scholarly journals Preliminary standardization of lashuna A potential drug for postmenopausal osteoporosis.

Author(s):  
Selva Kumari T. R. Thanga ◽  
S. Sujan ◽  
Janhavi Patharkar ◽  
Mansi Modi

Osteoporosis is a major international health problem, accentuated by increasing longevity. Osteoporosis as “a systemic skeletal disease characterized by low bone mass and bone architectural leading to increased risk”. Menopause is the normal process but now a day it becoming the major health problem in developing countries like India.   In Ayurveda Menopause deals with jarapakvaavasta of the body Jara and Rajonivritti are manifested due to the progressive reduction in the functional ability of Agnis, which results in an inadequate tissue nutrition. This nutritional imbalance triggers the irreversible degenerative changes in „Sapta Dhatus‟. The disease Osteoporosis is somewhat similar to the description of Asthi Kshaya in which metabolism of Asthi Dhatu is disturbed. Rasayana therapy has proved efficacious in managing and preventing many chronic conditions till date. As Postmenopausal Osteoporosis is a disease related to aging, Rasayana can provide the better alternative to increasing quality of life. Here, the drug Lashuna also one of the Rasayana guna dravya.  

2016 ◽  
Vol 1 (3) ◽  
Author(s):  
Jeffrey .

Early Childhood Caries (ECC) is a chronic disease that can be prevented. It commonlyaffects children involving in one or more decayed (with lesions or not) teeth, missing teeth (dueto caries), or teeth with fillings in children aged under 71 months. The disease is sometimesoverlooked, but this condition usually affects the general health of children. Early detection ofEarly Childhood Caries (ECC) can prevent problems which are harmful to children. Therefore,the ECC must be prevented and for teeth that have had dental caries they should be givenproper treatment so as not to worsen and affect the quality of life in children. Prevention of thisdisease is a significant component in any health program to prepare for the optimal basis forthe oral health of children. This condition will become a serious health problem if not handledproperly, and it is a major health problem for health providers throughout the world.Primarypreventive must be initiated since a woman getting pregnant.Keywords: Early Childhood Caries (ECC), prevention, treatment


2009 ◽  
Vol 2009 ◽  
pp. 1-2 ◽  
Author(s):  
Christian D. Becker ◽  
Robert A. Fischer

Acute cholecystitis is a major health problem. There are multiple etiologies to be considered and early recognition of the condition is important to optimize management and outcome. We report the first case in the medical literature of symptomatic acute cholecystitis triggered by ceftriaxone-associated gallbladder sludge formation and, importantly, solid ceftriaxone gallstone formation in an adult patient with underlying mineral and pigment cholecystolithiasis, necessitating cholecystectomy. This case serves as a reminder for physicians to keep this uncommon cause of cholecystolithiasis and cholecystitis in mind in patients who receive prolonged ceftriaxone therapy. These patients should be cautioned to promptly report to their physicians any signs or symptoms of cholecystitis in order to ensure timely and appropriate evaluation.


2012 ◽  
Vol 7 (1) ◽  
pp. 35-38
Author(s):  
Mohammad Salman ◽  
Syed Allahsan ◽  
Manzoor Mahmood ◽  
Md Khairul Anam ◽  
Shahed Mohammad Anwar ◽  
...  

Acute heart failure is a major health problem responsible for several million hospitalizations worldwide each year. Standard therapy has not changed for long time and includes diuretics and variable use of vasodilators or inotropes. Recently Nesiritide and Levosimendan are two drugs for the treatment of acute heart failure which have been approved by the Food and Drug Administration (FDA) and European Medicines Agency (EMEA), respectively. There was little concern that Nesiritide can worsen the renal failure but recent trials had abolished this concern. DOI: http://dx.doi.org/10.3329/uhj.v7i1.10208 UHJ 2011; 7(1): 35-38


2021 ◽  
Vol 11 (4) ◽  
pp. 102-105
Author(s):  
Lalita Sharma ◽  
Sudama Singh Yadav

Skin is the outermost covering of body and the largest organ of the integumentary system. Skin diseases are major health problem with emotional and psychological burden on patients. In Ayurvedic classics, almost all the skin diseases come under the broad heading of Kushtha. Dadru is a type of Kushtha which can be correlated with Tinea infection (fungal infection) in modern science. Three genera of dermatophytes infect skin i.e. Trichophyton spp, Epidermophyton spp and Microsporum spp. Ayurveda describes a multitude of treatment modalities for skin diseases in relation with various types of kushtha. One of them is the topical use of medicaments over the skin for topical absorption which allows faster absorption and better management of skin diseases. Lepa kalpana is a herbal or herbo-mineral drug for topical use. Although lepa is an important therapy in various diseases but it is highly useful specifically in dermatological diseases. This review describes different lepas which are especially mentioned for Dadru in doctrines of Ayurveda. Key words: Dadru, Kushtha, Lepa kalpana , Skin diseases.


Author(s):  
Swaha Satpathy ◽  
Arjun Patra ◽  
Bharti Ahirwar

AbstractPostmenopausal osteoporosis, a silent epidemic, has become a major health hazard, afflicting about 50% of postmenopausal women worldwide and is thought to be a disease with one of the highest incidences in senile people. It is a chronic, progressive condition associated with micro-architectural deterioration of bone tissue that results in low bone mass, decreased bone strength that predisposes to an increased risk of fracture. Women are more likely to develop osteoporosis than men due to reduction in estrogen during menopause which leads to decline in bone formation and increase in bone resorption activity. Estrogen is able to suppress the production of proinflammatory cytokines like interleukin (IL)-1, IL-6, IL-7 and tumor necrosis factor (TNF-α). This is why these cytokines are elevated in postmenopausal women. In this review article we have made an attempt to collate the various methods and parameters most frequently used for screening of antiosteoporotic activity in postmenopausal osteoporosis. Pertaining to ovariectomized animal model, this is the most appropriate model for studying the efficacy of different drugs to prevent bone loss in postmenopausal osteoporosis.


2020 ◽  
Vol 10 ◽  
Author(s):  
Abeer A. Bahnassy ◽  
Mona S. Abdellateif ◽  
Abdel-Rahman N. Zekri

Patients of African ancestry have the poorest outcome and the shortest survival rates from cancer globally. This could be attributed to many variables including racial, biological, socioeconomic and sociocultural factors (either single, multiple or combined), which may be responsible for this major health problem. We sought to assess the most common types of cancer that endanger the health of the African people, and tried to investigate the real differences between African and other Non-African patients regarding incidence, prevalence and mortality rates of different cancers. Therefore, identifying the underlying aetiological causes responsible for the increased incidence and mortality rates of African patients will allow for changing the current plans, to make optimized modalities for proper screening, diagnosis and treatment for those African patients, in order to improve their survival and outcomes.


2016 ◽  
Vol 35 (2) ◽  
pp. 192-194
Author(s):  
Nabanita Kora ◽  
Rajib Das ◽  
Sabyasachi Som ◽  
Sumanta Laha ◽  
Nayan Bannerji ◽  
...  

Correction: The correct PDF for this article was loaded on 9th March 2017. We offer our sincere apologies for having the wrong PDF loaded for this article.Stroke in child poses a major health problem. Thrombophilic factors have been implicated in 4-8% of young stroke worldwide. Protein S deficiency is a very rare cause of stroke. A few cases have been reported in literature. We are reporting a rare case of protein S deficiency causing stroke in a two year old child.J Nepal Paediatr Soc 2015;35(2):192-194


Nutrients ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 3852
Author(s):  
Vassilios Liakopoulos ◽  
Evangelia Dounousi

Chronic kidney disease (CKD) constitutes a major health problem worldwide [...]


1993 ◽  
Vol 21 (2) ◽  
pp. 151-155 ◽  
Author(s):  
A. M. Weeks ◽  
M. R. Buckland ◽  
E. B. Morgan ◽  
P. S. Myles

The Supervisors of Anaesthetic Training in Australia and New Zealand were surveyed and asked to report any cases of chemical dependence from anaesthetic registrars at their hospital from 1981 to 1991. From 83 questionnaires there were 65 (78%) returned. There were 14 departments (22%) with experience of one or more cases during this interval. Only five (7%) reported conducting a lecture or tutorial on the problem. The departmental reports covered 4425 registrar years of training and there were 17 cases reported. Of these, 13 were complete and are considered in detail. It is estimated that 1.3 % of those who entered anaesthetic training during the interval were recognised to become chemically dependent during their training. Follow-up was available on only six of the 13 registrars and only one was reported to have completed training. The results of this survey indicate that chemical dependence is already a major health problem amongst anaesthetic registrars in Australia and New Zealand.


RSC Advances ◽  
2018 ◽  
Vol 8 (41) ◽  
pp. 22866-22875
Author(s):  
Ming-jiao Li ◽  
Hong Xiao ◽  
Yi-xing Qiu ◽  
Jian-hua Huang ◽  
Rong-yong Man ◽  
...  

Cerebral infarction (CI) is one of the most common cerebrovascular diseases and remains a major health problem worldwide.


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