scholarly journals Evaluating the Novel Coronavirus infection outbreak surveillance results in a state hospital: a retrospective study

2021 ◽  
Vol 21 (3) ◽  
pp. 1107-1116
Author(s):  
Ezgi Dirgar ◽  
Betül Tosun ◽  
Soner Berşe ◽  
Nuran Tosun
Keyword(s):  
Retrospective Study ◽  
Clinical Symptoms ◽  
Clinical Status ◽  
Age Groups ◽  
World Health ◽  
Health Concern ◽  
The Novel ◽  
Global Public Health ◽  
Novel Coronavirus ◽  
Health Organization

Background: Coronavirus disease (COVID-19) has raised the global public health concern and has been declared a pan- demic by the World Health Organization. Objectives: This study was aimed to examine the clinical course and outcomes of the patients with COVID-19 in the south- eastern part of Turkey. Methods: This retrospective study was conducted on the files of 173 patients who were diagnosed with COVID-19. The “COVID-19 Case Information Form” in the patients’ medical records was used. Results: Of the patients with COVID-19, 64.2% were male and 16.2% had a chronic disease. Their mean age was 34.76±25.75 years. Cough and fatigue were the most common clinical symptoms at admission with 38.7%. The patients at the age of 65 and over were treated mostly in the intensive care unit, and the symptoms associated with the cardiovascular and nausea and vomiting were observed more often (p<0.05). Conclusions: It was found that the majority of the patients were male and there were differences between the age groups in terms of transmission route, the clinic where they were being followed-up, some symptoms, and clinical status outcome. It is recommended that multi-center, prospective, experimental, or observational studies with larger samples should be and the patients should be followed-up for longer periods. Keywords: COVID-19; coronavirus; surveillance; retrospective study.

scholarly journals Cutaneous presentation of COVID-19 Case Report

2020 ◽  
Vol 3 (3) ◽  
pp. 01-02
Author(s):  
Khadiga Ismail
Keyword(s):  
Public Health Emergency ◽  
World Health ◽  
The Novel ◽  
Scientific Journals ◽  
Global Public Health ◽  
The World ◽  
Global Spread ◽  
Novel Coronavirus ◽  
Health Organization ◽  
Recent Attention

COVID-19 has high transmissibility and infectivity among human. On January 30, 2020, the World Health Organization (WHO) in an effort to slow down the global spread of the virus declared the outbreak, “A global public health emergency of international concern". The skin manifestations of the novel coronavirus COVID-19 were not recognized at the early stages of the pandemic but have received much recent attention in scientific journals. Reported manifestations range from pseudo-chilblains to a morbilliform (measles-like) exanthem, urticaria, vesicular eruptions, a dengue-like petechial rash and ovate scaling macules, and plaques mimicking pityriasis rosea.

scholarly journals SARS – COV-2 (COVID-19) Pandemic: A Critical Review on Novel Coronavirus Pathogenesis, Clinical Diagnosis and Treatment

2020 ◽  
Vol 10 (3) ◽  
pp. 241-252
Author(s):  
Ruchi Jain ◽  
Nilesh Jain ◽  
Surendra Kumar Jain ◽  
Ram C Dhakar
Keyword(s):  
World Health ◽  
The Novel ◽  
Global Public Health ◽  
Future Studies ◽  
The Public ◽  
The Third ◽  
Treatment And Prevention ◽  
Published Evidence ◽  
Novel Coronavirus ◽  
Health Organization

The 2019-nCoV is officially called SARS-CoV-2 and the disease is named COVID-19. The Novel coronavirus (SARS-CoV-2) caused pneumonia in Wuhan, China in December 2019 is a highly contagious disease. The World Health Organization (WHO) has declared it as a global public health emergency. This is the third serious Coronavirus outbreak in less than 20 years, following SARS in 2002–2003 and MERS in 2012. Currently, the research on novel coronavirus is still in the primary stage. It is currently believed that this deadly Coronavirus strain originated from wild animals at the Huanan market in Wuhan by Bats, snakes and pangolins have been cited as potential carriers. On the basis of current published evidence, we systematically summarize the epidemiology, clinical characteristics, diagnosis, treatment and prevention of COVID-19. This review in the hope of helping the public effectively recognize and deal with the novel coronavirus (SARS-CoV-2) and providing a reference for future studies. Keywords: SARS-CoV-2, COVID-19, Coronavirus, pneumonia, Respiratory infection

scholarly journals Role of nutrients regulation in the immune system in preventing COVID-19 infection: A brief review

2021 ◽  
Vol 13 (2) ◽  
pp. 760-765
Author(s):  
Anamika Chauhan
Keyword(s):  
Immune System ◽  
Age Groups ◽  
World Health ◽  
The Novel ◽  
Beneficial Effects ◽  
Coronavirus Infection ◽  
The Common ◽  
Novel Coronavirus ◽  
Health Organization

This review aimed to focus on using foods to boost immunity against COVID-19 in all age groups. In human, coronavirus causes the common cold, severe acute respiratory syndrome (SARS), and a major threat to public health. The novel coronavirus was declared a pandemic by the World Health Organization due to its rapid infectivity. COVID-19 infection is most probably reported in people with low immunity response. The nutrients, which show beneficial effects on the immune system, are called immune nutrients and diet is called immune diet. A healthy diet can reduce the risk of infection of COVID-19 and can prevent disease. Nutritional food intake is also necessary for people with chronic illness, obese persons, diabetes, cardiovascular disease, cognitive dysfunction like anxiety and depression. All nutrients are essential for maintaining immunity and providing appropriate amounts of protein, fat, carbohydrate, vitamins, and minerals for the surveillance mode of keeping us from getting sick. The use of plenty of water, minerals such as micronutrients, zinc, copper, selenium, iron, magnesium, food rich in vitamins, and a good lifestyle can promote health and overwhelm this coronavirus infection.

scholarly journals SARS-CoV-2 infection and the antiviral innate immune response

2020 ◽  
Author(s):  
Hui Yang ◽  
Yingying Lyu ◽  
Fajian Hou
Keyword(s):  
Immune Response ◽  
Innate Immune Response ◽  
Clinical Manifestations ◽  
Innate Immune ◽  
World Health ◽  
The Novel ◽  
Global Public Health ◽  
Replication Process ◽  
Novel Coronavirus ◽  
Health Organization

Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak began in December 2019, causing the illness known as the novel coronavirus disease 2019 (COVID-19). The virus spread rapidly worldwide to become a global public health emergency. As of 15 November 2020, more than 53 million confirmed cases and over one million deaths worldwide have been reported (World Health Organization, 2020). The SARS-CoV-2 genome was sequenced and studies are ongoing to further understand the epidemiology, clinical manifestations, etiological structure, cellular receptor angiotensin II converting enzyme (ACE2), and intracellular replication process of the virus. Currently, thousands of clinical trials related to SARS-CoV-2 are underway (https://clinicaltrials.gov/). However, no vaccines or drugs have yet been approved, until very recently, for direct treatment or prevention of COVID-19 and only supportive treatment has been applied clinically. This review will discuss the possible mechanism of the innate immune response to SARS-CoV-2 infection and provide insight into the development of related therapeutics.

scholarly journals SARS CoV-2. The New Pandemic: Review of Present Literature

2020 ◽  
Vol 8 (1) ◽  
pp. 4-10
Author(s):  
Sri Sandhya K
Keyword(s):  
Clinical Symptoms ◽  
Symptomatic Treatment ◽  
Control Measures ◽  
World Health ◽  
Health Concern ◽  
Effective Vaccine ◽  
Global Public Health ◽  
Corona Virus ◽  
Infectivity Rate ◽  
Health Organization

A novel Corona virus discovered during a pneumonia outbreak in Wuhan city, China has raised a global public health concern. This virus spread across the world affecting various countries and was declared a pandemic by World Health Organization(WHO). The outbreak started in December 2019 and by first week of April 2020, 212 countries were affected with more than 1million confirmed cases with a death roll of 79,235 worldwide. This disease was named as COVID-19 and the causative agent was named as Severe Acute Respiratory Syndrome Corona Virus -2 (SARS-CoV-2) due to its genetic similarity with SARS virus. SARS-CoV-2 is transmitted by respiratory droplets and by contact. Clinical symptoms include high fever, sore throat, cough, breathlessness, progress to pneumonia, acute respiratory distress and multisystem dysfunction. Infectivity rate is high with SARSCoV2 , as a result many countries are affected. Control measures like are quarantine, lockdown, regular handwashing, social distancing have been indicated by WHO and being followed by various countries. Due unavailability of an effective vaccine and specific antiviral medication against the virus, only symptomatic treatment along with the isolation of the patient is being done

scholarly journals COVID-19: The Potential Treatment of Pulmonary Fibrosis Associated with SARS-CoV-2 Infection

2020 ◽  
Vol 9 (6) ◽  
pp. 1917 ◽  
Author(s):  
Kacper Lechowicz ◽  
Sylwester Drożdżal ◽  
Filip Machaj ◽  
Jakub Rosik ◽  
Bartosz Szostak ◽  
...  
Keyword(s):  
Pulmonary Fibrosis ◽  
Age Groups ◽  
Pulmonary Involvement ◽  
World Health ◽  
The Novel ◽  
Wide Range ◽  
The World ◽  
Novel Coronavirus ◽  
Health Organization ◽  
The Right

In December 2019, a novel coronavirus, SARS-CoV-2, appeared, causing a wide range of symptoms, mainly respiratory infection. In March 2020, the World Health Organization (WHO) declared Coronavirus Disease 2019 (COVID-19) a pandemic, therefore the efforts of scientists around the world are focused on finding the right treatment and vaccine for the novel disease. COVID-19 has spread rapidly over several months, affecting patients across all age groups and geographic areas. The disease has a diverse course; patients may range from asymptomatic to those with respiratory failure, complicated by acute respiratory distress syndrome (ARDS). One possible complication of pulmonary involvement in COVID-19 is pulmonary fibrosis, which leads to chronic breathing difficulties, long-term disability and affects patients’ quality of life. There are no specific mechanisms that lead to this phenomenon in COVID-19, but some information arises from previous severe acute respiratory syndrome (SARS) or Middle East respiratory syndrome (MERS) epidemics. The aim of this narrative review is to present the possible causes and pathophysiology of pulmonary fibrosis associated with COVID-19 based on the mechanisms of the immune response, to suggest possible ways of prevention and treatment.

scholarly journals Cutaneous presentation of COVID-19 Case Report

2020 ◽  
Vol 3 (3) ◽  
pp. 01-02
Author(s):  
Khadiga Ahmed Ismail ◽  
Mahmoud Khalifa Marzouq ◽  
Ahmed Mahmoud Khalifa ◽  
Osama Mahmoud Khalifa
Keyword(s):  
Public Health Emergency ◽  
World Health ◽  
The Novel ◽  
Scientific Journals ◽  
Global Public Health ◽  
The World ◽  
Global Spread ◽  
Novel Coronavirus ◽  
Health Organization ◽  
Recent Attention

COVID-19 has high transmissibility and infectivity among human. On January 30, 2020, the World Health Organization (WHO) in an effort to slow down the global spread of the virus declared the outbreak, “A global public health emergency of international concern". The skin manifestations of the novel coronavirus COVID-19 were not recognized at the early stages of the pandemic but have received much recent attention in scientific journals. Reported manifestations range from pseudo-chilblains to a morbilliform (measles-like) exanthem, urticaria, vesicular eruptions, a dengue-like petechial rash and ovate scaling macules, and plaques mimicking pityriasis rosea.

scholarly journals Potential Immunotherapy against SARS-CoV-2: Strategy and Status

Coronaviruses ◽  
2020 ◽  
Vol 1 (1) ◽  
pp. 23-31
Author(s):  
Abid H. Banday ◽  
Shameem A. Shah ◽  
Sheikh J. Ajaz
Keyword(s):  
Clinical Status ◽  
The United States ◽  
World Health ◽  
The Novel ◽  
Governmental Organizations ◽  
The World ◽  
Novel Coronavirus ◽  
Health Organization ◽  
Approved Drugs ◽  
Almost All

SARS-CoV-2, the novel coronavirus that was first reported in Wuhan, China in December 2019, has engrossed the world with immense distress. It has shattered the global healthcare system and has inflicted so much pain on humanity. COVID-19, the disease caused by a microscopic enemy, has now spread to almost all the countries in the world affecting millions of people and causing enormous casualties. World Health Organization (WHO) declared COVID-19 a pandemic on March 11, 2019. As of June 15, 2020, almost 7.70 million people have already been infected globally with 428,000 reported casualties. In the United States alone, 2.14 million people have been infected and 117,000 people have succumbed to this pandemic. A multipronged approach has been launched towards combating this pandemic with the main focus on exhaustive screening, developing efficacious therapies, and vaccines for long-term immunity. Several pharmaceutical companies in collaboration with various academic institutions and governmental organizations have started investigating new therapeutics and repurposing approved drugs so as to find fast and affordable treatments against this disease. The present communication aims at highlighting the efforts that are currently underway to treat or prevent SARS-CoV-2 infection through immunotherapy. Emphasis has been laid on discussing the approaches and platforms that are being utilized for the speedy development of therapeutic antibodies and preventive vaccines against SARS-CoV-2. The manuscript also presents a detailed discussion regarding strategy, clinical status, and timeline for the development of safe and enduring immunotherapy against SARS-CoV-2. All the details pertaining to the clinical status of each candidate have been last updated on June 15, 2020.

scholarly journals Coronavirus: Hotspot on coronavirus disease 2019 in India

2020 ◽  
Vol 72 ◽  
pp. 29-34 ◽  
Author(s):  
Rameshwar S. Cheke ◽  
Sachin Shinde ◽  
Jaya Ambhore ◽  
Vaibhav Adhao ◽  
Dnyaneshwar Cheke
Keyword(s):  
Respiratory Illness ◽  
World Health ◽  
Short Report ◽  
The Novel ◽  
Global Public Health ◽  
Health Crisis ◽  
Public Health Crisis ◽  
The World ◽  
Novel Coronavirus ◽  
Health Organization

The novel coronavirus disease (COVID-19) or also known as the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has been recognized as the cause of respiratory infection in Wuhan, Hubei Province, China, in late December 2019. As of April 5, 2020, this epidemic had spread to worldwide with 12,03,485 confirmed cases, including 62,000 deaths. The World Health Organization has declared it a Global Public Health Crisis. Coronavirus causes respiratory illness coughing, sneezing, breathlessness, and fever including pneumonia. The disease is transmitted person to person through infected droplets. At present, the research on novel coronavirus is still in the primary stage. Based on the published study, we thoroughly summarize the history and origin, microbiology and taxonomy, mode of transmissions, target receptor, clinical features, diagnosis, prevention, and treatment about COVID-19. This short report writes in hope for providing platform to community and researcher dealings against with the novel coronavirus and providing a reference for further studies.

SARS-COV2 virus and Coronavirus disease (COVID-19)

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 977-982
Author(s):  
Mohamed J. Saadh ◽  
Bashar Haj Rashid M ◽  
Roa’a Matar ◽  
Sajeda Riyad Aldibs ◽  
Hala Sbaih ◽  
...  
Keyword(s):  
Close Contact ◽  
Antiviral Agents ◽  
Health Concern ◽  
The Novel ◽  
Global Public Health ◽  
Fatal Disease ◽  
Mild Disease ◽  
Life Threatening ◽  
Novel Coronavirus

SARS-COV2 virus causes Coronavirus disease (COVID-19) and represents the causative agent of a potentially fatal disease that is of great global public health concern. The novel coronavirus (2019) was discovered in 2019 in Wuhan, the market of the wet animal, China with viral pneumonia cases and is life-threatening. Today, WHO announces COVID-19 outbreak as a pandemic. COVID-19 is likely to be zoonotic. It is transmitted from bats as intermediary animals to human. Also, the virus is transmitted from human to human who is in close contact with others. The computerized tomographic chest scan is usually abnormal even in those with no symptoms or mild disease. Treatment is nearly supportive; the role of antiviral agents is yet to be established. The SARS-COV2 virus spreads faster than its two ancestors, the SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV), but has lower fatality. In this article, we aimed to summarize the transmission, symptoms, pathogenesis, diagnosis, treatment, and vaccine to control the spread of this fatal disease.

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