scholarly journals ИНДИВИДУАЛЬНАЯ ПРЕДРАСПОЛОЖЕННОСТЬ К ДЕЙСТВИЮ ПРОИЗВОДСТВЕННО-ЭКОЛОГИЧЕСКИХ БИОЛОГИЧЕСКИХ ФАКТОРОВ У ГОРНОРАБОЧИХ ПО АЛЛОАНТИГЕННЫМ ТКАНЕВЫМ СТРУКТУРАМ

2021 ◽  
Vol 7 (5(59)) ◽  
pp. 16-18
Author(s):  
Б.Т. ЧЕРГИЗОВА ◽  
П.А. ШАРИПОВА ◽  
М.А. АТАХОДЖАЕВА ◽  
И.А. ИШИГОВ ◽  
Д.Н. ИМАНОВА
Keyword(s):  
Comparative Analysis ◽  
Individual Differences ◽  
Genetic Polymorphism ◽  
Genetic Markers ◽  
Occupational Diseases ◽  
Preventive Measures ◽  
The Body ◽  
Individual Sensitivity ◽  
Production Factors ◽  
Pathogenic Agents

This article provides a comparative analysis of individual differences in the development of occupational diseases, which are based on human genetic polymorphism. The genetic systems of the body take part in the formation of chronic diseases in mining workers exposed to the complex effects of harmful production factors and determine individual sensitivity to pathogenic agents. The study of genetic markers allows us to justify the criteria for professional selection and to conduct more effective preventive measures.

scholarly journals Role of genetic polymorphism and differences in the detoxification of chemical substances in the human body

2019 ◽  
Vol 95 (3) ◽  
pp. 255-262 ◽  
Author(s):  
Lyubov A. Mogilenkova ◽  
V. R. Rembovskiy
Keyword(s):  
Genetic Polymorphism ◽  
Genetic Markers ◽  
Human Body ◽  
Individual Sensitivity ◽  
Chemical Substances ◽  
Hazardous Chemical ◽  
Xenobiotic Biotransformation

There are given modern views on the role of genetic polymorphism on the detoxification of chemical substances and individual sensitivity in workers to the development of diseases associated with xenobiotics metabolism disorders. In the search for genetic markers of occupationally caused diseases it is promising to study allelomorphs of genes responsible for the polyfunctional response of the human body, including genes involved in xenobiotic biotransformation. There is substantiated the expediency of compilation and introduction of genetic passports for stuff occupied at hazardous chemical enterprises.

ASSESSMENT OF THE SENSITIVITY OF THE HUMAN ORGANISM TO THE EFFECT OF ELECTROMAGNETIC RADIATION OF RADIO FREQUENCY RANGE

2017 ◽  
Author(s):  
Liubov Sergeeva ◽  
◽  
Oleksandr Valchenko ◽  
Viktoriia Sergeeva ◽  
Oleksandr Koval ◽  
...  
Keyword(s):  
Comparative Analysis ◽  
Radio Frequency ◽  
Electromagnetic Radiation ◽  
Human Body ◽  
The Body ◽  
Human Organism ◽  
Frequency Range ◽  
Individual Sensitivity ◽  
Screening Procedures ◽  
The Individual

The implementation of the effects of any electromagnetic radiation depends on the individual sensitivity of the human body. To determine the criteria for assessing the individual sensitivity of the human body to the action of non-ionizing electromagnetic radiation in the radio frequency range (EMF RF-range), medical examination, anthropometric and physiological parameters, screening procedures of Beyton, Shmishek, orthostatic tests and other peripherals were performed. After a survey and questionnaire of students, which indicated how many years they used IT-technologies, a comparative analysis of the pre- nosological manifestations of adverse effects on the body of EMR RF.

Individual Differences in the Flexibility of Peripersonal Space

2017 ◽  
Vol 64 (1) ◽  
pp. 49-55 ◽  
Author(s):  
Samuel B. Hunley ◽  
Arwen M. Marker ◽  
Stella F. Lourenco
Keyword(s):  
Individual Differences ◽  
Peripersonal Space ◽  
The Body ◽  
Laser Pointer ◽  
Baseline Measure ◽  
Bisection Task ◽  
Defensive Function ◽  
Representational Space ◽  
Laser Condition ◽  
Line Bisection Task

Abstract. The current study investigated individual differences in the flexibility of peripersonal space (i.e., representational space near the body), specifically in relation to trait claustrophobic fear (i.e., fear of suffocating or being physically restricted). Participants completed a line bisection task with either a laser pointer (Laser condition), allowing for a baseline measure of the size of one’s peripersonal space, or a stick (Stick condition), which produces expansion of one’s peripersonal space. Our results revealed that individuals high in claustrophobic fear had larger peripersonal spaces than those lower in claustrophobic fear, replicating previous research. We also found that, whereas individuals low in claustrophobic fear demonstrated the expected expansion of peripersonal space in the Stick condition, individuals high in claustrophobic fear showed less expansion, suggesting decreased flexibility. We discuss these findings in relation to the defensive function of peripersonal space and reduced attentional flexibility associated with trait anxieties.

Bovine hypodermatosis in Stavropol region: distribution, pathogenesis, veterinary and sanitary assessment of slaughter products

2020 ◽  
pp. 7-10
Author(s):  
Vasiliy P. Petropavlovsky ◽  
◽  
Vyacheslav V. Marchenko ◽  
Lyudmila S. Vikulova ◽  
Olga D. Chepeleva ◽  
...  
Keyword(s):  
Preventive Measures ◽  
Climatic Conditions ◽  
The Body ◽  
Erythrocyte Aggregation ◽  
Economic Damage ◽  
Hydropic Degeneration ◽  
Hypoderma Lineatum ◽  
Hypoderma Bovis ◽  
Stavropol Region ◽  
Histomorphological Changes

Summary. Data on distribution of hypodermatosis among large horned cattle in Stavropol region are presented in the article. It was proved that this pathology is widespread in this region. From 12% to 38% of animals from the total number of examined livestock are affected. Ordinary subcutaneous botfly (stroma) Hypoderma bovis de Geer and south subcutaneous botfly (pischevodnik) Hypoderma lineatum de Villers parasites on large horned cattle. The species ratio of gadflies is: Hypoderma bovis (de Gee - 61.1%, Hypoderma lineatum de Villers - 38.9%). The disease is widespread in all climatic zones of Stavropol region. Animals of all age and sex groups are infected, but young animals are more often affected. Linear relationship between the indicators of the transformation of climatic conditions in Stavropol region, the spread of hypodermatosis and the timing of treatment and preventive measures were determined. Authors proved that the complete death of H. bovis and H. lineatum imago (regardless of the time of their hatching) was noted when the temperature drops to -3°C for two days. Thus, this temperature determines the start of treatment and preventive measures against hypodermatosis in the area of animal welfare. When analyzing the histomorphological changes caused by H. bovis and H. lineatum in the body of large horned cattle, perforation of the skin, swelling of adjacent tissues, disorganization of the stroma and structural elements, erythrocyte aggregation, hemorrhages, hydropic degeneration of cellular elements, tissue necrosis, polymorphonuclear leukocyte infiltration of affected organs and tissues were observed. The data on pathogenesis were presented, the analysis of economic damage and the veterinary and sanitary assessment of the products of slaughter of cattle with hypodermatosis were carried out.

Gender differences in biochemical measurement reflecting the state of free-radical oxidation and antioxidant protection among workers in metallurgical production

2019 ◽  
Vol 1 (10) ◽  
pp. 877-881
Author(s):  
I. A. Umnyagina ◽  
L. A. Strakhova ◽  
T. V. Blinova
Keyword(s):  
Oxidative Stress ◽  
Gender Differences ◽  
Free Radical ◽  
Biochemical Parameters ◽  
Free Radical Oxidation ◽  
The Body ◽  
Antioxidant Protection ◽  
Radical Oxidation ◽  
Metallurgical Production ◽  
Production Factors

Introduction. To date, age and sex differences have been established for many biochemical parameters. Gender differences in indicators for systems such as antioxidant, thiol-disulfide, oxidative stress and inflammation systems are absent or under study.The aim of the study was to identify gender differences in biochemical parameters reflecting the functioning of antioxidant systems of the body and free radical oxidation in workers of metallurgical production, in contact with harmful production factors.Materials and methods. The blood of men and women working at the metallurgical enterprise of the Nizhny Novgorod region (n=80) under the influence of a complex of physical and chemical production factors was studied. Total oxidative stress, total antioxidant capacity of serum, glutathione levels were studied by photometric biochemical methods. Levels of C-reactive protein and 8-hydroxy–2-deoxyguanosine were studied by ELISA.Results. The average amount of peroxides in the serum of women exceeded 1.6 times this figure in men. In the group of men, the content of 8-Ondg was higher by 26% (p=0.012), the level of GS-by 12% (p=0.019), the activity of SOD — by 1.5–2 times (p=0.0001), the level of CRP — by 2 times (p=0.008) compared to similar indicators in women.Conclusions. Studies of gender differences in workers under the influence of harmful production factors will allow more effective approach to the etiology, treatment and prognosis of production-related diseases. Indicators of oxidative stress and antioxidant protection can be indicators of the health of workers under the influence of harmful industrial factors and be important in the prevention of diseases associated with oxidative stress.

Molecular genetic markers for assessing individual sensitivity to lead

2019 ◽  
Author(s):  
Л.П. Кузьмина ◽  
◽  
А.Г. Хотулева ◽  
М.М. Коляскина ◽  
Л.М. Безрукавникова ◽  
...  
Keyword(s):  
Genetic Markers ◽  
Molecular Genetic ◽  
Individual Sensitivity ◽  
Molecular Genetic Markers

Current trends in the development of isotonic drinks for athletes

2021 ◽  
pp. 311-317
Author(s):  
N.M. Podgornova ◽  
A.R. Zainutdinova
Keyword(s):  
Comparative Analysis ◽  
Fluid Balance ◽  
Consumer Preferences ◽  
The Body ◽  
Sucrose Content ◽  
Current Trends ◽  
High Sucrose

The article reflects the importance of isotonic drinks to maintain optimal fluid balance and replace the loss of electrolytes in the body of athletes. Consumer preferences are studied, and a comparative analysis of some isotonic drinks is presented. It has been established that the majority of isotonic agents have artificial colors, preservatives, and high sucrose content, the excessive use of which leads to the formation of various kinds of diseases.

How to detect occupational diseases associated with the exposure to chemical factors

2020 ◽  
pp. 26-35
Author(s):  
Sergey Babanov
Keyword(s):  
Urinary Tract ◽  
Occupational Diseases ◽  
Educational Institution ◽  
Physical Nature ◽  
Federal State ◽  
Physical Factors ◽  
Ministry Of Health ◽  
Production Factors ◽  
Chemical Factors ◽  
Medical University

Diseases of the kidneys and urinary tract, primarily of toxic and chemical etiology, constitute a large proportion of occupational diseases. Various production factors of both chemical and physical nature can cause the development of nephropathies. Sergey Babanov, Doctor of Medicine, Professor, Head of the Department of occupational diseases and clinical pharmacology at the Federal State-Funded Educational Institution of Higher Education Samara State Medical University of the Ministry of Health of the Russian Federation, chief freelance specialist in occupational pathology at the Ministry of Health of the Samara region, speaks about occupational diseases of the kidneys and urinary tract associated with the exposure to chemical and physical factors.

Increased severity of labor is the most important risk factor of occupational diseases at enterprises in the Arctic

2020 ◽  
pp. 26-34
Author(s):  
S.A. Syurin
Keyword(s):  
Occupational Diseases ◽  
Cumulative Effect ◽  
Occupational Exposures ◽  
The Arctic ◽  
Physical Factors ◽  
Mining Operations ◽  
Production Factors ◽  
Permissible Levels ◽  
The Russian Federation ◽  
Total Structure

In Russia, in the structure of harmful production factors that cause the development of occupational pathology, the severity of labor takes the second place. The aim of the study was to investigate the effect of increased labor severity on the occurrence, prevalence and structure of occupational diseases in workers at enterprises in the Arctic. The analysis included results of the monitoring study “Working conditions and occupational morbidity” of the population of the Arctic zone of Russia in 2008 – 2018. It was found that in 2008-2018 there was a significant increase in the etiological significance of increased labor severity in the development of occupational pathology: the share of the factor in the total structure of harmful occupational exposures increased from 7.4% to 8.9% (p <0.001), and that of occupational diseases caused by increased labor severity - from 18.6% to 46.9% (p <0.001). Two thirds of occupational diseases caused by the increased severity of labor occur in miners, and diseases of the musculoskeletal system dominate in their structure (80.1%). The risk of developing this group of occupational health disorders in 2018 was higher than in 2008: RR=3,95; CI 3,13-4,99; χ2 =155,9; р<0,001. In contrast to the Russian Federation as a whole, where the increased severity of labor ranks second among the occupational pathology causing factors (24.7%), in the Russian Arctic it came out on top in 2018 (46.9%), exceeding the cumulative effect of all physical factors (44.0%). When carrying out recreational activities and prevention of occupational pathology at enterprises in the Arctic, special attention should be paid to achieving permissible levels of labor severity among workers engaged in mining operations.

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