Fiber Formation of the Biocompatible Polymer Nanofiber Membrane by Electrospinning

2012 ◽  
Vol 557-559 ◽  
pp. 1888-1892
Author(s):  
Ching Wen Lou ◽  
Chien Lin Huang ◽  
Jin Jia Hu ◽  
Chao Tsang Lu ◽  
Zong Han Wu ◽  
...  

Electrospinning has been attributed to be one of the most effective method to prepare nano-fibers, and widely applied in assorted fields. The nanofiber membranes made by electrospinning feature high porosity and surface area, and are qualified for vascular grafts, biological scaffolds, and wound dressings. Chitosan is non-toxic and biodegradable, making it a good biocompatible material; in addition, it is also proved to be anti-bacterial and help cell growth in wounds. This research produced nanofiber membrane with polyethylene oxide (PEO) by electrospinning; the influence of the three parameters —mixture ratio of solution, electric field, and distance between the capillary tip and the collecting plate, on electrospinning was then explored. According to the results of the experiment, electrospinning formed the optimum nanofibers when the volume mixing ratio of PEO/chitosan was 60:40.

2012 ◽  
Vol 184-185 ◽  
pp. 1404-1407
Author(s):  
Jia Horng Lin ◽  
Jin Jia Hu ◽  
Chao Tsang Lu ◽  
Wen Cheng Chen ◽  
Chien Lin Huang ◽  
...  

This research produced nanofiber membrane with polyethylene oxide (PEO) by electrospinning; the influence of the three parameters —mixture ratio of solution, electric field, and distance between the capillary tip and the collecting plate, on electrospinning was then explored. According to the results of the experiment, the fiber membrane with a diameter of 120 nm could be obtained when the optimum electric filed was 0.6 kV/cm and the distance between the capillary tip and the collecting board was 15 cm. Finally, the spunlace nonwoven was coated with the electrospinning solution with the optimum parameters, creating the asymmetric dressings.


2021 ◽  
Vol 8 ◽  
Author(s):  
Ling Yu ◽  
Shubin Dou ◽  
Jinghan Ma ◽  
Qiang Gong ◽  
Mogen Zhang ◽  
...  

Antimicrobial peptides (AMPs) are a new class of promising antibacterial agents. We prepared electrospinning chitosan (CS)-polyethylene oxide (PEO) nanofiber membranes containing different concentrations of an antibacterial peptide NP10. The average diameter of nanofibers increased with the total concentration of NP10. The FTIR shows that all the peaks of CS-PEO nanofiber membranes with different concentrations of NP10 were almost the same as those of pure CS-PEO nanofiber membranes, and only the peak intensity changes. Adding NP10 can improve the thermal stability of CS-PEO nanofiber membranes. In the in vitro release experiment, NP10 was released from the CS-PEO-0.5%NP10 nanofiber membrane in a burst first and then slowly and continuously. Simultaneously, the CS-PEO-NP10 nanofiber membrane had good antibacterial activity against Escherichia coli and Staphylococcus aureus and good biocompatibility. In animal wound healing experiments, CS-PEO-0.5%NP10 nanofiber membrane had advantages over gauze and CS-PEO nanofiber membrane in wound healing. These properties may provide a choice for the clinical application of AMPs and treatment of wound infections.


2019 ◽  
Vol 50 (4) ◽  
pp. 512-525
Author(s):  
Huan Liu ◽  
Baoqi Zuo

Blend films based on polyvinyl alcohol/polyethylene oxide (70/30 wt%) undoped and doped with different concentration of graphene oxide were prepared by spiral vane electrospinning. Characteristic properties of the blend films were investigated by using X-ray diffraction and scanning electron microscopy. The sound absorption performance of the compositions (nanofiber membranes and needle punched non-woven fabric) was tested by an impedance tube. The sound absorption performance of non-woven fabric has greatly improved after combining with thin nanofiber membranes. With addition of graphene oxide, the fibers were intertwined in a loop and form a network, the areal density and surface roughness of the nanofiber membrane are reduced. Composites containing polyvinyl alcohol/polyethylene oxide nanofiber membranes and composites containing polyvinyl alcohol/polyethylene oxide/graphene oxide nanofiber membranes exhibited different sound absorption properties in different frequency bands. When the fiber coefficient of variation was small, the average sound absorption coefficient of the composite material was high. However, composites containing both polyvinyl alcohol/polyethylene oxide and polyvinyl alcohol/polyethylene oxide/graphene oxide nanofiber membranes had similar sound absorption properties, and the average sound absorption coefficient was greater than that of polyvinyl alcohol/polyethylene oxide composites.


Cellulose ◽  
2020 ◽  
Vol 27 (5) ◽  
pp. 2651-2667 ◽  
Author(s):  
Che-Min Lin ◽  
Yung-Chi Chang ◽  
Li-Chang Cheng ◽  
Chao-Hsien Liu ◽  
Shin C. Chang ◽  
...  

2015 ◽  
Vol 645-646 ◽  
pp. 1201-1206 ◽  
Author(s):  
Xiao Lin Wu ◽  
Jie Lin ◽  
Jian Yan Wang ◽  
Hang Guo

In this paper composite nanofiber membranes were prepared by electrospinning technology from poly (vinylidene fluoride) (PVDF)-poly (methyl methacrylate) (PMMA)-SiO2blend solutions with different PMMA and SiO2contents. It was found that the diameter of electrospun nanofibers was greatly increased with the added PMMA content but decreased with the added SiO2content, and when both PMMA and SiO2were added the diameter of electrospun nanofibers was decreased. With a proper ratio of the PMMA and SiO2added, the electrospum nanofiber membrane could have a suitable diameter with high porosity. The XRD results revealed that electrospun nanofiber membranes contained mainly β-phase crystal structure of PVDF, and its crystalline is reduced with the added PMMA and SiO2contents due to the inhibited crystallization of the polymer by the inorganic particles and PMMA during the solidification process. These nanofiber membranes exhibited a high electrolyte uptake, around 300%. Moreover, the incorporation of PMMA and SiO2into the nanofiber membrane improved the ionic conductivity from 1.7×10−3S/cm to 2.0×10−3S/cm at room temperature. Compared with commercial film PE, their cell cycle and charge and discharge performance were also greatly improved.


2021 ◽  
pp. 004051752110149
Author(s):  
Ye Liu ◽  
Jian Xiong ◽  
Ailin Li ◽  
Rongwu Wang ◽  
Liming Wang ◽  
...  

Interfacial solar vapor generation as an emerging technique has great potential in solving water shortage and pollution problems. Electrospun nanofiber membrane with high porosity, mechanical flexibility, numerous microsized channels for fast water transport, and low thermal conductivity offers an ideal platform for solar vapor generation. In this research work, plasmonic silver nanoparticles (Ag NPs) were utilized as photothermal materials and electrospun polyacrylonitrile (PAN) nanofiber membranes as substrates to fabricate Ag nanoparticles-uniformly decorated PAN (Ag@PAN) nanofiber membranes by electroless plating method. The morphology and chemical composition of the membranes were characterized by field emission scanning electron microscopy, Fourier transform infrared spectroscopy, and X-ray diffractometry. By varying the volume ratios of glucose and silver ammonia solution, the sizes of Ag NPs as well as the light-absorption ability of corresponding nanofiber membrane were regulated. As a result, the optimal Ag@PAN nanofiber membrane demonstrated a high light-absorption efficiency of 92.8% in the range of 280–2500 nm wavelength. The evaporation rate reached 1.34 kg m−2 h−1 and 5.83 kg m−2 h−1 under 1 sun and 5 sun irradiations, respectively. The plasmonic nanofiber membrane also exhibited long-term use stability, without any degradation in solar vapor generation performance even after 10 cycle tests. This work paves the way for the design and development of plasmonic nanofiber membranes as high-performance interfacial solar vapor generators.


Polymers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 2104
Author(s):  
Sibusiso Alven ◽  
Blessing Atim Aderibigbe

The management of chronic wounds is challenging. The factors that impede wound healing include malnutrition, diseases (such as diabetes, cancer), and bacterial infection. Most of the presently utilized wound dressing materials suffer from severe limitations, including poor antibacterial and mechanical properties. Wound dressings formulated from the combination of biopolymers and synthetic polymers (i.e., poly (vinyl alcohol) or poly (ε-caprolactone) display interesting properties, including good biocompatibility, improved biodegradation, good mechanical properties and antimicrobial effects, promote tissue regeneration, etc. Formulation of these wound dressings via electrospinning technique is cost-effective, useful for uniform and continuous nanofibers with controllable pore structure, high porosity, excellent swelling capacity, good gaseous exchange, excellent cellular adhesion, and show a good capability to provide moisture and warmth environment for the accelerated wound healing process. Based on the above-mentioned outstanding properties of nanofibers and the unique properties of hybrid wound dressings prepared from poly (vinyl alcohol) and poly (ε-caprolactone), this review reports the in vitro and in vivo outcomes of the reported hybrid nanofibers.


1998 ◽  
Vol 550 ◽  
Author(s):  
V.P. Shastri ◽  
I. Martin ◽  
R. Langer

AbstractPorous polymeric media are used in several applications such as solid supports for separations and catalysis, as well as biomedical applications such as vascular grafts and wound dressings. We have developed a novel versatile process to produce polymeric cellular solids. This process which is based on a phase extraction-co-polymer precipitation is applicable to a wide range of polymer systems including water soluble polymers. It is capable of yielding polymer foams of high porosity (> 90%) and excellent mechanical characteristics in a very short time (less than 2 hours) without limitations in foam thickness. Polymer foam with such characteristics have great utility in tissue engineering applications. We have successfully explored polymer foams of biocompatible polymers produced by the presented approach for bone and cartilage engineering using bone marrow stromal cells.


Polymers ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1291
Author(s):  
Oana Maria Ionescu ◽  
Arn Mignon ◽  
Andreea Teodora Iacob ◽  
Natalia Simionescu ◽  
Luminita Georgeta Confederat ◽  
...  

Natural compounds have been used as wound-healing promoters and are also present in today’s clinical proceedings. In this research, different natural active components such as propolis, Manuka honey, insulin, L-arginine, and Calendula officinalis infusion were included into hyaluronic acid/poly(ethylene)oxide-based electrospun nanofiber membranes to design innovative wound-dressing biomaterials. Morphology and average fiber diameter were analyzed by scanning electron microscopy. Chemical composition was proved by Fourier transform infrared spectroscopy, which indicated successful incorporation of the active components. The nanofiber membranes with propolis and Calendula officinalis showed best antioxidant activity, cytocompatibility, and antimicrobial properties against pathogen strains Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa and had an average diameter of 217 ± 19 nm with smooth surface aspect. Water vapor transmission rate was in agreement with the range suitable for preventing infections or wound dehydration (~5000 g/m2 24 h). Therefore, the developed hyaluronic acid/poly(ethylene)oxide nanofibers with additional natural components showed favorable features for clinical use as wound dressings.


2018 ◽  
Vol 57 (50) ◽  
pp. 17048-17057 ◽  
Author(s):  
Yanping Huang ◽  
Nianhua Dan ◽  
Weihua Dan ◽  
Weifeng Zhao ◽  
Zhongxiang Bai ◽  
...  

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