Risk Factors for Prolonged Utilization of Nasal Decongestants in Students of Biomedical Sciences

2021 ◽  
Vol 9 (1) ◽  
pp. 30
Author(s):  
Aleksandra Dugalic ◽  
Nikola Davidoski ◽  
Slobodan Jankovic
Author(s):  
Pierre M. Tebeu ◽  
Aurelien Kamdem ◽  
Jean P. Ngou-Mve-Ngou ◽  
Esther Meka ◽  
Jesse S. S. Antaon ◽  
...  

Background: Surgical site infection is the invasion by microorganisms of the tissue layers affected by the surgical procedure. Maternal morbidity from infections has been shown to be higher after caesarean section compared to the vaginal delivery. Objective of the research was to analyze the risk factors associated with surgical site infections after caesarean section.Methods: This was a cross sectional (affected/non affected) study approved by the institutional committee for ethics and research of the faculty of medicine and biomedical sciences. A total of 310 medical files were assessed, 62 files from patients with surgical site infections and 248 files from patients without any complications. The data was collected using a pretested questionnaire and analyzed using the statistical package for the social sciences (SPSS) software version 22.0. The Chi squared and the Fisher exact tests were used to assess homogeneity between the 2 groups. Odd ratio 95% confidence interval was used to assess the association between the variables.Results: The proportion of surgical site infections during the study was 1.81%. Factors associated with surgical site infections were premature rupture of membranes (OR: 2.065; 95% CI 1.051-4.05; p=0.035); the vertical midline incision (OR=5.26; 95% CI; 1.41-19.57; p=0.013) and a operation by a resident physician doctor (OR=1.98; 95% CI 1.09-3.59; p=0.02).Conclusions: A factors associated with surgical site infections after caesarean section are a premature rupture of membranes, vertical midline incision and the qualification of the practitioner.


Author(s):  
Kenneth F. Schaffner

In this chapter I shall examine the relations between what appear to be two somewhat different concepts of causation that are widely employed in the biomedical sciences. The first type is what I term epidemiological causation. It is characteristically statistical and uses expressions like "increased risk" and "risk factor." The second concept is more like the form of causation we find in both the physical sciences and everyday life, as in expressions such as "the increase in temperature caused the mercury in the thermometer to expand" or "the sonic boom caused my window to break." In the physical and the biological sciences, such claims are typically further analyzed and explained in terms of underlying mechanisms. For example, accounts in the medical literature of cardiovascular diseases associated with the ischemic myocardium typically distinguish between the risk factors and the mechanisms for these disorders (Willerson 1982). Interestingly, both concepts of causation have found their way into the legal arena, the first or epidemiological concept only relatively recently in both case law and federal agency regulatory restrictions. The second, perhaps more typical, notion of causation has turned out to be not so simple on deeper analysis and led Hart and Honoré, among others, to subject the notion to extensive study in their classic book Causation in the Law. In another paper (Schaffner 1987), I examined some of these issues, in particular the epidemiological concept of causation as it might apply to recent DES cases such as Sinddl and Collins. Reflections on the Sindell case and on one of its legal precedents, the Summers v. Tice case, led Judith Jarvis Thomson to introduce a distinction between two types of evidence that might be adduced to support a claim that an agent caused harm to a person. The two types of evidence parallel the distinction between these two concepts of causation, and 1 shall introduce them by means of a particularly striking example originally credited to David Kaye (Kaye 1982).


2017 ◽  
Vol 5 (3) ◽  
pp. 45-55
Author(s):  
Y. Obirikorang ◽  
C. Obirikorang ◽  
O.A. Enoch ◽  
E. Acheampong ◽  
P. Tuboseiyefah ◽  
...  

Prevalence and risk factors of obesity is increasing in several populations, and is becoming an enormous problem among occupational/professional groups. The study determined the prevalence and risk factors of obesity among practicing nurses in three selected hospitals in the Kumasi metropolis. This cross-sectional study recruited 825 nurses from Suntreso, Manhyia and Kumasi South Hospitals. Structured questionnaire was used to obtain information on socio-demographic characteristics, and lifestyle behaviours of all participants. Obesity was assessed using body mass index (BMI), waist circumference (WC), waist-to-hip ratios (WHR) and Waist to height ratio (WHtR). The prevalence of obesity among nurses was 55.9% by WHtR, 35.7% by WC, 29.4% by BMI classification and 27.3% by WHR classification. The pattern of increased prevalence was higher among female nurses and nurses with high professional rank irrespective of the anthropometric parameters used. Logistic regression model indicates that taking meals late at night [odds ratio (OR) = 2.5 (1.1 to 5.7), p=0.0398], taking meals at stressful hours [OR=7.9 (2.1 to 29.8); p=0.0009], and fast food intake [OR=2.6 (1.1 to 6.0), p=0.0370) were independent risk factors of obesity classified by BMI. Taking meals at stressful hours [OR=3.33 (1.4 to 8.2); p=0.0091] and being female [OR=26.8 (3.5 to 207.7); p<0.0001] were significant independent risk factors of obesity classified by WC. Using WHR, being a female [OR=22.1 (1.31 to 380.0); p=0.0009] was an independent risk factor for obesity. Taking meals late at night [OR=2.4 (1.2 to 4.7); p=0.0121], taking meals at stressful hours [OR=3.1 (1.3 to 7.4); p=0.0148], and physical inactivity [OR=2.2 (1.0 to 4.5); p=0.0478] and being a female [OR=4.6 (1.7 to 12.4), p=0.0024] were independent risk factors of obesity using WHtR. Obesity among nurses in the Kumasi metropolis is on a rise and of public health significance. The need to foster healthy lifestyle is essential in health profession and pertinent to prevent obesity and future morbidity and mortality associated with cardiovascular metabolic risk factors.Journal of Medical and Biomedical Sciences (2016) 5(3), 45-55Keywords: Obesity, overweight, risk, practicing Nurses, Kumasi Metropolis


Sexual Health ◽  
2004 ◽  
Vol 1 (3) ◽  
pp. 145 ◽  
Author(s):  
M. F. D. Baay ◽  
V. Verhoeven ◽  
D. Avonts ◽  
J. B. Vermorken

Background: The current cervical cancer prevention strategy is exclusively directed towards screening, without taking into account any relationship with sexual risk factors. The introduction of human papillomavirus (HPV) detection into the screening procedure implicates that we should give attention to this relationship. The aim of this study was to investigate what knowledge women have of the relation between HPV and cervical cancer. Methods: Rather than asking about HPV specifically, we suggested 20 risk factors for the development of cervical cancer, including viral infection, and asked 73 women visiting their general practitioner, 67 women visiting a lecture on risk factors for cervical cancer and 28 female students in biomedical sciences to rate the importance of these risk factors on a scale of 1–5. Results: Genetic factors were rated highest with a mean score of 4.5. Bacterial infection ranked second highest with a mean score of 3.8. Smoking ranked fourth at a mean score of 3.6, whereas viral infection shared the sixth place with number of sexual partners with a mean score of 3.4. The presence of high voltage power lines and physical activity appropriately scored the last two places at 2.4 and 2.2, respectively. Twenty-one women suggested a role for sexually transmitted agents, but only five women (3.1%) could actually pinpoint HPV. Conclusion: This enquiry indicates that the risk factor ‘genetic factors’ was over-rated, while knowledge of the most important risk factors, i.e. smoking and sexual habits and (sexually transmitted) infections, would appear to be present to a moderate level in our population. However, knowledge of the role of HPV in cervical cancer development is lacking.


2004 ◽  
Author(s):  
Chandrani Liyanage ◽  
Manjula Hettiarachchi
Keyword(s):  

2019 ◽  
Vol 133 (22) ◽  
pp. 2283-2299
Author(s):  
Apabrita Ayan Das ◽  
Devasmita Chakravarty ◽  
Debmalya Bhunia ◽  
Surajit Ghosh ◽  
Prakash C. Mandal ◽  
...  

Abstract The role of inflammation in all phases of atherosclerotic process is well established and soluble TREM-like transcript 1 (sTLT1) is reported to be associated with chronic inflammation. Yet, no information is available about the involvement of sTLT1 in atherosclerotic cardiovascular disease. Present study was undertaken to determine the pathophysiological significance of sTLT1 in atherosclerosis by employing an observational study on human subjects (n=117) followed by experiments in human macrophages and atherosclerotic apolipoprotein E (apoE)−/− mice. Plasma level of sTLT1 was found to be significantly (P<0.05) higher in clinical (2342 ± 184 pg/ml) and subclinical cases (1773 ± 118 pg/ml) than healthy controls (461 ± 57 pg/ml). Moreover, statistical analyses further indicated that sTLT1 was not only associated with common risk factors for Coronary Artery Disease (CAD) in both clinical and subclinical groups but also strongly correlated with disease severity. Ex vivo studies on macrophages showed that sTLT1 interacts with Fcɣ receptor I (FcɣRI) to activate spleen tyrosine kinase (SYK)-mediated downstream MAP kinase signalling cascade to activate nuclear factor-κ B (NF-kB). Activation of NF-kB induces secretion of tumour necrosis factor-α (TNF-α) from macrophage cells that plays pivotal role in governing the persistence of chronic inflammation. Atherosclerotic apoE−/− mice also showed high levels of sTLT1 and TNF-α in nearly occluded aortic stage indicating the contribution of sTLT1 in inflammation. Our results clearly demonstrate that sTLT1 is clinically related to the risk factors of CAD. We also showed that binding of sTLT1 with macrophage membrane receptor, FcɣR1 initiates inflammatory signals in macrophages suggesting its critical role in thrombus development and atherosclerosis.


2011 ◽  
Vol 21 (2) ◽  
pp. 59-62
Author(s):  
Joseph Donaher ◽  
Christina Deery ◽  
Sarah Vogel

Healthcare professionals require a thorough understanding of stuttering since they frequently play an important role in the identification and differential diagnosis of stuttering for preschool children. This paper introduces The Preschool Stuttering Screen for Healthcare Professionals (PSSHP) which highlights risk factors identified in the literature as being associated with persistent stuttering. By integrating the results of the checklist with a child’s developmental profile, healthcare professionals can make better-informed, evidence-based decisions for their patients.


2010 ◽  
Vol 20 (3) ◽  
pp. 76-83 ◽  
Author(s):  
Joseph Donaher ◽  
Tom Gurrister ◽  
Irving Wollman ◽  
Tim Mackesey ◽  
Michelle L. Burnett

Parents of children who stutter and adults who stutter frequently ask speech-language pathologists to predict whether or not therapy will work. Even though research has explored risk-factors related to persistent stuttering, there remains no way to determine how an individual will react to a specific therapy program. This paper presents various clinicians’answers to the question, “What do you tell parents or adults who stutter when they ask about cure rates, outcomes, and therapy efficacy?”


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