scholarly journals THE ROLE OF NUTRITION IN BRAIN DEVELOPMENT

2016 ◽  
Vol 65 (2) ◽  
pp. 150-154
Author(s):  
Dana-Teodora Anton-Paduraru ◽  
◽  
Ana Simona Drochioi ◽  
Oana Teslariu ◽  
◽  
...  
Keyword(s):  
Energy Supply ◽  
Necessary Conditions ◽  
Biologically Active ◽  
Early Prevention ◽  
Complex Processes ◽  
Natural Birth ◽  
The Impact ◽  
The Brain ◽  
Active Substances

The brain is an organ that functions harmoniously special only through a balanced intake of biologically active substances. The phrase “food for brain” expresses the important role of nutrition in the development and energy supply of the brain. There is a brief presentation of data on the development of the brain, the existence and functionality of the microbiome-gut-brain axis and the impact of the key nutrients in these complex processes. The authors concluded that nutritional assistance to the pregnant woman since the onset of pregnancy, the prophylaxis of prematurity, the early prevention of the gut microbiome of infant through encouragement of natural birth and breast-feeding are necessary conditions for the development of the brain.

Investigation of the impact of a balanced diet according to the method of alfitherapy on the human body

2021 ◽  
Author(s):  
I.V. Pronin
Keyword(s):  
Climatic Conditions ◽  
Biologically Active ◽  
Regenerative Processes ◽  
Balanced Diet ◽  
Living Things ◽  
High Concentrations ◽  
The Impact ◽  
The Brain ◽  
Complete Regeneration ◽  
Active Substances

In the late 1980s – early 1990s, General A.V. Shcherbakov and Professor I.V. Pronin, who participated in the creation of the Russian Rescue Corps, developed a new method for saving all living things during disasters, dangerous climatic conditions, deadly situations, using the latest developments of Professor I.V. Pronin, which have no analogues in the world and named it "Medicine of support in extreme situations". For civilians, this system, based on the intersection of microbiology, algology and herbal medicine, became known as Alphitherapy. Initially, the method was intended for special forces operating in rescue operations during man-made disasters, as well as disasters caused by natural disasters. Alphitherapy is a method of balanced nutrition of plant origin with biologically active substances of medicinal plants, algae, microorganisms due to a combination of essential oils and active substances in high concentrations. The composition of a balanced diet according to the method of alfitherapy includes a living bactericidal environment, which many times exceeds the therapeutic capabilities of drugs of chemical origin. Purpose of work – investigation of the effect of accelerating regenerative processes and a healing effect as a result of the use of a balanced diet according to the method of alfitherapy. It has been established that a course of balanced nutrition according to the method of alfitherapy has antibacterial, antiviral and antimetastatic effects, making it possible in some cases to dispense with operations or surgical intervention. In the process of completing a course of balanced nutrition in a period from several days to three months, many types of damaged tissues and organs are regenerated, blood vessels are restored and the blood supply to the brain is enhanced, the liver and other organs are cleared of toxins, isotopes (radiation) and heavy metals at the intracellular and intercellular levels. It is possible to restore the cognitive, speech and motor functions lost as a result of strokes due to the complete regeneration of the damaged vessels of the brain.

Preserving Integrity in the Face of Performance Threat

2012 ◽  
Vol 23 (12) ◽  
pp. 1455-1460 ◽  
Author(s):  
Lisa Legault ◽  
Timour Al-Khindi ◽  
Michael Inzlicht
Keyword(s):  
Error Detection ◽  
Error Monitoring ◽  
Error Related Negativity ◽  
Threatening Information ◽  
Electrophysiological Responses ◽  
The Face ◽  
And Performance ◽  
The Impact ◽  
The Brain

Self-affirmation produces large effects: Even a simple reminder of one’s core values reduces defensiveness against threatening information. But how, exactly, does self-affirmation work? We explored this question by examining the impact of self-affirmation on neurophysiological responses to threatening events. We hypothesized that because self-affirmation increases openness to threat and enhances approachability of unfavorable feedback, it should augment attention and emotional receptivity to performance errors. We further hypothesized that this augmentation could be assessed directly, at the level of the brain. We measured self-affirmed and nonaffirmed participants’ electrophysiological responses to making errors on a task. As we anticipated, self-affirmation elicited greater error responsiveness than did nonaffirmation, as indexed by the error-related negativity, a neural signal of error monitoring. Self-affirmed participants also performed better on the task than did nonaffirmed participants. We offer novel brain evidence that self-affirmation increases openness to threat and discuss the role of error detection in the link between self-affirmation and performance.

scholarly journals Research participants as collaborators: Background, experience and policies from the PREVENT Dementia and EPAD programmes

Dementia ◽  
2018 ◽  
Vol 17 (8) ◽  
pp. 1045-1054 ◽  
Author(s):  
Sarah Gregory ◽  
Katie Wells ◽  
Kate Forsyth ◽  
Cate Latto ◽  
Helen Szyra ◽  
...  
Keyword(s):  
Patient Involvement ◽  
Research Participant ◽  
Steering Committee ◽  
Research Participants ◽  
Prospective Cohort Studies ◽  
Participant Experience ◽  
The Impact ◽  
The Brain ◽  
Public And Patient Involvement

Aim Despite the growing importance of public and patient involvement in biomedical research, comparatively little attention has been paid to the important role of research participants themselves. Our aim in this paper is to explore the impact research participant involvement has within the PREVENT and the European Prevention of Alzheimer’s Dementia (EPAD) projects. Method In this paper, we report the experiences of involving research participants as collaborators in prospective cohort studies exploring early changes in the brain as pathways towards and risks for dementia. We use minutes and feedback from members of the panel and steering committee to understand the experience and impact on the study. Results We describe the aims and structure of the participant panel established within the PREVENT Dementia study and highlight its contributions to the organisation, conduct and future of the study. Key areas of contribution identified include recruitment, inclusion of additional sub-studies, understanding the participant experience and contributing to the future of the study. Discussion We then describe how the PREVENT Dementia panel forms the basis for participant involvement within EPAD project.

scholarly journals Is There a Link between Oropharyngeal Microbiome and Schizophrenia? A Narrative Review

2022 ◽  
Vol 23 (2) ◽  
pp. 846
Author(s):  
Stanislas Martin ◽  
Audrey Foulon ◽  
Wissam El Hage ◽  
Diane Dufour-Rainfray ◽  
Frédéric Denis
Keyword(s):  
Periodontal Disease ◽  
Research Team ◽  
Oral Microbiome ◽  
Oral Microbiota ◽  
Future Studies ◽  
The Subject ◽  
The Moment ◽  
The Impact ◽  
The Brain

The study aimed to examine the impact of the oropharyngeal microbiome in the pathophysiology of schizophrenia and to clarify whether there might be a bidirectional link between the oral microbiota and the brain in a context of dysbiosis-related neuroinflammation. We selected nine articles including three systemic reviews with several articles from the same research team. Different themes emerged, which we grouped into 5 distinct parts concerning the oropharyngeal phageome, the oropharyngeal microbiome, the salivary microbiome and periodontal disease potentially associated with schizophrenia, and the impact of drugs on the microbiome and schizophrenia. We pointed out the presence of phageoma in patients suffering from schizophrenia and that periodontal disease reinforces the role of inflammation in the pathophysiology of schizophrenia. Moreover, saliva could be an interesting substrate to characterize the different stages of schizophrenia. However, the few studies we have on the subject are limited in scope, and some of them are the work of a single team. At this stage of knowledge, it is difficult to conclude on the existence of a bidirectional link between the brain and the oral microbiome. Future studies on the subject will clarify these questions that for the moment remain unresolved.

scholarly journals A selective effect of dopamine on information-seeking

eLife ◽  
2020 ◽  
Vol 9 ◽  
Author(s):  
Valentina Vellani ◽  
Lianne P de Vries ◽  
Anne Gaule ◽  
Tali Sharot
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Information Seeking ◽  
Selective Effect ◽  
Reward Seeking ◽  
The Impact ◽  
The Brain ◽  
Insight Into ◽  
Primary Reward

Humans are motivated to seek information from their environment. How the brain motivates this behavior is unknown. One speculation is that the brain employs neuromodulatory systems implicated in primary reward-seeking, in particular dopamine, to instruct information-seeking. However, there has been no causal test for the role of dopamine in information-seeking. Here, we show that administration of a drug that enhances dopamine function (dihydroxy-L-phenylalanine; L-DOPA) reduces the impact of valence on information-seeking. Specifically, while participants under Placebo sought more information about potential gains than losses, under L-DOPA this difference was not observed. The results provide new insight into the neurobiology of information-seeking and generates the prediction that abnormal dopaminergic function (such as in Parkinson’s disease) will result in valence-dependent changes to information-seeking.

Immune cells of the epithelial ovarian cancer microenvironment

2021 ◽  
pp. 67-78
Author(s):  
Varvara Nikolaevna Zhurman ◽  
Natalia Gennadevna Plekhova ◽  
Ekaterina Valeryevna Eliseeva
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Immune Cells ◽  
Ovarian Tumor ◽  
Biologically Active ◽  
Cancer Microenvironment ◽  
Review Of The Literature ◽  
Prognostic Role ◽  
Active Substances

The article is a review of the literature, which analyzes the data on the role of cells of the immune system, cytokines and other biologically active substances secreted by them in the interstitial space of an ovarian tumor. The emphasis is made on the mechanism of realization by immune cells of the stimulating and suppressing action on the development of the tumor. Considerable attention is paid to the prognostic role of immune cells in the development of epithelial ovarian cancer.

The Impact of Ozone Treatment on Changes in Biologically Active Substances of Cardamom Seeds

2014 ◽  
Vol 79 (9) ◽  
pp. C1649-C1655 ◽  
Author(s):  
Agnieszka Joanna Brodowska ◽  
Krzysztof Śmigielski ◽  
Agnieszka Nowak ◽  
Katarzyna Brodowska ◽  
Rik Catthoor ◽  
...  
Keyword(s):  
Biologically Active Substances ◽  
Biologically Active ◽  
Ozone Treatment ◽  
The Impact ◽  
Active Substances

scholarly journals Ischemic Tolerance in Pre-Myelinated White Matter: The Role of Astrocyte Glycogen in Brain Pathology

2015 ◽  
Vol 35 (6) ◽  
pp. 951-958 ◽  
Author(s):  
Robert Fern
Keyword(s):  
White Matter ◽  
Neural Development ◽  
Energy Supply ◽  
Necessary Conditions ◽  
Volume Fraction ◽  
Glycogen Metabolism ◽  
Ischemic Tolerance ◽  
Mitochondrial Volume ◽  
Glycogen Particles

In isolated white matter, ischemic tolerance changes dramatically in the period immediately before the onset of myelination. In the absence of an extrinsic energy source, postnatal day 0 to 2 (P0 to P2) white matter axons are here shown to maintain excitability for over twice as long as axons > P2, a differential that was dependent on glycogen metabolism. Prolonged withdrawal of extrinsic energy supply tended to spare axons in zones around astrocytes, which are shown to be the sole repository for glycogen particles in developing white matter. Analysis of mitochondrial volume fraction revealed that neither axons nor astrocytes had a low metabolic rate in neonatal white matter, while oligodendroglia at older ages had an elevated metabolism. The astrocyte population is established early in neural development, and exhibits reduced cell density as maturation progresses and white matter expands. The findings show that this event establishes the necessary conditions for ischemia sensitivity in white matter and indicates that astrocyte proximity may be significant for the survival of neuronal elements in conditions associated with compromised energy supply.

scholarly journals How Pro-Environmental Legal Regulations Affect the Design Process and Management of Multi-Family Residential Buildings in Poland

Energies ◽  
2020 ◽  
Vol 13 (20) ◽  
pp. 5449
Author(s):  
Miłosz Raczyński ◽  
Radosław Rutkowski
Keyword(s):  
Design Process ◽  
Energy Supply ◽  
Residential Buildings ◽  
Design Phase ◽  
Legal Regulations ◽  
Extensive Experience ◽  
Number Of Factors ◽  
The Impact

This article addresses issues related to the quality of design and subsequent management of multi-family residential buildings in the context of their energy supply. The framework of the analysis carried out here are pro-environmental legal regulations currently in force in Poland. This article describes the impact of these regulations on the design process and the role of the designer. The requirements have been defined and the constraints have been identified. A number of factors directly related to the nature and parameters of the designed buildings and their location have been taken into consideration. On the basis of this study, the impact of legal regulations both on the method of energy supply in the buildings and on their later use and management have been presented. Positive and negative aspects of the analyzed regulations have been indicated and directions for their evaluation and optimization have been proposed. The research was carried out using real buildings, both completed and in the design phase. This article is based on the authors’ extensive experience in designing multi-family residential buildings in Poland.

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