scholarly journals Influence of Environmental Factors on Rhinosinusal Tumours

2019 ◽  
Vol 70 (5) ◽  
pp. 1818-1821
Author(s):  
Razvan Hainarosie ◽  
Eugenia Maria Domuta ◽  
Mihail Tusaliu ◽  
Marius Gabriel Dabija ◽  
Florin Anghelina ◽  
...  

Cancer of the nasal cavity and paranasal sinuses is a rare malignancy. The tumours of the nasal cavity are thus associated with the maxillary and ethmoidal sinuses. Those that start from the nasal vestibule and nasal septum raise particular problems and, although rare, form a particular group of cases among the rhinosinusal tumours. Radiation exposure, viral infections and constitutional factors were associated with the occurrence of rhinosinusal neoplasia also, but the evidence is inconclusive and indicates that only a small proportion of all squamous carcinomas can be attributed. The purpose of this study is the complex retrospective analysis of the cases of rhinosinusal malignancies diagnosed and treated in the Otolaryngology Clinic of the St. Spiridon Emergency Clinical Hospital in Iasi. We evaluated the characteristics of the patient group using a statistically significant analysis of the age, gender, background, and factors of affiliation. Specific tests and indicators have been used. It is not to be neglected the effects of the poor economic conditions andthe lack of education of the population, by postponing the moment of presentation tophysician, influencing the therapeutic decision, postoperative evolution. Thesepatients often present different degrees of malnutrition,immunodepression, etc. Statistical processing showed that thesepatients have a twofold risk of developing rhinosinusal tumours.

Author(s):  
Arwa Kurabi ◽  
Kwang Pak ◽  
Adam S. DeConde ◽  
Allen F. Ryan ◽  
Carol H. Yan

AbstractViral infections have already been implicated with otitis media and sudden sensorineural hearing loss. However, the pathophysiology of COVID-19 as it relates to otologic disorders is not well-defined. With the spread of SARS-CoV-2, it is important to evaluate its colonization of middle ear mucosa. Middle ear and nasal tissue samples for quantitative RT-PCR and histologic evaluations were obtained from post-mortem COVID-19 patients and non-diseased control patients. Here we present evidence that SARS-CoV-2 colonizes the middle ear epithelium and co-localizes with the primary viral receptor, angiotensin-converting enzyme 2 (ACE2). Both middle ear and nasal epithelial cells show relatively high expression of ACE2, required for SARS-CoV-2 entry. The epithelial cell adhesion molecule (EpCAM) was use as a biomarker of epithelia. Furthermore, we found that the viral load in the middle ear is lower than that present in the nasal cavity.


2020 ◽  
Vol 13 (08) ◽  
pp. 2050169
Author(s):  
Iveta Nikolova ◽  
Anka Markovska ◽  
Mikhail Kolev

Nowadays autoimmune diseases are widely distributed. More than 80 illnesses are included into this group of conditions. Their causes are not clear exactly, but it is believed that among them are genetic factors, viral infections, socio-economic conditions, etc. We propose a new mathematical model describing a general autoimmune disease in order to analyze some mechanisms of autoimmune disorders. The model is a system of ordinary differential equations. We perform preliminary qualitative analysis of the model as well as propose an algorithm for numerical simulations. Some results of our numerical experiments are presented and commented from a biological point of view.


2019 ◽  
Vol 35 (1) ◽  
pp. 96-111 ◽  
Author(s):  
Alex Waddan

AbstractThere has been a growing discussion in recent years about rising inequality in the U.S. Yet, this discourse, in focusing on the fortunes of the top 1%, distracted attention from the design of policy initiatives aimed at improving socio-economic conditions for the poor. This paper examines the development of anti-poverty politics and policy in the US during the Obama era. It analyses how effective the strategies and programmes adopted were and asks how they fit with models of policy change. The paper illustrates that the Obama administration did adopt an array of anti-poverty measures in the stimulus bill, but these built on existing programmes rather than create new ones and much of the effort was stymied by institutional obstacles. The expansion of the Medicaid program, which was part of the ACA, was also muted by institutional opposition, but it was a more path breaking reform than is often appreciated.


2014 ◽  
Vol 14 (2) ◽  
pp. 168-187 ◽  
Author(s):  
Aulia Nabila ◽  
Elda L. Pardede

AbstractThis paper aims to analyze the effect of poverty on migration by using the IFLS 2000 and 2007 data. The results of binary and multinomial logistic regressions on all adults, adults in urban areas, and adults in rural areas show that the poor are less likely to migrate than the non-poorexcept for the case of urban to urban migration, where the poor are more likely to migrate than the non-poor. The results for other economic characteristics such as total value of assets and land ownership for farming consistently show that better economic conditions lower the probability to migrate.Keywords: Poverty, Migration, Urban Migration, Rural Migration, IFLS AbstrakStudi ini bertujuan untuk menganalisis pengaruh kemiskinan terhadap migrasi dengan menggunakan sampel individu 15 tahun ke atas dari data Survei Aspek Kehidupan Rumah Tangga Indonesia (SAKERTI) tahun 2000 dan 2007. Hasil regresi logistik biner dan multinomial menunjukkan bahwa untuk semua individu, baik individu di perkotaan maupun di perdesaan, peluang orang miskin untuk bermigrasi lebih kecil daripada yang tidak miskin. Namun, untuk individu di perkotaan, ditemukan bahwa peluang orang miskin untuk bermigrasi dari perkotaan ke perkotaan lebih besar dibanding yang tidak miskin. Hasil regresi untuk karakteristik ekonomi lainnya seperti total nilai aset dan kepemilikan lahan pertanian menunjukkan bahwa kondisi ekonomi yang lebih baik menurunkan probabilitas bermigrasi.Kata kunci: Kemiskinan, Migrasi, Migrasi Perkotaan, Migrasi Perdesaan, SAKERTI


Polar Record ◽  
1955 ◽  
Vol 7 (51) ◽  
pp. 467-485 ◽  
Author(s):  
E. J. C. Kendall

Scurvy was known from the earliest times as a condition likely to arise when men were constrained to live upon a limited diet because of crop failure, siege or extended voyaging. It was first clearly described in the thirteenth century but, although its connexion with restricted supplies and especially with paucity of vegetables and fruit in the diet, was recognized from that period, its occurrence was ascribed to many other factors. Thus, because it often affected many members of a closed community at about the same time, it was thought to be contagious; and although conditions such as cold, the diminution of daylight in polar regions and the constant humidity of sea voyages were the reason for lack of fresh fruits and vegetables, these conditions themselves were suggested as causes of the disease. Likewise poverty, resulting in overcrowding and insanitary conditions, was blamed, whilst in reality economic conditions prevented the poor from buying antiscorbutic foods.


2018 ◽  
Vol 15 (6) ◽  
pp. 54-64
Author(s):  
L V Luss ◽  
S V Tsarev ◽  
V I Astafurov ◽  
O I Sidorovich ◽  
M F Nikonova ◽  
...  

Aim. To study cellular and humoral immunological parameters of the employees of production sites located at the former mining and uranium ore processing territories. Materials and methods. In this work the clinical laboratory and immunological methods of examination were used. Statistical processing of the results was performed by using nonparametric analysis methods in the StatSoft Statistica 6 software package. Results. 101 employees of Chepetskiy mechanical plant were examined at the age of 19-62. 76 (75.2%) of them contacted with industrial factor, 64 - with radiation and 12 - with chemical. 25 (24.8%) employees had no contact with industrial factor. The immunological examination of the employees in contact with industrial factor revealed laboratory signs of imbalance in the immune system with IgE-overproduction. The risk group for secondary immunodeficiency with the leading infectious syndrome was 15.8%. Conclusion. Changes of cellular and humoral parameters on average values were not revealed. Infectious syndrome - recurrent ETN viral infections (13.9%) and herpes virus infection (13.9%) prevailed in the structure of the employees of Chepetskiy mechanical plant. A statistically significant difference in the content (percentage and absolute) of CD16+ lymphocytes was found in the employees of Chepetskiy mechanical plant contacted with industrial factor. These results had no clinical significance, what can be considered as an adaptive response to the chemical factor.


INFERENSI ◽  
2020 ◽  
Vol 13 (2) ◽  
pp. 219-252
Author(s):  
Abdul Hamid ◽  
Riris Aishah Prasetyowati ◽  
Rio Trisasmita

This paper examines the Concept of Income Distribution in Islam through the Zakat Fund which is managed as a source of funds in improving better conditions in the socio-economic poor population in the fields of education, housing, and income to support the economic growth of West Java Province. This study uses a sample test through a quantitative method and real data to observe the correlation and potential contribution of zakat from Muslim residents who work in West Java region to the distribution of income of the poor population. For each observation variable, before-and-after regression and comparison tests are associated with the potential of zakat as a concept of the distribution of Sharia or Islamic income. Hypothesis testing of two means is used to obtain different observational results from the results of this study. There is significant diversity in the socio-economic conditions of the poor before and after the implementation of the concept of distribution of Sharia or Islamic income in West Java Province. Likewise, the hypothesis testing shows that Sharia or Islamic income distribution has a significant influence on socio-economic conditions in the fields of education, proper housing, and income of the poor population on the growth of the regional economy of West Java (GRDP). With the diversity of relationships and influences among socioeconomic variables, e.g. the income of poor people after the calculation of Zakat and improper housing with the distribution of income with the concept of Islam have opposite relationships. However, the unidirectional relationship occurs in the education on theeconomic growth of the West Java regional domestic. 


2021 ◽  
Vol 7 (2) ◽  
Author(s):  
Christina Dameria ◽  
Dewi Shinta Bratanata

Eating together is a culture that was born along with human civilization. Eating together becomes a symbol in both religious and cultural rituals. Christianity notes that eating together becomes a medium in spreading the gospel that Jesus and His disciples did. The symbolic meaning presented in the practice or culture of eating together is acceptance and fellowship. Acceptance is defined as a space to acknowledge the equality of fellow human beings, which creates a sense of solidarity. At the same time, the fellowship provides space to connect. In addition, eating together fulfills the body's physical needs for hunger and restores the freshness of the soul from fatigue. This article tries to connect symbols in eating together to present spirituality in viewing other creations, namely nature that has been damaged. Natural damage needs to be seen as a reality that must be faced and resolved t in the spirituality of eating together. Another creation is nature being the poor, oppressed, marginalized and sick. The solidarity presented in the moment of eating together becomes a new perspective in seeing the context of the destruction of nature and the awareness to build the disconnected interconnection of fellow creations.AbstrakMakan bersama merupakan budaya yang lahir seiring dengan peradaban manusia. Makan bersama menjadi simbol baik dalam ritual keagamaan maupun budaya. Kekristenan mencatat bahwa makan bersama menjadi sebuah media dalam mengabarkan Injil yang dilakukan Yesus dan para murid-Nya. Makna simbolik yang dihadirkan dalam ritual atau budaya makan bersama adalah penerimaan dan persekutuan. Penerimaan diartikan sebagai sebuah ruang untuk mengakui adanya persamaan terhadap sesama manusia yang menimbulkan rasa solidaritas. Sedangkan persekutuan memberikan ruang untuk saling terhubung satu dengan yang lain. Selain itu makan bersama tidak sekadar memenuhi kebutuhan fisik tubuh akan rasa lapar tetapi juga mengembalikan kesegaran jiwa akan rasa lelah. Artikel ini mencoba menghubungkan simbol-simbol dalam makan bersama untuk menghadirkan spiritualitas dalam memandang ciptaan lain yaitu alam yang telah rusak. Kerusakan alam perlu dipandang sebagai sebuah kenyataan yang harus dihadapi dan diselesaikan bersama dalam spiritualitas makan bersama. Ciptaan lain yaitu alam menjadi yang miskin, tertindas, tersingkir dan sakit. Solidaritas yang dihadirkan dalam momen makan bersama menjadi sebuah perspektif baru dalam melihat konteks kerusakan alam dan kesadaran untuk membangun interkoneksi sesama ciptaan yang terputus.


2021 ◽  
pp. 1866802X2110353
Author(s):  
Miguel Carreras ◽  
Sofia Vera ◽  
Giancarlo Visconti

Research suggests that the coronavirus pandemic disproportionately affected poor communities. However, relatively little is known about how this differential impact affected support for, and compliance with, COVID-19 lockdown policies. This article examines the relationship between socioeconomic inequalities and public opinion towards COVID-19 containment measures in Peru. Despite the strict quarantine measures adopted by the government of Peru, the country struggled to contain the spread of the disease. We designed and implemented a nationally representative survey in Peru and found that economically vulnerable sectors are more likely to oppose the quarantine and are more likely to defy the stay-at-home recommendations to leave home and go to work. Our contribution highlights that poor citizens’ housing and economic conditions can explain why the poor are more likely to react negatively to COVID-19 lockdown policies.


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