DEVELOPMENT OF PROGNOSTIC MODELS FOR CALCULATION OF ASYMMETRY COEFFICIENT OF CHEWING MUSCLE TONE AT VARIOUS STAGES OF ORTHODONTIC CORRECTION

2021 ◽  
pp. 74-79
Author(s):  
Ирина Владимировна Косолапова ◽  
Евгений Владимирович Дорохов ◽  
Михаил Эдуардович Коваленко
Keyword(s):  
Oral Fluid ◽  
Muscle Tone ◽  
Treatment Plan ◽  
Immunoglobulin A ◽  
Prognostic Models ◽  
Linear Regression Method ◽  
Asymmetry Coefficient ◽  
Functional Parameters ◽  
The Asymmetry ◽  
Resting Tone

Цель работы: Разработка прогностических моделей для оценки зависимости коэффициента асимметрии тонуса собственно жевательных мышц от функциональных параметров жевательных мышц и иммуноферментного состава ротовой жидкости на различных этапах ортодонтической коррекции. Материал и методы исследования: В исследовании приняли участие 82 пациента Детской клинической стоматологической поликлиники №2 г. Воронежа в возрасте от 6 до 12 лет с дистальной окклюзией зубных рядов, которым было рекомендовано лечение пластиночным аппаратом в модификации Шварца. Проводилась оценка функциональных параметров жевательных мышц: средней амплитуды биоэлектрической активности височных и подъязычных мышц, тонуса покоя и коэффициента асимметрии собственно жевательных мышц; количественное определение общих иммуноглобулинов G, А, M и секреторного иммуноглобулина A ротовой жидкости до начала лечения, через 3 и через 6 месяцев. Статистический анализ осуществлялся с использованием программ IBM SPSS Statistics 20, StatTech v. 1.2.0. Прогностическая модель, характеризующая зависимость количественной переменной от факторов, разрабатывалась с помощью метода множественной линейной регрессии. Результаты: Разработаны 2 прогностические модели. Полученные данные связаны с перестройкой функциональных параметров жевательной мускулатуры в результате ортодонтической коррекции. Вывод: Разработаны 2 прогностические модели для оценки зависимости коэффициента асимметрии тонуса собственно жевательных мышц от функциональных параметров жевательных мышц и иммуноферментного состава ротовой жидкости через 3 и 6 месяцев ортодонтической коррекции, которые позволят врачу грамотно выстроить план лечения, спрогнозировать его срок, повысить качество и эффективность диагностики The purpose of the work: Development of prognostic models for assessing the dependence of the asymmetry coefficient of the tone of the chewing muscles proper on the functional parameters of the chewing muscles and the immunoenzyme composition of the oral fluid at various stages of orthodontic correction. Material and methods of research: The study was attended by 82 patients of the Children's Clinical Dental Clinic No. 2 of Voronezh, aged 6 to 12 years, with distal occlusion of the dentition, who were recommended for treatment with a plate machine in the Schwartz modification. The functional parameters of chewing muscles were evaluated: the average amplitude of the bioelectric activity of temporal and sublingual muscles, the resting tone and the asymmetry coefficient of the chewing muscles themselves; quantification of total immunoglobulins G, A, M and oral fluid secretory immunoglobulin A before treatment, at 3 and 6 months. Statistical analysis was carried out using IBM SPSS Statistics 20, StatTech v. 1.2.0 (developer - Stattech LLC, Russia). A predictive model characterizing the dependence of a quantitative variable on factors was developed using the multiple linear regression method. Results: 2 prognostic models developed. The obtained data are related to reconfiguration of functional parameters of chewing muscles as a result of orthodontic correction. Conclusion: 2 prognostic models have been developed to assess the dependence of the asymmetry coefficient of the tone of the chewing muscles proper on the functional parameters of the chewing muscles and the immunoenzyme composition of the oral fluid after 3 and 6 months of orthodontic correction, which will allow the doctor to competently build a treatment plan, predict its duration, increase the quality and effectiveness of diagnosis

Atonic Seizures

1987 ◽  
Vol 9 (2) ◽  
pp. 43-49
Author(s):  
Michael S. Duchowny
Keyword(s):  
Clinical Presentation ◽  
Muscle Tone ◽  
Skull Fracture ◽  
Dental Trauma ◽  
Accurate Diagnosis ◽  
Correct Identification ◽  
Grand Mal ◽  
Important Challenge ◽  
Resting Tone ◽  
Atonic Seizures

Seizures consisting of rapidly arrested movement are relatively common and account for approximately 12% of all episodes. Atonic seizure is the preferred designation for this form of clinical presentation, although more descriptive terms such as "drop attack" and "epileptic fall" are also popular. Many clinicians still use the term "akinetic seizure," but this is inaccurate because attacks of behavioral immobility with preserved muscle tone and consciousness cannot be differentiated from absence seizures. Furthermore, it is unlikely that neurophysiologic mechanisms can arrest behavior without altering muscle tone or compromising consciousness. The accurate diagnosis and management of atonic seizures constitutes an important challenge for the practicing pediatrician. Whereas grand mal and petit mal seizures are well-known manifestations of epilepsy in childhood, seizures limited to the loss of muscle tone are more likely to go unrecognized. The large variety of nonepileptic conditions that mimic atonic seizures further adds to the difficulties of correct identification. DESCRIPTION Atonic seizures show considerable variation in presentation and severity. Typically, without warning, the voluntary muscles synchronously increase and then lose resting tone. No aura precedes these muscular changes. Both the myoclonic and atonic seizure components can cause the child to collapse limply to the ground. Massive myoclonus and loss of tone may even precipitate a violent fall from a sitting position (Fig 1), resulting in craniofacial injury, skull fracture, facial laceration, or dental trauma.

The asymmetry coefficient for interstellar scintillation of extragalactic radio sources

2005 ◽  
Vol 49 (3) ◽  
pp. 250-257 ◽  
Author(s):  
V. I. Shishov ◽  
T. V. Smirnova ◽  
S. A. Tyul’bashev
Keyword(s):  
Radio Sources ◽  
Asymmetry Coefficient ◽  
Extragalactic Radio Sources ◽  
Interstellar Scintillation ◽  
The Asymmetry

The cross-section and angular distribution of the D-D reactions below 50 keV

1953 ◽  
Vol 216 (1124) ◽  
pp. 57-65 ◽  
Keyword(s):  
Angular Distribution ◽  
Total Cross Section ◽  
Cross Section ◽  
Proportional Counter ◽  
Angular Distributions ◽  
Asymmetry Coefficient ◽  
Gas Target ◽  
The Asymmetry ◽  
The Cross ◽  
Bombarding Energy

A thin gas target was used and the particles from the reactions were detected by a proportional counter. The results show that the total cross-section for the two reactions is the same to within 1%, but that the angular distributions of the products are significantly different. The asymmetry coefficient for the reaction D( d , n ) 3 He is given by 0·31 + 0·0058 E , compared with 0·13 + 0·0047 E for reaction D( d , p ) 3 H, where E is the bombarding energy in kilovolts.

scholarly journals Fnk Model of Cracking Rate Calculus for a Variable Asymmetry Coefficient

2017 ◽  
Vol 69 (1) ◽  
pp. 72-81
Author(s):  
Vâlcu Roşca ◽  
Cosmin Mihai Miriţoiu
Keyword(s):  
Stainless Steel ◽  
Tensile Test ◽  
Mathematical Models ◽  
Asymmetry Factor ◽  
Polynomial Method ◽  
Asymmetry Coefficient ◽  
Type Specimens ◽  
The Asymmetry ◽  
Formula Method

Abstract In the process of materials fracture, a very important parameter to study is the cracking rate growth da/dN. This paper proposes an analysis of the cracking rate, in a comparative way, by using four mathematical models:1 - polynomial method, by using successive iterations according to the ASTM E647 standard; 2 - model that uses the Paris formula; 3 - Walker formula method; 4 - NASGRO model or Forman - Newman - Konig equation, abbreviated as FNK model. This model is used in the NASA programs studies. For the tests, CT type specimens were made from stainless steel, V2A class, 10TiNiCr175 mark, and loaded to a variable tensile test axial - eccentrically, with the asymmetry coefficients: R= 0.1, 0.3 and 0.5; at the 213K (-60°C) temperature. There are analyzed the cracking rates variations according to the above models, especially through FNK method, highlighting the asymmetry factor variation.

EVALUATE THE EFFECTIVENESS OF ONDANSETRON IN TREATING THE VOMMITING FOR CHILDREN < 5 YEARS OLD WITH ACUTE GASTROENTERITIS AT PEDIATRICS DEPARTMENT, HUE CENTRAL HOSPITAL

2011 ◽  
pp. 88-95
Author(s):  
Thi Cu Nguyen ◽  
Dinh Thai Uong
Keyword(s):  
Sample Size ◽  
Acute Gastroenteritis ◽  
Oral Fluid ◽  
Small Sample Size ◽  
Treatment Plan ◽  
Small Sample ◽  
Primary Study ◽  
Control Group ◽  
Study Group ◽  
Central Hospital

Background: To control the vommit symptom give more successful and easier to oral fluid infusion, reduce the cost and work if using IV infusion. All over the world there are many studies on using Ondansetron for vommint preventing in gastroenteritis in children and show the effectiveness and safety. At Hue, Ondansetron mainly use for vommit preventing for children patients treated by chemotherapy and radiotherapy. There was no study about using Ondansetron to vommit preventing and treating for children patients with acute gastroenteritis. The aim of this study is to evaluate the effectiveness of Ondansetron in vommit treating for children with acute gastroenteritis. Population and study methods: children from 6 mths to 5yrs with acute gastroenteritis at Pediatric department of Hue Central Hospital. Using the method of clinical intervention with control group. 2 groups had the similarity of age, gender, onset duration of vommit, dehydration situation. Sample size: 86 children in control group and 41 children for study group. Study group with intervention) : only one shoot Ondansetron 0,2mg/kg + treatment plan fordedration + Zinc suppement as IMCI guidelines. Control group: treating by treatment plan for dehydration + Zinc suppement as IMCI guidelines. Both two groups will follow up about the situation of vommit, watery stools and the amount of ORS, the amount of IV fluid. Result: The rate of patient without vommit in the time from intervention to hospital discharge: Group having Ondansetron was 56,1% in comparision with 5,8% in control group (p<0,01). The study group had the rate of patient with vommit ≥ 3 times was 7,3% lower than the rate of 54,7% in control group (p < 0,05). The avarage time of vommit in control group was higher than study group (0,71 ± 0,96 vs 2,45 ± 1,12, p<0,05). The rate of patiend need IV infusion in study group was 9,8%, control group was 37,2% (p < 0,05; RR = 0,33). Conclusion: In our study, Ondansetron had good result in vommit treating for children with acute gastroenteritis. It help to reduce vommit symptom, made patients easier in oral fluid and electrolyte providing, limited the IV fluid. We followed up carefully but it’s still no see the the side effects in patients having Ondansetron injection. However, it was just the primary study with small sample size and need more studies to evaluate accurately the effectiveness of Ondansetron in patients with acute gastroenteritis.

scholarly journals THE PROGRAM FOR CALCULATING THE ASYMMETRY COEFFICIENTS OF AEROSOL SCATTERING IN THE RED AND NEAR IR REGIONS OF THE SPECTRUM

2021 ◽  
pp. 163-167
Author(s):  
В.В. Пашнев ◽  
Ю.Я. Матющенко ◽  
В.В. Белозерских ◽  
А.В. Калачев
Keyword(s):  
Block Diagram ◽  
Scattered Light ◽  
Atmospheric Parameters ◽  
Asymmetry Coefficient ◽  
Angular Variation ◽  
Acceptable Error ◽  
Near Ir ◽  
Aerosol Scattering ◽  
Calculation Results ◽  
The Asymmetry

В настоящей работе представлено программное обеспечение, реализующее методику определения аэрозольного коэффициента асимметрии из результатов наблюдений интегрального коэффициента рассеянных световых потоков, оптической толщи и альбедо местности интерполяционным путем без применения аппарата решения обратных задач. В качестве исходных используются данные измерений углового хода яркости дневного безоблачного неба в солнечном альмукантарате при разной спектральной прозрачности атмосферы и альбедо подстилающей поверхности. Наблюдения выполняются в длинах волн 675, 870 и 1020 нм при зенитных углах Солнца 65÷750, при этом яркость может измеряться в любых единицах, включая непосредственно отсчеты фотометра. При обработке результатов мониторинговых наблюдений даже на одной длине волны требуется производить значительное количество однотипных вычислений, что делает задачу автоматизации расчетов атмосферных параметров, в частности, коэффициентов асимметрии, безусловно актуальной. Изложены требования к входным данным, представлена блок-схема алгоритма и описание интерфейса пользователя программы. Результаты расчетов выводятся в табличной форме. Программаобеспечивает приемлемую погрешность определения коэффициентов асимметрии и может быть использована в геофизике и климатологии при проведении расчетов поступления рассеянной солнечной радиации на земную поверхность с целью последующей оценки размеров частиц. In this paper, software is presented that implements the method for determining the aerosol asymmetry coefficient from the results of observations of the integral coefficient of scattered light fluxes, optical depth and albedo of the terrain by interpolation without using an apparatus for solving inverse problems. The data of measurements of the angular variation of the brightness of the daytime cloudless sky in the solar almucantar with different spectral transparency of the atmosphere and the albedo of the underlying surface are used as the initial data. Observations are carried out at wavelengths of 675, 870 and 1020 nm at zenith angles of the Sun 65 ÷ 750, while the brightness can be measured in any unit, including directly the readings of the photometer. When processing the results of monitoring observations, even at one wavelength, it is required to perform a significant number of calculations of the same type, which makes the task of automating the calculations of atmospheric parameters, in particular, the asymmetry coefficients, undoubtedly relevant. Requirements for the input data are stated, a block diagram of the algorithm and a description of the user interface of the program are presented. The calculation results are displayed in tabular form. The program provides an acceptable error in determining the asymmetry coefficients and can be used in geophysics and climatology when calculating the arrival of scattered solar radiation on the earth's surface in order to further estimate the particle size.

scholarly journals The structural-spatial reorganization of the arterial bed of the femur, knee and shin areas of the hind limbs of the rats

2020 ◽  
Vol 24 (2) ◽  
pp. 215-222
Author(s):  
T. O. Veresiuk ◽  
P. R. Selskyy ◽  
A. T. Televiak
Keyword(s):  
Femoral Artery ◽  
Ischemia Reperfusion ◽  
Morphometric Parameters ◽  
Control Group ◽  
Asymmetry Coefficient ◽  
X Ray ◽  
Hind Limbs ◽  
Spatial Reorganization ◽  
Vascular Dilatation ◽  
The Asymmetry

Annotation. The ischemic-reperfusion lesion, which occurs during the restoration of the arterial circulation, causes structural and spatial reorganization of the arterial bed of the hind limbs of the rats. Recently, more and more attention has been paid to the treatment and prevention of the ischemic changes are given to the nootopic medicines, among which carbacetam stands out. The aim of the study – to establish the manifestations of the structural-spatial remodeling of the arterial bed of the hind limbs of the rats in the femoral, popliteal and tibial anatomical areas during ischemia-reperfusion and under conditions of the correction with carbacetam. An X-ray examination was performed of the arterial bed of the hind limbs of 30 rats under conditions of the ischemia-reperfusion (group I) and 30 rats in the simulation of the ischemia-reperfusion, which were injected carbacetam once a day (5 mg/kg) during 14 days in postischemic period. There were 6 intact animals in the control group. Simulation of the ischemia was performed by applying SWAT rubber tourniquets on the hind limbs for 2 hours, and reperfusion by removal of the arterial tourniquet. The animals of the experimental groups were divided into 5 subgroups with reperfusion terms after 1, 2 hours and 1 day, as well as after 7 and 14 days. The filling of the arterial bed with a suspension of lead sulfide and the radiography were performed. Research morphometric parameters were calculated using the SEO Image Lab software of Sumy Electron Optics. The diameters of the main column (D0,), thicker (D1,) and thinner (D2,) subsidiary branches were determined, and the asymmetry coefficient (H2) was calculated. Statistical processing of the material was carried out using a program package “Microsoft Exсel”. Research results and their discussion. Visual analysis revealed dilatation of the main vascular columns and reduction of angioarchitectonics of the limb, most likely after 1 day, which was confirmed morphometrically. In particular, in the femoral region by 15.77 % (p<0.005) increased (D0) by 12.77 % (p<0.05) – (D1) and by 20.93 % (p<0.005) – (D2). and the asymmetry coefficient (H2) increased by 9.36 % (p<0.05). In the popliteal area at the end of 1 day there was an increase in the lumen of D0 by 18.49 % (p<0.005) and its subsidiary branches D1 and D2 by 15.8 % (p<0.05) and 25.12 % (p<0.05), respectively. The value of H2 increased in this group by 10.56 % (p<0.005). In the area of the tibia during this period there was an increase in the indicator (D0) by 19.54 % (p<0.05), and indicators D1 and D2 – by 12.58 % (p>0.05) and 23.51 % (p<0.05), respectively, and the asymmetry coefficient (H2) – increased by 11.78 % (p<0.05). After 14 days after the resumption of blood supply, the morphometric parameters of the arterial tees decreased and approached the level of the values of the control group. On the X-ray angiograms of the animals with using a correction, an also have signs of the vascular dilatation, but their intensity was less relative to the group, in which correcting was not performed. Thus, in the area of the femoral artery through 1 day of reperfusion marked on decreasing in D0 by 4.0 % (p<0.005), D1 by 2.0 % (p<0.005), D2 by 3.96 % (p<0.005), and H2 by 2.51 % (p<0.005) in the group with correction compared to similar indicators without correction. On the X-ray angiograms of the animals with using a correction, an also have signs of the vascular dilatation, but their intensity was less relative to the group, in which correcting was not performed. Thus, in the area of the femoral artery through 1 day of reperfusion marked on decreasing in D0 by 4.0 % (p<0.005), D1 by 2.0 % (p<0.005), D2 by 3,96 % (p<0.005), and H2 by 2.51 % (p<0.005) in the group with correction compared to similar indicators of the group without correction. At the levels of the popliteal artery, after the application of the correction, the index D0 was lower by 3.0 % (p<0.005), D1 by 2.02 % (p<0.005), D2 by 4.0 % (p<0.005), and H2 by 2.58 % (p<0.005) compared with a group of the animals without correction. In the tibia using of carbacetam caused a decrease in the values of D0 by 3.0 %, D1 by 3.0 % (p<0.005), D2 and H2 by 4.36 % (p<0.005) and 3.83 % (p<0.005) in accordance. Thus, simulated ischemia-reperfusion supplementation with morfo-functional reorganization of the arteries of the hind limbs of the rats at all studied levels after 1 hour of the reperfusion and reaching the highest values after 1 day. Gradually, returning of the studied indicators to the control group occurs after 14 days of the experiment, and the application of correction helps to return the basic parameters of vascular tees at all levels to the control group after 7 days of the experiment.

Complex Treatment and Prosthetic Rehabilitation of an Acquired Maxillofacial Defect with Tumor Invasion: Case Report

2021 ◽  
Vol 27 ◽  
Author(s):  
Li Jiajing ◽  
Ekaterina V. Kochurova ◽  
Narasimha M Beeraka ◽  
Natalya V. Lapina ◽  
Chang Weilong ◽  
...  
Keyword(s):  
Oral Fluid ◽  
Treatment Plan ◽  
Maxillofacial Surgery ◽  
Complex Treatment ◽  
Tumor Patient ◽  
Non Invasive ◽  
Post Surgery ◽  
Immunological Tests ◽  
Dental Rehabilitation

Background: A patient was evaluated with respect to the effects and results of a complex treatment plan for a complete dental rehabilitation. Several steps were required. Each step included immunological tests of salivary biomarkers. Clinical and immunological assessments were evaluated on Day 3, Week 2, Month 3, and Month 6 post-surgery. These evaluations guided the decision-making process with regard to preparation of a permanent prosthesis. Objective: The aim of the study is to evaluate the response of tissues and organs of the maxillofacial region in patients during dental rehabilitation after maxillofacial surgery. Method: Complex treatment and rehabilitation involving cooperation between the specialists in maxillofacial surgery, prosthetic dentistry, and cancer immunology. Results: Long-term monitoring and clinical examination showed a direct relationship between the patient’s clinical and dental status and the changes in oral fluid biomarkers. Conclusion: The data revealed that the oral fluid biomarkers reflected the patient’s adaptation to prosthodontic rehabilitation. Treatment and monitoring of a maxillofacial tumor patient could use biomarkers as a non-invasive indicator.

scholarly journals Use of oral fluids to detect anti Lawsonia intracellularis antibodies in experimentally infected pigs

2020 ◽  
Vol 40 (12) ◽  
pp. 970-976
Author(s):  
Michelle P. Gabardo ◽  
José Paulo H. Sato ◽  
Talita P. Resende ◽  
Luisa V.A. Otoni ◽  
Lucas A. Rezende ◽  
...  
Keyword(s):  
Oral Fluid ◽  
Immunoglobulin A ◽  
Standard Technique ◽  
High Specificity ◽  
Post Inoculation ◽  
Lawsonia Intracellularis ◽  
Serum Samples ◽  
Diagnostic Assays ◽  
Specificity And Sensitivity ◽  
Moderate Sensitivity

ABSTRACT: Several pathogens and antibodies derived from serum or produced in tissues associated with the oral cavity are present in the oral fluid (OF). Considering the applicability of this alternative sample, recent studies in veterinary medicine have tested OF as a replacement for serum in diagnostic assays. The aim of this study was to standardize the immunoperoxidase monolayer assay (IPMA) to detect anti-Lawsonia intracellularis immunoglobulin A (IgA) and immunoglobulin G (IgG) in OF samples from experimentally infected pigs. Sixty-two pigs were divided into two groups: control (T1, n=30) and inoculated with L. intracellularis (T2, n=32). Blood, OF and fecal samples were collected at 0, 7, 14, 21, 28 and 42 days post-inoculation (dpi). Some adaptations of the standard technique for serum were made to IPMA for the detection of IgA and IgG in OF. The IPMA showed high specificity and sensitivity for serum samples and high specificity and moderate sensitivity for the detection of IgA and IgG in OF. There was high agreement between the results of serum IgG and OF IgA and IgG. Based on our results, oral fluid samples may be used for the evaluation and determination of anti-L. intracellularis antibodies in pigs, but not for individual diagnosis of swine proliferative enteropathy.

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