scholarly journals Burkitt lymphoma: Trends in children below 15 years reveal priority areas for early diagnosis activities in north-west Cameroon

2019 ◽  
Vol 3 ◽  
Author(s):  
Glenn M. Afungchwi ◽  
Peter B. Hesseling ◽  
Paul Achu ◽  
Richard Bardin ◽  
Francine Kouya
Keyword(s):  
Childhood Cancer ◽  
Burkitt Lymphoma ◽  
Population Data ◽  
Population Based ◽  
Paediatric Oncology ◽  
Incidence Rates ◽  
World Health ◽  
Entire Study ◽  
North West ◽  
The North

Background: Burkitt lymphoma is one of the most common childhood cancers in Cameroon. Incidence rates of 5.9/100 000 and 2.58 per 100 000 have been reported in two studies in 2005 and 2012 amongst children below 15 years in the North-West Region.Aim: This study seeks to examine how Burkitt lymphoma incidence has varied between the various health districts of north-west Cameroon from 2003 to 2015.Setting: North-West region of Cameroon.Method: Ethics approval was obtained from the relevant university and Health Services Institutional Review Board. Population data was obtained from the regional delegation of public health. The Paediatric Oncology Networked Database registry from two hospitals and two pathology-based registries were reviewed for cases per year from the various districts. Age-standardised incidence rates were computed for all districts by year using the World Health Organizaion world standard populations.Results: A total of 317 cases were registered. Overall age-standardised incidence rate was 3.07 per 100 000. Annual incidence ranged from 0.09 in 2003 to 6.12 in 2010. The districts with the highest incidence rates for the entire study period include Nwa with 10.54; Ndop with 5.63; Benakuma with 5.48; Ako with 4.97; and Nkambe with 4.73.Conclusion: Clustering of Burkitt lymphoma is seen in the region, with the highest incidence in Nwa, Ndop, Benakuma, Ako and Nkambe. These districts should be prioritised for awareness creation campaigns. There is need for a population-based childhood cancer registry in the region, which will use both active and passive surveillance methods to record all childhood cancer cases.

scholarly journals Geospatial and seasonal variation of bronchiolitis in England: a cohort study using hospital episode statistics

Thorax ◽  
2020 ◽  
Vol 75 (3) ◽  
pp. 262-268 ◽  
Author(s):  
Kate Marie Lewis ◽  
Bianca De Stavola ◽  
Pia Hardelid
Keyword(s):  
Hospital Admissions ◽  
Warning System ◽  
Incidence Rates ◽  
Demographic Characteristics ◽  
North West ◽  
Admission Rates ◽  
The North ◽  
Public Health Messages ◽  
Low Levels ◽  
English National Health

BackgroundRates of hospital admissions for bronchiolitis vary seasonally and geographically across England; however, seasonal differences by area remain unexplored. We sought to describe spatial variation in the seasonality of hospital admissions for bronchiolitis and its association with local demographic characteristics.MethodsSingleton children born in English National Health Service hospitals between 2011 and 2016 (n=3 727 013) were followed up for 1 year. Poisson regression models with harmonic functions to model seasonal variations were used to calculate weekly incidence rates and peak timing of bronchiolitis admissions across English regions and clinical commissioning groups (CCGs). Linear regression was used to estimate the joint association of population density and deprivation with incidence and peak timing of bronchiolitis admissions at the CCG level.ResultsBronchiolitis admission rates ranged from 30.9 per 1000 infant-years (95% CI 30.4 to 31.3) in London to 68.7 per 1000 (95% CI 67.9 to 69.5) in the North West. Across CCGs, there was a 5.3-fold variation in incidence rates and the epidemic peak ranged from week 49.3 to 52.2. Admission rates were positively associated with area-level deprivation. CCGs with earlier peak epidemics had higher population densities, and both high and low levels of deprivation were associated with earlier peak timing.ConclusionsApproximately one quarter of the variation in admission rates and two-fifths of the variation in peak timing of hospital admissions for bronchiolitis were explained by local demographic characteristics. Implementation of an early warning system could help to prepare hospitals for peak activity and to time public health messages.

scholarly journals Treatment and survival of lymphoid malignancy in the north-west of England: a population-based study

1995 ◽  
Vol 72 (3) ◽  
pp. 757-765 ◽  
Author(s):  
JHAM Youngson ◽  
JM Jones ◽  
JG Chang ◽  
M Harris ◽  
SS Banergee
Keyword(s):  
Population Based ◽  
Lymphoid Malignancy ◽  
Population Based Study ◽  
North West ◽  
The North

Is Diabetes Associated with Shoulder Pain or Stiffness? Results from a Population Based Study

2009 ◽  
Vol 36 (2) ◽  
pp. 371-377 ◽  
Author(s):  
ANTONIA COLE ◽  
TIFFANY K. GILL ◽  
E. MICHAEL SHANAHAN ◽  
PATRICK PHILLIPS ◽  
ANNE W. TAYLOR ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Shoulder Pain ◽  
Population Based ◽  
Health Study ◽  
Population Based Study ◽  
Current Smoking ◽  
North West ◽  
Second Stage ◽  
The North ◽  
Hba1c Levels

Objectives.To assess the association of shoulder pain and/or stiffness and diabetes mellitus in a population based cohort.Methods.Participants were randomly recruited from the North West Adelaide Health Study, a longitudinal, population based study. In the second stage, 3128 participants were assessed for diabetes mellitus and shoulder complaints via questionnaires, the Shoulder Pain and Disability Index (SPADI), physical assessment, blood sampling for fasting plasma glucose, and HbA1c levels.Results.Overall, 682 (21.8%) participants experienced shoulder pain and/or stiffness and 221 participants (7.1%) fulfilled criteria for diabetes mellitus. Those with diabetes had a higher prevalence of shoulder pain and/or stiffness (27.9% vs 21.3%; p = 0.025), and poorer SPADI disability subscore (p = 0.01) and total SPADI score (p = 0.02). After controlling for age, sex, obesity, and current smoking, the prevalence of shoulder pain and/or stiffness did not differ significantly between those with diabetes and those without (OR 1.05, 95% CI 0.76–1.45), nor were there significant differences in the SPADI disability subscore (p = 0.39) or total SPADI score (p = 0.32) between the 2 groups. After adjustment for covariates, there was no association between higher levels of HbA1c and shoulder pain and/or stiffness (p > 0.8). Range of shoulder movement was significantly reduced in those with diabetes (p < 0.05).Conclusions.There is a higher prevalence of shoulder pain and/or stiffness in people with diabetes mellitus. The differences observed between those with diabetes and those without can largely be explained by the confounding factors of age, sex, obesity, and current smoking.

scholarly journals Population-based surveillance for bacterial meningitis in the Dominican Republic: implications for control by vaccination

2000 ◽  
Vol 125 (3) ◽  
pp. 549-554 ◽  
Author(s):  
E. GOMEZ ◽  
M. PEGUERO ◽  
J. SANCHEZ ◽  
P. L. CASTELLANOS ◽  
J. FERIS ◽  
...  
Keyword(s):  
Bacterial Meningitis ◽  
Dominican Republic ◽  
Group B Streptococcus ◽  
Case Series ◽  
Population Based ◽  
Incidence Rates ◽  
World Health ◽  
Laboratory Methods ◽  
Group B ◽  
Health Organization

Quantifying the local burden of disease is an important step towards the introduction of new vaccines, such as Haemophilus influenzae type b (Hib) conjugate vaccine. We adapted a generic protocol developed by the World Health Organization for population-based surveillance of bacterial meningitis. All hospitals that admit paediatric patients with meningitis in the National District, Dominican Republic were included in the system and standard laboratory methods were used. The system identified 111 cases of confirmed bacterial meningitis. Hib was the leading cause of bacterial meningitis, followed by group B streptococcus, S. pneumoniae, and N. meningitidis. Unlike hospital-based case series, this population-based system was able to calculate incidence rates. The incidence of Hib meningitis was 13 cases per 100 000 children < 5 years old. The data from this study were used by the Ministry of Health to support the introduction of routine Hib vaccination and will be used to monitor its effectiveness.

scholarly journals Prevalence of obesity, food choices and socio-economic status: a cross-sectional study in the north-west of Iran

2006 ◽  
Vol 9 (8) ◽  
pp. 996-1000 ◽  
Author(s):  
Saeed Dastgiri ◽  
Reza Mahdavi ◽  
Helda TuTunchi ◽  
Elnaz Faramarzi
Keyword(s):  
Dairy Products ◽  
Population Based ◽  
Cross Sectional Study ◽  
Overweight And Obesity ◽  
Sectional Study ◽  
Cross Sectional ◽  
Essential Information ◽  
North West ◽  
The North ◽  
Prevalence Of Obesity

AbstractAimTo document the epidemiological features and influencing factors of obesity in the north-west of Iran, to provide baseline information for setting up a regional population-based centre to control and prevent obesity-related disorders in the area.MethodsIn this cross-sectional study, a total of 300 subjects were selected/studied in Tabriz, one of the major cities in Iran. Data on basic characteristics, anthropometric measurements, dietary assessment and physical activity were collected. Obesity was defined as body mass index ≥ 30 kg m− 2for both women and men.ResultsTotal prevalence of obesity in the area was 22.4% (95% confidence interval (CI): 18.0–27.6). The prevalence of obesity was 24% (95% CI: 18.5–31.4) for women and 18% (95% CI: 12.5–25.6) for men. For both women and men obesity prevalence showed a positive association with age (P < 0.001), while there was a negative correlation of obesity with education and income (P < 0.001). Fruit consumption decreased the risk of obesity in both women and men (odds ratio (OR) = 0.60, 95% CI: 0.49–0.71 vs. OR = 0.62, 95% CI: 0.51–0.74, respectively). The same significant pattern was observed for the consumption of green vegetables (OR = 0.71, 95% CI: 0.57–0.63 vs. OR = 0.86, 95% CI: 0.77–0.98 for women and men, respectively), legumes (OR = 0.70, 95% CI: 0.59–0.84 vs. OR = 0.78, 95% CI: 0.66–0.91 for women and men, respectively) and dairy products (OR = 0.73, 95% CI: 0.61–0.91 vs. OR = 0.77, 95% CI: 0.63–0.93 for women and men, respectively).ConclusionsOur study showed that educational attainment, higher income and consumption of certain food groups (i.e. vegetables, fruits, legumes and dairy products) may decrease the risk of obesity. Our findings also indicate the crucial necessity of establishing a population-based centre for obesity in the area. The essential information is now achieved to propose to local health authorities to act accordingly. However, more population-based investigations on dietary choices are needed to develop effective preventive strategies to control overweight and obesity disorders in different regions.

Long-term outcomes of adult out-of-hospital cardiac arrest in Queensland, Australia (2002–2014): incidence and temporal trends

Heart ◽  
2020 ◽  
pp. heartjnl-2020-317333
Author(s):  
Katherine Pemberton ◽  
Richard C Franklin ◽  
Emma Bosley ◽  
Kerrianne Watt
Keyword(s):  
Cardiac Arrest ◽  
Temporal Trends ◽  
Population Data ◽  
Population Based ◽  
Incidence Rates ◽  
Long Term Outcomes ◽  
Australian Bureau Of Statistics ◽  
Hospital Cardiac Arrest ◽  
Over Time

ObjectiveTo describe annual incidence and temporal trends (2002–2014) in incidence of long-term outcomes of adult out-of-hospital cardiac arrest (OHCA) of presumed cardiac aetiology attended by Queensland Ambulance Service (QAS) paramedics, by age, gender, geographical remoteness and socioeconomic status (SES).MethodsThis is a retrospective cohort study. Cases were identified using the QAS OHCA Registry and were linked with entries in the Queensland Hospital Admitted Patient Data Collection and the Queensland Registrar General Death Registry. Population data were obtained from the Australian Bureau of Statistics to calculate incidence. Inclusion criteria were adult (18+ years) residents of Queensland who suffered OHCA of presumed cardiac aetiology and survived to hospital admission. Analyses were undertaken by three mutually exclusive outcomes: (1) survival to less than 30 days (Surv<30 days); (2) survival from 30 to 364 days (Surv30–364 days); and (3) survival to 365 days or more (Surv365+ days). Incidence rates were calculated for each year by gender, age, remoteness and SES. Temporal trends were analysed.ResultsOver the 13 years there were 4393 cases for analyses. The incidence of total admitted events (9.72–10.13; p<0.01), Surv30–364 days (0.18–0.42; p<0.05) and Surv365+ days (1.94–4.02; p<0.001) increased significantly over time; no trends were observed for Surv<30 days. An increase in Surv365+ days over time was observed in all remoteness categories and most SES categories.ConclusionEvidence suggests that implemented strategies to improve outcomes from OHCA have been successful and penetrated groups living in more remote locations and the lower socioeconomic groups. These populations still require focus. Ongoing reporting of long-term outcomes from OHCA should be undertaken using population-based incidence.

scholarly journals The Part Played by Meteorological Conditions on Respiratory Mortality in Liverpool

1932 ◽  
Vol 32 (1) ◽  
pp. 67-78
Author(s):  
Hilda M. Woods ◽  
C. O. Stallybrass
Keyword(s):  
Annual Report ◽  
Medical Officer ◽  
Mortality Rates ◽  
Incidence Rates ◽  
Meteorological Conditions ◽  
Ministry Of Health ◽  
Great Caution ◽  
North West ◽  
Respiratory Mortality ◽  
The North

In the annual report of the Chief Medical Officer of the Ministry of Health for 1925 (p. 22) the incidence rates of notifications of pneumonia in four-weekly periods are compared for large geographical groups in England and Wales. These rates show the divergence between the north and north-west and the remainder of the country, and also the fact that the north-west (Lancashire and Cheshire) usually compares badly with the north. During 1923 “in none of the thirteen periods was the rate for the north-west less than 15 per cent, in excess of the all-England rate and in ten it was equal to or greater than the rate for the north.” That these remarks still apply may be seen from the figures for 1930 (Table I). If one compares some of the large Lancashire towns with London the contrast is even greater (Table II). The towns giving the largest number of notifications of pneumonia are Liverpool and Manchester. These towns alone contributed 48 per cent, of the total number of notified cases of pneumonia in Lancashire during 1930. Their combined population forms about 30 per cent, of the total. Great caution is, however, required in drawing deductions from rates of notification of pneumonia, as considerable differences exist between one place and another in the extent to which the obligation to notify is complied with. Mortality rates provide a sounder basis of comparison.

Epidemiology of myelodysplastic syndromes and chronic myeloproliferative disorders in the United States, 2001-2004, using data from the NAACCR and SEER programs

Blood ◽  
2008 ◽  
Vol 112 (1) ◽  
pp. 45-52 ◽  
Author(s):  
Dana E. Rollison ◽  
Nadia Howlader ◽  
Martyn T. Smith ◽  
Sara S. Strom ◽  
William D. Merritt ◽  
...  
Keyword(s):  
United States ◽  
Myelodysplastic Syndromes ◽  
Survival Rates ◽  
Myeloproliferative Disorders ◽  
Cancer Registries ◽  
The United States ◽  
Population Based ◽  
Incidence Rates ◽  
Chronic Myeloproliferative Disorders ◽  
The North

Abstract Reporting of myelodysplastic syndromes (MDSs) and chronic myeloproliferative disorders (CMDs) to population-based cancer registries in the United States was initiated in 2001. In this first analysis of data from the North American Association of Central Cancer Registries (NAACCR), encompassing 82% of the US population, we evaluated trends in MDS and CMD incidence, estimated case numbers for the entire United States, and assessed trends in diagnostic recognition and reporting. Based on more than 40 000 observations, average annual age-adjusted incidence rates of MDS and CMD for 2001 through 2003 were 3.3 and 2.1 per 100 000, respectively. Incidence rates increased with age for both MDS and CMD (P < .05) and were highest among whites and non-Hispanics. Based on follow-up data through 2004 from the Surveillance, Epidemiology, and End Results (SEER) Program, overall relative 3-year survival rates for MDS and CMD were 45% and 80%, respectively, with males experiencing poorer survival than females. Applying the observed age-specific incidence rates to US Census population estimates, approximately 9700 patients with MDS and 6300 patients with CMD were estimated for the entire United States in 2004. MDS incidence rates significantly increased with calendar year in 2001 through 2004, and only 4% of patients were reported to registries by physicians' offices. Thus, MDS disease burden in the United States may be underestimated.

Incidence of hematologic malignancies in Europe by morphologic subtype: results of the HAEMACARE project

Blood ◽  
2010 ◽  
Vol 116 (19) ◽  
pp. 3724-3734 ◽  
Author(s):  
Milena Sant ◽  
Claudia Allemani ◽  
Carmen Tereanu ◽  
Roberta De Angelis ◽  
Riccardo Capocaccia ◽  
...  
Keyword(s):  
B Cell ◽  
Myeloproliferative Neoplasms ◽  
B Cell Lymphoma ◽  
Hematologic Malignancies ◽  
Cancer Registries ◽  
Population Based ◽  
Incidence Rates ◽  
World Health ◽  
Southern Europe ◽  
Health Organization

AbstractChanging definitions and classifications of hematologic malignancies (HMs) complicate incidence comparisons. HAEMACARE classified HMs into groupings consistent with the latest World Health Organization classification and useful for epidemiologic and public health purposes. We present crude, age-specific and age-standardized incidence rates for European HMs according to these groupings, estimated from 66 371 lymphoid malignancies (LMs) and 21 796 myeloid malignancies (MMs) registered in 2000-2002 by 44 European cancer registries, grouped into 5 regions. Age-standardized incidence rates were 24.5 (per 100 000) for LMs and 7.55 for MMs. The commonest LMs were plasma cell neoplasms (4.62), small B-cell lymphocytic lymphoma/chronic lymphatic leukemia (3.79), diffuse B-cell lymphoma (3.13), and Hodgkin lymphoma (2.41). The commonest MMs were acute myeloid leukemia (2.96), other myeloproliferative neoplasms (1.76), and myelodysplastic syndrome (1.24). Unknown morphology LMs were commonest in Northern Europe (7.53); unknown morphology MMs were commonest in Southern Europe (0.73). Overall incidence was lowest in Eastern Europe and lower in women than in men. For most LMs, incidence was highest in Southern Europe; for MMs incidence was highest in the United Kingdom and Ireland. Differences in diagnostic and registration criteria are an important cause of incidence variation; however, different distribution of HM risk factors also contributes. The quality of population-based HM data needs further improvement.

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