scholarly journals Lysis Test of Ascaris lumbricoides Eggs After Giving Ethanol Extract of Chinese Ketepeng Leaves (Cassia alata L.)

2021 ◽  
Vol 9 (2) ◽  
pp. 9-15
Author(s):  
Sri Kartini ◽  
Ira Oktaviani Rz
Keyword(s):  
Herbal Medicine ◽  
Morphological Change ◽  
Ascaris Lumbricoides ◽  
Laboratory Experiments ◽  
Morphological Changes ◽  
Herbal Medicines ◽  
Ethanol Extract ◽  
Cassia Alata ◽  
Synthetic Drugs ◽  
Intestinal Worms

soil or known as soil transmitted helminth (STH). Infection caused by these parasites can be eradicated by giving synthetic drugs and herbal medicines. One of the plants that can be used as herbal medicine is ketepeng cina (Cassia alata L.). chinese ketepeng leaves (Cassia alata L.) have one benefit, namely to treat intestinal worms. This study aims to determine the morphological changes of eggs Ascaris lumbricoides after the administration of ethanol extract of chinese ketepeng leaves (Cassia alata L.) with concentration 1%, 2%, 3%, 4%, 5%. The method used in this study is laboratory experiments. The results of this study indicate that the ethanol extract of chinese ketepeng leaves (Cassia alata L.) in concentrated 4% and 5% changes color in the eggs but there is no morphological change in eggs. From this study it can be concluded that the ethanol extract of chinese ketepeng leaves (Cassia alata L.) is not able to damage the morphologi of Ascaris lumbricoides worm eggs.

scholarly journals Herbal Medicines: Can We Do without Pharmacologist?

2007 ◽  
Vol 4 (s1) ◽  
pp. 41-43 ◽  
Author(s):  
Gioacchino Calapai ◽  
Achille P. Caputi
Keyword(s):  
Herbal Medicine ◽  
Initial Phase ◽  
Herbal Medicines ◽  
Herbal Extracts ◽  
Efficacy And Safety ◽  
Medicine Use ◽  
Medicinal Products ◽  
Synthetic Drugs ◽  
Scientific Value ◽  
Poor Efficacy

The increase of herbal medicine use led many scientists to contribute to the research in this field. Also a few pharmacologists, after an initial phase of correct criticisms, today recognize the possibility of investigating the scientific value of medicinal products composed essentially of vegetable extracts. However, it is logical to pose the questions: (i) is there a role for the pharmacologist in herbal medicine (or phytotherapy)? (ii) can we do without pharmacologists’? First, two worlds—drug researchers (pharmacologists) and herbal medicines—yesterday appearing in opposition, are today closer and it is not unusual to read scientific works describing herbal extracts in journals traditionally dedicated to the study of synthetic drugs. Second, clinical application of herbal medicines is evaluable through the methods of modern clinical pharmacology. Efficacy and safety of medicinal plants represent naturally the object of interest for the pharmacologist and it is surely this aspect which gives the most important information on herbal medicine use. Many plants have been studied and results published showing, one time good or another poor, efficacy. Safety aspects of some of the most frequently used plants are now well known. For example, today we learn to usehypericumand we do not give it to patients taking other drugs because the interactions ofhypericumwith them. Contraindications of other plants, often represented by interactions with drugs, are finally known (Ginkgo bilobaand drugs acting on blood coagulation). In conclusion, antagonistic behavior of pharmacologists versus herbal medicines is not useful. On the contrary, modern phytotherapy needs the contribution of researchers usually trained to evaluate efficacy and safety of medicinals.

scholarly journals Antidermatophytic, the anticancer and antioxidant activity of Cassia alata ethanolic extract and its phytochemical analysis

2019 ◽  
Vol 10 (2) ◽  
pp. 838-845
Author(s):  
Sujatha J ◽  
Rajeshkumar S ◽  
Lakshmi T
Keyword(s):  
Cytotoxic Activity ◽  
Cancer Cells ◽  
Morphological Changes ◽  
Radical Scavenging ◽  
Ethanol Extract ◽  
New Drugs ◽  
Phytochemical Analysis ◽  
Standard Drug ◽  
Cassia Alata ◽  
Stomach Pain

Cassia alata is used traditionally to cure various diseases like ulcers, stomach pain and fever. The potential of antidermatophytic, free radical scavenging and cytotoxic activity of ethanol leaves extracts of C. alata was studied. The preliminary phytochemical screening assay elucidates that presence of carbohydrates, tannin, phenol, saponin, flavonoid, steroid, terpenoids, glycosides, and alkaloids. Further phytochemical extraction was done by GC-MS, HPLC and FTIR. GC-MS analysis confirms that the presence of two major compounds namely Hexadecanoic acid and Oleic acid with four minor compounds. HPLC techniques revealed that the presence of two major compounds observed in two different retention time. FTIR spectrum revealed that the presence of carboxylic groups, alkanes, aldehydes and aliphatic amines in the ethanol extract of C. alata leaves. Cytotoxic effect of ethanol extract was assayed at different concentrations like 10, 25, 50 and 100 μg/ml against human epithelial carcinoma (A431). At100 μg/ml of ethanol concentration, 93.26±5.44 (%) and 82.45±2.44 (%) percentage of cancer cells were inhibited by ethanol extract and standard drug, respectively. Microscopic images of cancer cells treated with ethanol extract confirm the morphological changes and shrinkages of cells leads to cell death. These results were suggesting that Cassia alata exhibit high potential antioxidant, antidermatophytic and cytotoxic activity and also it could serve as alternative new resources for manufacturing new drugs against newly evaluating diseases.

Pharmacognostic, Phytochemical, Physico-chemical Standardization of Casuarina equisetifolia Stem-Inner bark

2021 ◽  
pp. 193-199
Author(s):  
Archana R. Pawar ◽  
Priya S. Rao ◽  
Dattaprasad N. Vikhe
Keyword(s):  
Herbal Medicine ◽  
Aqueous Extract ◽  
Pharmacological Activity ◽  
Chemical Constituents ◽  
Herbal Medicines ◽  
Herbal Product ◽  
Ethanol Extract ◽  
Casuarina Equisetifolia ◽  
Inner Bark ◽  
Physico Chemical

Over three thousand years in India, the Ayurvedic system of medicine has been in use. The phytomedicine, which is modernized method of formulating different kinds of herbal medicines, has yielded a new herbal product as well as new system of herbal medicine. The plant Casuarina equisetifolia is evergreen tree; belongs to family Casuarinaceae generally, attain height up to 50 m, introduced into India. The presence of different chemical constituents responsible for pharmacological activity such as analgesic, anti-inflammatory, Anti-histaminic, Wound healing. This research article highlighted Pharmacognostic account as well as physico-chemical evaluation, which shows how it will effective in the treatment of disease and disorder using herbal medicine. In addition to that, the Stem-inner bark of Casuarina equisetifolia is phytochemically evaluated using three different extract of Casuarina equisetifolia such as Methanol, Ethanol and Aqueous extract to show which secondary metabolites are present and result is that Methanol extract shows maximum Phenol, Tannin, flavonoid and Terpenoid content followed by Ethanol extract and then aqueous extract so that one can conclude stem-inner bark of Casuarina equisetifolia responsible for different pharmacological activity.

scholarly journals Ethical issues in traditional herbal medical practice in Nigeria

2019 ◽  
Vol 2 (4) ◽  
pp. 129-135
Author(s):  
Ezedike Edward ◽  
Chrisantus Kanayochukwu Ariche
Keyword(s):  
Health Care ◽  
Herbal Medicine ◽  
Ethical Issues ◽  
Herbal Medicines ◽  
World Health ◽  
Health Care Ethics ◽  
Traditional Herbal Medicine ◽  
Economic Issues ◽  
Synthetic Drugs ◽  
Health Organization

There is increased use and popularity of herbal medicine in Nigeria in recent times. Scholars from different fields have attributed this recent upsurge to economic issues, high cost of modern medical care, loss of confidence in synthetic drugs, resistant of diseases to some modern drugs and easy accessibility of herbal medicines and its practitioners, amongst others. According to the World Health Organization (WHO), a large portion of the world’s population patronizes traditional herbal medicines. However, there is perceived neglect of the core principles of health care ethics by the practitioners and marketers of traditional herbal medicine in Nigeria. This is worrisome. In this connection, this paper argues that Nigerians will benefit immensely from traditional herbal medicine if its practitioners and marketers observe and respect these core principles of health care which includes the principles of beneficence, non-maleficence, autonomy, informed consent, justice, and truthfulness. This study is purely qualitative and adopts a textual critical analytic method.

scholarly journals Herbal Medicine for the Treatment of Rheumatoid Arthritis

2020 ◽  
pp. 1-4
Author(s):  
A Krishna Sailaja ◽  
◽  
E Veena Rani ◽  
Swetha Swetha ◽  
◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Immune System ◽  
Autoimmune Disease ◽  
Herbal Medicine ◽  
Herbal Medicines ◽  
Stem Bark ◽  
Synthetic Drugs ◽  
Hands And Feet ◽  
Toxic Reactions ◽  
Arthritis Rheumatoid

The main aim of this article is to reduce the adverse effects associated with synthetic drugs which are used to reduce the inflammation in rheumatoid arthritis. Rheumatoid arthritis is defined as a chronic inflammatory disorders affecting many joints, including those in the hands and feet. It is an autoimmune disease in which the body’s immune system (which normally protects the health from foreign substances like bacteria and viruses will mistakenly attacks the joints). The greatest disadvantage of the presently available potent synthetic drugs lies in their toxic reactions and reappearance of symptoms after discontinuation.To overcome this effects herbs/herbal based preparation are used to treat rheumatoid arthritis. Herbal medicines will act as parcels to human inorder to combat disease from the dawn of civilization. Some of the natural herbs which shows anti-rheumatic action are-vatariguggul, terpenes, stem bark of ficusbengalensis, punarnava etc

Musikalisasi Syi’ir Aqoid Kiai Zaini Mun’im dan Budidaya Tanaman Obat Keluarga (Toga) di Pesantren Nurul Jadid Probolinggo

2020 ◽  
Vol 1 (1) ◽  
pp. 47-58
Author(s):  
Khodijatul Qodriyah
Keyword(s):  
Herbal Medicine ◽  
Herbal Medicines ◽  
Successful Implementation ◽  
Short Term ◽  
Middle Term

The lack of students’ knowledge of their teachers’ works and the less of their consciousness to the environment are crucial problems in some islamic boardingschool, especially in Nurul Jadid. These issues will be settled by implementation of religious preaching (dakwah) with poem (syi’ir) in Syu’abul Iman of Kiai Zaini Mun’im and prefentive action to the illness through herbal medicines of family crops medicine (tanaman obat keluarga). The program is undertaken with some phases, including planting family crops medicine, making herbal medicines, musicalisation of poem in book of Syu’abul Iman, socialization of the herbal medicine and musical poem of Syu’abul Iman. These phases have been structured with long-term, middle-term, and short-term programs which were finished during approximately 4 months (Augustus – November 2019). The involvement of many parties, such as activists of environment in Nurul Jadid, has strongly influenced on the successful implementation of these programs.Keywords: Family Crops Medicine, Nurul Jadid Islamic Boardingschool, Book of Syu’abul Iman

Ethanol Extract Of Centella Asiatica (L.) Urban Leaves Effectively Inhibit Streptococcus pyogenes and Pseudomonas aeruginosa by Invitro Test

2020 ◽  
Vol 2 (2) ◽  
pp. 69-76
Author(s):  
Dini Aulia Azmi ◽  
Nurlailah Nurlailah ◽  
Ratih Dewi Dwiyanti
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Streptococcus Pyogenes ◽  
Bacterial Infections ◽  
Herbal Medicines ◽  
Centella Asiatica ◽  
Ethanol Extract ◽  
Dilution Method ◽  
Initial Stage ◽  
Independent Variable

Streptococcus pyogenes and Pseudomonas aeruginosa are some of the causes of infectious diseases. Centella asiatica (L.) Urban has many benefits for humans, including overcoming fever, anti-bacterial, and anti-inflammatory. This study aims to determine the inhibition of Centella asiatica (L.) Urban leaves ethanol extract on the growth of Streptococcus pyogenes and Pseudomonas aeruginosa. This research is the initial stage of the development of herbal medicines to treat Streptococcus pyogenes and Pseudomonas aeruginosa infections. The independent variable was the concentration of ethanol extract of Centella asiatica (L.) Urban leaves and the dependent variable was the growth of Streptococcus pyogenes and Pseudomonas aeruginosa. The anti-bacterial activity test was carried out by the liquid dilution method. The concentrations used are 20%, 40%, 60%, 80%. 100% The results showed that the minimum inhibitory concentration (MIC) against Streptococcus pyogenes: 40% and Pseudomonas aeruginosa: 40%. Minimum bactericidal concentration (MBC) results for Streptococcus pyogenes: 60% and Pseudomonas aeruginosa: 60%. So it can be concluded that there is inhibition of the ethanol extract of Centella asiatica (L.) Urban leaves on the growth of Streptococcus pyogenes and Pseudomonas aeruginosa. Centella Asiatica (L.) Urban extract has potential as herbal medicine against bacterial infections but requires further research to determine its effect in vivo.

Nano Phytomedicine Based Delivery System for CNS Disease

2020 ◽  
Vol 21 (9) ◽  
pp. 661-673 ◽  
Author(s):  
Mohammed Asadullah Jahangir ◽  
Chettupalli Anand ◽  
Abdul Muheem ◽  
Sadaf Jamal Gilani ◽  
Mohamad Taleuzzaman ◽  
...  
Keyword(s):  
Herbal Medicine ◽  
Low Cost ◽  
Herbal Medicines ◽  
Herbal Drugs ◽  
Widespread Acceptance ◽  
The Central Nervous System ◽  
Low Toxicity ◽  
Ancient Times ◽  
Plant Sources ◽  
Herbal Formulations

Herbal medicines are being used since ancient times and are an important part of the alternative and traditional medicinal system. In recent decades, scientists are embracing herbal medicines based on the fact that a number of drugs that are currently in use are derived directly or indirectly from plant sources. Moreover, herbal drugs have lesser side effects, albeit are potentially strong therapeutic agents. The herbal medicine market is estimated to be around US $62 billion globally. Herbal medicine has gained widespread acceptance due to its low toxicity, low cost, ease of accessibility and efficacy in treating difficult diseases. Safety and efficacy are another important factors in the commercialization process of herbal medicines. Nanotechnology has been shown to be potentially effective in improving the bioactivity and bioavailability of herbal medicines. Development of nano-phytomedicines (or by reducing the size of phytomedicine), attaching polymers with phytomedicines and modifying the surface properties of herbal drugs, have increased the solubility, permeability and eventually the bioavailability of herbal formulations. Novel formulations such as niosomes, liposomes, nanospheres, phytosomes etc., can be exploited in this area. This article reviews herbal medicines, which have prominent activity in the Central Nervous System (CNS) disorders and reported nano-phytomedicines based delivery systems.

Herbal Medicine: Clinical Perspective & Regulatory Status

2020 ◽  
Vol 23 ◽  
Author(s):  
Md Abul Barkat ◽  
Anjali Goyal ◽  
Harshita Abul Barkat ◽  
Mohammad Salauddin ◽  
Faheem Hyder Pottoo ◽  
...  
Keyword(s):  
Herbal Medicine ◽  
Herbal Medicines ◽  
New Drugs ◽  
Herbal Drugs ◽  
Clinical Perspective ◽  
Regulatory Status ◽  
Novel Drugs ◽  
History Of ◽  
Pros And Cons ◽  
Health Complications

Abstract:: Herbal medicines pays an important in treating the vaious diseases mainly due to the their potentially high therapeutic values and also due to the better acceptance of vaioruspatient under different health complications. The herbal medicine practice involves use of part of plant, entire plant or the selectctive isolated phytomedicineand the use and practices based on these has its pros and cons and has been greatly affected during the dawn. The search of new drugs during scientific era revives the interest in discovery of herbal drugs from different natural resources during 20th century. The present modern healthcare system invovlves utilization drugs and 50% of them are of ofnaural origin. Herbal drug disocovery found to be highly costly affair with low success rate and it hinders the further progress in utilizting the phytomedicine in treating the various deseases. But in recent years there is an increase in the search interest of herbal drugs mainly by the pharmaceutical industry and those invoves in the search of novel drugs from the herbs. Discovery of such new novel phytomedicines has to overcomes various challenges in indentification of active extracts and their toxicity, advereffects, herb drug interaction and importantly their regulatory requirments. The present review mainly focused on the history of herbal medicine, current clinical perspective, pharmaceutical, and regulatory challenges as well as its clinical presentation. Moreover, problems encountered in drug discovery from herbal resources and its possible solutions are delineated.

The Effects of Herbal Medicines on Women Sexual Dysfunction: A Systematic Review

2020 ◽  
Vol 17 ◽  
Author(s):  
Tahereh Molkara ◽  
Maliheh Motavasselian ◽  
Farideh Akhlaghi ◽  
Mohammad Arash Ramezani ◽  
Hamideh Naghedi Baghdar ◽  
...  
Keyword(s):  
Sexual Dysfunction ◽  
Herbal Medicine ◽  
Sexual Health ◽  
Sexual Function ◽  
Psychological Health ◽  
Health Management ◽  
Herbal Medicines ◽  
Physical And Psychological Health ◽  
Female Sexual Response

: Sexual health plays an important role in the women’s health and quality of life. Sexual health management is a prerequisite for physical and psychological health of women. Sexual desire, arousal, and orgasm are three factors of female sexual response. So far many different methods has been known for the treatment of female sexual dysfunction, however none of them are not an efficacious therapy. Generally, use of herbal medicine is a safe and effective therapeutic method in the treatment of women with sexual dysfunction. The role of herbal and nutritional supplementation in female sexual function has attracted researchers’ interest in recent years. This study aimed to the evaluation of the studies focusing on the herbal medicine on women sexual function and the assessment of its effectiveness.

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