Study of the toxicological characteristics of plant extracts for use in sports nutrition products

2021 ◽  
pp. 74-79
Author(s):  
Юрий Георгиевич Симаков ◽  
Игорь Алексеевич Никитин ◽  
Сергей Александрович Иванов ◽  
Валерий Соломонович Штерман ◽  
Сергей Валерьевич Штерман ◽  
...  
Keyword(s):  
Danio Rerio ◽  
Molecular Level ◽  
Micronucleus Test ◽  
Classical Model ◽  
Sports Nutrition ◽  
Human Organism ◽  
Physical And Mental Health ◽  
Physiological Properties ◽  
The World ◽  
Positive Effect

В настоящее время имеются свидетельства, что ряд компонентов, образующихся в растениях, произрастающих в экстремальных условиях в ряде труднодоступных районов Южной Америки, Азии и Африки, в результате их успешного приспособления к особым условиям выживания, обладают уникальными физиологическими свойствами и способны оказывать мощное положительное воздействие на физическое и умственное здоровье людей. Вместе с этим точный состав этих растительных объектов и механизмы их воздействия на организм людей до настоящего времени изучены недостаточно. Это делает необходимым подробное исследование их токсикологических характеристик с целью получения экспериментальных доказательств возможности их безопасного применения в составе продуктов питания. Целью работы было изучение токсикологических характеристик новых перспективных компонентов спортивного питания - экстрактов маки перуанской, дамианы и L -теанина. Выявление биологической активности этих продуктов проводилось на классических модельных объектах, которые в настоящее время широко используются в подобных исследованиях во многих странах мира: на крови рыб данио ( Danio reriо ) и бактериях аэромонас ( Aeromonas gidrоphila ). Исследования, проведенные в направлениях выяснения влияния исследуемых продуктов на генотоксичность в эритроцитах рыб данио (микроядерный тест), на апоптоз (запрограммированную смену клеток) и эритропоэз (процесс кроветворения), показали, что ни один из исследованных препаратов не обладает генотоксичностью и не вызывает мутаций на молекулярном уровне. Было также обнаружено, что экстракты маки перуанской и дамианы подавляют рост условно патогенных бактерий человека, но не проявляют сильного токсического воздействия на микробиоту кишечника по сравнению со стандартным антибиотиком. Currently, there is evidence that a number of components formed in plants growing under extreme conditions in a number of hard-to-reach regions of South America, Asia and Africa, as a result of their successful adaptation to special conditions of survival, have unique physiological properties and are capable of exerting a powerful positive effect on physical and mental health of people. At the same time, the exact composition of these plant objects and the mechanisms of their effect on the human organism have not been sufficiently studied to date. This necessitates a detailed study of their toxicological characteristics in order to obtain experimental evidence of the possibility of their safe use in nutrition. The aim of the work was to study the toxicological characteristics of new promising components of sports nutrition - extracts of Maca Peruvian, Damiana and L -theanine. The investigation of the biological activity of these products was carried out on classical model objects, which are now widely used in similar studies in many countries of the world: on the blood of zebrafish ( Danio rerio ) and aeromonas bacteria ( Aeromonas gidrophila ). Studies carried out in the direction of elucidating the effect of the investigated products on genotoxicity in erythrocytes of zebrafish (micronucleus test), on apoptosis (programmed cell change) and erythropoiesis (hematopoiesis process) have shown that none of the investigated products has genotoxicity and does not cause mutations in molecular level. It was also found that extracts of Maca Peruvian and Damiana inhibit the growth of opportunistic human bacteria, but do not show a strong toxic effect on the intestinal microbiota compared to a standard antibiotic.

Consumption Emotions and Consumer Values among Turkish Consumers during the COVID-19 Pandemic

2020 ◽  
Vol 8 (2) ◽  
pp. 135-160
Author(s):  
Nevin Karabiyik Yerden
Keyword(s):  
Questionnaire Survey ◽  
Sampling Method ◽  
Significant Positive Effect ◽  
Consumption Emotions ◽  
The World ◽  
Consumer Values ◽  
Convenience Sampling ◽  
Business Structures ◽  
Consumer Lifestyles ◽  
Positive Effect

The COVID 19 pandemic created economic havoc around the world. Along with healthcare challenges, the pandemic has also been changing consumer lifestyles. It affects business structures and service delivery too. This article draws on an investigation of the effect of consumption emotions of Turkish consumers on consumer values during the COVID 19 Pandemic. A convenience sampling method was adopted in the study and a questionnaire survey was administered to collect 390 consumer cases. The results show that the consumption emotions of Turkish consumers during the COVID 19 Pandemichad a significant positive effect on consumer values. It was found that Turkish consumers were to feel anxiety, calmness and hope more often than not during the pandemic.

The relevance of dietetic approach of Ayurveda from the perspective of COVID-19 pandemic

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 748-752
Author(s):  
Swapnali Khabade ◽  
Bharat Rathi ◽  
Renu Rathi
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Healthy Person ◽  
World Health ◽  
Physical And Mental Health ◽  
Leading Role ◽  
Global Pandemic ◽  
The People ◽  
The World ◽  
Health Organization ◽  
The Individual

A novel, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causes severe acute respiratory syndrome and spread globally from Wuhan, China. In March 2020 the World Health Organization declared the SARS-Cov-2 virus as a COVID- 19, a global pandemic. This pandemic happened to be followed by some restrictions, and specially lockdown playing the leading role for the people to get disassociated with their personal and social schedules. And now the food is the most necessary thing to take care of. It seems the new challenge for the individual is self-isolation to maintain themselves on the health basis and fight against the pandemic situation by boosting their immunity. Food organised by proper diet may maintain the physical and mental health of the individual. Ayurveda aims to promote and preserve the health, strength and the longevity of the healthy person and to cure the disease by properly channelling with and without Ahara. In Ayurveda, diet (Ahara) is considered as one of the critical pillars of life, and Langhana plays an important role too. This article will review the relevance of dietetic approach described in Ayurveda with and without food (Asthavidhi visheshaytana & Lanhgan) during COVID-19 like a pandemic.

USE OF ESSENTIAL FATTY ACIDS AND THEIR ROLE IN THE HUMAN ORGANISM DEVELOPMENT

2018 ◽  
Vol 28 (4) ◽  
pp. 1219-1225
Author(s):  
Filip Jovanovski ◽  
Toni Mitrovski ◽  
Viktorija Bezhovska
Keyword(s):  
Fatty Acids ◽  
Unsaturated Fatty Acids ◽  
Essential Fatty Acids ◽  
Normal Growth ◽  
The Body ◽  
Human Nutrition ◽  
Human Organism ◽  
Working Ability ◽  
The World ◽  
Growth Development

Food is not just a pleasure in life, it is also an important factor for our health. Human nutrition is a mixture of nutrients, which are the only source of energy needed for survival. Energy-poor diet endangers many life functions, and above all the working ability. In the world, the meaning of the diet is very serious, and hence the demands for a –rational, healthy and safe diet are growing. Human nutrition contains saturated and unsaturated fatty acids. Essential fatty acids (EFAs) must be ingested in everyday diet because the body does not produce it. They are very important for human health. They are present in each cell of the human body and are an important factor for the normal growth, development and functioning of cells, muscles, nerves and organs. They are also used in the production of certain hormones - such as prostaglandins, which are crucial for the performance of certain important processes. The deficit from EFAs is due to a number of health problems, including more serious diseases.

Internet Pornography Addiction and Effects of Excessive Pornography Consumption: A University Tunku Abdul Rahman Undergraduate Student Study

2015 ◽  
Vol 1 ◽  
Author(s):  
Ahsha Vaksalla
Keyword(s):  
Female Students ◽  
The Internet ◽  
Negative Dimension ◽  
Internet Pornography ◽  
Pornography Consumption ◽  
The World ◽  
Research Population ◽  
Negative Effect ◽  
Pornography Addiction ◽  
Positive Effect

Pornography is a debatable subject, both in Malaysia and around the world. Some feel it is harmless while others feel it is damaging. Pornography can bring about its own impact to the viewers. In Malaysia, the trend of viewing pornography among youngsters’ has been increasing. Studies have also shown Pornography can lead to unhealthy behaviors as a result of too much viewing. This study was conducted to discover the addiction level and the consumption effects on students at a Malaysian University. The researchers used purposive sampling to distribute questionnaires. The Scale used was the Internet Pornography Addiction Test and the Pornography Consumption Effects Scale consist of Positive and Negative dimension used to conduct the research. The research population (N=120) was students’ from University Tunku Abdul Rahman of Malaysia. There were significant relationship between the addiction and consumption. There were significant differences between the Positive and Negative Dimension as well. The Negative Effect Dimension is higher than the Positive Effect Dimension. There were significant differences between male and female students towards pornography addiction. However, there were not any significant differences among the genders in internet consumption. Male scored higher than female in the Internet Pornography Addiction. There were no significant differences between gender in the Positive and Negative Dimension.

Immunomodulatory Effect of “Dr. M.S. Reddy’s Multiple Mixed Strain Probiotic Therapy” to Cure or Prevent Hospital Acquired (Nosocomial) Infections due to Clostridium difficile (C. diff), other Pathogenic Bacteria, and Autoimmune Diseases

2018 ◽  
Vol 11 (1) ◽  
pp. 3937-3949
Author(s):  
Malireddy S Reddy
Keyword(s):  
Immune System ◽  
Gastrointestinal Tract ◽  
Pathogenic Bacteria ◽  
Molecular Level ◽  
Host Immune System ◽  
Hospital Acquired Infections ◽  
The World ◽  
Probiotic Strains ◽  
The Individual ◽  
Hospital Acquired

The worldwide popularity of Dr. M.S. Reddy’s Multiple Mixed Strain Probiotic Therapy to treat or prevent the hospital acquired infections (nosocomial infections) arose a great interest in the medical community around the world (Reddy and Reddy, 2016; 2017). The following questions were raised on this subject: Does Multiple Mixed Strain Probiotics directly inhibit the pathogenic bacteria (C. diff) in the gastrointestinal tract or indirectly through modulation of the host immune system or both? To be more specific, what is the exact and/or hypothetical mechanism at molecular level behind the breakthrough discovery of Dr. M.S. Reddy’s Multiple Mixed Strain Probiotic Therapy?  To answer these questions, the specific immunomodulation regulatory functions of the individual Probiotic strains (on host) have beenresearched, investigated andoutlined in this article.  A detailed explanation(s) and hypotheses have been proposed outlining the possible cumulativedirect bacteriological and indirect immunomodulatory effects (at the molecular level) of the Multiple Mixed Strain Probiotics used in Dr. M.S. Reddy’s Multiple Mixed Strain Probiotic Therapy to successfully treat C. diff infection.  A detailed scientific and research attempts were made to correlate the Probiotic induced immune activities in relation to the reduction of the symptoms associated with the hospital acquired Clostridium difficile infection during and after the Multiple Mixed Strain Probioitc Therapy.  Results of the clinical trials, microbiological tests on feces, and the clinical blood tests significantly revealed that the reasons for the success of Dr. Reddy’s Multiple Mixed Strain Probiotic Therapy are multifold. Presumably, it is predominantly due to the immunomodulatory effect they have exerted on the host immune system along with the direct inhibition of C. diff bacteria by multiple Probiotics, due to the production of bacteriocins, lactic acid and nutritional competency.In addition, the size of the individual cells of the Probiotic strains in the Multiple Mixed Strain Probiotics and their significant effect on immunomodulation has been thoroughly discussed. Results clearly proved that if Probiotics are absent in the GI tract during C. diff infection, the chances of patient survival is zero.  This is because of the excess immune stimulation and incurable damage to the epithelial cell barrier of the gastrointestinal tract caused by C. diff bacteria.  The results also revealed, without any doubt, as of to-datethe latest discovery of Dr. M.S. Reddy’s Multiple Mixed Strain Probiotic Therapy is the best way to cure the deadly hospital acquired infections affecting millions of people around the world, with high degree of mortality.  This has been attested by several practicng medical professionals and scientists around the world (Reddy and Reddy, 2017).

Über Normalität und Abweichung: Ein responsiver Ansatz

2020 ◽  
Vol 68 (1) ◽  
pp. 79-100
Author(s):  
Michela Summa
Keyword(s):  
Human Organism ◽  
The World

AbstractThis article aims to highlight the relevance of Bernhard Waldenfels’ responsive phenomenology for questions related to normality and to the different kinds of deviation from what is taken tobe normal. The article begins with a discussion of two limit cases in the understanding of the concepts of normality and deviation: a strictly normative understanding, according to which each deviation is norm-deviation, and a descriptive understanding, according to which deviation is what underlies individuality. Considering Waldenfels’ responsive philosophy in connection with Kurt Goldstein’s and George Canguilhem’s philosophies of the organism, both understandings are critically discussed. In particular, the article shows how both views turn out to be one-sided and should be revised on the basis of a responsive account of the organism (particularly of the human organism) and its situated relation to circumstances, events, and affordances in the world it inhabits. The analysis of the different forms of responsiveness of the human organism, and notably the distinction between ‘catastrophic’ or pathological and ‘creative’ or organising kinds of responsiveness, can allow us to develop a relational and dynamic account of normality and deviation. Accordingly, neither normality nor deviation should be taken as univocally defined states; they should rather be reassessed on the basis of the processes in and through which order is interrupted, disturbed, and possibly reshaped or newly instituted.

Do Development and Democracy Positively Affect Gender Equality in Cabinets?

2015 ◽  
Vol 16 (3) ◽  
pp. 332-356 ◽  
Author(s):  
JOHN HÖGSTRÖM
Keyword(s):  
Economic Development ◽  
Gender Equality ◽  
Empirical Evidence ◽  
Comparative Studies ◽  
Developed Countries ◽  
Political Regimes ◽  
The World ◽  
Different Types ◽  
Negative Effect ◽  
Positive Effect

AbstractIt has been argued that economic development and democracy create new opportunities and resources for women to access political power, which should increase gender equality in politics. However, empirical evidence from previous research that supports this argument is mixed. The contribution of this study is to expand the research on gender equality in politics through an in-depth examination of the effect of development and democracy on gender equality in cabinets. This has been completed through separate analyses that include most of the countries in the world across three levels of development (least-developed, developing, and developed) and across different types of political regimes (democracies, royal dictatorships, military dictatorships, and civilian dictatorships). The results demonstrate that economic development and democracy only affect gender equality in cabinets positively in a few environments. Accordingly, the context is important and there seem to be thresholds before development and democracy have any effect. Development has a positive effect in developed countries and in democracies, but it has a negative effect in dictatorships, and the negative effect is strongest in military dictatorships. The level of democracy has a positive effect mainly in dictatorships, and the strongest effect is in civilian dictatorships. The article demonstrates the importance of dividing samples into subsets to increase understanding of what affects women's representation in cabinets in different environments, and I ask scholars to subset samples and run separate analyses more often in comparative studies.

The Association Between Racism and Suicidality Among Young Minority Groups: A Systematic Review

2021 ◽  
pp. 104365962110469
Author(s):  
Giorgia Rudes ◽  
Claudia Fantuzzi
Keyword(s):  
Systematic Review ◽  
Health Care Professionals ◽  
Suicide Risk ◽  
Minority Groups ◽  
World Health ◽  
Physical And Mental Health ◽  
Dominant Culture ◽  
The World ◽  
Health Organization ◽  
The Relationship

Introduction: The World Health Organization states that suicide is the second leading cause of death among youngs, and racism has been proven to have detrimental effects on both physical and mental health. These two plagues represent a public health priority, especially for susceptible minorities. Method: This systematic review analyzed 23 studies from multiple database searches, to understand the relationship between racism and suicidality in young minority groups. Results: The review demonstrated the correlation between racism and suicidality with the consequent development of mental disorders. There is strong evidence that the main suicide risk factor is acculturation, interpreted as the assimilation of the dominant culture with the loss of values from one’s cultural background. Discussion: Health care professionals should not underestimate the risk of suicidality associated with racism. Prevention is crucial and it should be implemented from a young age, in schools, through a joint intervention with children and their families, aiming toward integration without acculturation.

scholarly journals Universal Maternal Rights: A Matter of Life and Death

2021 ◽  
Author(s):  
Alicia Ryan
Keyword(s):  
Developing Countries ◽  
Maternal Mortality ◽  
Obstetric Care ◽  
Maternal Deaths ◽  
Scientific Methods ◽  
Life And Death ◽  
The World ◽  
Positive Effect ◽  
Multiple Obstacles ◽  
Maternal Rights

Childbirth has been a part of our lives since the beginning of time. Without the process none of us would be alive today. So why is it that maternal mortality remains one of the greatest inequities in the world? To date, approximately 500, 000 women die annually due to the lack of appropriate prenatal and obstetric care. Difficulties arising with childbirth cannot be predicted. However, the way in which we react to a situation can have a lasting, positive effect on the countries and the women who are at risk. The ways in which to help reduce the large number of maternal deaths in developing countries is not complicated and can be achieved if it is made a priority. In conclusion, there are multiple obstacles in regard to succeeding the highest achievable standard of health globally.  With the education of evolving scientific methods, and the collaboration of humanitarian views, the welfare and health of women and their children, can be internationally restored. With the education of evolving scientific methods, and the collaboration of humanitarian views, the welfare and health of women and their children, can be internationally restored.

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