scholarly journals Adolescents and young adults: A study of distribution of cancer at ages 15–39 years in a tertiary care hospital from North India: Epidemiological considerations

2017 ◽  
Vol 06 (04) ◽  
pp. 180-182 ◽  
Author(s):  
Neha Kakkar ◽  
Ajay Gupta ◽  
Neeraj Kumar Sharma ◽  
Prachi Agarwal ◽  
Jaspreet Kaur
Keyword(s):  
Young Adults ◽  
Care Center ◽  
Tertiary Care ◽  
Age Groups ◽  
Distribution Patterns ◽  
Adolescents And Young Adults ◽  
North India ◽  
Care Hospital ◽  
Common Cancer ◽  
Cancer Pattern

Abstract Purpose: This study aimed to analyze cancer pattern among adolescents and young adults (AYA) in a tertiary care center in North India. Materials and Methods: A retrospective study from January 2011 to December 2014 was undertaken on AYA cancer patients (aged 15–39 years). Results: Totally 1077 cases of AYA cancers were identified for analyzing the frequency and pattern of cancer distribution. The most common cancer was head and neck (32%) followed by breast (14.2%). The distribution pattern was observed to be varying in different age groups with lymphoma, leukemia, bone tumors, and sarcomas in adolescents while carcinomas being more frequent in young adults. Conclusion: Cancer distribution patterns are distinct among AYA in terms of epidemiology and biology.

Seroprevalence of anti-SARS-CoV-2 IgG antibodies in hospitalized patients at a tertiary referral center in North India (Preprint)

2020 ◽  
Author(s):  
Dr. Animesh Ray ◽  
Dr. Komal Singh ◽  
Souvick Chattopadhyay ◽  
Farha Mehdi ◽  
Dr. Gaurav Batra ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Age Groups ◽  
Hospitalized Patients ◽  
North India ◽  
P Value ◽  
Care Hospital ◽  
Igg Antibodies ◽  
Igg Antibody ◽  
Increased Risk ◽  
Significant Difference

BACKGROUND Seroprevalence of IgG antibodies against SARS-CoV-2 is an important tool to estimate the true extent of infection in a population. However, seroprevalence studies have been scarce in South East Asia including India, which, as of now, carries the third largest burden of confirmed cases in the world. The present study aimed to estimate the seroprevalence of anti-SARS-CoV-2 IgG antibody among hospitalized patients at one of the largest government hospital in India OBJECTIVE The primary objective of this study is to estimate the seroprevalence of SARS-CoV-2 antibody among patients admitted to the Medicine ward and ICU METHODS This cross-sectional study, conducted at a tertiary care hospital in North India, recruited consecutive patients who were negative for SARS-CoV-2 by RT-PCR or CB-NAAT. Anti-SARS-CoV-2 IgG antibody levels targeting recombinant spike receptor-binding domain (RBD) protein of SARS CoV-2 were estimated in serum sample by the ELISA method RESULTS A total of 212 hospitalized patients were recruited in the study with mean age (±SD) of 41.2 (±15.4) years and 55% male population. Positive serology against SARS CoV-2 was detected in 19.8%patients(95% CI 14.7-25.8). Residency in Delhi conferred a higher frequency of seropositivity 26.5% (95% CI 19.3-34.7) as compared to that of other states 8% (95% CI 3.0-16.4) with p-value 0.001. No particular age groups or socio-economic strata showed a higher proportion of seropositivity CONCLUSIONS Around, one-fifth of hospitalized patients, who were not diagnosed with COVID-19 before, demonstrated seropositivity against SARS-CoV-2. While there was no significant difference in the different age groups and socio-economic classes; residence in Delhi was associated with increased risk (relative risk of 3.62, 95% CI 1.59-8.21)

scholarly journals Melanoma in Adolescents and Young Adults: Evaluation of the Characteristics, Treatment Strategies, and Prognostic Factors in a Monocentric Retrospective Study

2021 ◽  
Vol 11 ◽  
Author(s):  
Paolo Del Fiore ◽  
Irene Russo ◽  
Beatrice Ferrazzi ◽  
Alessandro Dal Monico ◽  
Francesco Cavallin ◽  
...  
Keyword(s):  
Young Adults ◽  
Tnm Classification ◽  
Age Groups ◽  
Treatment Strategies ◽  
Disease Free Survival ◽  
Adolescents And Young Adults ◽  
Biological Behavior ◽  
Veneto Region ◽  
Common Cancer ◽  
Caucasian Patients

The “Veneto Cancer Registry” records melanoma as the most common cancer diagnosed in males and the third common cancer in females under 50 years of age in the Veneto Region (Italy). While melanoma is rare in children, it has greater incidence in adolescents and young adults (AYA), but literature offers only few studies specifically focused on AYA melanoma. The aim of this study was to describe the characteristics, surgical treatment, and prognosis of a cohort of AYA melanoma in order to contribute to the investigation of this malignancy and provide better patient care. This retrospective cohort study included 2,752 Caucasian patients (702 AYA and 2,050 non-AYA patients) from the Veneto Region who were over 15 years of age at diagnosis, and who received diagnosis and/or treatment from our institutions between 1998 and 2014. Patients were divided in adolescents and youth (15-25 years), young adults (26-39 years) and adults (more than 39 years) for the analysis. We found statistically significant differences in gender, primary site, Breslow thickness, ulceration, pathologic TNM classification (pTNM) stage and tumor subtype among the age groups. Disease-specific survival and disease-free survival were also different among the age groups. Our findings suggest that the biological behavior of melanoma in young people is different to that in adults, but not such as to represent a distinct pathological entity. Additional and larger prospective studies should be performed to better evaluate potential biological and cancer-specific differences between AYAs and the adult melanoma population.

scholarly journals Clinicoepidemiological Profile of Childhood Poisoning in the Pediatric Unit of a Tertiary Care Hospital in North India

2019 ◽  
pp. 1-8
Author(s):  
Rahid Rasool Malla ◽  
Khalid Kawoosa ◽  
Meryem Juwhyreeyeh ◽  
Riyaz Ahmed Malik ◽  
Asif Ahmed ◽  
...  
Keyword(s):  
Parental Education ◽  
Pediatric Population ◽  
Tertiary Care ◽  
Age Groups ◽  
Gastric Lavage ◽  
North India ◽  
Care Hospital ◽  
Age Group ◽  
College Hospital ◽  
Childhood Poisoning

Background: This study was conducted to find out the pattern of poisoning cases among the pediatric population in Srinagar and its Northwestern suburbs and compare it with what occurs elsewhere in India. Thereby we aimed to provide practical knowledge in dealing with these pediatric patients. Methods: The hospital records of children between the ages of 0-19 years admitted to the pediatric emergency ward of SKIMS Medical College Hospital Srinagar with poisoning from July 2016 to June 2018 were evaluated. Results: A total of 154 cases of poisoning were admitted in the study period, of which 89(57%) were males and 69(43%) were females. In the 0-12 year age group the poisonings were mostly in boys (68.26%) and were accidental whereas in the 13-19 year age group poisonings were mostly in girls (64%) and due to suicidal attempts. Organophoshorus poisoning was the most commonly ingested poison across all age groups (44.8%) followed by rodenticides (16.23%), kerosene (13.63%) and medications (11.68%). Interventions mostly commonly done were gastric lavage, induced vomiting. Mortaliy was seen in 2 cases over 2 years (1.29%). Conclusion: Knowledge on epidemiological and clinical features of poisoning in children according to age groups, establishing safety standards for sale and storage of harmful chemicals, and parental education can help to decrease the burden of childhood poisoning.

scholarly journals A study of etiology and epidemiology of onychomycosis from a tertiary care hospital in North India

2021 ◽  
Vol 9 (2) ◽  
pp. 559
Author(s):  
Shivani Tyagi ◽  
Neha . ◽  
Ravinder Kaur ◽  
Deepti Rawat
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Age Groups ◽  
Trichophyton Mentagrophytes ◽  
North India ◽  
Care Hospital ◽  
Candida Spp ◽  
Dermatology Department ◽  
Age Related ◽  
Etiological Agents

Background: Onychomycosis is the fungal infec­tion of nail of which the incidence varies from 0.5-12% in India and around 5% worldwide.Onychomycosis is considered to be gender and age-related disease, being commoner in males and older adults in both genders. Apart from dermatophytes, other fungal agents like yeasts and non-dermatophyte moulds are increasingly being acknowledged as important etiological agents for the same. Our aim was to study the etiology of the nail infections in patients presenting to a dermatology department in a tertiary care hospital in central Delhi.Methods: This study included nail samples from patients of various age groups with suspected onychomycosis attending dermatology clinics in our hospital over a period of 2 years. For all samples, KOH wet mount microscopic examination followed by culture on Sabouraud’s dextrose agar was done. Growth of filamentous fungi and yeast obtained on SDA were identified using conventional microbiology techniques. Statistical analysis was performed using Epitools.Results: Of the total 1061 nail samples received, maximum prevalence seen in patients of age group 21 to 50 years. The positivity of onychomycosis was 57.02%. Out of culture positive samples, 24.62% grew dermatophytes and 75.37% grew non-dermatophytes (31.40% yeasts and 43.97% non-dermatophyte moulds). Trichophyton mentagrophytes was the most common (59.73%) dermatophyte followed by T. rubrum (23.49%) while among non-dermatophyte moulds; Aspergillus niger (20.68%) was the most common followed by A. flavus (16.54%) and others. Common yeasts included Candida spp. (65.79%) and Trichosporon spp. (28.95%).Conclusions: Non- dermatophytes are emerging as major etiological agents of onychomycosis which may be accounted various host factors. So, it becomes important to correctly identify the causative fungi to ensure appropriate treatment.

scholarly journals Prevalence of voice disorders in tertiary care hospital

2021 ◽  
Vol 7 (3) ◽  
pp. 143
Author(s):  
Susmita Shrestha ◽  
Bijaya Kharel ◽  
Yogendra Amatya ◽  
Anil K. Adhikary ◽  
Yogesh Neupane
Keyword(s):  
Care Center ◽  
Tertiary Care ◽  
Age Groups ◽  
Voice Disorders ◽  
University Teaching ◽  
Voice Disorder ◽  
Care Hospital ◽  
Professional Voice Users ◽  
And Gender ◽  
Professional Voice

<p class="abstract"><strong>Background:</strong> Human voice is unique due to laryngeal configuration. However, change in voice is common with age and gender. It can also be altered by vocal abuse and misuse leading to different types of voice disorders. So, the present study aims to study the prevalence of voice disorder in patients visiting the voice clinic ENT-HNS department of Tribhuvan University Teaching Hospital tertiary care center.  </p><p class="abstract"><strong>Methods:</strong> This was a retrospective study carried out among the patients visiting voice clinic in the department of ENT-HNS for a duration of one year. The patients were evaluated for voice disorder by a team of ENT doctors and Speech pathologists using perceptual and instrumental evaluation. The patients who required surgical intervention were excluded. A descriptive study was done among patients with voice disorders requiring voice therapy.  </p><p class="abstract"><strong>Results:</strong> Out of 296 patients, the most common age group was 25-50 years with more females compared to males. Structural cause for voice disorder was most common in all age groups and gender in both professional and non-professional voice users but it was more prevalent in professional voice users.</p><p class="abstract"><strong>Conclusions:</strong> Voice disorders were more frequent in females than males and also in professional voice users as they tend to use voice more daily. The structural cause for voice disorder is the major cause of voice problems in all age groups.  </p>

The spectrum of cancer in adolescents and young adults (AYAs): An observational study in a single institution from 2015-2019.

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e13629-e13629
Author(s):  
Wei Lin Goh ◽  
Jiancheng Hong ◽  
Evelyn Wong ◽  
Victoria Wong ◽  
Daniel Quah ◽  
...  
Keyword(s):  
Young Adults ◽  
Observational Study ◽  
Germ Cell ◽  
Age Groups ◽  
Hematologic Malignancies ◽  
Adolescents And Young Adults ◽  
Germ Cell Tumours ◽  
Cancer Centre ◽  
Common Cancer ◽  
Cancer Types

e13629 Background: Cancer in adolescents and young adults (AYAOs) refers to patients diagnosed with a malignancy between 16 and 39 years old. This is thought to be 5% in the Western population. The exact incidence and distribution in Asia is uncertain although the WHO estimated 650 000 AYAs to be newly diagnosed in this part of the world in 2018. There is limited data on the incidence and epidemiology on AYAs in Asia, but it is known from the western literature that the distribution of cancer types, clinico-pathological features and outcomes in this population is very different. We therefore, sought to evaluate the pattern of cancer types among the different age groups of the AYA population seen in a high-volume single Asian tertiary cancer centre. Methods: We undertook a retrospective observational study of all patients diagnosed with cancer between 16 and 39 years old who presented to the National Cancer Centre Singapore (NCCS) from 1 January 2015 to 31 December 2019. Results: A total of 2583 cases was observed during the 5-year period. The male: female ratio was 1:1.75. The majority of the patients were between of 35-39 years (y) ( n= 1128, 44.0%). The most common cancer across the different age groups in females were sarcoma (16-19 y), hematologic malignancies (20-24 y) and breast cancer (25-29 y, 30-34 y and 35-39 y). The most common cancer across the different age groups in males were hematologic malignancies (16-19 y), germ cell tumours (20-24 y), germ cell tumours, hematologic malignancies and sarcoma (25-29 y), hematologic malignancies (30-34 y) and colorectal cancers (35-39 y). The majority of the patients presented were localized disease (38.3%), while 19.4% presented with lymphatic involvement. Amongst 507 (19.6%) patients presenting with metastatic disease, 126 patients have deceased. Conclusions: This population has unique characteristics compared to their geriatric and pediatric counterparts. With an increased incidence and expected longer survivals, more efforts are needed to better understand the clinicopathological features of the AYA population. This will enable us to better survival rates and long-term treatment outcomes.

Abdominopelvic mass in adolescents and young adults: An audit in a tertiary care center

2021 ◽  
Vol 7 (2) ◽  
pp. 119
Author(s):  
Sangeeta Pankaj ◽  
Pravin Kumar ◽  
Pratibha Kumari ◽  
Satya Kumari ◽  
Jyotsna Rani ◽  
...  
Keyword(s):  
Young Adults ◽  
Care Center ◽  
Tertiary Care ◽  
Adolescents And Young Adults ◽  
Tertiary Care Center

scholarly journals Seroprevalence of anti-SARS-CoV-2 IgG antibodies in hospitalized patients at a tertiary referral center in North India

2020 ◽  
Author(s):  
Animesh Ray ◽  
Komal Singh ◽  
Souvick Chattopadhyay ◽  
Farha Mehdi ◽  
Gaurav Batra ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Age Groups ◽  
Hospitalized Patients ◽  
North India ◽  
P Value ◽  
Care Hospital ◽  
Igg Antibodies ◽  
Igg Antibody ◽  
Increased Risk ◽  
Significant Difference

Background: Seroprevalence of IgG antibodies against SARS-CoV-2 is an important tool to estimate the true extent of infection in a population. However, seroprevalence studies have been scarce in South East Asia including India, which, as of now, carries the third largest burden of confirmed cases in the world. The present study aimed to estimate the seroprevalence of the anti-SARS-CoV-2 IgG antibody among hospitalized patients at one of the largest government hospital in India. Method: This cross-sectional study, conducted at a tertiary care hospital in North India, recruited consecutive patients who were negative for SARS-CoV-2 by RT-PCR or CB-NAAT. Anti-SARS-CoV-2 IgG antibody levels targeting recombinant spike receptor-binding domain (RBD) protein of SARS CoV-2 were estimated in serum samples by the ELISA method. Results: A total of 212 hospitalized patients were recruited in the study with mean age (+/-SD) of 41.2 (+/-15.4) years and 55% male population. Positive serology against SARS CoV-2 was detected in 19.8% patients(95% CI 14.7-25.8). Residency in Delhi conferred a higher frequency of seropositivity 26.5% (95% CI 19.3-34.7) as compared to that of other states 8% (95% CI 3.0-16.4) with p-value 0.001. No particular age groups or socio-economic strata showed a higher proportion of seropositivity. Conclusion: Around, one-fifth of hospitalized patients, who were not diagnosed with COVID-19 before, demonstrated seropositivity against SARS-CoV-2. While there was no significant difference in the different age groups and socio-economic classes; residence in Delhi was associated with increased risk (relative risk of 3.62, 95% CI 1.59-8.21) Key Words: SARS-CoV-2 IgG Antibody, Seroprevalence, Hospitalized patient, COVID-19

scholarly journals Mobile media uses and circumstances in which parents offer these devices to children: a cross sectional study in North India

2020 ◽  
Vol 7 (12) ◽  
pp. 2312
Author(s):  
Satish K. Meena ◽  
Singam Lakshmi Narsimha Reddy ◽  
Bhavna Anand ◽  
Manas P. Roy
Keyword(s):  
Tertiary Care ◽  
Age Groups ◽  
Nationwide Survey ◽  
Cross Sectional Study ◽  
North India ◽  
Care Hospital ◽  
Sectional Study ◽  
Mobile Media ◽  
Cross Sectional ◽  
Middle Income

Background: To look into circumstances in which parents offer mobile media to their children in an urban, low-middle income community from North India.Methods: Cross sectional study, enrolled 354 children from 6 months to 12 years coming for a well visit or immunization, at a tertiary care hospital from August 2016 to July 2017. A study questionnaire adopted from zero to eight common sense media nationwide survey 2013, USA used to assess the circumstances in which parents offer mobile media to their children.Results: A total of 354 children were enrolled in the study; 56.5% were male and 43.5% female. All of study population had access to handheld mobile devices (75% to smart phones, and 25% to ordinary mobile phones). The most common reason for offering mobile phone to children in all age groups was to console them while crying (73.7%). Other reasons were making them calm while travelling (42.9%), feeding the child (31.6%), and household chores (22.0%). YouTube was the most frequently used app in all age groups.Conclusions: Reasons for offering mobile media devices by parents to their children seen in this study were actually avoidable. It is the ease of parents and lack of awareness regarding optimal media uses which leads to these circumstances.

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