Effects of Smoking and Lipid Profile of the Patient on the Onset and Maintenance of Periodontal Disease

2018 ◽  
Vol 69 (10) ◽  
pp. 2648-2651
Author(s):  
Gabriela Ciavoi ◽  
Alina Tirb ◽  
Edwin Sever Bechir ◽  
Farah Bechir ◽  
Ilinca Suciu
Keyword(s):  
Periodontal Disease ◽  
Hdl Cholesterol ◽  
Group Iv ◽  
Control Group ◽  
Mean Values ◽  
Group Iii ◽  
Group I ◽  
Significant Difference ◽  
And Control ◽  
Dental Plaque Index

The purpose of our study is to determine the correlation between the effects of smoking, triglycerides and cholesterol (total, HDL, LDL) and periodontal disease. 90 patients, smokers diagnosed with periodontal disease and 30 nonsmoker patients (control group), in the age of 30-60 years, were studied. Patients were divided into 4 groups, each of 30 patients as follows: group I - smokers up to 10 cigarettes a day, group II-smokers between 10-20 cigarettes a day, group III-over 20 cigarettes a day, group IV- control group, nonsmokers. The values of the Silness-Loe dental plaque index (DPI), the gingival bleeding index (GI), the Periodontal Disease Index (PDI) -Ramfjord were noted in both the examined and control groups. The values of total cholesterol and HDL cholesterol showed statistically significant difference between the mean values �in the examined groups, while mean values �of HDL cholesterol in the second and third examined subgroups and control group were in higher range than the normal one. We concluded also that there is a relationship between smoking, the number of cigarettes smoked and the periodontal disease.

scholarly journals The effects of astaxanthin on salivary gland damage caused by cisplatin in the rat

2017 ◽  
Vol 5 (4) ◽  
pp. 1410
Author(s):  
Suat Terzi ◽  
Abdulkadir Özgür ◽  
Tolga Mercantepe ◽  
Metin Çeliker ◽  
Levent Tümkaya ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Submandibular Gland ◽  
Cell Density ◽  
Group Iv ◽  
Control Group ◽  
Group V ◽  
Group Iii ◽  
Significant Difference ◽  
The Mean ◽  
And Control

Background: Cisplatin is a potent antineoplastic agent widely used for a variety of malignancies. However, it has many dose-limiting side effects such as neurotoxicity, cytotoxicity and ototoxicity. The aim of our study was to determine the effectiveness of astaxanthin (ASX) as a cytoprotective agent against cisplatin-induced cytotoxicity in the submandibular glands of rats.Methods: Thirty-six adult male Wistar albino rats were divided into six groups as follows: group I: saline control; group II: 75 mg/kg/day ASX; group III: 16 mg/kg cisplatin; group IV: 25 mg/kg/day ASX + cisplatin; group V: 75 mg/kg/day ASX + cisplatin; group VI: olive oil + cisplatin. In all groups, submandibular gland histopathological and histochemical investigations were done using a light microscope. Every rat section was semi-quantitatively scored. Neutrophil infiltration density, myoepithelial cell density in the degeneration area, degenerative granular duct cell density, degenerative seromucous acinus cell density, and changes in the content of the secretory granules of seromucous acini and granular ducts of the parenchyma and stroma were calculated.Results: The results of the analysis of the mean acinus area of the submandibular gland revealed that there was a significant decrease in cisplatin group rats when compared to control rats (p<0.05, p=0.00). However, there was no significant difference between-group IV, V and control group in terms of mean acinus area. (p=0.541, p=0.773). The results of the analysis of the mean ducts area of the submandibular gland also showed that there were significant increased group III compared to control rats (p<0.05, p=0.031). There was no significant difference between-group IV, V and control group in terms of mean ducts area (p>0.05, p=0.921). Similarities were observed in the mean ducts area with the group IV and the group V (p>0.05, p=0.571).Conclusions: These results suggest the possibility that the clinical use of ASX could reduce or prevent damage to the salivary gland of patients receiving cisplatin chemotherapy.

scholarly journals Role of Vitamin D in Near Sightedness

2020 ◽  
Vol 36 (2) ◽  
Author(s):  
Yasir Iqbal Malik ◽  
Aqsa Malik ◽  
Rabbia Shabbir ◽  
Atteaya Zaman ◽  
Sohail Zia ◽  
...  
Keyword(s):  
Vitamin D ◽  
Sampling Technique ◽  
Control Group ◽  
Mean Values ◽  
Group I ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
Azad Kashmir ◽  
And Control

Purpose: To determine the levels of Vitamin D in children with myopia and to compare them with age matched controls. Study Design:  Case control study. Place and Duration of Study:  The study was conducted in Naseer Memorial Hospital, Dadhyal Azad Kashmir from March 2016 to March 2017. Material and Methods:  Two hundred patients were selected using convenient sampling technique and were divided two groups (group I Myopic and group II control). Myopia was labeled if after subjective refraction a Spherical Equivalent (SE) of −0.50 diopters (D) or more was found. Vitamin D levels were measured by radioimmunoassay technique with Diasorin SR® kit following the user’s manual. Vitamin D levels less than 20 ng/ml were considered Vitamin D deficient following the standards of American academy of pediatrics. The collected data was entered in the statistical package for social sciences (SPSS) version 21 for analysis. Independent t–test was used to determine the significant difference of means between controls and patients. P-values less than 0.05 were considered significant. Results:  Mean age of controls and myopes were 10.65 ± 3.9 and 10.20 ± 2.5 years respectively. Vitamin D levels in myopic children were found to be 14.95 ± 3.75 ng/ml and there was no significant difference in mean values of Vitamin D levels in myopic and control group. Conclusion:  We found no difference in Vitamin D levels of myopic and non myopic children and concluded that Vitamin D has no role in development or progression of myopia.

scholarly journals An in vitro comparative Evaluation of Fracture Strength of Roots Instrumentated with Self-adjusting File and Reciproc Reciprocating File, with and without Obturation

2017 ◽  
Vol 1 (1) ◽  
pp. 20-25
Author(s):  
Pooja Kabra
Keyword(s):  
Fracture Strength ◽  
Comparative Evaluation ◽  
Group Iv ◽  
Control Group ◽  
Group V ◽  
Group Iii ◽  
Group I ◽  
Significant Difference ◽  
Group Ii

ABSTRACT Aim The purpose of this study was to evaluate the fracture strength of roots instrumented with the self-adjusting file (SAF; ReDent-Nova, Ra'anana, Israel) and the Reciproc reciprocating file and that were and were not obturated using the warm vertical lateral compaction technique. Materials and methods In total, 75 mandibular premolar teeth were sectioned at or below the cementoenamel junction to obtain roots 13 mm in length. The roots were balanced with respect to buccolingual and mesiodistal diameters and weight. They were distributed into four experimental groups and one control group (n = 15): No instrumentation (group I), instrumentation with SAF files but no obturation (group II), instrumentation with SAF files and obturated with warm vertical lateral compaction (group III), instrumentation with Reciproc File but no obturation (group IV), and instrumentation with Reciproc File and obturated with warm vertical lateral compaction (group V). AH Plus sealer (Dentsply DeTrey, Konstanz, Germany) was used along with gutta-percha points. One week later, a vertical load was applied to the specimen's canal until fracture occurred. Data were statistically analyzed using one-way analysis of variance (p = 0.05). Results The mean fracture load was 312.83 N for group I, 297.35 N for group II, 359.15 N for group III, 231.51 N for group IV, and 275.81 N for group V. Conclusion The fracture resistances exhibited a statistically significant difference between all the groups. Teeth instrumented by SAF exhibited a better fracture resistance. How to cite this article Tyagi S, Choudhary E, Kabra P, Chauhan R. An in vitro comparative Evaluation of Fracture Strength of Roots Instrumentated with Self-adjusting File and Reciproc Reciprocating File, with and without Obturation. Int J Clin Dent Res 2017;1(1):20-25.

A Clinical Evaluation of Deproteinization and Different Cavity Designs on Resin Restoration Performance in MIH-Affected Molars: Two-Year Results

2017 ◽  
Vol 41 (5) ◽  
pp. 336-342 ◽  
Author(s):  
Hayriye Sönmez ◽  
Sinem Saat
Keyword(s):  
Group Iv ◽  
Retention Rates ◽  
Control Group ◽  
Clinical Effects ◽  
Success Rates ◽  
Group Iii ◽  
Group I ◽  
Molar Incisor Hypomineralization ◽  
Significant Difference ◽  
Group Ii

Background: The aim of this study was to evaluate the clinical effects of deproteinization of the hypomineralized enamel and different cavity designs on the performance of the composite resin restorations(CRRs) placed into the cavities of MIH (molar incisor hypomineralization)-affected molars. Study design: 95 MIH-affected permanent first molars (PFMs) and 31 caries but not MIH-affected PFMs (126 teeth in total) were included in the study. The MIH-affected molars were divided into three groups. In Group I, all hypomineralized tissue was removed until healthy enamel was reached. In Group II, carious and cheesy hypomineralized tissue was removed until a reasonable resistance was detected in the hypomineralized tissue. In Group III, cavities designed as Group II, differently from this group deproteinization of the left hypomineralized tissue was performed prior to the placement of CRRs. Group IV served as the control group consisting of unaffected carious PFMs. Restorations were evaluated according to modified USPHS criteria for 24 months. Results: The retention rates were 93.7% for Group I, 80.7% for Group II, 93.5% for Group III and 100% for Group IV. The success rate for the restorations in Group II proved significantly lower (p&lt;0.05) than that of the other three groups. No significant difference in success rates was observed between Group I, Group III and Group IV (p&gt;0.05) at the end of 24 months. Conclusions: Failure of the restorations was predominant in the group that the hypomineralized tissue was left surrounding the cavities. Deproteinization of the hypomineralized enamel was found to enhance the retention rates of CRRs.

scholarly journals Microhardness and Fracture Resistance of Radicular Dentin Treated with Different Concentrations of Calcium Hydroxide in Endodontic Regeneration Procedures

2021 ◽  
Vol 9 (D) ◽  
pp. 324-329
Author(s):  
Sara N. Hashem ◽  
Maha Adel Elhousiny
Keyword(s):  
Calcium Hydroxide ◽  
Root Canal ◽  
Fracture Resistance ◽  
Control Group ◽  
Group Iii ◽  
Group I ◽  
Significant Difference ◽  
Endodontic Regeneration ◽  
And Control ◽  
Control Group Group

Purpose: to reveal the effect of different concentrations of prepared calcium hydroxide pastes (70%, 50%, and 30%) used in regenerative endodontic on microhardness and fracture resistance of radicular dentin. Material and methods: Different concentrations of calcium hydroxide (Ca(OH)2) were prepared with measured pH, then forty eight single rooted teeth were prepared and randomized into three groups according to Ca(OH)2 paste concentrations (12 samples each) and 12 samples were availed as control group. Group I: root canal contained 30% Ca(OH)2 paste. Group II: root canal contained 50% Ca(OH)2 paste. Group III: root canal contained 70% Ca(OH)2 paste. Samples were stored at 37 0C with 100% humidity for four weeks for subsequent microhardness and fracture resistance tests. Results: There was a statistically significant reduction of microhardness  and fracture resistance between test groups and control group (P≤ 0.05), group III showed a  significant reduction  in both microhardness and fracture resistance compared to group I. However, there was no significant difference in pH between different concentration of Ca(OH)2. Conclusion: Increasing concentration of Ca(OH)2 paste can negatively affect microhardness and fracture resistance of radicular dentin in revascularization procedure.

scholarly journals Evaluation of Serum Fibrinogen, Plasminogen,α2-Anti-Plasmin, and Plasminogen Activator Inhibitor Levels (PAI) and Their Correlation with Presence of Retinopathy in Patients with Type 1 DM

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Sefika Burcak Polat ◽  
Nagihan Ugurlu ◽  
Fatma Yulek ◽  
Huseyin Simavli ◽  
Reyhan Ersoy ◽  
...  
Keyword(s):  
Plasminogen Activator Inhibitor ◽  
Group Iv ◽  
Control Group ◽  
Positive Correlation ◽  
Group Iii ◽  
Group I ◽  
And Control ◽  
Type 1 Dm ◽  
Activator Inhibitor

Background.Diabetic retinopathy (DR) is the leading cause of blindness in the world. Retinopathy can still progress despite optimal metabolic control. The aim of the study was to determine whether different degrees of DR (proliferative or nonproliferative) were associated with abnormally modulated hemostatic parameters in patients with T1DM.Method.52 T1DM patients and 40 healthy controls were enrolled in the study. Patients were subdivided into three categories. Group I was defined as those without retinopathy, group II with NPRP, and group III with PRP. We compared these subgroups with each other and the control group (Group IV) according to the serum fibrinogen, plasminogen, alpha2-anti-plasmin (α2-anti-plasmin), and PAI.Results. We detected that PAI-1, serum fibrinogen, and plasminogen levels were similar between the diabetic and control groups (P=0.209,P=0.224, andP=0.244, resp.), whereasα2-anti-plasmin was higher in Groups I, II, and III compared to the control group (P<0.01,P<0.05, andP<0.001, resp.). There was a positive correlation between serumα2-anti-plasmin and HbA1c levels (r=0,268,P=0.031).Conclusion. To our knowledge there is scarce data in the literature aboutα2-anti-plasmin levels in type 1 diabetes. A positive correlation betweenα2-anti-plasmin with HbA1c suggests that fibrinolytic markers may improve with disease regulation and better glycemic control.

Effect of progesterone and oxytocin on conception rate in repeat breeding Cattle

2017 ◽  
Vol 2 (01) ◽  
pp. 43-46
Author(s):  
Dinesh Mahto
Keyword(s):  
Group Iv ◽  
Conception Rate ◽  
Control Group ◽  
Group V ◽  
Group Iii ◽  
Group I ◽  
Hydroxyprogesterone Caproate ◽  
The Difference ◽  
Rectal Palpation ◽  
And Control

A total of 50 cross bred repeat breeder cattle were selected and grouped into 4 treatment and one control group which belonging to organized farms around, K. V. K. Gandhar, Jehanabad. Hydroxyprogesterone caproate (500 mg) was administered I.M. on day 4 post A. I. in group I, In group II, 500mg progesterone was administered I M on day 4 and again on day 10. Evatocin (40 I.U.) was administered I.M. 5 minutes before A.I. to animals belonging to group III. The same drug was used through Intra vulvo-submucosal route (15 I.U.) to animals of group IV. Group V animals received no treatment and served as control. Pregnancy diagnosis was done by rectal palpation D 45-60 after artificial insemination. In group I, the conception rate was found to be 60% as against 20 % in the control (Non-significant), Gr II, the conception rate improved from 20% in control animals to 70% in treated animals (Significant) and Gr III, the C.R. 60% than control(20%) where as Gr IV, C.R. 40% . The difference in conception rate of treatment and control group animals was non-significant.

Efficacy of Ovsynch and Ovsynch Plus Protocol for Improvement of Fertility in Postpartum Sahiwal Cows

2019 ◽  
Vol 14 (04) ◽  
Author(s):  
J. P. Lakher ◽  
M. K. Awasthi ◽  
J. R. Khan ◽  
M. R. Poyam
Keyword(s):  
Fixed Time ◽  
Conception Rate ◽  
Control Group ◽  
Group Iii ◽  
Treatment Groups ◽  
Group I ◽  
Early Postpartum ◽  
The Status ◽  
Sahiwal Cows ◽  
And Control

The present study was conducted to investigate the efficacy of Ovsynch and Ovsynch plus protocol in postpartum (day 60) Sahiwal cows (n=18). Animals were randomly divided into three equal groups, viz., Ovsynch group Ovsynch plus group and Control group. Animals of group I (n = 6) were treated with traditional Ovsynch protocol. The animals (n = 6) of group II were treated with Ovsynch plus protocol which consisted of an initial intramuscular injection of eCG (Folligon) @ 250 IU on day 60 postpartum followed 3 days later by GPG (Ovsynch) protocol. In group-III Control, no treatment was given to animals (n = 6). Treated animals were inseminated at a fixed time between 14 and 20 hrs after second GnRH injection, irrespective of estrus detection. Blood samples were collected from each animal on days 50 and 60 postpartum to determine the status of cyclicity in animals based on serum concentrations of progesterone (P4). A third blood sample was collected on the day of prostaglandin treatment to determine the response of first GnRH injection. Four animals each were cyclic, and two were acyclic in both treatment groups. Four animals each responded to first GnRH treatment in both treatment groups. Similarly, two animals each got conceived giving conception rate of 50% (2/4) in each treatment. In the control group, one out of 6 animals got conceived yielding 16.66 % conception rate (1/6) during the study period. It may be thus concluded that Ovsynch and Ovsynch plus protocol may be used during the early postpartum period to improve the reproductive efficiency in postpartum Sahiwal cows.

Analysis of surface conditioning methods on core-veneer bond strength of CAD/CAM zirconia restorations

2020 ◽  
pp. 1-11
Author(s):  
Anip K. Roy ◽  
Govind N. Prasad ◽  
Tushar V. Bhagat ◽  
Saurabh Chaturvedi ◽  
Vishwanath Gurumurthy ◽  
...  
Keyword(s):  
Electron Microscope ◽  
Bond Strength ◽  
Shear Bond Strength ◽  
Group Iv ◽  
Control Group ◽  
Group Iii ◽  
Surface Conditioning ◽  
Group I ◽  
Alumina Particles ◽  
Scanning Electron

BACKGROUND: The increased strength of zirconia has resulted in its widespread application in clinical dentistry. Nevertheless, the fracture of veneering porcelains remains one of the key reasons of failure. OBJECTIVE: The objective of this study was to compare and analyze the influence of surface conditioning methods on the core-veneer bond strength of zirconia restorations. METHODS: Thirty specimens of zirconia core with sizes 10 × 5 × 5 mm were layered with porcelain of sizes 5 × 3 × 3 mm. On the basis of different surface conditioning methods, four groups were made: Group I: abrasion with airborne alumina particles of 110 μm size, Group II: sandblasting with silica coated alumina particles of 50 μm in size, Group III (modified group): alteration with a coating of zirconia powder prior to sintering, and Group IV (control group): metal core specimens. The shear force of all specimens was tested using a universal testing machine with a 0.5 mm/min crosshead speed. One-way analysis of variance (ANOVA) and Tukey’s post hoc pair wise comparison (p= 0.05) were performed to analyze the shear bond strength. A scanning electron microscope was used to assess the fractured specimens. RESULTS: A statistically significant difference was noted between the groups. The mean value of shear bond strength was 40.25 MPa for Group I, 41.93 MPa for Group II, 48.08 MPa for Group III and 47.01 MPa for Group IV. CONCLUSIONS: The modified zirconia group and control group demonstrated a significantly higher mean bond strength than that of Group I, where airborne particle abrasion was used. The scanning electron microscope showed that cohesive fracture in the porcelain veneers was the main problem of failure in altered zirconia. The modified zirconia specimens in Group III demonstrated significantly improved values of shear bond strength.

A Study on the Effect of Samoa Extract (Cleome droserifolia) on Sperm Quality in Male Albino Rats Exposed to Pyrethroid

2021 ◽  
pp. 39-45
Author(s):  
Nura I. Al-Zail ◽  
Salah F. Kamies
Keyword(s):  
Sperm Quality ◽  
Group Iv ◽  
Male Rats ◽  
Control Group ◽  
Albino Rats ◽  
Protective Agent ◽  
Group V ◽  
Group Iii ◽  
Group I ◽  
Induced Changes

Pyrethroid cyhalothrin (PC) is an insecticide that is used worldwide for pest control in agriculture and household use. Samoa extract (SE) is a potent antioxidant protecting cells from oxidative stress. The present study investigates the protective and therapeutic effect of SE on PC-induced changes in sperm quality in male rats. Fifty adult male albino rats were divided into five groups: group I: served as control; group II: received PC i.p. only (6.2 mg/kg b.wt.); group III: received SE only (100 mg/kg b.wt., p.o.) for eight weeks; group IV: received SE as a protective agent daily for eight weeks, then followed by the administration of PC (i.p.) three times a week for two weeks; group V: exposed to PC (i.p.) three times a week for two weeks, then treated with the SE daily for 8 weeks. Results showed that PC caused markedly impaired sperm quality (a count, viability, motility, and abnormality). Compared to PC-treated animals, SE in the protective group markedly restored the alteration of sperm indices. However, SE in the curative group was found to be less effective in restoring PC-induced alterations. In conclusion, the data of this study revealed that the SE as a protective agent is more effective than as a therapeutic agent. Keywords: Samoa; Pyrethroid; Sperm quality; Rat

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