scholarly journals Role of Thyroid Stimulating Immunoglobulins (TSI) in Early Diagnosis of Patients with Euthyroid Grave’s Ophthalmopathy

2020 ◽  
Vol 36 (4) ◽  
Author(s):  
Mohammad Idris ◽  
Muhammad Zubair Umer ◽  
Eemaz Nathaniel ◽  
Muhammad Iqbal ◽  
Adnan Zar

OBJECTIVE: to determine the role of thyroid stimulating immunoglobulin (TSI) in early diagnosis of patients with euthyroid grave’s ophthalmopathy visiting Oculoplastic service of a tertiary care centre        Study design: cross sectional descriptive study  Place and Duration of Study: Oculoplastic service, out patient department of ophthalmology, -------from August 2015 to August 2016. Methodology: ninety patients of both the genders with euthyroid Greave`s Ophthalmopathy at any stage of severity of the disease by non-probability purposive sampling technique. One-way ANOVA test was also done for TSI with Age groups and Gender. RESULTS: Among 90 patients, Females were more than males, 68.9% and 31.1% respectively. 4 age groups were made in which age group of 41 – 55 years patients were more (37.8%) and after that was patients of more than 56 years of age (32.2%). 84% had their thyroid stimulating immunoglobulin (TSI) test positive. Cross tabulation was performed for TSI with Gender. 84.4% of the males and females had their TSI positive with females having more tests positive than males, 55.6% and 28.9% respectively with a p value of 0.139.  CONCLUSION: TSI is positive in majority of female Euthroid Graves ophthalmopathy patients visiting Oculoplastics clinics in age having 41 – 55 years. The association of TSI with gender showed higher significance than age. Early diagnosis with the help of TSI without any expensive investigations even when other thyroid function tests are normal can prevent complications especially ophthalmopathy by timely referral to endocrinologist.

2020 ◽  
Vol 58 (229) ◽  
Author(s):  
Bikram Kafle ◽  
Bikram Khadka ◽  
Mohan Lal Tiwari

Introduction: Patients with thyroid disorders are more prone to develop depressive symptoms and conversely depression may be accompanied by various subtle thyroid abnormalities. The aim of the study was to estimate the prevalence of thyroid dysfunction in depression. Methods: This is a descriptive cross-sectional study conducted at Devdaha Medical College and Research Institute employing a simple random sampling technique during the period of August 2019-January 2020. The research was approved by the Ethical Committee of the Institutional Review Board of Devdaha Medical College and Research Institute. The protocol approval number is 009/019. Data analysis was done in Statistical Package for the Social Sciences (Version 23). Results were presented as frequencies and percentages where required. Results: Among 263 patients with depression, 69 (26.2%) had abnormal thyroid status with most common being subclinical hypothyroidism 32 (12.2%), 13 (4.9%) overt hypothyroidism and 7 (2.7%) overt hyperthyroidism. Conclusions: The prevalence of thyroid dysfunction is high among patients with depression. We recommend to conduct routine thyroid function tests for all the patients with depression.


2021 ◽  
Vol 8 (8) ◽  
pp. 425-428
Author(s):  
Lipika Panda ◽  
Prafulla Chandra Mahapatra ◽  
Kamala Kanta Sahoo

BACKGROUND We wanted to estimate the incidence and prevalence of ocular injuries among occupational workers in welding and grinding industry treated in a tertiary care hospital, determine the major types of ocular morbidities in welding and grinding workers and identify the vulnerable age groups suffering from ocular injuries due to welding and grinding. METHODS This hospital based cross-sectional study was carried out among 712 patients having ocular injuries only for occupational workers doing welding, grinding or polishing work. The study period was from 01 / 01 / 2018 to 30 / 06 / 2018. The study was conducted in the Department of Ophthalmology, Hi-Tech Medical College and Hospital. All patients were assessed for demographic distribution, detailed ocular evaluation and a questionnaire related to awareness about the injuries and safety measures taken during the work. RESULTS During the period of study, 712 patients who had ocular injuries due to welding and grinding work were included in the study. The mean age was 33.87 years with a standard deviation (SD) of 9.86. There were no female workers who reported such injuries. Most injuries were corneal foreign body (63.90 %), conjunctival foreign body (2.81 %), conjunctivitis due to fumes (11.94 %), laceration (8.71 %) and keratoconjunctivitis (12.64 %). CONCLUSIONS To complement standard epidemiological research, the narrative accident text offers useful evidence. Staff conducting a welding job or working with local welders should be qualified to recognise possible dangers and appropriate protective equipment should be used to prevent eye injury. KEYWORDS Ocular Injuries, Welding & Grinding Work, Risk Factor for Eye Injuries


2021 ◽  
Vol 8 (11) ◽  
pp. 3375
Author(s):  
Jaganmoy Maji ◽  
Debjyoti Mandal

Background: Cholelithiasis is a common pathology of the gall bladder affecting about 10 to 15% of the adults in western countries and 2 to 29% in India. More than 80% of the patients with cholelithiasis are asymptomatic. Hypothyroidism may cause gall stone formation due to the hyperlipidemia, motility disorders affecting the bile duct and sphincter of Oddi.Methods: This was a descriptive cross-sectional study conducted at Department of Surgery, Bankura Sammilani Medical College and Hospital, Bankura from March 2019 to February 2020 for duration of one and half year. The sample size was 54 and consecutive non-probability sampling technique was used for the sampling. All the collected data were recorded in a pre-designed proforma and analyzed in MS excel.Results: Out of 54-patients with cholelithiasis, 28% patients were from the age group 45-54 years.40% patients were hypothyroid pre-dominantly females. Among 30-female patients 11 (26.82%) were hypothyroid and among 11-male patients 2 (15.38%) were hypothyroid. Hypothyroidism in male and female was statistically significant.Conclusions: This study was introduced to determine the relationship between hypothyroidism and cholelithiasis. It was concluded that hypothyroidism was more common in female, obese and elder patients. The gender distribution of the hypothyroidism in patients with cholelithiasis was statistically significant while all other variables were statistically not significant.  


JKEP ◽  
2019 ◽  
Vol 4 (2) ◽  
pp. 104-113
Author(s):  
Ririn Nur Indah sari ◽  
Sari Windyastuti ◽  
Tri Sakti Widyaningsih

Nurse workload is very influential on child play therapy assistance caused by workload excessive workload, lack of facilities and infrastructure, nothing schedule for play therapy and the number of nurses  only 18 nurses, According to theory Gilles with the number of beds 34 needed 29 nurses. The purpose of this research is to know the Relationship of Nurse Workload with The Role of Child’s Nurse in Mentoring Play Therapy in Room Dahlia RSUD Dr. H Sewondo Kendal. This type of research is descriptive correlation with cross sectional. The sampling technique with total sampling, a sample is 18 respondents. Retrieval data using questionnaires and then tested into Spearman Rank test statistic. Based on research found 10 respondents (55,6%) have hard workload and 8 respondents (44,4%) have a light workload. The role of nurses in good categories 5 respondents (27,8%) and categories less is 13 respondents (72,2%). From result of Spearman Rank test analysis, get result of coefficient correlation value -868 in category very strong and obtained p value = 0,000 < 0,05 it’s mean Ha accepted and H0 rejected. There is a relantionship between the nurses workload with the role of child nurses in mentoring play therapy.


Author(s):  
Angira Saha ◽  
Sakar Saxena ◽  
Romi Srivastava ◽  
Sanjeev Narang

Aim: To evaluate the role of biomarkers from blood samples of COVID-19 patients admitted in Index Medical College Hospital & R.C. Material & Methods: Hematological parameters such as Neutrophil lymphocyte ratio (NLR), Platelet lymphocyte ratio (PLR) & Systemic Inflammatory Index (SII) were studied in RT-PCR positive patients to evaluate the utility of these parameters for early diagnosis of COVID-19. Results: The study showed that there was statistically significant difference in test groups in reference to Neutrophil lymphocyte ratio (NLR) & SII values (p<0.05). But no statistically significant difference was observed between test groups in reference to Platelet lymphocyte ratio (PLR) values (p>0.05). Conclusion: Leukocyte, Neutrophil, NLR & SII values can be used in the early diagnosis of COVID-19. Keywords: NLR, SII, Leukocyte, Neutrophil


2019 ◽  
Vol 9 (2) ◽  
pp. 69-72
Author(s):  
Zulfiqar Ali Shaikh ◽  
Afifa Yaseen ◽  
Amna Yaseen ◽  
Subhana Akber

Background: Panoptic knowledge of dental professionals is required to provide care for patients with any dental problem which ranges from screening, emergency care or referral to alleviation of pain symptoms. Ideally to provide dental care, dental practice should be based on current clinical concepts originating from evidence-based dentistry which clearly demarcates a level between a tooth that is able to be restored so that intervention is done on it for esthetic and functional stability, or ready for extraction. Dental professionals' knowledge regarding tooth restorability is very crucial in restorative and preventive dentistry. The aim of this study was to assess the knowledge of dental professionals regarding tooth restorability. Methods: Knowledge regarding tooth restorability of dental professionals of Dow University of Health Sciences was assessed through a multi centered cross sectional study. A sample size of 140 participants was calculated using through open Epi version 3, and a convenient non-probability sampling technique was used. The study was conducted in May-June, 2018. An informed consent prior to the study was taken. The dental professionals were evaluated through a self- administered, structured questionnaire in English. The SPSS-23 was used to obtain results. The knowledge of the students was graded as adequate if >12 and inadequate if<12. Results: Out of 140 study participants, 113 (81%) dental professionals had significantly adequate knowledge (p-value <0.05); while 27 (19%) had inadequate knowledge. Among the respondents, 56% said that the traumatic dental injury must be treated by dentist whereas the others considered it to be treated by private doctor or by nearest hospital casualty. Conclusion: The knowledge of dental professionals working at teaching institutes is adequate; and as per their knowledge they might be taking right decisions regarding tooth restorability.


Author(s):  
Atul V. Rajkondawar ◽  
Amit Yele

Background: Chronic kidney disease (CKD) remains one of the major health problems in India. Renal function steadily deteriorates as age advances and advancing age has been indicted to have adverse implications in the disease progression to end stage renal disease (ESRD). With the present study, clinico-biochemical profiling of chronic kidney disease patients in geriatric age group as well as comparison with non-elderly patients was undertaken.Methods: In this cross-sectional observational study, 100 patients of CKD admitted in the tertiary care study centre were enrolled consecutively and assessed for symptoms, signs and biochemical parameters over two years. Study subjects were divided into two groups:- Group 1: Elderly patients- aged 60 years or more, and Group 2: Non-elderly patients- less than 60 years of age. Relevant comparisons were drawn statistically and tested for significance.Results: Pallor and pedal edema were observed to be the commonest clinical features across groups. Elderly group shows higher prevalence of severe anaemia (mean hemoglobin- 7.4 gm%). Higher prevalence of clinical and biochemical derangement was found in patients with relatively lower GFR. Elderly age group also had more prevalence of electrolyte abnormalities compared with non-elderly population, with statistically significant difference observed for hyponatremia (p value- 0.023), hypoproteinemia (p value- 0.0078) and blood urea level (p value- 0.0054).Conclusions: Understanding beforehand the biochemical abnormalities associated with old age in CKD patients helps in appropriate modifications in patient management.


2021 ◽  
Vol 1 (2) ◽  
pp. 31-37
Author(s):  
Dewi Puspa Cipta Utami

Introduction: The role of the family is the specific behavior expected by someone in the family member. Anxiety is a fear that is not clear and is not supported by the situation. Objective:  To Know the Relationship of Family Role to the Level of Anxiety in the Elderly in Hamlet 01 Kukusan Beji-Depok Method: The research method uses analytics with a cross-sectional approach. The study population was 288 people with a sample of 81 respondents using the Slovin formula. In the sampling technique using cluster sampling. Results: The results showed that the respondents with a bad family role as many as 41 (50.6%) anxiety levels of the middle aged were 59 (72.8%). The results of statistical tests using the chi-square test indicate that there is a significant or significant relationship between the role of the family and the level of anxiety of the elderly with a value of p-value 0.01. Conclusion: It was concluded that there was a relationship between the role of the family and the level of anxiety of the elderly in the Hamlet 01 Kukusan Beji District Depok City.


Author(s):  
Ambreen Ghouri ◽  
Bushra Mushtaq ◽  
Azra Ahmed ◽  
Najma Dalwani ◽  
Padma Bai ◽  
...  

Background: Obstetrical hemorrhage is leading cause of maternal mortality. UAE is termed safe and effective method for resolving hemorrhage. objective of this study was to determine efficacy of uterine artery ligation in management of obstetrical hemorrhage.Methods: This cross sectional observational using non-probability convenient sampling technique was carried out for six months. After ethical approval, females between 18 to 35 years diagnosed with obstetrical hemorrhage, uterine atony refractory to medical treatment, having active bleeding from placental side or having normal coagulation profile were while females with post-partum hemorrhage because of retained products of conception, due to genital tract trauma or with disseminated intravascular coagulation were excluded. Analysis of data was done using SPSS version 23.0. Quantitative variables were reported as mean and standard deviation and for qualitative variables, frequency and percentages. Chi-square test was applied keeping p-value of <0.05 as statistically significant.Results: From 109 females with mean age 47±5.25 years. In comparison of parity distribution, 62 (56.88%) were multiparous and 47 (43.12%) were primiparous. Type of bleeding observed was antepartum 36(33.03%), peripartum 39 (35.78%) and postpartum in 34 (31.19%). Efficacy of uterine artery ligation in management of obstetric hemorrhage was observed to be 35 (32.11%). The efficacy of uterine artery ligation in management of obstetric hemorrhage in three categories of age groups reported significant association (p=0.0005) and type of bleeding (p=0.025).Conclusions: Efficacy of UAE in different types of obstetrical hemorrhage reported in our study was lower than expected in about one-third of females.


2020 ◽  
pp. 14-15
Author(s):  
Gunjan Jain ◽  
Jigisha Patadia ◽  
Praful Bambhroliya

The burden of morbidity and mortality from Non-Communicable disease has risen worldwide and is accelerating in low-income and middle-income countries. Lifestyle-associated risk factors among adolescent are rampantly increasing throughout the world. They place a tremendous demand on health care systems and social welfare, cause decreased productivity in the workplace, prolong disability and diminish resources within families. A life course approach to preventive efforts addressing NCDs and their risk factors and behaviors will improve child and adolescent health but also decrease lifetime health care costs. Nevertheless, those risk behaviors are initiated usually in the adolescent’s age groups which are continued to adult. Therefore, this group is important target for primordial prevention. This study is a cross-sectional study which aims to determine the prevalence of risk factors among adolescents attending the tertiary care centre in Surat, district of Gujarat, conducted in March 2019 to June 2019. A total of 498 adolescents were screened using a structured questionnaire. The study documented that improper diet is the major risk factor while habits like smoking and alcohol consumption is fairly uncommon. Study recommends creating awareness among adolescents and promoting healthier lifestyle habits.


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