scholarly journals Evolvulus alsinoides (Linn.) Linn.: A Revitalizer

2021 ◽  
Author(s):  
Harshavardhini Kuppusamy R ◽  
Jananipriya Srinivasan ◽  
Pavithra Sundaramoorthy ◽  
Kannan Kilavan Packiam

Herbal medicines are utilized as traditional and alternative therapy to precisely restore declining metabolic functions. Herbal bioactive claims its rewards for their effectiveness, safety, and acceptability. Evolvulus alsinoides (Linn.) Linn. is a Virya herb from Convolvulaceae with Tridoshhara, Majjadhatu Rasayan, Vajikarak, Chedan, and Nidrajanan properties. In Ayurvedic medicine, the whole plant is used in the treatment of neurodegenerative diseases as brain tonic, amnesia and asthma, epilepsy and as a hepatoprotective. The phytochemical analysis has reported the existence of biomolecules such as β-sitosterol, scopolin, scopoletin, umbelliferon, triacontane, shankpushpine and betaine. A thorough review of classical as well as contemporary literature study has been done on Evolvulus alsinoides (Linn.) Linn. to validate the pharmacological actions and cytotoxicity effects on various cell lines.

2021 ◽  
Vol 11 (4) ◽  
pp. 4178-4191

Ayurveda, often known as Ayurvedic medicine, is a customized system of the traditional system of medicine with historical roots in the Indian subcontinent. This alternative medicine system has been used for more than 5,000 years in India, and it is grounded on a holistic view of treatment that stimulates and supports equilibrium in diverse facets of human life: the body, soul, and mind. A great variety of herbs and plants are used in Ayurveda for numerous advantages; however, the popular Ayurvedic medicinal plants and formulations that are used to delay the aging of the human brain and improve memory consist of Ashwagandha (Withania somnifera), Turmeric (Curcuma longa), Brahmi (Bacopa monnieri), Shankhpushpi (Convolvulus pluricaulis, Evolvulus alsinoides, and other species), gotu kola (Centella asiatica), and guggulu (Commiphora mukul and correlated species) and a preparation identified as Brāhmī Ghṛita, containing Brahmi, Vacā (Acorus calamus), Kuṣṭha (Saussurea lappa), Shankhpushpi, and Purāṇa Ghṛita (old clarified butter/old ghee). One of the extremely common progressive neurodegenerative disorders is Alzheimer s disease (AD), which is characterized by profound memory loss ample enough to hinder social and occupational functioning. Globally, more than 20 million people are affected by this most common form of dementia. AD is characterized by a stealthy loss of memory, allied functional decline, and behavioral disturbances. With modern scientific methods, it is anticipated that this description can be further explored to disclose novel therapeutic pointers and push-start additional studies on the use of Ayurvedic medicine to prevent and treat AD. This paper reviews the clinical effects of a number of generally used types of herbal medicines to treat AD.


Author(s):  
Jigyasa Pathak ◽  
Aswathi M. P. ◽  
B. R. Patel ◽  
Harisha C. R. ◽  
Shukla Vinay J.

Background: Desmodium velutinum (Fabaceae) is one of the wild edible plants used traditionally to treat diarrhoea, haematuria, infertility and also externally used to treat scorpion bites. Though various parts of the plant have been used for therapeutic purpose, panchanga of the plant has not been studied for its Pharmacognostical and phytochemical characteristics in detail, following scientific parameters. Hence in the present study Desmodium velutinum whole plant has been studied for its pharmacognostical and phytochemical characters and compared with commonly used species Desmodium gangeticum. Methods: Whole plant of Desmodim velutinum was collected from Paikmal, Odisha and Desmodium gangeticum was collected from Junagarh, Gujarat in the month of November 2019 following good collection practices and shade dried. Pharmacognostical study and analytical study were performed following standard pharmacopoeial procedures. Results: Whole plant (Panchanga) of former is sweetish and latter is bitter. Powder microscopy of Desmodium gangeticum showed presence of rhomboidal crystals and lignified annular and spiral vessels. Desmodium velutinum showed presence of prismatic crystals and lignified pitted vessels. Physico-chemical analysis showed higher loss on drying in Desmodium gangeticum, and higher water soluble extractive values of Desmodium velutinum. Phytochemical estimation showed the presence of Proteins, tannins, and carbohydrates in both samples. HPTLC study showed similar Rf value 0.82 and 0.94 at 254 and 0.03 and 0.41 at 366nm. Conclusion: Basing upon the analytical and microscopic similarities Desmodium velutinum may be considered as substitute of Desmodium gangeticum


2021 ◽  
Vol 8 (8) ◽  
pp. 440-449
Author(s):  
Fathima Suman P ◽  
Minhaj . ◽  
I Arthi

This study deals with the Pharmacognostical physicochemical and phytochemical evaluation of the whole plant of Piper longum L. Pharmacognostical studies include macroscopic, microscopic and physicochemical evaluation. Physicochemical constants showed the values of total ash (10.8%), acid insoluble ash (1.3%), water soluble ash (3.2%), sulphated ash (12%), nitrated ash (1.85%), hot extraction (11.2%), water soluble extractive (4.8%), ethanol soluble extractive (12.4%), ether soluble extractive (5.6%), loss on drying (29%), swelling index (0.33) and mucilage content (0.8%) w/w. The preliminary phytochemical screening of the alcoholic extract showed presents of alkaloids, phenolic compounds, tannins, mucilage, starch, steroid and flavonoids. This study helps to development of different standard parameters of the plant which help the plant identification and authentication. Keywords: Piper longum L., Whole plant, Pharmacognostic, Phytochemical, Extract.


2020 ◽  
Vol 6 (2) ◽  
pp. 86-89
Author(s):  
Horadugoda Gamage Sujatha Pushpakanthi Hewageegana ◽  

Parinama shula is a disease of Annavaha Srotas characterized by pain during digestion of food, predominantly disturbing the daily life. This arise because of the faulty diet and habits. Parinama shula is a Tridoshaja vyadhi and out of tridosha, Vata dosha is most powerful and omnipotent and mobiliser of other dosha. Aggravated Vata either gets Avarana by Kapha, Pitta or combines with Kapha pitta to produce Shula in the abdominal region. Pain in Parinama shula is relieved by vomiting, immediately after intake of food and after complete digestion of food. Seven types of Parinama shula are mentioned in Ayurveda texts according to vitiated dosha. Vishnukranti kalka is mentioned in Sharanghadhara Samhita as a treatment for Parinama shula and it contains dry powder of the whole plant of Evolvulus alsinoides L. with cow ghee, bee honey and common sugar (1:2:2:I w/w). Vishnukranti kalka can comment as a strong and safe medicine with scientific evidences of ulcer healing property by in experimental and clinical studies for Parinama shula.


Author(s):  
Sowmya Kiran Rao

One of the most common endocrine disorder in females during reproductive age which leads to infertility, metabolic derangements, and also psychological impairments is polycystic ovary syndrome (PCOS). This syndrome has been known to increases the risk of type 2 diabetes, obesity, hypertension, cardiovascular diseases, lipid disorders, and also autoimmune thyroiditis. Impending complication list includes malignancies like breast and endometrial cancer. The actual cause of this syndrome is unknown, and perhaps, it could be due to a combination of various unmodifiable genetic factors and modifiable environmental factors. Several research studies have been carried out on management of PCOS, and many medicinal plants have been used as an alternative therapy for oligo/amenorrhoea, hyperandrogenism, and PCOS in women. The chapter gives an insight on PCOS, its management, and elucidates the effects of medicinal plants on PCOS.


2012 ◽  
Vol 2 (1) ◽  
pp. 6
Author(s):  
Jillian Borchard ◽  
Lily Mazzarella ◽  
Kevin Spelman

Modulation of nitric oxide (NO) may offer novel approaches in the treatment of a variety of diseases, such as Alzheimer’s, cardiovascular disease, and diabetes. A strategy in the modulation of NO expression may be through the use of herbal medicines. We surveyed medicinal plant research that utilized multicomponent extracts similar to what is used in clinical phytotherapy or in commerce, for demonstrated effects on NO activity. SciFinder Scholar, Pubmed, Web of Science, and BIOSIS were searched to identify human, animal, <em>in vivo</em>, <em>ex vivo </em>or <em>in vitro</em> research on botanical medicines, in whole or standardized form, that act on nitric oxide activity. iNOS was the most frequently investigated enzyme system and this system was up-regulated by many plant extracts, including, <em>Chicorium intybus, Cocos nucifera, Echinacea purpurea, Euonymus alatus, Ixeris dentate, Oldenlandia diffusa, Rhinacanthus nasutus, and Sida cordifolia. Many plant extracts down-regulated iNOS, including Centella asiatica, Dichroa Febrifuga, Echinacea purpurea, Evolvulus alsinoides, Fagonia cretica, Ginkgo biloba, Mollugo verticillata, Lactuca indica, Lithospermum erythrorhizon, Pueraria thunbergiana, and Taraxacum officinale</em>. The eNOS system was stimulated by <em>Eucommia ulmoides, Sida cordifolia</em>, and <em>Thymus pulegioides while Fagonia cretica, Rubia cordifolia</em> and <em>Tinospora cordifolia </em>down-regulated nNOS. Given the activity demonstrated by many of these herbal medicines, the increasing awareness of the effects of nitric oxide on a wide variety of disease processes and the growing incidence of these conditions in the population, further study of medicinal plants on nitric oxide signaling may lead to novel therapies and further insight into human physiology.


2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Yos Adi Prakoso ◽  
Chylen Setiyo Rini ◽  
Roeswandono Wirjaatmadja

The tropical area has a lot of herbal medicines such as Aloe vera (AV), Ananas comosus (AC), and Sansevieria masoniana (SM). All the three have a unique potential effect as an antibacterial and wound-healing promoter. The aim of this study is to explore the role of AV, AC, and SM on the skin wound infected with methicillin-resistant Staphylococcus aureus (MRSA). Forty-five adult female Sprague Dawley rats weighing 250–300 grams were divided into 5 groups. All the groups were exposed to two round full-thickness punch biopsy and infected with MRSA. The group C was the control group/untreated; group BC was treated with base cream/without extract; group AV was treated with 75% AV cream; group AC was treated with 75% AC cream, and group SM was treated with 75% SM cream. The wounds were observed on days 5, 10, and 15. The healing of skin wounds was measured by a percentage of closure, skin tensile strength, and histopathology. The result showed that AV, AC, and SM have a similar potential effect on healing in the wound that was infected with MRSA compared to the groups C and BC (P<0.05). It shows that all the three herbal formulations can be used as the alternative therapy to the wound infected with MRSA.


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