Solid-State Nanopores for Nanoparticle Sensing

2014 ◽  
Vol 618 ◽  
pp. 8-13
Author(s):  
Lei Wang ◽  
Wen Yuan Zhao ◽  
Dan Mo ◽  
Quan Jun Liu
Keyword(s):  
Solid State ◽  
Electric Field ◽  
Comsol Multiphysics ◽  
Particle Detection ◽  
Fundamental Study ◽  
Detection Techniques ◽  
Sensing Technology ◽  
The Subject ◽  
Single Particle Detection ◽  
Low Charge

In recent years, single particle detection techniques based on driving nanoparticles through nanoscopic pores with a voltage or pressure had been the subject of numerous studies. Since particles with high charge, such as DNA and proteins, have been widely used for research, there was little information about the translocation behavior of nanosized particles which with low charge. However, nanoparticles include virus and colloids are important samples for nanopore sensing technology. In this study, we employed the solid-state nanopore to sense nanoparticles as fundamental study. Nanopore with diameter of 185 nm has been used to detect the nanoparticles with compared low zeta potential of-16 mv in different voltages. And simulations of electric field strength was made by using COMSOL Multiphysics to assist analyze the translocation behavior. The result suggests that the nanoparticles could transport the nanopore under the large electric field. By rising up the bias voltage could favor the detection of the nanoparticles.

scholarly journals Electric field interference and bimodal particle translocation in nano-integrated multipores

Nanoscale ◽  
2019 ◽  
Vol 11 (16) ◽  
pp. 7547-7553 ◽  
Author(s):  
Makusu Tsutsui ◽  
Kazumichi Yokota ◽  
Tomoko Nakada ◽  
Akihide Arima ◽  
Wataru Tonomura ◽  
...  
Keyword(s):  
Solid State ◽  
Electric Field ◽  
High Throughput ◽  
Multiple Channels ◽  
Particle Detection ◽  
Resistive Pulse ◽  
Pulse Analysis ◽  
And Control ◽  
Parallel Integration

Parallel integration of multiple channels is a fundamental strategy for high-throughput particle detection in solid-state nanopores wherein understanding and control of crosstalk is an important issue for the post resistive pulse analysis.

scholarly journals Optically Active, Self-Assembled Solid-State Nanopores for Single Particle Detection

2018 ◽  
Vol 114 (3) ◽  
pp. 492a
Author(s):  
Andreas Schlegel ◽  
Paul V. Gwozdz ◽  
Christian Heyn ◽  
August Dorn ◽  
André Drews ◽  
...  
Keyword(s):  
Solid State ◽  
Single Particle ◽  
Optically Active ◽  
Particle Detection ◽  
Self Assembled ◽  
Single Particle Detection

Electric-Field Effects on Reactions Between Oxides

1997 ◽  
Vol 481 ◽  
Author(s):  
Matthew T. Johnson ◽  
Shelley R. Gilliss ◽  
C. Barry Carter
Keyword(s):  
Solid State ◽  
Electric Field ◽  
Elevated Temperatures ◽  
Ionic Current ◽  
Reaction Rates ◽  
Solid State Reactions ◽  
Interfacial Stability ◽  
Electric Field Effects ◽  
Thin Film Diffusion ◽  
Microscopy Techniques

ABSTRACTThin films of In2O3 and Fe2O3 have been deposited on (001) MgO using pulsed-laser deposition (PLD). These thin-film diffusion couples were then reacted in an applied electric field at elevated temperatures. In this type of solid-state reaction, both the reaction rate and the interfacial stability are affected by the transport properties of the reacting ions. The electric field provides a very large external driving force that influences the diffusion of the cations in the constitutive layers. This induced ionic current causes changes in the reaction rates, interfacial stability and distribution of the phases. Through the use of electron microscopy techniques the reaction kinetics and interface morphology have been investigated in these spinel-forming systems, to gain a better understanding of the influence of an electric field on solid-state reactions.

scholarly journals Numerical and experimental investigation of alumina-based nanofluid effects on double-pipe heat exchanger thermal performances

2021 ◽  
Vol 3 (2) ◽  
Author(s):  
A. Bendaraa ◽  
My. M. Charafi ◽  
A. Hasnaoui
Keyword(s):  
Heat Exchanger ◽  
Volume Fraction ◽  
Convective Heat Transfer Coefficient ◽  
Deionized Water ◽  
Comsol Multiphysics ◽  
Exchange Coefficient ◽  
The Subject ◽  
Double Pipe ◽  
Pipe Heat ◽  
Thermoelectric Power Plant

AbstractIn this study, we investigate the thermal behaviour of nanofluids in a double-pipe heat exchanger. It is about a counterflow configuration, designed to cool a lubrication unit of a thermoelectric power plant. The subject of this work is to evaluate the thermal performances of the exchanger by using a nanofluid based on alumina suspension comparing with deionized water. In order to evaluate the thermal performance of the studied configuration, we carried out numerical experiments in an application developed on COMSOL Multiphysics environment, these experiments are utilized to show the feasibility of this application. As result, we found that the nanofluid with an increase in its volume fraction leads to an increase in the overall exchange coefficient, the convective heat transfer coefficient, as well as the efficiency and the power of the exchanger. It is noted that an increase of 1% in volume fraction, can enhance the overall exchange coefficient, the power and the effectiveness of the exchanger by 17.62%, 1.473% and 10.80% respectively. Besides, it is noted that the increase in the concentration of nanofluids leads to a narrowing of the pinch points of the inlet and outlet temperatures, which means that nanofluids are more efficient in cooling temperatures than conventional fluids.

Electric field structure optimization in IC solid state spatial light modulator

1992 ◽  
Author(s):  
Nickolay B. Kuleshov ◽  
Victor A. Tarasov ◽  
Igor V. Tokarev ◽  
Sergey S. Sarkisov
Keyword(s):  
Solid State ◽  
Electric Field ◽  
Spatial Light Modulator ◽  
Structure Optimization ◽  
Field Structure ◽  
Light Modulator

scholarly journals Production of ceramics from coal fly ash

2012 ◽  
Vol 18 (2) ◽  
pp. 245-254 ◽  
Author(s):  
Biljana Angjusheva ◽  
Emilija Fidancevska ◽  
Vojo Jovanov
Keyword(s):  
Compressive Strength ◽  
Fly Ash ◽  
Solid State ◽  
Liquid Phase ◽  
Bending Strength ◽  
Coal Fly Ash ◽  
Liquid Phase Sintering ◽  
Heating Rates ◽  
Republic Of Macedonia ◽  
The Subject

Dense ceramics are produced from fly ash from REK Bitola, Republic of Macedonia. Four types of fly ash from electro filters and one from the collected zone with particles < 0.063 mm were the subject of this research. Consolidation was achieved by pressing (P= 133 MPa) and sintering (950, 1000, 1050 and 11000C and heating rates of 3 and 100/min). Densification was realized by liquid phase sintering and solid state reaction where diopside [Ca(Mg,Al)(Si,Al)2O6] was formed. Ceramics with optimal properties (porosity 2.96?0.5%, bending strength - 47.01?2 MPa, compressive strength - 170 ?5 MPa) was produced at 1100?C using the heating rate of 10?C/min.

Fundamental Study of Cannabidiol Effect on MCF-7 with Low Voltage Pulse Electric Field

2021 ◽  
Author(s):  
Nur Adilah Abd Rahman ◽  
Muhammad Mahadi Abdul Jamil ◽  
Mohamad Nazib Adon ◽  
Ahmad Basri Zainal ◽  
Farideh Javid ◽  
...  
Keyword(s):  
Electric Field ◽  
Voltage Pulse ◽  
Low Voltage ◽  
Pulse Electric Field ◽  
Fundamental Study ◽  
Pulse Electric ◽  
Mcf 7

scholarly journals Electric field effect on magnetism in a MgO/Pd/Co system with a solid-state capacitor structure

AIP Advances ◽  
2018 ◽  
Vol 8 (11) ◽  
pp. 115122 ◽  
Author(s):  
Aya Obinata ◽  
Takamasa Hirai ◽  
Yoshinori Kotani ◽  
Kentaro Toyoki ◽  
Tetsuya Nakamura ◽  
...  
Keyword(s):  
Solid State ◽  
Electric Field ◽  
Field Effect ◽  
Electric Field Effect ◽  
Capacitor Structure

scholarly journals Tunable control of antibody immobilization using electric field

2015 ◽  
Vol 112 (7) ◽  
pp. 1995-1999 ◽  
Author(s):  
Sam Emaminejad ◽  
Mehdi Javanmard ◽  
Chaitanya Gupta ◽  
Shuai Chang ◽  
Ronald W. Davis ◽  
...  
Keyword(s):  
Solid State ◽  
Electric Field ◽  
Signal To Noise Ratio ◽  
Physical Adsorption ◽  
Antibody Immobilization ◽  
Proof Of Concept ◽  
Force Microscopy ◽  
Atomic Force ◽  
Sensing Platforms ◽  
Glass Surfaces

The controlled immobilization of proteins on solid-state surfaces can play an important role in enhancing the sensitivity of both affinity-based biosensors and probe-free sensing platforms. Typical methods of controlling the orientation of probe proteins on a sensor surface involve surface chemistry-based techniques. Here, we present a method of tunably controlling the immobilization of proteins on a solid-state surface using electric field. We study the ability to orient molecules by immobilizing IgG molecules in microchannels while applying lateral fields. We use atomic force microscopy to both qualitatively and quantitatively study the orientation of antibodies on glass surfaces. We apply this ability for controlled orientation to enhance the performance of affinity-based assays. As a proof of concept, we use fluorescence detection to indirectly verify the modulation of the orientation of proteins bound to the surface. We studied the interaction of fluorescently tagged anti-IgG with surface immobilized IgG controlled by electric field. Our study demonstrates that the use of electric field can result in more than 100% enhancement in signal-to-noise ratio compared with normal physical adsorption.

Silicon Micro-Photonic Structure for Ultra-Sensitive Biosensing

2003 ◽  
Vol 797 ◽  
Author(s):  
Bradley Schmidt ◽  
Vilson Almeida ◽  
Christina Manolatou ◽  
Stefan Preble ◽  
Michal Lipson
Keyword(s):  
Nano Particles ◽  
Particle Detection ◽  
Strong Light ◽  
Extinction Cross Section ◽  
Low Concentrations ◽  
Silicon Photonic ◽  
Micron Size ◽  
Planar Silicon ◽  
Single Particle Detection ◽  
Metal Nano Particles

ABSTRACTWe demonstrate a micron-size planar silicon photonic device that is able to detect low concentrations of metal nano-particles approaching single particle detection. This sensitivity is achieved by using strong light confining structures that enhance the extinction cross-section of metal nano-particles by orders of magnitude. Structures were fabricated and measurements of the transmission spectra of the devices demonstrate the detection of 10 nm diameter gold particles resting on the device with a density of fewer than 2 particles per 104 nm2 (the area of the sensing region surface). Using such a device, in a fluidic platform, one could detect the presence of a single metal nano-particle specifically bound to various analytes, enabling ultrasensitive detection of analytes including DNA, RNA, proteins, and antigens.

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