scholarly journals Dialoger om verdier i grunnskolens formålsparagraf – med minnematerialet fra 22. juli som læremiddel

Prismet ◽  
1970 ◽  
pp. 171-184
Author(s):  
Ingebjørg Stubø ◽  
Synnøve Markeng
Keyword(s):  
Young People ◽  
Children And Adolescents ◽  
Theoretical Perspective ◽  
Central Values ◽  
Starting Point ◽  
Good Starting Point ◽  
Education Act ◽  
Norwegian Education ◽  
Human Worth

In the aftermath of the shooting and killing of young people on Utøya island and the bombing of government buildings on July 22nd 2011, children and adolescents put down texts and drawings on spontaneous memorials in the Oslo area1..Love and togetherness, life and human worth are often the values these utterances focus on. These are values closely related to central values in the objects clause («formåls-paragrafen») of the Norwegian Education Act, such as respect for human worth, compassion, diversity, equality and solidarity. This article highlights how children’s memorial texts can be a good starting point for conversation when the theme of the teaching is preamble values. The article deals with two forms of dialogue, philosophical conversations and teacher-led dialogues. The article’s main theoretical perspective is taken from Laila Aase’s presentation of the literary conversation in school, supplemented by perspectives that underlie the philosophical conversations and teacher-led dialogues.   Nøkkelord: Verdier, læringsverdier, 22. juli 2011, dialog, filosofisk samtale

scholarly journals Verdier i formålsparagraf og minnematerialet etter 22. juli 2011

Prismet ◽  
1970 ◽  
pp. 139-153
Author(s):  
Sidsel Lied ◽  
Ingebjørg Stubø
Keyword(s):  
Young People ◽  
Theoretical Perspective ◽  
Central Values ◽  
Education Act ◽  
Norwegian Education ◽  
Human Worth

Many of the texts and drawings from spontaneous memorial places in the Oslo area in the days after the bombing of government buildings and  the shooting and killing of young people on Utøya island on July 22nd 2011, are made by children. The main focus of this article is what values these memorial utterances show that children considered important and worth fighting for in the aftermath of this event. Love and togetherness, life and human worth were often in focus in these utterances – utterances that are closely related to central values in the objects clause («formålsparagrafen») of the Norwegian Education Act, such as love for one’s neighbour, respect for human worth, diversity and solidarity. But children’s memorial utterances also indicate that the very fight for these values sometimes puts the same values under pressure: in some texts and drawings the terrorist is dehumanised and deprived of his human worth. The article gives examples of and discusses these phenomena. The theoretical perspective used in the article is Gunther Kress and Theo van Leeuwen’s grammar of western visual design.Nøkkelord: verdier, 22. juli, barns verdier, verdier i norsk skole, visuell meningsskaping

scholarly journals Addition for Measuring the Ability to Understand Regularity and to Extrapolate

2021 ◽  
Author(s):  
Ippei Fujisawa ◽  
Ryota Kanai
Keyword(s):  
Reinforcement Learning ◽  
Computer Science ◽  
Simple Structure ◽  
Theoretical Perspective ◽  
General Purpose ◽  
Training Dataset ◽  
Test Dataset ◽  
Starting Point ◽  
Good Starting Point ◽  
Future Direction

In this paper, we discuss the possibility that elementary arithmetic, such as addition and other arithmetic operations, would be useful as a benchmark for measuring the ability to extrapolate which is considered important for the realization of general-purpose intelligence. Understanding addition can be regarded as performing addition of arbitrary digits correctly by memorizing and applying the rules of addition of single digits, and by learning the rules of carrying. We propose a benchmark in which we prepare a small training dataset that is considered sufficient to reveal the algebra of addition, and measure the accuracy using a test dataset that requires large multi-digit operations. Our benchmark has the following advantages over the datasets usually used in recognition tasks and reinforcement learning. Its simple structure makes it easy to generate datasets, adjust and extend the difficulty, identify inductive biases, and allows for discussion from a theoretical perspective in computer science like program synthesis. We hope that the elementary arithmetic benchmark will reveal functions missing in current AI systems, and also provide a good starting point for developing them. In particular, we speculate that the use of the knowledge may be required for a system to compute correctly for arbitrary digits. Finally, based on these insights, we propose a future direction for the development of systems with extrapolation capabilities.

YOUTH EXPECTATIONS OF SMART CITY LIVING: AN IMPORTANCE- PERFORMANCE ANALYSIS OF YOUNG RESIDENTS’ PERSPECTIVES OF CITY GOVERNMENT

2017 ◽  
Vol 14 (1) ◽  
pp. 118-128
Author(s):  
Jason Cohen ◽  
Judy Backhouse ◽  
Omar Ally
Keyword(s):  
Performance Analysis ◽  
Young People ◽  
Smart City ◽  
Smart Cities ◽  
City Government ◽  
Diagnostic Tools ◽  
City Management ◽  
Bottom Up ◽  
Starting Point ◽  
The City

Young people are important to cities, bringing skills and energy and contributing to economic activity. New technologies have led to the idea of a smart city as a framework for city management. Smart cities are developed from the top-down through government programmes, but also from the bottom-up by residents as technologies facilitate participation in developing new forms of city services. Young people are uniquely positioned to contribute to bottom-up smart city projects. Few diagnostic tools exist to guide city authorities on how to prioritise city service provision. A starting point is to understand how the youth value city services. This study surveys young people in Braamfontein, Johannesburg, and conducts an importance-performance analysis to identify which city services are well regarded and where the city should focus efforts and resources. The results show that Smart city initiatives that would most increase the satisfaction of youths in Braamfontein  include wireless connectivity, tools to track public transport  and  information  on city events. These  results  identify  city services that are valued by young people, highlighting services that young people could participate in providing. The importance-performance analysis can assist the city to direct effort and scarce resources effectively.

scholarly journals Discovery and Optimization of Selective Inhibitors of Meprin α (Part I)

2021 ◽  
Vol 14 (3) ◽  
pp. 203 ◽  
Author(s):  
Shurong Hou ◽  
Juan Diez ◽  
Chao Wang ◽  
Christoph Becker-Pauly ◽  
Gregg B. Fields ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
De Novo ◽  
Selective Inhibitors ◽  
Preclinical Development ◽  
Starting Point ◽  
Good Starting Point ◽  
Parallel Screening ◽  
Low Cytotoxicity

Meprin α and β are zinc-dependent proteinases implicated in multiple diseases including cancers, fibrosis, and Alzheimer’s. However, until recently, only a few inhibitors of either meprin were reported and no inhibitors are in preclinical development. Moreover, inhibitors of other metzincins developed in previous years are not effective in inhibiting meprins suggesting the need for de novo discovery effort. To address the paucity of tractable meprin inhibitors we developed ultrahigh-throughput assays and conducted parallel screening of >650,000 compounds against each meprin. As a result of this effort, we identified five selective meprin α hits belonging to three different chemotypes (triazole-hydroxyacetamides, sulfonamide-hydroxypropanamides, and phenoxy-hydroxyacetamides). These hits demonstrated a nanomolar to micromolar inhibitory activity against meprin α with low cytotoxicity and >30-fold selectivity against meprin β and other related metzincincs. These selective inhibitors of meprin α provide a good starting point for further optimization.

scholarly journals Advances on the Implementation of Circular Economy Techniques in Rural Areas in Colombia under a Sustainable Development Framework

2021 ◽  
Vol 13 (7) ◽  
pp. 3816
Author(s):  
Javier Rodrigo-Ilarri ◽  
Camilo-A. Vargas-Terranova ◽  
María-Elena Rodrigo-Clavero ◽  
Paula-A. Bustos-Castro
Keyword(s):  
Sustainable Development ◽  
Waste Management ◽  
Circular Economy ◽  
Rural Areas ◽  
Development Framework ◽  
Starting Point ◽  
Management Plans ◽  
Good Starting Point ◽  
Depressed Regions ◽  
First Time

For the first time in the scientific literature, this research shows an analysis of the implementation of circular economy techniques under sustainable development framework in six municipalities with a depressed economy in Colombia. The analysis is based on solid waste data production at a local scale, the valuation of the waste for subsequent recycling, and the identification and quantification of the variables associated with the treatment and final disposal of waste, in accordance with the Colombian regulatory framework. Waste generation data are obtained considering three different scenarios, in which a comparison between the simulated values and those established in the management plans are compared. Important differences have been identified between the waste management programs of each municipality, specifically regarding the components of waste collection, transportation and disposal, participation of environmental reclaimers, and potential use of materials. These differences are fundamentally associated with the different administrative processes considered for each individual municipality. This research is a good starting point for the development of waste management models based on circular economy techniques, through the subsequent implementation of an office tool in depressed regions such as those studied.

scholarly journals Socioeconomic Differences in Walking Time of Children and Adolescents to Public Green Spaces in Urban Areas—Results of the German Environmental Survey (2014–2017)

2021 ◽  
Vol 18 (5) ◽  
pp. 2326
Author(s):  
Julia Rehling ◽  
Christiane Bunge ◽  
Julia Waldhauer ◽  
André Conrad
Keyword(s):  
Young People ◽  
Children And Adolescents ◽  
Urban Areas ◽  
Green Space ◽  
Positive Impact ◽  
Green Spaces ◽  
Environmental Survey ◽  
Urban Green Spaces ◽  
Public Green Space ◽  
Walking Time

Public green spaces have a high potential for a positive impact on people’s health and wellbeing, especially in urban areas. Studies on environmental justice indicate socially unequal access possibilities to urban green spaces. This article presents results on associations between individual socioeconomic position (SEP) and walking time from home to public green spaces in young people living in urban areas with more than 20,000 inhabitants in Germany. Data were derived from the German Environmental Survey for Children and Adolescents 2014–2017 (GerES V), the environmental module of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS Wave 2). The sample comprises 1149 participants aged 3 to 17 years. A total of 51.5% of the participants reach a public green space on foot within five and 72.8% within ten minutes from home. The lower the participant’s SEP, the longer the walking time. Logistic regression models controlling for age group, sex, migration background, and region of residence show that participants with a low SEP have a significantly higher risk (odds ratio = 1.98; 95% confidence interval: 1.31–2.99) of needing more than ten minutes to walk from home to a public green space than participants with a high SEP. GerES V data indicate that young people living in urban areas in Germany do not equally benefit from the health-promoting potential of green spaces, which is an important aspect of environmental health inequalities.

scholarly journals Temporal trends in annual incidence rates for psychiatric disorders and self-harm among children and adolescents in the UK, 2003–2018

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Lukasz Cybulski ◽  
Darren M. Ashcroft ◽  
Matthew J. Carr ◽  
Shruti Garg ◽  
Carolyn A. Chew-Graham ◽  
...  
Keyword(s):  
Eating Disorders ◽  
Young People ◽  
Anxiety Disorders ◽  
Children And Adolescents ◽  
Autism Spectrum ◽  
Incidence Rates ◽  
Annual Incidence ◽  
Health Crisis ◽  
Self Harm ◽  
The Uk

Abstract Background There has been growing concern in the UK over recent years that a perceived mental health crisis is affecting children and adolescents, although published epidemiological evidence is limited. Methods Two population-based UK primary care cohorts were delineated in the Aurum and GOLD datasets of the Clinical Practice Research Datalink (CPRD). We included data from 9,133,246 individuals aged 1–20 who contributed 117,682,651 person-years of observation time. Sex- and age-stratified annual incidence rates were estimated for attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) (age groups: 1–5, 6–9, 10–12, 13–16, 17–19), depression, anxiety disorders (6–9, 10–12, 13–16, 17–19), eating disorders and self-harm (10–12, 13–16, 17–19) during 2003–2018. We fitted negative binomial regressions to estimate incidence rate ratios (IRRs) to examine change in incidence between the first (2003) and final year (2018) year of observation and to examine sex-specific incidence. Results The results indicated that the overall incidence has increased substantially in both boys and girls in between 2003 and 2018 for anxiety disorders (IRR 3.51 95% CI 3.18–3.89), depression (2.37; 2.03–2.77), ASD (2.36; 1.72–3.26), ADHD (2.3; 1.73–3.25), and self-harm (2.25; 1.82–2.79). The incidence for eating disorders also increased (IRR 1.3 95% CI 1.06–1.61), but less sharply. The incidence of anxiety disorders, depression, self-harm and eating disorders was in absolute terms higher in girls, whereas the opposite was true for the incidence of ADHD and ASD, which were higher among boys. The largest relative increases in incidence were observed for neurodevelopmental disorders, particularly among girls diagnosed with ADHD or ASD. However, in absolute terms, the incidence was much higher for depression and anxiety disorders. Conclusion The number of young people seeking help for psychological distress appears to have increased in recent years. Changes to diagnostic criteria, reduced stigma, and increased awareness may partly explain our results, but we cannot rule out true increases in incidence occurring in the population. Whatever the explanation, the marked rise in demand for healthcare services means that it may be more challenging for affected young people to promptly access the care and support that they need.

Industry-Sponsored Medical Education — In the Quest for Professional Integrity and Legal Certainty

2007 ◽  
Vol 14 (4) ◽  
pp. 313-319
Author(s):  
Benedikt Buchner
Keyword(s):  
Medical Education ◽  
Self Regulation ◽  
State Regulation ◽  
General Question ◽  
Legal Certainty ◽  
European Directive ◽  
Starting Point ◽  
Good Starting Point ◽  
Advertising Law ◽  
The Right

AbstractIndustry-sponsored medical education is a much disputed issue. So far, there has been no regulatory framework which provides clear and definite rules as to whether and under what circumstances the sponsorship of medical education is acceptable. State regulation does not exist, or confines itself to a very general principle. Professional regulation, even though applied frequently, is rather vague and indefinite, raising the general question as to whether self-regulation is the right approach at all. Certainly, self-regulation by industry cannot and should not replace other regulatory approaches. Ultimately, advertising law in general and the European Directive 2001/83/EC specifically, might be a good starting point in providing legal certainty and ensuring the independence of medical education. Swiss advertising law illustrates how the principles of the European Directive could be implemented clearly and unambiguously.

scholarly journals Multiple Myeloma Inhibitory Activity of Plant Natural Products

Cancers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2678
Author(s):  
Karin Jöhrer ◽  
Serhat Sezai Ҫiҫek
Keyword(s):  
Multiple Myeloma ◽  
Natural Products ◽  
Myeloma Cell ◽  
Myeloma Cell Line ◽  
Antiproliferative Effects ◽  
Plant Natural Products ◽  
Starting Point ◽  
Human Myeloma Cell Line ◽  
Group A ◽  
Good Starting Point

A literature search on plant natural products with antimyeloma activity until the end of 2020 resulted in 92 compounds with effects on at least one human myeloma cell line. Compounds were divided in different compound classes and both their structure–activity-relationships as well as eventual correlations with the pathways described for Multiple Myeloma were discussed. Each of the major compound classes in this review (alkaloids, phenolics, terpenes) revealed interesting candidates, such as dioncophyllines, a group of naphtylisoquinoline alkaloids, which showed pronounced and selective induction of apoptosis when substituted in position 7 of the isoquinoline moiety. Interestingly, out of the phenolic compound class, two of the most noteworthy constituents belong to the relatively small subclass of xanthones, rendering this group a good starting point for possible further drug development. The class of terpenoids also provides noteworthy constituents, such as the highly oxygenated diterpenoid oridonin, which exhibited antiproliferative effects equal to those of bortezomib on RPMI8226 cells. Moreover, triterpenoids containing a lactone ring and/or quinone-like substructures, e.g., bruceantin, whitaferin A, withanolide F, celastrol, and pristimerin, displayed remarkable activity, with the latter two compounds acting as inhibitors of both NF-κB and proteasome chymotrypsin-like activity.

Compulsion to Repeat

2017 ◽  
pp. 9-35
Author(s):  
Mavis Reimer ◽  
Deanna England ◽  
Melanie Dennis Unrau ◽  
Nyala Ali
Keyword(s):  
Nineteenth Century ◽  
Young People ◽  
Children And Adolescents ◽  
Literary Fiction ◽  
High Quality ◽  
Series Fiction ◽  
Compulsion To Repeat

Beginning of the article: There is a curious gap in the scholarship on texts for young people: while series fiction has been an important stream of publishing for children and adolescents at least since the last decades of the nineteenth century, the scholarship on these texts has not been central to the development of theories on and criticism of texts for young people. The focus of scholarship is much more likely to be on stand-alone, high-quality texts of literary fiction.

Sign in / Sign up

Export Citation Format

Share Document