scholarly journals Proximate and Sensory Analysis of Functional Drink from Jackfruit Seed Extract with Citrulline Fortification As A Potential Antidiabetic

2021 ◽  
Vol 1 (2) ◽  
pp. 56-64
Author(s):  
William Ben Gunawan ◽  
Amelia Septyn Priambodo ◽  
Diah Winarti ◽  
Aprilia Nurohma ◽  
Laurencia Okky Wijayanti
Keyword(s):  
Diabetes Mellitus ◽  
Blood Sugar ◽  
Sensory Analysis ◽  
Proximate Analysis ◽  
World Health ◽  
Antioxidant Content ◽  
Sugar Levels ◽  
Health Organization ◽  
Functional Drink ◽  
Peel Extract

The World Health Organization (WHO) predicts that diabetes Mellitus in Indonesia by 2030 will increase to 21.3 million people. There was a growing need for natural foods that can be used as a substitute for antihyperglycemic drugs and may lower the blood sugar levels of diabetes Mellitus patients without burdening the kidneys and causing other side effects. Citrulline, one of the amino acids that are useful for the immune system and improving blood flow circulation, is found in the white peel of watermelon in greater levels compared to the citrulline content of other fruits. Previous research has shown that citrulline supplementation significantly lowered fasting blood sugar and HbA1c as well as inflammatory biomarkers, including in obese subjects. Methods conducted in this study include watermelon peel extract making, jackfruit seed drink making, proximate analysis, total phenol testing, organoleptic testing, and data analysis. The results of proximate testing on jackfruit seed drink with additional citrulline (F1) were F1 samples consisting of 92.31% water, 0.47% protein, 0.99% fat, 0.00% ash, and 6.23% total carbohydrates. Sensory analysis revealed that the flavor of the drink was disliked, while the aroma of the drink was somewhat liked. The addition of watermelon peel extract in jackfruit seed drinks may increase nutrition value, antioxidant content, and has the potential to be a functional drink with antioxidant content and blood sugar reduction effects as antidiabetics.

scholarly journals Pelatihan Teknik Suntik Insulin Pada Keluarga Penderita Diabetes Mellitus Di Dusun Pattiro Desa Paccelekang Kec.Pattalassang Kab.Gowa

2021 ◽  
Vol 4 (5) ◽  
pp. 1109-1116
Author(s):  
Sriwahyuni Sriwahyuni ◽  
Sri Darmawan
Keyword(s):  
Diabetes Mellitus ◽  
Health Education ◽  
World Health Organization ◽  
Health Workers ◽  
Insulin Injection ◽  
World Health ◽  
Injection Technique ◽  
Sugar Levels ◽  
Health Organization ◽  
The Right

ABSTRAK Penyakit Diabetes merupakan salah satu penyakit degeneratif yang terkait langsung dengan gaya hidup atau life style, Menurut World Health Organization (WHO), pada tahun 2014, 8,5% dari orang dewasa berusia 18 tahun dan lebih tua menderita diabetes. Indonesia berdasarkan wawancara yang terdiagnosis dokter sebesar 1,5%, dan Provinsi Sulawesi Selatan pada tahun 2014, jumlah Kasus Diabetes Mellitus (282 penderita) terdiri atas Diabetes mellitus yang terlapor (207 penderita), Diabetes mellitus yang tidak terlapor (160 penderita) dan Diabetes mellitus bergantung insulin (72 penderita) Peran dari tenaga kesehatan dan orang terdekat yang sangat dianggap penting oleh penderita juga sangat mempengaruhi perilaku dalam mengontrol kadar gula darah penderita DM Tipe II, karena jika tidak ada dukungan dan motivasi dan health edukasi dari tenaga kesehatan  serta orang terdekat maka penderita cenderung tidak memperhatikan status kesehatannya. Kegiatan ini sasaran utama adalah keluarga penderita Diabetes Mellitus yang aktif melakukan suntik insulin yang ada di Dusun Pattiro Desa Paccelekang Kec.Pattalassang Kab.Gowa . Salah satu cara yang ditempuh sebelum dilakukan pelatihan adalah dengan melakukan pertemuan dan pendataan terlebih dahulu tentang warga yang memiliki riwayat aktif melakukan suntik insulin. Pelatihan teknik dan keterampilan melakukan suntik insulin yang tepat Daya serap para peserta terhadap materi kegiatan cukup baik, hal ini terlihat dari kemampuan masyarakat menjawab dan mempraktikan Teknik Suntik Insulin..Kata kunci : Health Edukasi, Pelatihan, Suntik Insulin, Diabetes Mellitus  ABSTRACT Diabetes is a degenerative disease that is directly related to lifestyle, according to the World Health Organization (WHO), in 2014, 8.5% of adults aged 18 years and older suffered from diabetes. Indonesia based on interviews with diagnosed doctors by 1.5%, and South Sulawesi Province in 2014, the number of Diabetes Mellitus Cases (282 patients) consisted of reported Diabetes Mellitus (207 cases), Unreported Diabetes Mellitus (160 cases), and Diabetes Insulin-dependent Mellitus (72 patients) The role of health workers and loved ones who are very important to sufferers also greatly affects behavior in controlling blood sugar levels for people with Type II diabetes, because if there is no support and motivation and health education from health workers and those closest to them then sufferers tend not to pay attention to their health status. This activity is the main target for families with Diabetes Mellitus who actively inject insulin in the Pattiro Hamlet, Paccelekang Village, Pattalassang District, Gowa Regency. One of the methods taken before training is to conduct meetings and collect data in advance about residents who have a history of actively injecting insulin. Training on techniques and skills for performing the right insulin injection The participants' absorption of the activity material was quite good, this can be seen from the community's ability to answer and practice the Insulin Injection Technique. Keywords: Health Education, Training, Insulin Injection, Diabetes                   Mellitus

scholarly journals Anti-malaria and hypoglycaemic activities of Diosgenin on alloxan-induced, diabetic Wistar rats

2021 ◽  
Vol 15 (3) ◽  
pp. 073-079
Author(s):  
Omoirri Moses Aziakpono ◽  
Madubogwu Ngozi Ukamaka ◽  
Oraekei Daniel Ikechukwu ◽  
Ataihire Johnson Uyovwiesevwa ◽  
Chukwuemeka Charles Ofili ◽  
...  
Keyword(s):  
Body Weight ◽  
Blood Sugar ◽  
Wistar Rats ◽  
World Health ◽  
Treatment Groups ◽  
Male Wistar Rats ◽  
Normal Rat ◽  
Sugar Levels ◽  
Health Organization ◽  
Alloxan Monohydrate

The rising threat of Plasmodium falciparum resistance to Monotherapies has prompted the world health organization (WHO) 2006 guidelines to recommend the use of different anti-malarias. In this study, the anti-malaria and hypoglycaemic activities of Diosgenin, a potent, yet poorly reported saponin was investigated on P. falciparum inoculated and Alloxan-Induced, Diabetic Wistar Rats. Fort two (42) adult male wistar rats of between 100g and 150g were procured, acclimatized (for two weeks), and grouped into seven of six (6) rats per group. While Group 1 (Normal control) received normal rat chow and water ad libitum, groups 2 – 4 received no treatment (untreated), 10 mg/kg body weight of anti-diabetic Metformin and 25 mg/kg body weight of diosgenin respectively after inducing diabetes mellitus (DM) with alloxan monohydrate; whereas, groups 5-7 (all malaria infected) were untreated (negative malaria control), 25 mg/kg body weight of diosgenin and 56 mg/kg body weight of anti-malaria coartem respectively. Following treatment period, blood samples were obtained and assayed for fasting blood sugar, packed cell volume (PCV) and total white blood cell count (TWBCC). From the result, P. falciparum exposed rats showed lowered PCV values than control with observed improvements in coartem (significant at p < 0.05) and diosgenin (insignificant) treatment groups. Also, diabetic, diosgenin treated rats showed an insignificant reduction in blood sugar levels compared to control, even though this change was apparently improved compared to diabetic, untreated group. Again, TWBCC caused notable decrease in diosgenin treated, though this decrease signified a huge recovery compared to untreated rats. Corroborative studies on diosgenin with other systems is recommended.

scholarly journals WORLD HEALTH DAY–DIABETES, A GROWING MENACE

2016 ◽  
Vol 2 (2) ◽  
pp. 1
Author(s):  
Sofia Shehzad
Keyword(s):  
Diabetes Mellitus ◽  
Blood Sugar ◽  
Insulin Dependent Diabetes Mellitus ◽  
Insulin Dependent Diabetes ◽  
World Health ◽  
Dependent Diabetes Mellitus ◽  
Type I ◽  
Type Ii ◽  
Insulin Dependent ◽  
Sugar Levels

World Health day, celebrated each year on 7th of April is all about creating awareness regarding health issues confronting the global population. The theme this year is Diabetes — a metabolic disorder of menacing proportion. There are a host of misconceptions and lack of understanding amongst the general public regards its exact etiology, prevention, control and socio-economic impact. As of 2015 the prevalence of the disease worldwide is estimated around 415 million affectees1. This number is expected to rise to 592 million by 2035 2. The incidence and resultant mortality secondary to this epidemic is on the rise in low and middle economy countries such as Pakistan, with the disease expected to be the 7th leading cause of death by 2030 3 . Diabetes occurs when the pancreas loses its ability to produce the required insulin or the body fails to utilize the later resulting in raised blood sugar levels 4. As a consequence, malfunctioning of various organ systems ensues and various life threatening illnesses including heart attacks, strokes, nerve damage, kidney failure, blindness, impotence and infections takes a toll on the patient's health. Broadly it is classified into 3 types - Type I or Insulin dependent diabetes mellitus also referred to as 'juvenile diabetes' in which the production of insulin is affected - Type II or Non insulin dependent diabetes mellitus characterized by insulin resistance, and having a strong correlation with increased body weight and lack of exercise 5. It is also called `adult onset 'diabetes'. - Gestational diabetes affecting pregnant women with no past history of the disease, usually in the 2Ild or 3rd trimester 6. The disease usually manifests with the symptoms of frequent urination, thirst and hunger. Once a diagnosis is made based on Blood sugar estimation and monitoring levels of glaciated hemoglobin - HbAl c, management ensues directed at achieving optimum level of blood glucose and avoiding systemic complications. This goal is achieved by introducing life style changes from a sedentary to more active and less stressful way of living, supplemented with a balanced diet and regular exercise. This is especially helpful in Type II DM. Treatment is offered by means of Oral hypoglycemic or injectable insulin as guided by the physician/endocrinologist. More recently bariatric Surgery has shown considerable promise as an effective measure to control blood sugar levels.7 This year the main objective of observing the world health day is to enhance awareness about prevention, care and surveillance of this disease. This will form the basis for launching the first ever global report on Diabetes. The core functions of WHO in this regard are as follows: - To frame internationally acceptable standards and guidelines for prevention, diagnosis and treatment of Diabetes and its associated complications - To closely monitor the morbidity and mortality associate with this disease. - Capacity building at different levels to address different aspects of this disease - To project diabetes as a global health issue and identify the population at risk Efforts to prevent and treat diabetes are essential to achieve the global sustainable development goal target of reducing premature mortality from non communicable diseases by one third by 2030. The community at large and the health care professionals and organizations in particular have a key role to play in highlighting the steps to be taken in this regard through organizing seminars and lectures and making use of the media to effectively communicate their  message to the masses.Globalhealth dayfocusing onDiabetes certainlypromises tobe akeyeventin raising awareness andproposing effective measures supplementing themanagement of this disease ona globalstage.

Endocrine and Therapeutic Basis of Diabetes Mellitus Therapy

2019 ◽  
Vol 12 (2) ◽  
pp. 4441-4452
Author(s):  
Mayank Kulshreshtha ◽  
Pragati Srivastava ◽  
Dharamveer Panjwani
Keyword(s):  
Diabetes Mellitus ◽  
Microvascular Complications ◽  
Developed Countries ◽  
Scientific Data ◽  
World Health ◽  
Middle Income ◽  
Middle Income Countries ◽  
Daily Exercise ◽  
Sugar Levels ◽  
Health Organization

This review article describes the role of hormones, microvascular complications, pharmacological and non-pharmacological treatments and precautions of diabetes therapy. Diabetes mellitus (DM) is a chronic, lifelong condition that affects ability to use the energy found in food. According to World Health Organization (WHO), it is estimated 422 million adults are suffered with DM up to latest 2016 data.  It occurs throughout the world but is more common in the more developed countries. Increase in prevalence is occurring in low- and middle-income countries including in Asia and Africa, where most patients will probably be found by 2030. The WHO estimates that diabetes resulted in 1.5 million deaths in 2012, making it the 8th leading cause of death. We summarized the published scientific data and new development in the field of diabetes with a search of PubMed, Google scholar, med know and other online resources.  Various hormones play an important role in which insulin has a more importance in DM. Pharmacological treatment included various side effects while herbal drugs are found to be safe. Diet and exercise are the excellent key points to cure the disease. Avoid high sugar diet and various foods whose sugar levels are high should be avoided at the age 40.  Overall, better knowledge, balanced life style, and daily exercise are the excellent treatment of diabetes and effective glucose control.   

scholarly journals Comparative Evaluation of the Nutritive, Mineral, and Antinutritive Composition of Musa sinensis L. (Banana) and Musa paradisiaca L. (Plantain) Fruit Compartments

Plants ◽  
2019 ◽  
Vol 8 (12) ◽  
pp. 598 ◽  
Author(s):  
Barnabas Oluwatomide Oyeyinka ◽  
Anthony Jide Afolayan
Keyword(s):  
Inductively Coupled Plasma ◽  
Therapeutic Potential ◽  
Optical Emission ◽  
Proximate Analysis ◽  
World Health ◽  
Tropical Regions ◽  
Inductively Coupled ◽  
Musa Paradisiaca ◽  
Health Organization ◽  
Peel Extract

Banana and plantain contribute significantly to food security and amelioration of malnutrition, earning their status as staples in several localities of tropical and sub-tropical regions. The distribution of metabolites within the various parts also remains as a key essential to their nutritive and therapeutic potential. This study was aimed at evaluating the nutritional and mineral composition of the flesh, peel, and peel extract components of Musa sinensis L. and Musa paradisiaca L. fruits as well as their nutritional and therapeutic potentials. Proximate and antinutritional analyses were carried out using standard analytical methods of the Association of Official Analytical Chemists (AOAC), while the mineral constituents were evaluated using inductively coupled plasma optical emission spectroscopy (ICP-OES). Proximate analysis revealed that the flesh and peel of M. sinensis L. and M. paradisiaca L. contain substantial amounts of moisture, fiber, carbohydrates, and low fat content, while minerals K, Mg, Ca, Na, P, and N were substantially concentrated in the peels and peel extracts in particular. The antinutrients alkaloid, oxalate, saponin, and phytate were detected in safe amounts according to the World Health Organization (WHO). The study points out that the peel and its derivative extract, as well as the flesh of M. sinensis L. and M. paradisiaca L. are to be put to more relevant human nutritional and therapeutic use.

scholarly journals HUBUNGAN USIA, JENIS KELAMIN DAN INDEKS MASSA TUBUH DENGAN KADAR GULA DARAH PUASA PADA PASIEN DIABETES MELITUS TIPE 2 DI KLINIK PRATAMA RAWAT JALAN PROKLAMASI, DEPOK, JAWA BARAT

2020 ◽  
pp. 41-50
Author(s):  
K Komariah ◽  
Sri Rahayu
Keyword(s):  
Diabetes Mellitus ◽  
Blood Sugar ◽  
Cross Sectional Study ◽  
Fasting Blood Sugar ◽  
World Health ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Sugar Levels ◽  
Diabetes Melitus

Diabetes melitus biasa disebut “the silent killer” karena penyakit ini dapat menimbulkan dampak pada semua organ tubuh dan berbagai macam keluhan. Data World Health Organization (WHO) memprediksi kenaikan jumlah pasien diabetes melitus di Indonesia dari 8,43 juta jiwa pada tahun 2000 menjadi 21,257 juta jiwa pada tahun 2030. Peningkatan kejadian kasus diabetes melitus dipengaruhi berbagai faktor seperti perubahan pola gaya hidup, perubahan usia, dan kultur. Penelitian ini bertujuan untuk mengetahui hubungan usia, jenis kelamin dan indeks massa tubuh dengan kadar gula darah puasa pada pasien diabetes melitus tipe 2. Metode penelitian ini menggunakan desain penelitian cross-sectional study. Penelitian ini dilakukan di Klinik Pratama Rawat Jalan Proklamasi, Depok, Jawa Barat dengan jumlah sampel sebanyak 134 responden. Pengambilan sampel pada penelitian ini menggunakan metode purposive sampling. Analisa data menggunakan uji Chi Square. Hasil penelitian menunjukkan bahwa yang berhubungan dengan kadar gula darah puasa adalah usia (p-value=0,004). Pada variabel yang tidak memiliki hubungan dengan kadar gula darah puasa adalah jenis kelamin (p-value=0,331), dan dan indeks massa tubuh (p-value=0,502). Jadi, dapat disimpulkan bahwa usia perlu diperhatikan dalam melakukan perawatan diabetes melitus tipe 2.   Diabetes mellitus is commonly called “the silent killer” because this disease can have an impact on all organs of the body and various complaints. The World Health Organization (WHO) predicts an increase in the number of diabetes mellitus patients in Indonesia from 8.43 million in 2000 to 21.257 million in 2030. Increased incidence of diabetes mellitus cases is influenced by various factors such as changes in lifestyle patterns, age changes, and culture. This study aimed to determine the relationship of age, sex and body mass index with fasting blood sugar levels in patients with type 2 diabetes mellitus. The method of this study used a cross-sectional study design. This research was conducted at the Klinik Pratama Rawat Jalan Proklamasi, Depok, West Java with a total sample of 134 respondents. Sampling in this study used a purposive sampling method. Data analysis using the Chi-Square test. The results showed that age-related blood fasting blood sugar levels (p-value=0,004). The variables that have no relationship with fasting blood sugar levels are gender (p-value=0,331) and body mass index (p-value=0,502). It can be concluded that age has to be considered in treating type 2 diabetes mellitus.

scholarly journals Diabetes Mellitus and Its Associated Risk Factors among adult Population in Bisha Province, Southwest of Saudi Arabia

2016 ◽  
Vol 9 (6) ◽  
pp. 22 ◽  
Author(s):  
Abdullah M. Al-Shahrani ◽  
Mohammed A. Al-Saleem ◽  
Mohamed O’haj ◽  
Faleh Th. Mohammed ◽  
Mutasim E. Ibrahim
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Healthy Lifestyle ◽  
Adult Population ◽  
Cross Sectional Study ◽  
World Health ◽  
Cross Sectional ◽  
Married Individuals ◽  
Health Organization ◽  
Associated Risk Factors

OBJECTIVES: To determine the prevalence and associated risk factors of diabetes mellitus (DM) among the adult population in Bisha province, Saudi Arabia.METHODS: A cross sectional study was conducted during December, 2015 using the World Health Organization STEPS wise approach for data collection. Blood glucose level and anthropometric measurements of blood pressure, height, weight, and waist circumference were performed per standard methods.  Logistic regression analysis was used to assess the prevalence and risk of diabetes.RESULTS: Of 542 adult individuals included in the study, 13.3% (72) had diabetes, of which 8.1% were previously diagnosed and 5.2% represented new cases. The proportions of DM were 14.7% for men and 10.8% for women. Diabetes was significantly higher among married compared to unmarried individuals (19.3% vs 5.5 %; p<0.001) and among individuals aged ≥40 years old compared to those <40 years (31.3% vs 9.3%; p<0.001). The risk of diabetes was significantly increased with older age (Odds Ratio=4.470; 95% CI 2.264-7.614), married individuals (OR=4.097; 95% CI 2.188-7.672), weight/obesity (OR=2.827; 95% CI 1.567-5.072), hypertension (OR=4.383; 95% CI 2.085-9.214) and having a job (OR=2.327; 95% CI 1.347-4.02). The independent risk factors predicted diabetes were hypertension (Adjusted OR=2.897; 95% CI 1.269-66.13) and job patterns (Adjusted OR=2.793; 95% CI 1.064-7.329).CONCLUSION: Different risk factors alarming diabetes among adult population in Bisha province were detected.  Strategies aimed to improving a healthy lifestyle are necessary to reduce the burden of the disease. 

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