performance with multiple evaluation metrics including the distribution of C-index on testing dataset, risk score significance and time-dependent AUC under competing risks scenario.We stratified patients into higher and lower-risk subgroups by the final risk score, and further investigated underlying immune phenotyping variations associated with the differential risk.Results: The model integrating all three types of data achieved the bestprediction performance. The resultant risk score provided a higher-resolution risk stratification than other models within pathologically-definedsubgroups. The score could account for extra EFS-related variationsthat were not captured by clinicopathologic scores. Being validated forRFS prediction under a competing risks modeling framework, the score achieved a significantly higher time-dependent AUC as compared to that of the conventional clinicopathologic variables-based model (0.772 vs. 0.646, p-value< 0.001). The higher-risk patients were characterized with transcriptionalaberrations of multiple immune-related genes, and a significant depletion of mast cells and natural killer cells. Conclusions: We developed a novel prognostic risk score with improved prediction accuracy,using clinicopathologic variables, gene expression and mutation profiles as input, for LUAD. Such score was an significant predictor of both EFS and RFS.Trail registration: This study was based on public open data from TCGA and hence the study objects were retrospectively registered.

scholarly journals Comparison of Efficacy of Nebulisation with Salbutamol versus Adrenaline in Acute Bronchiolitis in Children aged Two Months to Two Years

2019 ◽  
Vol 8 (1) ◽  
pp. 27-32
Author(s):  
Vijay Kumar Sah ◽  
Arun Giri ◽  
Sanjay Sah ◽  
Niraj Niraula
Keyword(s):  
Age Groups ◽  
College Teaching ◽  
Assessment Instrument ◽  
P Value ◽  
Age Group ◽  
Acute Bronchiolitis ◽  
Medical College ◽  
Group A ◽  
One Year ◽  
Group B

Background: Bronchiolitis is an acute, highly communicable lower respiratory tract infection. A variety of agents ranging from nebulised racemic epinephrine, salbutamol and routinely available levoepinephrine have been tried. The Present study was aimed at comparing the effectiveness of adrenaline and salbutamol in acute bronchiolitis in children aged 2 months to 2 years. Materials and Methods: The Present study was conducted at Nobel medical College Teaching Hospital over the period of one year from Feb 2018 to Jan 2019. Two different cohorts were identified in which clinically diagnosed cases and were grouped into Group A and Group B to receive the different drugs as per the study protocol. Respiratory Distress Assessment Instrument (RDAI) Scores was used for clinical assessment. Results: The age of the patients ranged from 2 months to 24 months with a median of 8 months. The males constituting about 57.42% of the study population of 155 patients. On comparing the prenebulisation variables with 10 and 30 minutes post nebulisation values, it was found that Both adrenaline and salbutamol caused overall significant improvement in RR (p-value <0.00001 in both groups) except in the age group of 19-24 months. Adrenaline was seen to be superior to salbutamol in decreasing the RR (p<0.0001) except for children in the age group of 19-24months. Adrenaline also caused greater rise in heart rate in comparison to salbutamol in all age groups. Conclusion: This study concludes that Adrenaline was seen to be superior to salbutamol in decreasing the RR and RDAI, although it showed variance with age.

SARS-COV-2: RT-PCR CYCLE THRESHOLD (CT) VALUE AT DIAGNOSIS AND ITS RELATION TO AGE AND SEX IN ASSAM, INDIA

2021 ◽  
pp. 28-30
Author(s):  
Runumi Chowdhury ◽  
Malavika Barman ◽  
Devyashree Medhi ◽  
Sumi Deka ◽  
Bandeepa Duarah ◽  
...  
Keyword(s):  
Old Age ◽  
Virus Disease ◽  
Age Groups ◽  
P Value ◽  
Age Group ◽  
Global Public Health ◽  
Rt Pcr ◽  
Corona Virus ◽  
Gender And Age ◽  
The Difference

COVID-19 (corona virus disease 2019) is a global public health emergency caused by a new corona virus with severe acute respiratory syndromelike characteristics (SARS-CoV-2). We aimed to evaluate whether gender and age are major risk factors for SARS-CoV-2 infection. For the study, 300 positive cases diagnosed during the period of July 2020 to September 2020 were included. Results showed that 69% of study samples were male of which 84% were in the >51 years old age group. And 31% of study samples were female of which 63% were in the 4-19 years old age group. ANOVAresults indicated that the means of Ct values varied signicantly between age groups (F=2.703; p-value= 0.045). The lower Ct values were recorded in males (29.01±4.35) in comparison to females (29.84±3.98) while, the difference between the means of the two groups was not signicant. Our study concluded that males have higher viral load than females and for both sexes, age was found to be a signicant risk factor for severity of COVID-19.

EPIDEMIOLOGY AND OUTCOMES OF ELECTRIC BURN INJURY AT TERTIARY CARE CENTER IN JODHPUR, RAJASTHAN

2019 ◽  
Vol 3 (6) ◽  
Author(s):  
Bharti Saraswat ◽  
Ashok Yadav ◽  
Krishna Kumar Maheshwari
Keyword(s):  
Burn Injury ◽  
Low Voltage ◽  
Care Center ◽  
Tertiary Care ◽  
The Body ◽  
Electrical Injury ◽  
Age Group ◽  
Electric Circuits ◽  
Medical College ◽  
Social Burden

Background- Electric burns and injuries are the result of electric current passing through the body. Temporary or permanent damage can occur to the skin, tissues, and major organs. Methods- This prospective study was carried out on patients admitted in burn unit of department of surgery M.G. Hospital associated with Dr. S.N. Medical College Jodhpur. Records of the patients admitted from January 2018 to December 2018 were studied. Bed head tickets of the patients evaluated in detail. Results- In our study out of 113 patients maximum no. of patients were in age group of 21-30 years 44 (38.94%) followed by age group <11 years in 21 (18.58%) patients and age group of > 60 years in only 3 (2.65%).39 (34.51%) patients were farmer and 15 (13.27%) were electrician in out of 113 total patients, while 37 (32.74%) were without any occupation. 65 (57.52%) cases of high voltage (HV) electrical injury and 48 (42.48%) cases were of low voltage (LV) electrical injury. Conclusion- Morbidity leading to permanent disabilities make the person physically dependent on others. It can be prevented by educating the people about the proper handling to electric circuits & devices. Proper communication among the electricians may help in lowering such accidents. Proper rehabilitation of the handicapped person & employment to the member of the affected family may reduce the social burden caused by such electricity concerned accidents.

Rapid detection of Rotavirus antigen in stool sample of acute diarrheic children

2012 ◽  
Vol 6 (1) ◽  
pp. 11-13
Author(s):  
Sushmita Roy ◽  
S.M. Shamsuzzaman ◽  
K.Z. Mamun
Keyword(s):  
Stool Sample ◽  
Rapid Detection ◽  
Cross Sectional Study ◽  
Rapid Diagnosis ◽  
Age Group ◽  
College Hospital ◽  
Cross Sectional ◽  
Rotavirus Infection ◽  
Medical College ◽  
Stool Samples

Rotavirus is one of the leading causes of pediatric diarrhea globally. Accurate and rapid diagnosis of Rotavirus diarrhea should reduce unnecessary use of antibiotics and ultimately reduce drug resistance. Study was designed for rapid diagnosis of Rotavirus antigen in stool sample by ICT (Immunochromatographic test) as well as to observe the seasonal variation of rotavirus infection. This cross sectional study was carried out in the department of Microbiology, Dhaka Medical College from January 2011 to December 2011. Eighty stool samples were collected from Dhaka Shishu Hospital and Dhaka Medical College Hospital. All samples were tested for rotavirus antigen by ICT. Among 80 patients, 42 (52.5%) samples were positive for rotavirus antigen. Among these 42 positive samples, 30 (71.43%) were from 0-12 months of age group, 10 (23.81%) from 13 to 24 months of age group and rest 2 (4.76%) from 25 to 36 months of age group. Rotavirus Ag was detected in stool samples from January to April and another peak episode from October to December. Considering the importance of Rotavirus associated diarrhea, rapid detection of Rotavirus infection in human is substantially needed and should be routinely practiced.DOI: http://dx.doi.org/10.3329/bjmm.v6i1.19354 Bangladesh J Med Microbiol 2012; 06(01): 11-13

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