scholarly journals Asymptomatic malaria and associated factors among blood donors in Mwanza, Tanzania

2017 ◽  
Vol 19 (2) ◽  
Author(s):  
Domenica Morona ◽  
Betrand Msemwa ◽  
Maria M. Zinga ◽  
Martha F. Mushi ◽  
Mariam M. Mirambo ◽  
...  

Background: Blood transfusion saves life of patients with severe anaemia. However, blood transfusion can transmit blood-borne parasites. Despite malaria being endemic in Tanzania, there is limited information on asymptomatic malaria among blood donors. This study determined the prevalence and associated factors of asymptomatic malaria among blood donors at the Lake Zone Victoria Blood Transfusion Centre in Mwanza, Tanzania.Methods: A cross-sectional study was conducted between March and April 2016 among blood donors without any symptoms of malaria. During blood donation, samples were collected from each participant. Malaria parasites were detected microscopically from Giemsa stained thin and thick smears and by the use of malaria rapid diagnostic test (MRDT).Results: A total of 150 blood donors participated in this study. The median age of participants was 20 (IQR: 18-27) years. Malaria prevalence by microscopy was 5.3% (95% CI: 1.7-8.8) while by MRDT was 8% (95% CI: 3.6-12.3). Malaria mean parasite density was 12mps/200WBC. Only individuals who reported using mosquito nets were found to be protected from getting asymptomatic malaria on multivariate logistic regression analysis (OR: 0.04, 95% CI: 0.01-0.25, P<0.001).Conclusion: A considerable proportion of blood donors in Mwanza, Tanzania are infected with P. falciparum which poses a risk for transmission to blood recipients including malaria vulnerable groups like pregnancy woman and children. Screening donated blood for malaria parasites is recommended in malaria endemic areas to prevent possible fatal consequences.

Author(s):  
Mentamir Abe ◽  
Mesafint Abeje Tiruneh ◽  
Kidanemariam Beyene

<p class="abstract"><strong>Background:</strong> Accessibility of a safe and adequate blood transfusion is a challenge worldwide and even more critical in Africa. Even though blood donation is lifesaving practice, current blood supply is far less compared to the demand in Ethiopia. However, there is limited information in Ethiopia. Therefore, this study aimed to assess blood donation practice and associated factors among health professionals working at heath center in Nefas Silk Lafto sub city, Addis Ababa, Ethiopia.</p><p class="abstract"><strong>Methods:</strong> Institution based cross-sectional study was conducted among health professionals working at health centers in Nefas Silk Lafto sub city, Addis Ababa from 23 August 2019 to 20 September 2019. Simple random sampling technique was used to select the study participants. Data were collected used self-administered structured questionnaire. Binary logistic regression analysis was used for data analysis.  </p><p class="abstract"><strong>Results:</strong> 459 health professionals were included in the study with a response rate of 98.4%. Only 157 (34.2%) of them donated blood in the last five years. Age (AOR=1.72, 95% CI: 1.06, 2.79), blood collection site (AOR=3.46, 95% CI: 2.03, 5.89), blood collection working (AOR=2.00, 95% CI: 1.16, 3.44) and knowledge (AOR=0.32, 95% CL: 0.14, 0.76) were significantly associated with blood donation practice.</p><p class="abstract"><strong>Conclusions:</strong> Blood donation practice was low. Age of health professionals, blood collection site, blood collection working hour and knowledge were significantly associated with blood donation practice. Therefore, establish fixed and mobile collection site and convenient time for blood donors and awareness creation is crucial.</p>


2019 ◽  
Vol 2 (1) ◽  
pp. 19-24
Author(s):  
O D Damulak ◽  
E D Jatau ◽  
E Ekam ◽  
E Rumji ◽  
R Yakubu ◽  
...  

Blood donation is not readily an altruistic sacrifice in sub-Saharan Africa where microbial infections, maternal haemorrhages, malaria and other tropical diseases that frequently require blood transfusion are daily diagnoses. Blood transfusion safety is hindered by the combined prevailing high rate of Transfusion-Transmissible Infections (TTIs) and poor screening techniques. This study determined the rate of Enzyme-Linked Immuno-Sorbent Assay (ELISA) positive reactions to transfusion-transmissible infections in rapid diagnostic test negative family replacement blood units, compared to the first time voluntarily donated blood. We studied records of blood units collected in a tertiary hospital from donors who scaled pre-donation Rapid diagnostic test (RDT) screening for the human immunodeficiency virus, hepatitis B and hepatitis C viruses and syphilis and rescreened by ELISA techniques at the National Blood Transfusion Service Centre in Jos, along with units from first-time voluntary blood donors. A total of 19562 blood units; 5945 (30.39%) rapid diagnostic tests negative from a linkage hospital and 13617 (69.61%) from first time voluntary donors were screened by ELISA methods for HIV, HBV, HCV, and syphilis. The overall TTIs detected by ELISA was 16.08%, significantly lower among pre-donation rapid screened family replacement blood donors [495(8.32%)] compared to 2651 (19.47%) among first-time voluntary donors; P=0.0001. Fifty-seven (0.96%) HIV, 166 (2.79%) HBV, 137 (2.31%) HCV and 137 (2.31%) syphilis were still detected respectively by ELISA in the pre-screened negative family replacement blood units. The outcome of ELISA screenings of blood collected from first-time volunteer donors were; 143 (1.05%) HIV, 1,486 (10.91%) HBV, 683 (5.02%) HCV, and 339 (2.49%) syphilis. Blood for transfusion should be screened negative at least with ELISA.


2020 ◽  
Vol 11 ◽  
Author(s):  
Songxu Peng ◽  
Xin Lai ◽  
Yukai Du ◽  
Yuting Li ◽  
Kunming Tian ◽  
...  

Background: The coronavirus disease 2019 (COVID-19) has been rapidly transmitted worldwide, which contributed to various psychological problems (such as fear, depression, and anxiety) among the general population in China. The purpose of this study is to investigate the prevalence and associated factors of depressive symptoms among Chinese adults.Methods: A cross-sectional study of Chinese adults was conducted during 17–29 February 2020. Symptoms of depression were assessed using the Center for Epidemiologic Studies Depression scale (CES-D).Results: A total of 3,399 respondents were included in the analysis. It was observed that 14.2% (481/3,399) of the participants were screened positive for depressive symptoms. In a multivariate logistic regression analysis, older age (OR = 0.98; 95% CI, 0.97–0.99), smoking (OR = 1.57; 95% CI, 1.10–2.26), self-rated health (good: OR = 0.49; 95% CI, 0.37–0.66; fairly: OR = 0.60; 95% CI, 0.45–0.80), having greater support scores (OR = 0.95; 95% CI, 0.94–0.96), knowledge about the main symptom of COVID-19 (very clearly: OR = 0.58; 95% CI, 0.42–0.79; relatively clearly: OR = 0.59; 95% CI, 0.44–0.79), and staying in Wuhan within 3 months before the outbreak of epidemic (OR = 1.78; 95% CI, 1.34–2.38) were associated with depressive symptoms.Conclusion: A considerable proportion of the general population in China had depressive symptoms during the COVID-19 epidemic. Routine screening and targeted interventions for depression are needed among high-risk depressed individuals during the COVID-19 epidemic.


2020 ◽  
Vol 14 (3) ◽  
pp. 1085-1092
Author(s):  
Djamalladine Mahamat Doungous ◽  
Abdelsalam Adoum Doutoum ◽  
Adawaye Chatte ◽  
Richard Laougangta Dounbe ◽  
Elysée Gondimo Gabdibe ◽  
...  

En Afrique subsaharienne, les infections transmissibles par la transfusion sanguine comme la syphilis sont très répandues, avec une prévalence pouvant atteindre 25% chez les donneurs de sang. La présente étude avait pour objectif de déterminer la prévalence de la syphilis chez les donneurs de sang au niveau de la Banque du Sang d’Abéché. Nous avons mené une étude transversale à visée descriptive, qui s’est déroulée de mai à août 2017. Les échantillons de sang des donneurs ont été testés par immunochromatographie pour la détection des anticorps anti-tréponémiques (Biomnis®). Sur 789 donneurs de sang inclus dans l’étude, la prévalence de la syphilis était de 4,9 %. Les donneurs étaient à 96,1% de sexe masculin et 3,9% de sexe féminin. Cette prévalence était plus élevée chez les sujets âgés de [21-30] ans, chez les femmes, les donneurs non scolarisés, divorcés et les domestiques/ménagères habitant la zone d’Abéché urbaine. Ces résultats montrent qu’il est nécessaire de mettre en place une politique de suivi et de prise en charge médicale des donneurs de sang atteints de la syphilis.Mots clés: Transfusion sanguine, receveurs, Treponema pallidum, don de sang.   English Title: Prevalence of syphilis in blood donors at Abéché blood bank in ChadIn sub-Saharan Africa, infections transmitted by blood transfusion such as syphilis are widespread, with prevalence up to 25% in blood donors. The purpose of this study was to determine the prevalence of syphilis in blood donors at the Blood Bank of Abéché. It was a descriptive cross-sectional study, which ran from May to August 2017. Donor blood samples were tested by immunochromatography for the detection of anti-treponemal antibodies (Biomnis®). Of the 789 blood donors included in the study, the prevalence of syphilis was 4.9%. Donors were 96.1% male and 3.9% female. This prevalence was higher in subjects aged [21-30] years, women, out-of-school, divorced and domestic / household donors living in the urban Abéché area. These results shows that it is necessary to set up a policy of monitoring and medical care of blood donors with syphilis.Keywords: Blood transfusion, recipients, Treponema pallidum, blood donation.


Author(s):  
Khaneta Parveen ◽  
Abdul F. Khan ◽  
Abdul S. Khan

Background: Blood donor base is the foundation of any blood transfusion system. Donor screening plays an important role in ensuring the safety of the blood supply.1 This study was undertaken with the aim to screen the blood donor’s demographic profile as male, female voluntary and replacement blood donors and to estimate seroprevalence of HIV, HBV, HCV and VDRL transmissible by blood transfusion in voluntary and replacement male and female blood donors during the last 5 year period.Methods: The present study was conducted over a period of 5 years (2001-2005) and involved 1,53,020 blood donors including both (voluntary, replacement males and females) who were thoroughly screened and selected for blood donation in blood bank at Departments of Pathology, Seth GS Medical College and KEM hospital, Mumbai. We determine among blood donors by their donor type (voluntary and replacement type) and gender wise.Results: The total number of blood donors in five years period was 1,53,020 (100%). Maximum number of voluntary  blood donors 1,00,316 (65.55%), followed by replacement blood donors 52,704 (34.33%).The overwhelming majority of donors in entire 5 years period was of male, comprising 1,36,195 (89.0%), while the female donors comprised of 16825 (10.99%).Conclusions: The maximum number of donors are voluntary males (55.69%) followed by replacement males (33.30%). Our results indicate that the number of female blood donors were less in comparison to male blood donors, so proper health education is required for female blood donors.


2006 ◽  
Vol 76 (3) ◽  
pp. 132-137 ◽  
Author(s):  
Mahmoud Djalali ◽  
Tirang R. Neyestani ◽  
Jamil Bateni ◽  
Fereydoun Siassi

Objective: Blood donation leads to substantial iron loss, as about 0.5 mg iron is lost per each milliliter of blood donated. If not compensated for efficiently, the iron loss may eventually lead to anemia, though non-anemic iron deficiency per se may be problematic. The aim of this study was to evaluate the effects of blood donation, and its frequency over a year’s time, on iron status of Iranian male blood donors attended blood transfusion stations of the Iranian Blood Transfusion Organization (IBTO). Design and setting: A cross-sectional, descriptive, and analytic study was conducted. 91 male volunteer blood donors aged from 20 to 50 years attending three IBTO stations located in central areas of Tehran, and 63 apparently healthy controls that were matched for age, gender, monthly income, height, and weight, were included in the study. Blood donors were divided into 4 groups according to the frequency of blood donation per year; i.e. 1, 2, 3, and 4 with 20, 30, 26, and 15 persons in each group, respectively. Just before blood donation, 10 mL venous blood sample was taken and divided into heparinized and non-heparinized tubes for determination of hemoglobin (Hb), hematocrit (Hct), serum iron (SI), total iron binding capacity (TIBC), ferritin, transferrin saturation (TS), and mean corpuscular hemoglobin concentration (MCHC). Dietary assessment was also done using 3 different questionnaires; i.e. general health, food frequency, and 24hr recall. Results: The levels of Hb, Hct, and iron status indices were all significantly lower in the subjects than in controls and a gradual but significant decrease in iron status indices in each time of blood donation was found. Serum ferritin showed significant correlations with age (r = 0.33, p < 0.001) and body-mass index (BMI) (r = 0.26, p = 0.03) only in the control group. Frequency of blood donation per year was also inversely correlated with Hb (r = -0.67, p < 0.001), Hct (r = -0.65, p < 0.001), MCHC (r = -0.56, p < 0.001), serum ferritin (r = -0.38, p < 0.001), SI (r = -0.62, p < 0.001), and TS (r = -0.61, p < 0.001), but was directly correlated with TIBC (r = 0.56, p < 0.001). Interestingly in blood donors, but not in healthy controls, serum ferritin levels showed weak but statistically significant correlations with daily intake of iron (r = 0.17, p < 0.05) and energy (r = 0.20, p = 0.03). Conclusion: Though repeated blood donations might diminish iron status, it could be safe to donate 2–3 U/year without an appreciable incidence of iron deficiency, provided that the pre-donation Hb and ferritin values are ≥ 14.7 g/dL and 58.9 μg/L, respectively. The male volunteers with Hb ≥ 14.2 g/dL and serum ferritin ≥ 57.2 μg/L could donate 1–2 U/year and those with Hb ≥ 13.1 g/dL and serum ferritin ≥ 35.3 μg/L could donate just once a year. Volunteers who undergo (repeated) blood donation should receive special nutritional care, especially in terms of iron and energy.


2021 ◽  
pp. 42-43
Author(s):  
Neha Patel ◽  
Sanjay Chaudhari ◽  
Sonal Chitroda

Background: India has the second highest HIV population in the world with about 2.5-3.0 million cases. Blood transfusion saves millions of lives worldwide each year but Blood transfusion is an important mode of transmission of infections to recipients and at the same time it is also associated with large number of complications including transfusion-transmissible infections (TTIs). Aims & objective: to study the prevalence of HIVin blood donors of A.D.Gorwala Blood bank From January 2005 To December 2010. Methods: A retrospective study was conducted among blood donors through the years 2005-2010. Sera from blood donors were tested for the detection of Anti HIV by using third generation ELISA tests, strictly following the instruction of manufacturers. The donor information was collected through the donor registers from A.D. Gorwala Blood Bank. Result: From the total of 28,371 screened blood samples collected, the prevalence of HIV in blood donors in the blood bank was 0.23% in the ve consecutive years but the trend of HIV infection has decreased from 2005(0.31%) to 2010 (0.04%). The age groups18-30 has the highest prevalence and the age group 51-60 was the lowest prevalence of HIV infection. The Prevalence of HIV among male (0.18%) was higher than in female donors (0.05%). The trend of HIVinfection was decreasing for both male and female blood donors. Conclusion: The analysis of HIV seroprevalence among blood donors through the year 2005- 2010 showed a signicantly decreasing trend, probably due to the cumulative effect of increasing awareness of HIVand improved screening system for safe blood donation.


2021 ◽  
Vol 1 (4) ◽  
pp. 383-393
Author(s):  
Sari Rahmada Mulyani ◽  
Aditya Aditya ◽  
Festy Ladyani Mustofa ◽  
Zulfian Zulfian

ABSTRACT: PREVALENCE OF POSITIVE HBsAg BETWEEN VOLUNTARY BLOOD DONATIONS AND REPLACEMENT BLOOD DONATIONS AT PMI UTD LAMPUNG PROVINCE 2019-2020 Background: The risk of transmission of HBV infection through blood transfusion depends on many things, including the prevalence of disease in the community, the recipient's immune status, the number of donors per unit of blood, and the effectiveness of the screening used. The main disease transmission will occur during the window period, which is a period immediately after infection in which the donor's blood has been infected but the screening result is still negative.Objective: To determine the prevalence of positive HBsAg between voluntary blood donations and replacement blood donations at the PMI UTD in Lampung Province in 2019-2020. Methodology: The type of research used in this research is quantitative descriptive with cross-sectional design. The sample used in this study were blood donors at UTD PMI Lampung Province in 2019-2020.Results: The prevalence of voluntary blood donation with positive HBsAg in 2019 was obtained as many as 70 people (33.65%) while the prevalence of replacement blood donors with positive HBsAg in 2019 was obtained as many as 8 people (16%). Then, the prevalence of positive HBsAg voluntary blood donors in 2020 was found to be 138 people (66.35%) while the prevalence of positive HBsAg blood donors in 2020 was 42 people (84%).Conclusion: There is a difference in the prevalence of both voluntary blood donors and replacement blood donors between 2019 and 2020. and the prevalence of HBsAg positive in blood donors is different every year. Keywords: Blood Transfusion, Volunteer, Replacement, HBsAg  INTISARI: PREVALENSI HBsAg POSITIF ANTARA DONOR DARAH SUKARELA DENGAN DONOR DARAH PENGGANTI DI UTD PMI PROVINSI LAMPUNG TAHUN 2019-2020 Latar Belakang: Risiko penularan pada infeksi HBV melalui transfusi darah bergantung pada banyak hal, antara lain yaitu adanya prevalensi penyakit pada masyarakat, status imun resipien, jumlah donor tiap unit darah dan keefektifan skrining yang di gunakan. Penularan penyakit yang utama akan timbul pada saat window period, yaitu suatu periode segera terjadi setelah terinfeksi dimana darah donor sudah terinfeksi tetapi hasil skrining masih negative.Tujuan: Mengetahui Prevalensi HBsAg Positif Antara Donor Darah Sukarela Dengan Donor Darah Pengganti Di UTD PMI Provinsi Lampung Tahun 2019-2020.Metodologi: Jenis penelitian yang digunakan dalam penelitian ini adalah deskriptif kuantitatif dengan desain cross sectional. Sampel yang digunakan pada penelitian ini adalah pendonor darah di UTD PMI Provinsi Lampung tahun 2019-2020.Hasil: Prevalensi donor darah sukarela dengan HBsAg positif pada tahun 2019 didapatkan sebanyak 70 orang (33,65%) sementara prelavensi donor darah pengganti dengan HBsAg positif pada tahun 2019 didapatkan sebanyak 8 orang (16%). Lalu, prevalensi donor darah sukarela dengan HBsAg positif pada tahun 2020 didapatkan sebanyak 138 orang (66,35%) sementara untuk prevalensi donor darah pengganti dengan HBsAg positif pada tahun 2020 didapatkan sebanyak 42 orang (84%).Kesimpulan: Terdapat perbedaan prevalensi baik donor darah sukarela maupun donor darah pengganti antara tahun 2019 dengan tahun 2020. Dan prevalensi HBsAg Positif pada donor darah berbeda-beda setiap tahun. Kata Kunci     : Donor Darah, Sukarela, Pengganti, HBsAg


2021 ◽  
Vol 8 (29) ◽  
pp. 2615-2619
Author(s):  
Indu Pachampully Kumaran ◽  
Archana K.A ◽  
Meena Dharmadas ◽  
Sasikala Nadanganan ◽  
Anu Kumar B ◽  
...  

BACKGROUND Even in the presence of sufficient voluntary blood donors, the need of blood is not met yet. We wanted to evaluate the causes that hinder the smooth functioning of well-maintained blood transfusion services (BTS). METHODS This is a population based cross-sectional study conducted among blood donors from voluntary outreach blood donation camp for period of one year. Total 1536 blood donors from 32 blood donation camps were subjected to study for the sociodemographic characteristic and their knowledge of blood donation. Statistical analysis of data was done using Microsoft Excel, analysed using statistical package for social sciences (SPSS) ver.16 software. RESULTS A total of 32 blood donation camps were conducted during the study period that provided 1536 donors. In most of the camps, male donors (75 %) were more than female donors. Donors of age group of 30 to 39 years (43.9 %) were more when compared to others. Donors those who were married accounted for 79.9 %. Blood donors of Hindu religion (53 %) were more. CONCLUSIONS The main hindrance for blood donor motivation is lack of knowledge. Literacy and chance to mingle in society have a positive effect on blood donor motivation. Targeting of effective donor motivation, recruitment, and retention were attained by conducting awareness classes, seminars, workshops, and visual communication modalities. KEYWORDS World Health Organization, Altruistic Blood Donor, Blood Transfusion Services, Transfusion Transmitted Infections, Blood Components and Plasma Derivatives, Director General of Health Services (DGHS), National Blood Transportation Council (NBTC)


2013 ◽  
Vol 3 (6) ◽  
pp. 459-463 ◽  
Author(s):  
S Mangwana

Background: Hemovigilance like quality systems and audits have become an integral part of Blood Transfusion Services in the developed countries and has contributed greatly to its development. Hemovigilance begins with donors and must enable the collection of information on reactions occurring during the donation of blood, selections of donors and to prevent such incidents. The aim of study was to help identify the trends of adverse events , occurring in blood donors at a tertiary-care hospital, to recommend best practices to improve donor care and safety Materials and Methods: This record-based study was conducted on all adverse events related to allogenic whole blood donations performed over 24 months. All whole blood donations were analyzed. All adverse events occurring during or at the end of the donation were noted using a standardized format and analyzed determining significance at p<0.05. Results: Overall rate was 0.3% with vasovagal reactions constituting 82%, and 18% mild syncopal reactions (p<0.001). Immediate vasovagal reaction with injury was very rare (0.007%). Vasovagal reactions showed a significant association with young age, female gender, first time donation status. Mean age of persons recording adverse effects was 30.23 ± 7.49 years as compared to those without adverse effects, 31.14 ± 8.56 years. Conclusion: Donor safety is an essential perquisite to increase voluntary blood donation. AE analysis helps in identifying the blood donors at risk of AE, applying appropriate motivational strategies, predonation counseling, care during and after donation, developing guidelines and hemovigilance programme in countries with limited resources. DOI: http://dx.doi.org/10.3126/jpn.v3i6.8993   Journal of Pathology of Nepal (2013) Vol. 3, 459-463


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