scholarly journals Clinical and Endoscopic Profile of Patients with Uninvestigated Dyspepsia: Experience from a Single Center

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Syed Shafiq ◽  
Rajkumar P Wadhwa

Background: Dyspepsia is undoubtedly one of the most common complaints that primary care physicians and gastroenterologists encounter in their clinical practice and encompasses a constellation of symptoms localized to the upper abdomen. While majority of these patients have “functional dyspepsia” with no endoscopic abnormality to account for their symptoms, benign conditions such as peptic ulcer disease and reflux esophagitis are the most common endoscopic lesions noted in “organic dyspepsia.” Aim: The aim of the study was to study the clinical and endoscopic profile of patients presenting with uninvestigated dyspepsia (patients with new or recurrent dyspeptic symptoms in whom no investigations have previously been undertaken) at our center. Materials and Methods:: A hospital-based retrospective observational study which included both inpatient and outpatient population over a period of 2 years, from December 2014 to November 2016. Patients’ charts from our hospital database were reviewed and data with regard to demographic variables, clinical and endoscopic profile of patients with uninvestigated dyspepsia was analyzed. Results A total of 280 patients with uninvestigated dyspepsia underwent esophagogastroduodenoscopy (EGD). The mean age of our study population was 45.2 years with 162 (58%) male and 118 (42%) female patients. The most common symptom was post-prandial fullness seen in 132 patients (47%). Endoscopy was reported as normal in 179 patients (64%) while 101 patients (36%) had an abnormal endoscopic finding with duodenal ulcer being the most common endoscopic abnormality (7.9%), followed by erosive gastritis (6.7%), reflux esophagitis (6.1%), gastric ulcer (3.9%), varioliform gastritis (3.2%), and esophageal/gastroesophageal junction malignancy (2.85%). Elderly (?50 years) patients with alarm symptoms such as weight loss, dysphagia, and/or anemia had a higher incidence of malignancy. Conclusion About two-thirds (64%) of our study population had functional o

Author(s):  
V.B.P. Suryakumari ◽  
Y. Pallavi Reddy ◽  
Sarjeev Singh Yadav ◽  
Dolar Doshi ◽  
V. Surekha Reddy

ABSTRACT Objective: Originating in China in December 2019, coronavirus disease 2019 (COVID-19) rapidly spread to more than 216 countries in the world by May 2020. Because dentists are at a higher risk of contracting the disease, the present study assessed the fear and anxiety among dental practitioners of becoming infected with COVID-19. Methods: An online cross-sectional questionnaire survey comprising of 9 questions was conducted among dental practitioners of Telangana. Age, gender, qualification, type of practice, years of practice, and place of residence were the demographic variables recorded. The response to each question was recorded in a YES or NO format, and mean fear score was calculated to categorize answers into low and high levels of fear. Comparison of mean fear score was done using t-test for 2 variables and analysis of variance for 3 or more than 3 variables. Multiple logistic regression analysis of the levels of fear with demographic variables was done. P < 0.05 was considered statistically significant. Results: The mean fear and anxiety score of this study population reported was high 6.57 ± 2.07, with 58.31% of the population presenting with a low level of fear and anxiety. Only qualification (P = 0.045) and gender (P = 0.035) revealed a significant difference in fear to Q7and Q8, respectively. Irrespective of the age, gender, qualification, type of practice, and years in practice, the levels of fear reported in the present study were very similar. Respondents between 41 and 60 y of age (6.70 ± 2.01 y) and those with individual practices (6.70 ± 2.06 y) exhibited high fear scores. Conclusions: The present study demonstrates cross-sectional data of fear and anxiety among dental practitioners during the COVID-19 outbreak. Heightened levels of fear observed in this study call for a nationwide analysis of fear among dentists and deliberate management strategies for the same.


Author(s):  
Arvind Kumar B. Sangavi ◽  
Basavaraj Peerapur ◽  
Nirmita Gummadi

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Otomycosis is a fungal infection of the ear canal. It is mostly seen in hot and humid climatic conditions of the tropical and subtropical countries. It can also occur as a result of decreased immunity (and has been seen as a common occurrence as an opportunistic infection in the immunocompromised). </span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">Patients clinically diagnosed with otomycosis and coming to the ENT department RIMS teaching hospital were first subjected to detailed history taking. The samples from ear will then be collected by three sterile cotton swabs and sent to Microbiology Department, RIMS. Fungal, bacterial cultures were performed and microscopic examination was done.  </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">Patients presented with a wide age range, the youngest patient being 6 months old and eldest being 28.31 years old. The mean age of the study population was 28.31 years. The ratio between male and female patients was 1.13:1 with male predominance. There were 26 patients (81.2%) who had a habit of using pins or sticks. The chief complaints of majority of the patients were pain and itching. Pain ranged from mild to severe type. Least common symptom was tinnitus. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">In our study male predominance was seen and majority of cases were unilateral. There were only 5 patients who were immunocompromised. The most common presenting symptom was pain and itching. There were 81.2% patients who had a habit of using pins/ sticks.</span></p>


2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Eman Sobh ◽  
Fatma Elhussieny ◽  
Taghreed Ismail

Abstract Background Nasal obstruction is a significant medical problem. This study aimed to examine the effect of nasal obstruction and nasal packing on arterial blood gases and pulmonary function indices, and the impact of the elimination of nasal obstruction on preoperative values. Results The mean age of the study population was 26.6 ± 10.1 years, males represented 50.8%. Spirometric indices showed statistically significant improvement (preoperative forced expiratory volume in 1st second 66.9 ± 13.9 vs 79.6 ± 14.9 postoperative and preoperative forced vital capacity 65.5 ± 12.7 vs 80.4 ± 13.8 postoperative). Oxygen saturation was significantly lower during nasal packing (95.6 ± 1.6 preoperative vs 94.7 ± 2.8 with nasal pack), and significant improvement (97.2 ± 1.4) was observed after removal of the nasal pack. Nasal obstruction scores significantly improved. Conclusion The results of this study indicate that either simple nasal obstruction or nasal packing may cause hypoxemia and abnormalities in lung function tests. Hypoxemia was more evident with nasal packing.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ahmad Baihaqi Azraii ◽  
Anis Safura Ramli ◽  
Zaliha Ismail ◽  
Suraya Abdul-Razak ◽  
Siti Fatimah Badlishah-Sham ◽  
...  

Abstract Background Primary care physicians (PCP) play an important role in detecting Familial Hypercholesterolaemia (FH) early. However, knowledge, awareness and practice (KAP) regarding FH among Malaysian PCP are not well established, and there was no validated tool to assess their FH KAP. Thus, the aim of this study was to adapt an FH KAP questionnaire and determine its validity and reliability among Malaysian PCP. Methods This cross-sectional validation study involved Malaysian PCP with ≥ 1-year work experience in the primary care settings. In Phase 1, the original 19-item FH KAP questionnaire underwent content validation and adaptation by 7 experts. The questionnaire was then converted into an online survey instrument and was face validated by 10 PCP. In Phase 2, the adapted questionnaire was disseminated through e-mail to 1500 PCP. Data were collected on their KAP, demography, qualification and work experience. The construct validity was tested using known-groups validation method. The hypothesis was PCP holding postgraduate qualification (PCP-PG-Qual) would have better FH KAP compared with PCP without postgraduate qualification (PCP-noPG-Qual). Internal consistency reliability was calculated using Kuder Richardson formula-20 (KR-20) and test–retest reliability was tested on 26 PCP using kappa statistics. Results During content validation and adaptation, 10 items remained unchanged, 8 items were modified, 1 item was moved to demography and 7 items were added. The adapted questionnaire consisted of 25 items (11 knowledge, 5 awareness and 9 practice items). A total of 130 out of 1500 PCP (response rate: 8.7%) completed the questionnaire. The mean percentage knowledge score was found to be significantly higher in PCP-PG-Qual compared with PCP-noPG-Qual (53.5, SD ± 13.9 vs. 35.9, SD ± 11.79), t(128) = 6.90, p < 0.001. The median percentage awareness score was found to be significantly higher in PCP-PG-Qual compared with PCP-noPG-Qual (15.4, IqR ± 23.08 vs. 7.7, IqR ± 15.38), p = 0.030. The mean percentage practice score was significantly higher in PCP-PG-Qual compared with PCP-noPG-Qual (69.2, SD ± 17.62 vs. 54.4, SD ± 19.28), t(128) = 3.79, p < 0.001. KR-20 value was 0.79 (moderate reliability) and average Kappa was 0.796 (substantial agreement). Conclusion This study has proven that the 25-item adapted FH KAP questionnaire is valid and reliable. It can be used to measure and establish FH KAP among PCP in Malaysia.


2018 ◽  
Vol 4 (2) ◽  
pp. 69-74
Author(s):  
Md Tauhidul Islam Chowdhury ◽  
Mohammad Shah Jahirul Hoque Choudhury ◽  
KM Ahasan Ahmed ◽  
Mohammad Sadekur Rahman Sarkar ◽  
Md Abdullah Yusuf ◽  
...  

Background: Neurological disorders is becoming a growing concern both for developed and developing countries. Magnitude of the problem is increasing day by day. Among all neurological disorders, stroke is the leading cause of morbidity and mortality globally.Objectives: The purpose of the study was to see the trend of admission of patients with neurological diseases and to study the outcome of patients at referral neurology hospital in Bangladesh.Methodology: This retrospective chart review was conducted in the blue unit of the Department of Neurology at National Institute of Neurosciences and Hospital, Dhaka, Bangladesh from 1st January to 31st December 2016 for a period of one (01) year. All the admitted patients with both sexes were selected as study population. The outcome was observed among the study population.Result: A total number of 1044 patients were admitted during the study period. Majority of the patients were in the age group of the 41 to 50 years which was 417(39.9%) cases. Both male and female were in highest number in the month of May which was 63 and 48 cases respectively. The total death of the study population was 146(14.0%) cases. The mean length of hospital stay was 8.4±2.31 days.Conclusion: Middle aged male is the main bulk of the neurological patients, admitted in a referral neurology hospital in Bangladesh. Highest admission and mortality was observed in stroke patients.Journal of National Institute of Neurosciences Bangladesh, 2018;4(2): 69-74


2010 ◽  
Vol 2010 ◽  
pp. 1-3 ◽  
Author(s):  
Talvensaari-Mattila Anne ◽  
Turpeenniemi-Hujanen Taina

Background. The role of matrix metalloproteinase-2 and -9 (MMP-2, MMP-9) in matrix degradation and metastasis has been described in various tumors. Their action is inhibited by their natural tissue inhibitor molecules TIMP-1 and -2.Methods. The study population consisted of 12 squamous cervical carcinoma patients and 27 healthy volunteer control patients. MMP-9, MMP-2-TIMP-2 complex, TIMP-1, and TIMP-2 were analyzed from serum samples using enzyme-linked immunoassay (ELISA).Results. The mean levels of serum TIMP-2 and of MMP-2-TIMP-2 complex were higher in healthy controls compared to patients with a malignant tumor. Serum TIMP-2 values decreased significantly from healthy controls (median 323 g/l, range 305–342 g/l) to malignant (median 136 g/l, range 120–151 g/l) squamous cervical carcinoma patients . Also, serum proMMP2-TIMP2 complex values decreased from control patients to squamous cervical carcinoma patients .Conclusion. This paper shows that the levels of circulating TIMP-2 and that of MMP-2-TIMP-2 complex are lower in squamous cervical carcinoma patients than in healthy women.


2018 ◽  
Vol 76 (11) ◽  
pp. 751-755 ◽  
Author(s):  
Gabriela G. M. Balbi ◽  
Sandro L. Matas ◽  
Claudio A. Len ◽  
Melissa M. Fraga ◽  
Iggor O. Sousa ◽  
...  

ABSTRACT Objective: To report cases of children and adolescents diagnosed with pseudotumor cerebri associated or not with rheumatic disease. Methods: This was a retrospective study based on medical reports of 29 patients, up to 18 years of age and diagnosed with pseudotumor cerebri, followed up in the Pediatric Rheumatology and Neurology outpatient clinics of a tertiary hospital, until December 2016. Results: Among the 29 patients diagnosed with pseudotumor cerebri, 51.7% were girls and the mean age at the disease onset was 12.3 years. In 18 patients (62%) where an etiology was found, four were associated with a rheumatic disease. The most common symptom was headache (69%) and acetazolamide was the most used medication (69%). Two patients developed blindness and 10 are still being followed up. Conclusion: Although rare, pseudotumor cerebri should be considered in children with headaches, especially in patients with rheumatic disease.


2021 ◽  
Vol 11 (1) ◽  
pp. 4-6
Author(s):  
Muhammad Alam Sikder ◽  
Tasneem Faruqui ◽  
KM Abdullah Al Harun ◽  
Sajjad Mahmud ◽  
Radia Faruqui

This cross sectional study on oral condition among school going children in Sylhet city was conducted at Osmani Medical High School, Dorgah Gate, Sylhet, Bangladesh. This study was carried out on 8th October, 2019 among 208 students, mostly 12 years aged studying in Class VI. The main objective of the study was to assess the oral health condition of school going children through decayed, missing, and filled teeth (DMFT) status. Data was collected by personal interview and clinical examination of the respondents. Among 208 children, 96 (46.2%) were boys and 112 (53.8%) were girls. Among all, 63 (30.3%) respondents brush their teeth once daily while 137 (65.9 %) respondents brush twice a day, and 8 (3.8 %) of them brush their teeth more than twice daily. Fluoride containing toothpaste is used by 73 (35.1 %) students, 112 (53.8 %) students did not know whether their toothpaste contain fluoride or not, and 23 (11.1 %) students do not use fluoride. Among all respondents, 125(60.09 %) did not have any decayed tooth, while 83(39.90 %) had tooth decay, and 20(9.6 %) had their teeth filled. Normal gingival condition was found in 185 (88.94 %) subjects, but 23(11.06 %) of them had red or swollen gingiva. The mean DMFT of the study population was 1.19 which is considered as “low” according to “WHO quantification for the DMFT index”. Update Dent. Coll. j: 2021; 11 (1): 4-6


2018 ◽  
Vol 5 (5) ◽  
pp. 1143
Author(s):  
P. K. Bariha ◽  
K. M. Tudu ◽  
Shiny Thomas Kujur

Background: The microvascular and macrovascular complications in diabetes mellitus resulting in microalbuminuria and diabetic neuropathy in common in developing country like India. The aim of the study has been undertaken to emphasis upon the association of microalbuminuria with neuropathy.Methods: The study was undertaken among 124 Type-II diabetes patients in the Department of Medicine, VIMSAR, Burla, Odisha between October 2015 to September 2017. Detail history, clinical examination, BMI, laboratory investigation like FBS, PPBS, HbA1C, nerve conduction study was done, and data were analysed and compiled.Results: Out of 124 patients the mean age of male patients in the study was 49.75 years and that of female patients was 50.36 years. The mean age of the study population was 50.18 years. The mean BMI in patients with and without microalbuminuria was 23.95±2.04kg/m2 and 21.57±2.89kg/m2 respectively. The mean HbA1C value in patients with and without microalbuminuria was 9.96±3.380 and 8.75±3.25 respectively.Conclusions: Microalbuminuria is significantly associated with presence of neuropathy. The most common type of neuropathy observed in this study was distal symmetrical sensory motor neuropathy. Hence, microalbuminuria has an important role as a biochemical marker for risk factor evaluation of microvascular complications in type 2 diabetes mellitus.


2019 ◽  
Vol 7 (2) ◽  
pp. 91-98
Author(s):  
Agata Gaździńska ◽  
Paweł Jagielski ◽  
Robert Gałązkowski

The aim: Assessment of physical activity of members of the Helicopter Emergency Medical Service. Material and methods: The study was conducted in a group of 131 people (65 paramedics, 66 pilots), members of HEMS teams from all bases in Poland, aged 27-59. The characteristics of physical activity was obtained using the author’s questionnaire. Results: The mean age of the study population was 42.73 ± 9.58 years. Pilots were significantly older than paramedics and had significantly higher BMI values (p < 0.05). No significant relationship between the age and BMI in the analyzed groups was found (p > 0.05), while the relationship between the frequency of physical activity and BMI was demonstrated. 70% of subjects undertook physical activity less than three times a week. The most frequently chosen forms were cycling, walking and swimming. Paramedics statistically significant more often than pilots chose wall climbing (p = 0.001). Downhill skiing (61%) was the most common declared winter sport played by pilots, while hiking in the mountains – by paramedics (49%). The most important reason for pilots to take up physical activity was concern for their health (47%), while for paramedics – the pleasure (63%). Paramedics statistically significant more often than pilots indicated a large number of other activities (90.6 vs. 74.2%) and financial issues (18.8 vs. 6.1%) as barriers that prevented more involvement in physical activities. Conclusions: The frequency of physical activity undertaken by HEMS members is insufficient. Low physical activity of HEMS team members has an adverse effect on their nutritional status. It is necessary to take initiatives to promote physical activity in this professional group.


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