scholarly journals Melanoma in Adolescents and Young Adults: Evaluation of the Characteristics, Treatment Strategies, and Prognostic Factors in a Monocentric Retrospective Study

2021 ◽  
Vol 11 ◽  
Author(s):  
Paolo Del Fiore ◽  
Irene Russo ◽  
Beatrice Ferrazzi ◽  
Alessandro Dal Monico ◽  
Francesco Cavallin ◽  
...  
Keyword(s):  
Young Adults ◽  
Tnm Classification ◽  
Age Groups ◽  
Treatment Strategies ◽  
Disease Free Survival ◽  
Adolescents And Young Adults ◽  
Biological Behavior ◽  
Veneto Region ◽  
Common Cancer ◽  
Caucasian Patients

The “Veneto Cancer Registry” records melanoma as the most common cancer diagnosed in males and the third common cancer in females under 50 years of age in the Veneto Region (Italy). While melanoma is rare in children, it has greater incidence in adolescents and young adults (AYA), but literature offers only few studies specifically focused on AYA melanoma. The aim of this study was to describe the characteristics, surgical treatment, and prognosis of a cohort of AYA melanoma in order to contribute to the investigation of this malignancy and provide better patient care. This retrospective cohort study included 2,752 Caucasian patients (702 AYA and 2,050 non-AYA patients) from the Veneto Region who were over 15 years of age at diagnosis, and who received diagnosis and/or treatment from our institutions between 1998 and 2014. Patients were divided in adolescents and youth (15-25 years), young adults (26-39 years) and adults (more than 39 years) for the analysis. We found statistically significant differences in gender, primary site, Breslow thickness, ulceration, pathologic TNM classification (pTNM) stage and tumor subtype among the age groups. Disease-specific survival and disease-free survival were also different among the age groups. Our findings suggest that the biological behavior of melanoma in young people is different to that in adults, but not such as to represent a distinct pathological entity. Additional and larger prospective studies should be performed to better evaluate potential biological and cancer-specific differences between AYAs and the adult melanoma population.

scholarly journals Adolescents and young adults: A study of distribution of cancer at ages 15–39 years in a tertiary care hospital from North India: Epidemiological considerations

2017 ◽  
Vol 06 (04) ◽  
pp. 180-182 ◽  
Author(s):  
Neha Kakkar ◽  
Ajay Gupta ◽  
Neeraj Kumar Sharma ◽  
Prachi Agarwal ◽  
Jaspreet Kaur
Keyword(s):  
Young Adults ◽  
Care Center ◽  
Tertiary Care ◽  
Age Groups ◽  
Distribution Patterns ◽  
Adolescents And Young Adults ◽  
North India ◽  
Care Hospital ◽  
Common Cancer ◽  
Cancer Pattern

Abstract Purpose: This study aimed to analyze cancer pattern among adolescents and young adults (AYA) in a tertiary care center in North India. Materials and Methods: A retrospective study from January 2011 to December 2014 was undertaken on AYA cancer patients (aged 15–39 years). Results: Totally 1077 cases of AYA cancers were identified for analyzing the frequency and pattern of cancer distribution. The most common cancer was head and neck (32%) followed by breast (14.2%). The distribution pattern was observed to be varying in different age groups with lymphoma, leukemia, bone tumors, and sarcomas in adolescents while carcinomas being more frequent in young adults. Conclusion: Cancer distribution patterns are distinct among AYA in terms of epidemiology and biology.

The spectrum of cancer in adolescents and young adults (AYAs): An observational study in a single institution from 2015-2019.

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e13629-e13629
Author(s):  
Wei Lin Goh ◽  
Jiancheng Hong ◽  
Evelyn Wong ◽  
Victoria Wong ◽  
Daniel Quah ◽  
...  
Keyword(s):  
Young Adults ◽  
Observational Study ◽  
Germ Cell ◽  
Age Groups ◽  
Hematologic Malignancies ◽  
Adolescents And Young Adults ◽  
Germ Cell Tumours ◽  
Cancer Centre ◽  
Common Cancer ◽  
Cancer Types

e13629 Background: Cancer in adolescents and young adults (AYAOs) refers to patients diagnosed with a malignancy between 16 and 39 years old. This is thought to be 5% in the Western population. The exact incidence and distribution in Asia is uncertain although the WHO estimated 650 000 AYAs to be newly diagnosed in this part of the world in 2018. There is limited data on the incidence and epidemiology on AYAs in Asia, but it is known from the western literature that the distribution of cancer types, clinico-pathological features and outcomes in this population is very different. We therefore, sought to evaluate the pattern of cancer types among the different age groups of the AYA population seen in a high-volume single Asian tertiary cancer centre. Methods: We undertook a retrospective observational study of all patients diagnosed with cancer between 16 and 39 years old who presented to the National Cancer Centre Singapore (NCCS) from 1 January 2015 to 31 December 2019. Results: A total of 2583 cases was observed during the 5-year period. The male: female ratio was 1:1.75. The majority of the patients were between of 35-39 years (y) ( n= 1128, 44.0%). The most common cancer across the different age groups in females were sarcoma (16-19 y), hematologic malignancies (20-24 y) and breast cancer (25-29 y, 30-34 y and 35-39 y). The most common cancer across the different age groups in males were hematologic malignancies (16-19 y), germ cell tumours (20-24 y), germ cell tumours, hematologic malignancies and sarcoma (25-29 y), hematologic malignancies (30-34 y) and colorectal cancers (35-39 y). The majority of the patients presented were localized disease (38.3%), while 19.4% presented with lymphatic involvement. Amongst 507 (19.6%) patients presenting with metastatic disease, 126 patients have deceased. Conclusions: This population has unique characteristics compared to their geriatric and pediatric counterparts. With an increased incidence and expected longer survivals, more efforts are needed to better understand the clinicopathological features of the AYA population. This will enable us to better survival rates and long-term treatment outcomes.

scholarly journals The reliability and validity of a screening scale for online gaming disorder among Chinese adolescents and young adults

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Xuechan Lyu ◽  
Tianzhen Chen ◽  
Zhe Wang ◽  
Jing Lu ◽  
Chenyi Ma ◽  
...  
Keyword(s):  
Young Adults ◽  
Age Groups ◽  
Reliability And Validity ◽  
Online Gaming ◽  
Chinese Adolescents ◽  
Model Fit ◽  
Adolescents And Young Adults ◽  
Gaming Disorder ◽  
Good Reliability ◽  
Screening Scale

Abstract Background In recent years, there have been frequent reports of gaming disorder in China, with more focus on young people. We developed and psychometrically tested a Gaming Disorder screening scale (i.e., Gaming Disorder Screening Scale - GDSS) for Chinese adolescents and young adults, based on the existing scales and diagnostic criteria, but also considering the development status of China. Methods For testing content and criterion validity, 1747 participants competed the GDSS and the Internet Addiction Test (IAT). After 15 days, 400 participants were retested with the scales for to assess test-retest reliability. Besides, 200 game players were interviewed for a diagnosis of gaming disorder. Results The Cronbach’s alpha coefficient on the GDSS was 0.93. The test-retest coefficient of 0.79. Principal components analysis identified three factors accounting for 62.4% of the variance; behavior, functioning, cognition and emotion. Confirmatory factor analysis showed a good model fit to the data (χ2 /df = 5.581; RMSEA =0.074; TLI = 0.916, CFI = 0.928). The overall model fit was significantly good in the measurement invariance tested across genders and different age groups. Based on the clinical interview, the screening cut-off point was determined to be ≥47 (sensitivity 41.4%, specificity 82.3%). Conclusions The GDSS demonstrated good reliability and validity aspects for screening online gaming disorder among Chinese adolescents and young adults.

scholarly journals Germ Cell Tumors in Adolescents and Young Adults

2019 ◽  
Vol 15 (8) ◽  
pp. 433-441 ◽  
Author(s):  
Adriana Fonseca ◽  
A. Lindsay Frazier ◽  
Furqan Shaikh
Keyword(s):  
Young Adults ◽  
Germ Cell ◽  
Age Groups ◽  
Germ Cell Tumors ◽  
Adolescents And Young Adults ◽  
Childhood Cancers ◽  
Therapeutic Approaches ◽  
Cancer Specialists ◽  
Research Initiatives ◽  
Common Malignancy

Germ cell tumors (GCTs) are rare in childhood, representing only 3.5% of childhood cancers, but a common malignancy in adolescents and young adults (AYAs), accounting for 13.9% of neoplasms in adolescents between age 15 and 19 years. The overall outcomes of patients treated for GCTs are excellent. However, as seen in other cancers, outcomes for AYA patients are significantly worse. Understanding the reasons for this observation has led to different approaches to diagnosis, staging, and treatment. The Malignant Germ Cell International Consortium was created to bring together pediatric, gynecologic, and testicular cancer specialists to promote research initiatives and provide evidence-based approaches in the management of GCTs across different age groups. Collaboration between multiple subspecialties is essential to further understand the disease continuum, the underlying biologic characteristics, and the development of appropriate therapeutic approaches. This review focuses on the unique characteristics of patients with extracranial GCTs in the AYA group.

scholarly journals Change in disparities of dietary quality score (FSAm-NPS) in adolescents and young adults between 2004 and 2014 in Belgium

2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Lucille Desbouys ◽  
Manon Rouche ◽  
Karin De Ridder ◽  
Katia Castetbon
Keyword(s):  
Young Adults ◽  
Age Groups ◽  
Food Group ◽  
Regional Disparities ◽  
Adolescents And Young Adults ◽  
Dietary Quality ◽  
Weighted Mean ◽  
Regional Characteristics ◽  
Significant Difference ◽  
Index Of Inequality

AbstractIntroductionThe transition from adolescence toward adulthood is a critical period regarding changes in dietary behaviours. Moreover at these ages, socio-economic and regional disparities in food group consumption are observed. The aim of our study was to determine how the nutritional quality of diet, measured by the modified Nutrient Profiling System of the British Food Standards Agency (FSAm-NPS), evolved between 2004 and 2014, according to socio-economic and regional characteristics of adolescents and young adults living in Belgium.Material and methodsTwo non-consecutive 24-hour dietary recalls were carried out in two nationally-representative samples of 15-to-39-year-old respondents included in the Belgian Food Consumption Surveys in 2004 (n = 1,186) and 2014 (n = 952). Weighting factor (according to age, gender, day of recall, season and province) and sample design were considered. The weighted mean individual FSAm-NPS was computed from all foods and beverages consumed and converted into a scale from 0 (less favourable diet) to 100 (more favourable diet). Slope (SII) and Relative (RII) Index of Inequality were compared between 2004 and 2014 in three age groups (15–18 y, 19–25 y and 26–39 y), adjusting for gender, energy intake, and other socio-economic and regional characteristics.ResultsIn the three age groups, the weighted mean FSAm-NPS significantly increased between 2004 and 2014 (2004: 55.2 (SEM: 0.2) vs. 2014: 57.3 (0.5), p < 0.001 in 15–18-year-olds; 54.9 (0.6) vs. 58.0 (0.4), p < 0.001 in 19–25-year-olds; 56.9 (0.3) vs 58.3 (0.3), p < 0.01 in 26–39-year-olds). While a significant FSAm-NPS gradient was observed according to household education among 15–18- and 26–39-year-olds in 2004 (adjusted SII: 2.56 (95% CI: 1.08–4.04) and 2.73 (0.34–5.12), respectively; RII: 1.05 (1.02–1.08) and 1.05 (1.01–1.09)), no significant difference was found in 2014. Conversely, no significant score disparity was observed according to household type in 2004, but disparities appeared in 2014: index of inequality were significant among subjects aged 19–25 y (SII: 3.89 (0.62–7.17); RII: 1.07 (1.01–1.13)) and 26–39 y (SII: 2.74 (0.31–5.17); RII: 1.05 (1.01–1.09)), the FSAm-NPS being more favourable for those living in two-parent families. The FSAm-NPS was generally higher for subjects living in Flanders than those in Wallonia (significant SII and RII only among 26–39-year-olds), the magnitude of regional disparities remaining stable over time.DiscussionOverall FSAm-NPS improved during this 10-year period, but differentially according to family structure and household education. However, statistical power was weakened by the limited sample size. Additional investigations of changes in food group consumption disparities will complement our interpretations.

scholarly journals A study on prevalence of hypertension and its relationship with overweight and obesity in adolescents and young adults, Nizamabad city

2019 ◽  
Vol 6 (9) ◽  
pp. 3861
Author(s):  
G. Chethan Raj ◽  
Syam Sundar Junapudi
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Young Adults ◽  
Age Groups ◽  
Overweight And Obesity ◽  
Adolescents And Young Adults ◽  
Age Group ◽  
Contributing Factors ◽  
Cross Sectional ◽  
Study Population

Background: The overall imbalance between unhealthy diet intake and physical activity leads to obesity which contributes to high blood pressure and high cholesterol. It is multi factorial disease and changes in the levels of blood pressure and blood lipids differ by age sex and race and are influenced by body fat and dietary patterns. These risk factors need to be monitored and evaluated in childhood and adolescents. So identifying and modifying the risk factors in early age reduces the incidence in adolescents and adult. Prevalence of hypertension varies across countries and states. The prevalence of hypertension in India is reported as ranging from 10 to 30.9%. The objective of the present study is to observe the prevalence hypertension among study population and to study contributing factors for hypertension among study population.Methods: A cross sectional study done on 100 adolescents and young adults of both sexes in the age group 17 to 25 years from 2 degree colleges randomly selected in Nizamabad city, Telangana, India.Results: In the present study population 52 were males and 48 were females, 22 students belongs to rural area and 78 belongs to urban area, pre-hypertension and hypertension was found 8% in both age groups. Overweight and obesity (>25) was found 7% in 17-19 age group and 9% in 20-25 age group. Pre-hypertension and hypertension was found among 10% of alcoholics.Conclusions: The result of our study concluded that there is increasing prevalence of hypertension with increase in age and is associated with overweight and obesity. 

scholarly journals A structural model of well-being, spontaneity and self-efficacy: Italian validation between adolescents and young adults

2018 ◽  
Vol 40 (2) ◽  
pp. 136-143 ◽  
Author(s):  
Lucia Ronconi ◽  
Noemi Giannerini ◽  
Ines Testoni ◽  
Maria Zulian ◽  
Maria Silvia Guglielmin
Keyword(s):  
Young Adults ◽  
Psychological Distress ◽  
Self Efficacy ◽  
Structural Model ◽  
Age Groups ◽  
Well Being ◽  
Three Dimensions ◽  
Adolescents And Young Adults ◽  
Snowball Sampling ◽  
Separation From Parents

Abstract Introduction: The passage from adolescence to young adulthood introduces many challenges and chances aimed at promoting independence, financial self-sufficiency, assumption of responsibilities and separation from parents. Literature shows that in the continuum between these two phases of life, many factors intervene, producing significant differentiations. Methods: This study considered three dimensions - well-being, measured through the Clinical Outcomes in Routine Evaluation-Outcome Measure (CORE-OM); spontaneity, measured through the Spontaneity Assessment Inventory-Revised (SAI-R); and self-efficacy, measured through the General Self-Efficacy scale (GSE). The study involved two groups of Italian participants: 495 adolescents, aged between 13 and 19 years, selected at a high school; and 368 young adults, aged between 18 and 30 years, recruited by snowball sampling. Results: Results of confirmatory factor analysis for each instrument in each group indicate the validity of the three instruments for both age groups. No significant differences were found between adolescents and young adults on total or subtotal scores of the CORE-OM, except for the risk factor. Conversely, the mean scores obtained with SAI-R and GSE were very different between adolescents and young adults. Conclusions: The results of path analysis show a significant mediation of spontaneity in the link between self-efficacy and all specific psychological distress domains for adolescents. Instead, there is a significant mediation of spontaneity between self-efficacy and all specific psychological distress domains except the risk domain for young adults.

TALES (GAWĘDA) AND STORYTELLING AS A MEANS OF CARE AND UPBRINGING IN EARLY SCHOOL

2019 ◽  
Vol 10 (2) ◽  
pp. 271-284
Author(s):  
Jakub Jerzy Czarkowski
Keyword(s):  
Young Adults ◽  
Preschool Children ◽  
Fairy Tales ◽  
Age Groups ◽  
Older Age ◽  
Adolescents And Young Adults ◽  
Cultural Education ◽  
Early School

Gawęda - the story has been an important element of cultural education since the earliest times. Children like to listen to fairy tales. It is a great way for them to learn important and impossible to show matters, e.g. values. The study presented on different groups of preschool children (six-year-olds) shows that storytelling - listening is still an attractive way to upbringing. It is also worth conducting similar studies in older age groups, including adolescents and young adults. The presented research and considerations also lead to the conclusion that to some extent we are all children and we need such stories. Storytelling serves listeners, but it can also be used by storytellers because good storytelling requires reflection and also serves the development of a tutor storyteller.

scholarly journals Osteosarcoma in Adolescents and Young Adults

Cells ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 2684
Author(s):  
Jun Ah Lee ◽  
Jiwon Lim ◽  
Hye Young Jin ◽  
Meerim Park ◽  
Hyeon Jin Park ◽  
...  
Keyword(s):  
Young Adults ◽  
Young Children ◽  
Clinical Characteristics ◽  
Local Treatment ◽  
Age Groups ◽  
The Elderly ◽  
Adolescents And Young Adults ◽  
Dependent Manner ◽  
Female Ratio ◽  
Male To Female

The epidemiology of osteosarcoma in adolescents and young adults (AYA) remains unclear. We aimed to assess and compare the clinical features of osteosarcoma between AYA and other age groups. We retrieved osteosarcoma cases diagnosed between 1999 and 2017 from the Korea Central Cancer Registry. We compared survival trends and clinical characteristics between AYA and other age groups. AYA comprised 43.3% (1309/3022) of the osteosarcoma cases. Compared to other age groups, the male-to-female ratio was highest in AYA (1.61:1). The proportion of tumors located in an extremity was 80.3% in AYA, which was lower than in young children (92.5%) or pubertal children (93.8%) but higher than in adults (55.7%) or the elderly (47.5%). As for treatments, 71.2% of AYA received local treatment and systemic chemotherapy, and 28.8% received only local treatment (surgery: 261, radiotherapy: 9, surgery and radiotherapy: 5). The 5-year overall survival (OS) was lower in AYA (68%) than in young children (78%) or pubertal children (73%) but higher than in adults (47%) or the elderly (25%). When AYA were divided into five subgroups by age, patients aged 15–19 years constituted the largest proportion (45.4%, n = 594). Additionally, the proportion of patients with a non-extremity tumor increased in an age-dependent manner, from 10.3% in AYA aged 15–19 years to 35.3% in AYA aged 35–39 years. OS did not significantly differ among the different age subgroups of AYA. The clinical characteristics and OS of the AYA were more similar to those of children than to those of adults. There is a need for cooperation between pediatric and adult oncologists for effective osteosarcoma treatment in AYA.

Sign in / Sign up

Export Citation Format

Share Document