scholarly journals On the Relationship of Socio-Economic Status and Risk Factors for Alcoholic Liver Disease in North China

2018 ◽  
Vol 10 (4) ◽  
pp. 35 ◽  
Author(s):  
Haixia Wang ◽  
Qiling Yin ◽  
Xiaowei Zhang ◽  
Cuiqin Zhang
Keyword(s):  
Risk Factors ◽  
Liver Disease ◽  
Alcoholic Liver Disease ◽  
Dietary Habits ◽  
Disease Risk ◽  
Economic Status ◽  
Shandong Province ◽  
Influential Factor ◽  
Alcoholic Beverages ◽  
Socio Economic Status

BACKGROUND: The present article analyses the association between socioeconomic status (includes education, occupation, income and marriage) and alcoholic liver disease (ALD) risk factors (age, gender, obesity, quantity and duration of alcohol intake, alcoholic beverages, drinking patterns) in Taishan area of Shandong province, to provide scientific basis for the prevention of alcoholic liver disease for the people who mostly need it in north China.METHODS: Across-sectional survey of  over 18--year-old inhabitants in Shandong Province in 2011 used multistage, randomized clustered sampling to identify 8186 subjects; 7295 (89.12%) of them were interviewed. Questionnaires, designed by co-working of epidemiologists and hepatologists, included demographic characteristics, current medication use, medical history and health-relevant behaviors, i.e. alcohol consumption, dietary habits and physical activities. Anthropometric measurements, biochemical tests and abdominal ultrasonography were carried out. The sample was determined by Chi-square test, covariance analysis and logistic regression analysis.RESULTS: Because of the small number of female drinkers, alcoholic liver disease prevalence of female was obviously lower than that of male, the very study of the male drinkers is more meaningful and can be represent the whole drinkers group to some extent. Among the four socio-economic status (SES) indicators the marriage status seemed to be the most influential factor. People (men or women) without spouse had higher risk of alcoholic liver disease risk factors than those who had spouse. The risk of people who have different occupation is different. The higher education was associated with risk of ALD.CONCLUSION: Marriage status seemed to be the most important measure of the socioeconomic indicators in relation to the alcoholic liver disease risk factors in the study of population. There is obvious relation between occupation status and alcoholic liver disease risk factors in men. The lower occupation had higher alcoholic liver disease risk factors. People with higher income and education had higher levels of drinking risk factors and lower level of obesity risk factors.

Coronary heart disease risk factors in young people of differing socio-economic status

2005 ◽  
Vol 11 (2) ◽  
pp. 171-187 ◽  
Author(s):  
Non-Eleri Thomas ◽  
Stephen-Mark Cooper ◽  
Simon P. Williams ◽  
Julien S. Baker ◽  
Bruce Davies
Keyword(s):  
Risk Factors ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Young People ◽  
Coronary Heart Disease Risk ◽  
Disease Risk ◽  
Economic Status ◽  
Socio Economic Status ◽  
Heart Disease Risk Factors ◽  
Heart Disease Risk

Regulatory effect of volatile compounds in fermented alcoholic beverages on gut microbiota and serum metabolism in mouse model

2021 ◽  
Author(s):  
Mei Ji ◽  
Cheng Fang ◽  
Wei Jia ◽  
Hai Du ◽  
Yan Xu
Keyword(s):  
Risk Factor ◽  
Liver Disease ◽  
Mouse Model ◽  
Gut Microbiota ◽  
Volatile Compounds ◽  
Alcoholic Liver Disease ◽  
Alcoholic Beverages ◽  
Regulatory Effect ◽  
Main Risk Factor

Ethanol (EtOH) is the main risk factor for alcoholic liver disease. However, fermented alcoholic beverages contain not only ethanol but also various volatile compounds. Currently, effects of volatile compounds in...

scholarly journals Influence of socio-economic status on Shiga toxin-producing Escherichia coli (STEC) infection incidence, risk factors and clinical features

2019 ◽  
Vol 147 ◽  
Author(s):  
N. L. Adams ◽  
L. Byrne ◽  
T. C. Rose ◽  
G. K. Adak ◽  
C. Jenkins ◽  
...  
Keyword(s):  
Risk Factors ◽  
Escherichia Coli ◽  
Shiga Toxin ◽  
Economic Status ◽  
Care Seeking ◽  
Socio Economic Status ◽  
Accident And Emergency ◽  
Incidence Risk ◽  
Potential Risk Factors

Abstract Shiga toxin-producing Escherichia coli (STEC) infection can cause serious illness including haemolytic uraemic syndrome. The role of socio-economic status (SES) in differential clinical presentation and exposure to potential risk factors amongst STEC cases has not previously been reported in England. We conducted an observational study using a dataset of all STEC cases identified in England, 2010–2015. Odds ratios for clinical characteristics of cases and foodborne, waterborne and environmental risk factors were estimated using logistic regression, stratified by SES, adjusting for baseline demographic factors. Incidence was higher in the highest SES group compared to the lowest (RR 1.54, 95% CI 1.19–2.00). Odds of Accident and Emergency attendance (OR 1.35, 95% CI 1.10–1.75) and hospitalisation (OR 1.71, 95% CI 1.36–2.15) because of illness were higher in the most disadvantaged compared to the least, suggesting potential lower ascertainment of milder cases or delayed care-seeking behaviour in disadvantaged groups. Advantaged individuals were significantly more likely to report salad/fruit/vegetable/herb consumption (OR 1.59, 95% CI 1.16–2.17), non-UK or UK travel (OR 1.76, 95% CI 1.40–2.27; OR 1.85, 95% CI 1.35–2.56) and environmental exposures (walking in a paddock, OR 1.82, 95% CI 1.22–2.70; soil contact, OR 1.52, 95% CI 2.13–1.09) suggesting other unmeasured risks, such as person-to-person transmission, could be more important in the most disadvantaged group.

scholarly journals Healthy dietary habits in relation to social determinants and lifestyle factors

1999 ◽  
Vol 81 (3) ◽  
pp. 211-220 ◽  
Author(s):  
Lars Johansson ◽  
Dag S. Thelle ◽  
Kari Solvoll ◽  
Gunn-Elin Aa. Bjørneboe ◽  
Christian A. Drevon
Keyword(s):  
Social Status ◽  
Fruits And Vegetables ◽  
Dietary Habits ◽  
Economic Status ◽  
Multiple Regression Model ◽  
Healthy Diet ◽  
Dietary Survey ◽  
Food Frequency ◽  
Men And Women ◽  
Socio Economic Status

The aim of the present study was to evaluate the importance of social status and lifestyle for dietary habits, since these factors may influence life expectancy. We studied the association of four indicators for healthy dietary habits (fruits and vegetables, fibre, fat and Hegsted score) with sex, age, socio-economic status, education, physical leisure exercise, smoking and personal attention paid to keeping a healthy diet. Data were gathered with a self-administered quantitative food-frequency questionnaire distributed to a representative sample of Norwegian men and women aged 16–79 years in a national dietary survey, of whom 3144 subjects (63%) responded. Age and female sex were positively associated with indicators for healthy dietary habits. By separate evaluation length of education, regular physical leisure exercise and degree of attention paid to keeping a healthy diet were positively associated with all four indicators for healthy dietary habits in both sexes. Socio-economic status, location of residence and smoking habits were associated with from one to three indicators for healthy dietary habits. In a multiple regression model, age, education and location of residence together explained from 1 to 9% of the variation (R2) in the four dietary indicators. Length of education was significantly associated with three of four dietary indicators both among men and women. By including the variable ‘attention paid to keeping a healthy diet’ in the model, R2 increased to between 4 and 15% for the four dietary indicators. Length of education remained correlated to three dietary indicators among women, and one indicator among men, after adjusting for attention to healthy diet, age and location of residence. Residence in cities remained correlated to two indicators among men, but none among women, after adjusting for age, education and attention to healthy diet. In conclusion, education was associated with indicators of a healthy diet. Attention to healthy diet showed the strongest and most consistent association with all four indicators for healthy dietary habits in both sexes. This suggests that personal preferences may be just as important for having a healthy diet as social status determinants.

scholarly journals Alkoholos májbetegség: a genetikai-epigenetikai tényezők szerepe és az absztinencia hatása

2019 ◽  
Vol 160 (14) ◽  
pp. 524-532 ◽  
Author(s):  
Alajos Pár ◽  
Gabriella Pár
Keyword(s):  
Risk Factors ◽  
Liver Disease ◽  
Environmental Factors ◽  
Alcoholic Liver Disease ◽  
Liver Toxicity ◽  
Hepatitis Virus ◽  
Alcoholic Cirrhosis ◽  
Protective Role ◽  
Micro Rna ◽  
Alcoholic Fatty Liver

Abstract: The pathogenesis of alcoholic liver disease depends not only on the toxic effects of alcohol, but also on the complex interaction of host’s and environmental factors. Thus, the genetic pre-disposition, co-morbidities and behavioral factors all play a role in the individual variations in the disease outcomes. On the other hand, the essential part of the therapeutic strategy is the complete withdrawal of the harmful etiological agent. The present paper is devoted to overview the genetics, the environmental factors and the effects of abstinence in alcoholic liver disease. Genetic variants in two enzymes involved in the metabolism of ethanol, alcohol-dehydrogenase ADH1B *2 and aldehyde-dehydrogenase ALDH2 *2 through increasing the blood level of acetaldehyde, may play a “protective” role against alcoholism. The P450 CYP2E1 *5 c2, an inducible microsomal oxidase, upregulated by ethanol and by formation of acetaldehyde and reactive oxygen species, increases liver toxicity. Three novel gene polymorphisms – such as the patatin-like phospholipase domain-containing 3 (PNPLA3 I148M C>G), the transmembrane 6 superfamily member 2 (TM6SF2 E167K), and the membrane-bound O-acyltransferase domain-containing 7 (MB0AT7 rs641738 C>T) – have been proven as risk factors of steatosis, fibrosis and even hepatocellular carcinoma in both alcoholic and non-alcoholic fatty liver disease patients. Alcohol-induced epigenetic effects, reversible but inheritable gene expression alterations – as histon modulations, DNA methylation and micro-RNA-s – are of importance in the pathogenesis as well, and in the future, they may serve as diagnostic markers and therapeutic targets. Women are at greater risk of developing alcoholic cirrhosis, furthermore, malnutrition, obesity, diabetes, smoking, and hepatitis virus infections are also risk factors. Alcoholic liver disease should be regarded as a preventable disease. Several clinical studies revealed that abstinence may result in the regression of steatohepatitis and fibrosis, compensation of cirrhosis, improving disease outcome and increasing survival even in patients with advanced stages. Early diagnosis and multidisciplinary interventions are highly required to achieve long-term abstinence and to prevent alcoholic cirrhosis. Orv Hetil. 2019; 160(14): 524–532.

scholarly journals The Relationship between Self-Rated Economic Status and Falls among the Elderly in Shandong Province, China

2020 ◽  
Vol 17 (6) ◽  
pp. 2150
Author(s):  
Zhuang Hong ◽  
Lingzhong Xu ◽  
Jinling Zhou ◽  
Long Sun ◽  
Jiajia Li ◽  
...  
Keyword(s):  
Risk Factors ◽  
Urban Areas ◽  
Economic Status ◽  
The Elderly ◽  
Shandong Province ◽  
Prevention Measures ◽  
Logistic Regression Models ◽  
Economic Level ◽  
Significant Difference ◽  
The Relationship

(1) Background: Older people are more vulnerable and likely to have falls and the consequences of these falls place a heavy burden on individuals, families and society. Many factors directly or indirectly affect the prevalence of falls. The aims of this study were to understand the prevalence and risk factors of falls among the elderly in Shandong, China; the relationship between economic level and falls was also preliminary explored. (2) Methods: Using a multi-stage stratified sampling method, 7070 elderly people aged 60 and over were selected in Shandong Province, China. General characteristics and a self-rated economic status were collected through face to face interviews. Chi-square tests, rank sum tests and two logistic regression models were performed as the main statistical methods. (3) Results: 8.59% of participants reported that they had experienced at least one fall in the past half year. There was a significant difference in experienced falls regarding gender, residence, marital status, educational level, smoking, drinking, hypertension, diabetes, coronary disease, and self-reported hearing. The worse the self-rated economic status, the higher the risk of falling, (poor and worried about livelihood, OR = 3.60, 95%; CI = 1.76–7.35). (4) Conclusions: Women, hypertension, diabetes and self-reported hearing loss were identified as the risk factors of falls in the elderly. The difference of economic level affects the falls of the elderly in rural and urban areas. More fall prevention measures should be provided for the elderly in poverty.

scholarly journals Understanding Regional Risk Factors for Cancer: A Cluster Analysis of Lifestyle, Environment and Socio-Economic Status in Poland

2020 ◽  
Vol 12 (21) ◽  
pp. 9080
Author(s):  
Dawid Majcherek ◽  
Marzenna Anna Weresa ◽  
Christina Ciecierski
Keyword(s):  
Risk Factors ◽  
Cluster Analysis ◽  
Economic Status ◽  
Prevention Policy ◽  
Sports Activity ◽  
Socio Economic Status ◽  
Policy Interventions ◽  
Anti Cancer ◽  
Northern Regions ◽  
Industrial Regions

To date, no results have been published regarding cluster analysis of risk factors for cancer in Poland. Many cancer deaths are preventable through the modification of cancer risk behaviours. This study explores the multidisciplinary connection between lifestyle, environment and socio-economic status (SES). Cluster analyses indicate that major metropolitan areas and large industrial regions differ significantly in terms of SES, lifestyle and environment when compared with other parts of Poland. Our findings show that in order for interventions to be effective, cancer-prevention policy should be addressed on both local and national scales. While anti-cancer policies in Poland’s industrial regions should focus on air pollution, the country’s northern regions should aim to curb smoking, increase sports activity and improve SES. Policy interventions must target the root causes of cancer in each region of Poland and must account for SES.

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