Using Decision-Making Block of Computer-Based Intelligent Biomedical Avatar for Applied Research in Bioinformatics

2019 ◽  
Vol 9 (2) ◽  
pp. 24-34
Author(s):  
Leyla Ayvarovna Gamidullaeva ◽  
Vsevolod Chernyshenko

A biomedical task in which the definitions and properties of applied research indicators under study in bioinformatics is formalized. A wide range of traditional approaches used for predicting medical time series were reviewed. Advanced algorithms for predicting moments of reversals of biomedical trends based on machine learning tools were investigated as well. The effectiveness of different kinds of approaches was discussed, and related examples are given. An original securities price dynamics trend classification algorithm, based on the use of the sliding window methodology and biomedical avatar, is described. A general scheme of the classification algorithm to identify biomedical market phases is analyzed and results of computer modelling are presented. Selection of initial and resulting metrics is grounded.

Author(s):  
Vsevolod Chernyshenko ◽  
Vladimir Soloviev ◽  
Vadim Feklin ◽  
Mikhail Koroteev ◽  
Nikita Titov

The chapter formalizes the financial task for the definitions and properties of financial indicators under study. A wide range of traditional approaches used for predicting economic time series were reviewed. Investigated as well were the advanced algorithms for predicting moments of reversals of market trends based on machine learning tools. The chapter discusses the effectiveness of different kinds of approaches, which is illustrated with related examples. Described is an original securities price dynamics trend classification algorithm, based on the use of the sliding window methodology and financial agents. General scheme of the classification algorithm to identify market phases is analyzed and results of computer modeling are presented. Selection of initial and resulting metrics is grounded.


2019 ◽  
Author(s):  
Taufiq Anshori

AbstractThis study aimed to analyze the design of ICT-based Arabic learning model. This study was designed to find the best model of ICT-based Arabic learning. This study proposed that the integration of various fields of studies with ICT, including Arabic language learning, is undeniably vital to be enhanced in this digital era. However, the constraints experienced by some institutions, especially the educators, have not had a clear format of the use of ICT in the integration effort of the both disciplines. This study applied research and development model with a qualitative research method. This research was conducted through three phases, i.e. introduction, development and implementation. The research sampling technique was purposive sampling. The data were collected by conducting observation, interview and documentation. The data were analyzed using the techniques developed by Miles and Huberman. The results showed that the design of ICT-based Arabic learning model can be developed at MTs Negeri KEDIRI was the al-Hâsûb al-Ittishâlî model, i.e. a communicative computer-based Arabic learning model. In this model, the materials and other learning tools are designed using a computer program. Through this kind of learning models, a teacher served as learning motivator and mediator elaborating the materials that need clarification for the learners.


2016 ◽  
Vol 3 (2) ◽  
pp. 102
Author(s):  
Ahyuna Ahyuna ◽  
Irmawati Irmawati

IQ merupakan pengelompokan kecerdasan manusia, untuk mengetahui kecerdasan seseorang berbagai macam alat ukur yang digunakan diantaranya adalah tes inteligensi, tes emosional, tes spiritual, psikotes dan alat ukur lainnya. Semakin tinggi semangat orang untuk meraih sukses, semakin tinggi pula kebutuhan akan modal intelektual, emosional, psikologis, minat dan bakat. Segala kemampuan tersebut bisa jadi merupakan bakat terpendam dalam diri yang belum tergali, ataupun bakat yang harus dimunculkan dengan berbagai latihan. Tes IQ dalam penentuan dan pertimbangan pemilihan jurusan pada sekolah biasanya dilakukan secara manual dan membutuhkan waktu yang cukup banyak untuk mengetahui hasil IQ dalam penentuan pemilihan jurusan, selain itu banyak peserta tes sulit memahami untuk menghitung hasil tes IQ karena cukup rumit sehingga untuk mempermudah pihak sekolah dalam melaksanakan tes IQ penentuan jurusan maka diperlukan adanya suatu aplikasi yang berbasis komputer dan untuk membangun aplikasi yang akan digunakan bahasa pemrograman serta metode pengujian white box. Hasil evaluasi terhadap aplikasi yang dibangun sangat membantu serta mempercepat pihak sekolah dalam penentuan jurusan dan tepat dalam penentuan jurusan siswa yang disesuaikan kemampuan mereka serta membudayakan pemakaian komputer di kalangan siswa.IQ is a grouping of human intelligence, to determine a person's intellect wide range of measuring instruments used include intelligence tests, tests of emotional, spiritual tests, psychological and other measuring devices. The higher the spirit of people to achieve success, the higher the need for intellectual capital, emotional, psychological, interests and talents. All these capabilities can be a hidden talent within untapped, or talent that should be raised with the various exercises. IQ tests in the determination and consideration of election department at school is usually done manually and requires considerable time to know the results of IQ in determining the selection of majors, besides many test-takers is difficult to understand to calculate the results of an IQ test because it is quite complicated so as to facilitate the school in IQ tests determining the department implement the necessary existence of a computer-based applications and to build applications that will use the programming language as well as white-box testing methods. Results of evaluation of the applications that are built very helpful as well as accelerate the schools in the determination of the exact majors and students majoring in determining adjusted their abilities and cultivate the use of computers among students.


Author(s):  
Alphonse Chapanis

Three fallacies about generalization are that so-called basic research is more generalizable than applied research, that general findings are immediately useful for design purposes, and that the use of taxonomies increases the generalizability of human factors studies. Some factors that limit generalizability are the use of unrepresentative subjects, insufficient training subjects receive before measurements are begun, inadequate sampling of tasks and situations, inappropriate selection of dependent variables, long-term changes in the world of work, and artifacts attributable to the measurement process itself In designing a study to predict behavior in a specific application, the guiding principle is similarity. The study should be as similar as possible to the real situation. Two principles should be followed to design studies whose findings can be extrapolated to a wide range of situations: (1) design heterogeneity into the studies and (2) replicate earlier studies with variations in subjects, variables, or procedures.


Author(s):  
N. I. Pak ◽  
E. V. Asaulenko

The relevance of the study under consideration is due to the need to increase the efficiency of students independent work in solving computational problems. A theoretical rationale is proposed and the practical implementation of an automated training and diagnostic system for the formation of skills to solve problems according to the “white box” model is described. The leading idea of the study is the construction of mental schemes for a given topic, which allow to visualize the dynamics of changes in the learner’s level of ability to solve computational problems. The methods of accounting for forgetting educational information and methods of personalized selection of tasks are substantiated. The site for self-management of user independent work is available at the link: http://msbx.ru. The materials of the article are of practical value for teachers who use e-learning tools in the educational process.


2020 ◽  
Vol 7 (2) ◽  
pp. 34-41
Author(s):  
VLADIMIR NIKONOV ◽  
◽  
ANTON ZOBOV ◽  

The construction and selection of a suitable bijective function, that is, substitution, is now becoming an important applied task, particularly for building block encryption systems. Many articles have suggested using different approaches to determining the quality of substitution, but most of them are highly computationally complex. The solution of this problem will significantly expand the range of methods for constructing and analyzing scheme in information protection systems. The purpose of research is to find easily measurable characteristics of substitutions, allowing to evaluate their quality, and also measures of the proximity of a particular substitutions to a random one, or its distance from it. For this purpose, several characteristics were proposed in this work: difference and polynomial, and their mathematical expectation was found, as well as variance for the difference characteristic. This allows us to make a conclusion about its quality by comparing the result of calculating the characteristic for a particular substitution with the calculated mathematical expectation. From a computational point of view, the thesises of the article are of exceptional interest due to the simplicity of the algorithm for quantifying the quality of bijective function substitutions. By its nature, the operation of calculating the difference characteristic carries out a simple summation of integer terms in a fixed and small range. Such an operation, both in the modern and in the prospective element base, is embedded in the logic of a wide range of functional elements, especially when implementing computational actions in the optical range, or on other carriers related to the field of nanotechnology.


2017 ◽  
Vol 68 (4) ◽  
pp. 745-747 ◽  
Author(s):  
Marius Mioc ◽  
Sorin Avram ◽  
Vasile Bercean ◽  
Mihaela Balan Porcarasu ◽  
Codruta Soica ◽  
...  

Angiogenesis plays an important function in tumor proliferation, one of the main angiogenic promoters being the vascular endothelial growth factor (VEGF) which activates specific receptors, particularly VEGFR-2. Thus, VEGFR-2 has become an essential therapeutic target in the development of new antitumor drugs. 1,2,4-triazoles show a wide range of biological activities, including antitumor effect, which was documented by numerous reports. In the current study the selection of 5-mercapto-1,2,4-triazole structure (1H-3-styryl-5-benzylidenehydrazino-carbonyl-methylsulfanil-1,2,4-triazole, Tz3a.7) was conducted based on molecular docking that emphasized it as suitable ligand for VEGFR-2 and EGFR1 receptors. Compound Tz3a.7 was synthesized and physicochemically and biologically evaluated thus revealing a moderate antiproliferative activity against breast cancer cell line MDA-MB-231.


1996 ◽  
Vol 118 (3) ◽  
pp. 439-443 ◽  
Author(s):  
Chuen-Huei Liou ◽  
Hsiang Hsi Lin ◽  
F. B. Oswald ◽  
D. P. Townsend

This paper presents a computer simulation showing how the gear contact ratio affects the dynamic load on a spur gear transmission. The contact ratio can be affected by the tooth addendum, the pressure angle, the tooth size (diametral pitch), and the center distance. The analysis presented in this paper was performed by using the NASA gear dynamics code DANST. In the analysis, the contact ratio was varied over the range 1.20 to 2.40 by changing the length of the tooth addendum. In order to simplify the analysis, other parameters related to contact ratio were held constant. The contact ratio was found to have a significant influence on gear dynamics. Over a wide range of operating speeds, a contact ratio close to 2.0 minimized dynamic load. For low-contact-ratio gears (contact ratio less than two), increasing the contact ratio reduced gear dynamic load. For high-contact-ratio gears (contact ratio equal to or greater than 2.0), the selection of contact ratio should take into consideration the intended operating speeds. In general, high-contact-ratio gears minimized dynamic load better than low-contact-ratio gears.


1998 ◽  
Vol 162 ◽  
pp. 100-105
Author(s):  
Andrew J. Norton ◽  
Mark H. Jones

The Open University is the UK's foremost distance teaching university. For over twenty five years we have been presenting courses to students spanning a wide range of degree level and vocational subjects. Since we have no pre-requisites for entry, a major component of our course profile is a selection of foundation courses comprising one each in the Arts, Social Science, Mathematics, Technology and Science faculties. The Science Faculty's foundation course is currently undergoing a substantial revision. The new course, entitled “S103: Discovering Science”, will be presented to students for the first time in 1998.


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