scholarly journals Action Mechanisms of Antirheumatic Herbal Medicines

2021 ◽  
Author(s):  
Nima Nakisa ◽  
Mahboobeh Ghasemzadeh Rahbardar
Keyword(s):  
Curcuma Longa ◽  
Folk Medicine ◽  
Herbal Medicines ◽  
Crocus Sativus ◽  
Medical Community ◽  
Complementary Medicines ◽  
Severe Impairment ◽  
Joint Disorder ◽  
Rosmarinus Officinalis L ◽  
English Articles

Rheumatoid arthritis (RA) is a chronic inflammatory and debilitating joint disorder that causes severe impairment and reduces the quality of life. The available synthetic medicines used as standard therapy for RA have numerous side effects that can compromise their therapeutic outcomes. Thus, the demand for alternative and complementary medicines is increasing. A search of English articles in PubMed, Scopus, Google Scholar, and Web of Science databases was carried out on probable mechanisms of action of herbs with the antirheumatic property. Herbal medicines stated in folk medicine face acceptance concerns by the medical community because of the lack of scientific documents regarding their physio-pharmacological mechanisms. This chapter aims to review the possible antirheumatic effects of various herbs, including Rosmarinus officinalis L., Curcuma longa, and Crocus sativus, their related mechanisms, and preclinical applications, in order to recall the therapeutic properties of herbal medicine. However, more clinical trials are required to confirm the safety and efficacy of these antirheumatic herbal medicines.

Persian herbal medicine in functional dyspepsia: a systematic review article.

2020 ◽  
Vol 17 ◽  
Author(s):  
Maryam Azimi ◽  
Mohammad Javad Zahedi
Keyword(s):  
Clinical Trials ◽  
Herbal Medicine ◽  
Functional Dyspepsia ◽  
Nigella Sativa ◽  
Curcuma Longa ◽  
Crocus Sativus ◽  
Herbal Remedies ◽  
Asparagus Racemosus ◽  
Gastric Accommodation ◽  
Cynara Scolymus

Introduction: According to Rome IV, functional dyspepsia is diagnosed with presence of dyspepsia in the absence of organic or metabolic causes. FD caused by several factors such as impaired gastric accommodation and hypersensitivity to gastric distention. Several studies have reported effectiveness of herbal medicine on FD. This article, thus, reviews Persian herbal medicine in FD. Method: Electronic databases including Pubmed, Scopus, Cochrain, Embase, Web of science and Ovid were searched so as to find clinical articles related to dyspepsia and herbal medicine by July 2019. Our search strategies were traditional medicine, complementary and alternative medicine, herb, plant, and dyspepsia. We excluded all articles except Persian clinical trials. Results: We found 34 clinical trials with 15 herbs and 4 compound herbal remedies like Asparagus racemosus, Brassica oleracea, Cynara scolymus, Ocimum basilicum, Mentha longifolia, Mentha pulegium, Mentha piperata, Pimpinella anisum, Nigella sativa, Mastic gum, Curcuma longa, Pistatio atlantica, Glycyrrhiza glabra, Solanum tuberosum and Zingiber officinale and compound remedies of Rosa damascene & Crocus sativus, Trachyspermum copticom & Apium graveolence, Carum carvi & Mentha pipperata, Gingiber officinalis & Cynara scolymus are effective in functional dyspepsia. Conclusion: Many people use herbal and traditional remedies for treatment of disorders such as gastrointestinal disordersو , especially in Asian countries. Several studies reported the efficacy of herbal medicine in functional dyspepsia. Although their mechanisms are not fully understood, it seems they can modulate GI motility and improve symptoms of FD.

Antiviral and Immunity-modulating Natural Herbs in the Prevention of COVID-19

2021 ◽  
pp. 81-94
Author(s):  
Sonali S Gadge
Keyword(s):  
Immune System ◽  
Medicinal Plants ◽  
Nigella Sativa ◽  
Curcuma Longa ◽  
Antiviral Drug ◽  
Herbal Medicines ◽  
Echinacea Purpurea ◽  
Black Pepper ◽  
Tinospora Cordifolia ◽  
Ocimum Sanctum

The COVID-19 has spread all over the world and there is no single drug or medicine for the prevention and the treatment of this deadly disease. One can get prevention from this disease by boosting the immune system. Persons with weak immune system e.g. children, elder patients or patients with preexisting diseases affect rapidly due to coronavirus. This novel coronavirus attacks mainly on the person immunity. For the centuries the herbal medicinal plants have many beneficial effects against deadly viruses. Herbal medicines provide a rich resource for new antiviral drug development. These natural agents interact with the life cycle of virus such as virus entry, replication, assembly and release. In this review, the importance, immunomodulator, antiviral and pharmacological activities of some medicinal plants, namely, Allium Sativum, Zingiber Officinalis, Cinnamomum zeylanicum, Curcuma longa, Ocimum sanctum, Glycyrrhiza glabra, Ginseng, Black pepper, Emblica officinalis, Withania somnifera, Tinospora cordifolia, Echinacea purpurea, Azadirachta indica, Piper betel, Eugenia caryophyllata, Cinchona calisaya, Nigella sativa, Cuminum cyminum are highlighted. These medicinal plants have many phytoconstituents like alkaloids, glycosides, terpenoids, flavonoids, lactones, polysaccharides, volatile oils, tannins, resins, etc which are helpful for boosting immunity and will help in the prevention and in the management of COVID-19. Several types of research attempted to use herbal medicines against COVID-19.

scholarly journals Herbal mouthwash based on Libidibia ferrea: microbiological control, sensory characteristics, sedimentation, pH and density

2015 ◽  
Vol 44 (2) ◽  
pp. 118-124 ◽  
Author(s):  
Gisely Naura Venâncio ◽  
Isis Costa Rodrigues ◽  
Tatiane Pereira de Souza ◽  
Raquel de Oliveira Marreiro ◽  
Maria Fulgência Costa Lima Bandeira ◽  
...  
Keyword(s):  
Folk Medicine ◽  
Herbal Medicines ◽  
Mouth Diseases ◽  
Number Of Microorganisms ◽  
Microbiological Control ◽  
Density Values ◽  
Density Evaluation ◽  
Therapeutic Properties ◽  
And Staphylococcus Aureus

Introduction Phytotherapy is the study of herbal medicines and their applicability to cure diseases in general, being a therapeutic method which can be used for the prevention and treatment of mouth diseases. Among the herbal studied, the Libidibia ferrea, known as jucá or ironwood, is widely used in folk medicine by presenting anti-inflammatory, analgesic, antimicrobial and antipyretic therapeutic properties. Objective To evaluate in vitro pharmacological stability of the Libidibia ferrea extract’s mouthwash (INPA - 228 022). Material and method It was held the mouthwash microbiological control by determining the total number of microorganisms and Salmonella sp, Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus; stability characteristics (color, odor, brightness and consistency), sedimentation test (centrifuge), the pH measurement (pH meter) and density evaluation (pycnometer) were analyzed. Result The mouthwash showed to be absent from microorganisms and no changes were observed in the organoleptics and sedimentation characteristics. The average pH values were 6.21, 6.15 and 5.85 at 0, 30 and 60 days, respectively, and 1.029, 1.033 and 1.035 g/ mL density values, respectively, without interfering with the final characteristic of the formulation. Conclusion The mouthwash presented pharmacological stability and quality conditions.

scholarly journals Review on Antityrosinase Activity of Some Indian Medicinal Plants and their Phytoconstituents

2020 ◽  
Vol 10 (5-s) ◽  
pp. 199-204
Author(s):  
Ruchi Gupta ◽  
Rajiv Saxena ◽  
Archana Patidar ◽  
Yashu Chourasiya ◽  
Neelesh Malviya
Keyword(s):  
Mammalian Cells ◽  
Curcuma Longa ◽  
Skin Surface ◽  
Crocus Sativus ◽  
Enzymatic Reactions ◽  
Tyrosinase Inhibitor ◽  
Melanin Biosynthesis ◽  
Hemidesmus Indicus ◽  
Color Changes ◽  
Antityrosinase Activity

Tyrosinase (polyphenolic oxidase) is a multifunctional and copper containing enzyme. Tyrosinase is an enzyme which is responsible for melanin biosynthesis which is responsible for color of the skin. Melanin is synthesised in melanocyte cells by melanogenesis process.  Melanogenesis protects skin surface from harmful ultraviolet radiations. Melanin is mainly synthesized in plants, micro organisms and mammalian cells. Melanin pigment is responsible for hyperpigmentation and hypopigmentation. When melanin is present in very less amount it causes local vitiligo and posttraumatic hypopigmentation. When melanin is present in very less amount it causes local vitiligo and posttraumatic hypopigmentation. Abnormal amount of melanin deposit in the specific sites of skin causes abnormal skin colored patches like solar lentigos, chloasma, freckles, post inflammatory hyperpigmentation etc. Tyrosinase is also responsible for color changes in fruits due to enzymatic reactions. Tyrosinase inhibitor compounds are used in cosmetics, food, agriculture science and also used in remedy for imbalance in pigmentations. Some Indian herbal plants and agents like Aloe barbedensis, Crocus sativus, Curcuma longa, Camellia sinensis, Glycyrrhiza glabra, Glycine max, Nelumbo nucifera, Hemidesmus indicus, Vitis Vinifera, Broussonetia papyrifera, resorcinol, arbutin, kojic acid, hydroquinone and ascorbic acid have antityrosinase enzymatic activity. So these plants and inhibitory agents are used in cosmetic industries due to their tyrosinase inhibitory effects or antityrosinase activity or antihyperpigmentation effects. Keywords: Anti-hyperpimentation, Tyrosinase Inhibitor, Melanin, Herbal drugs.

scholarly journals Pharmaceutical Analysis of An Anti-Diabetic Formulation: Kimshukatvagadi Ghana Capsule

2021 ◽  
Vol 12 (2) ◽  
pp. 247-250
Author(s):  
Garima Singh ◽  
Shailesh V Deshpande ◽  
Rinjin G Krishna
Keyword(s):  
High Performance ◽  
Curcuma Longa ◽  
Large Population ◽  
Herbal Medicines ◽  
Chemical Components ◽  
Butea Monosperma ◽  
Solvent Systems ◽  
Strychnos Potatorum ◽  
Layer Chromatography ◽  
Salacia Reticulata

Ayurveda is one of the oldest and holistic science. Herbal medicines have a long therapeutic history; serving many of the health needs of large population of the world. However, the quality control and assurance remains as a challenge due to the high discrepancy of chemical components involved. In Ayurvedic texts, several formulations have been mentioned in Prameha (Diabetes Mellitus). Kimshukatvagadi is one such formulation mentioned in Sahasrayoga Vati Prakarana adhyaya. It contains Palash (Butea monosperma Lam.), Haridra (Curcuma longa L.), Amalaki (Emblica officinalis L.), Kataka (Strychnos potatorum L.f.), Vairi (Salacia reticulata Wight). Kimshukatvagadi Vati was converted into Ghana to increase its potency and then it was sealed into Capsule for increasing the shelf life, making it easy to dispense, dose fixation etc. Kimshukatvagadi Ghana Capsule was subjected to organoleptic analysis, phytochemical and qualitative analysis to detect the presence of various functional groups, and to high performance thin layer chromatography (HPTLC) examination by optimizing the solvent systems.

Plant-derived medicines for neuropathies: a comprehensive review of clinical evidence

2019 ◽  
Vol 30 (6) ◽  
pp. 671-684 ◽  
Author(s):  
Farnaz Ebrahimi ◽  
Mohammad Hosein Farzaei ◽  
Roodabeh Bahramsoltani ◽  
Mojtaba Heydari ◽  
Kiana Naderinia ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Viral Infections ◽  
Cannabis Sativa ◽  
Linseed Oil ◽  
Curcuma Longa ◽  
Herbal Medicines ◽  
Cochrane Library ◽  
Congenital Diseases ◽  
Beneficial Effects ◽  
Long Time

AbstractNeuropathy is defined as the damage to the peripheral or central nervous system accompanied by pain, numbness, or muscle weakness, which can be due to congenital diseases or environmental factors such as diabetes, trauma, or viral infections. As current treatments are not sufficiently able to control the disease, studies focusing on the identification and discovery of new therapeutic agents are necessary. Natural products have been used for a long time for the management of different neurological problems including neuropathies. The aim of the present study is to review the current clinical data on the beneficial effects of medicinal plants in neuropathy. Electronic databases including PubMed, Scopus, and Cochrane Library were searched with the keywords ‘neuropathy’ in the title/abstract and ‘plant’ or ‘extract’ or ‘herb’ in the whole text from inception until August 2017. From a total of 3679 papers, 22 studies were finally included. Medicinal plants were evaluated clinically in several types of neuropathy, including diabetic neuropathy, chemotherapy-induced peripheral neuropathy, carpal tunnel syndrome, and HIV-associated neuropathy. Some studies reported the improvement in pain, nerve function, nerve conduction velocity, and quality of life.Cannabis sativa(hemp),Linum usitatissimum(linseed oil), capsaicin, and a polyherbal Japanese formulation called Goshajinkigan had the most evidence regarding their clinical efficacy. Other investigated herbal medicines in neuropathy, such asMatricaria chamomilla(chamomile),Curcuma longa(turmeric), andCitrullus colocynthis(colocynth), had only one clinical trial. Thus, future studies are necessary to confirm the safety and efficacy of such natural medicines as a complementary or alternative treatment for neuropathy.

scholarly journals Spices and herbs as immune enhancers and anti-inflammatory agents: A review

2021 ◽  
Vol 14 ◽  
Author(s):  
Andrew Garnier ◽  
Fereidoon Shahidi
Keyword(s):  
Curcuma Longa ◽  
Zingiber Officinale ◽  
Black Pepper ◽  
Crocus Sativus ◽  
Piper Nigrum ◽  
Syzygium Aromaticum ◽  
Pelargonium Sidoides ◽  
Devil’S Claw ◽  
Anti Inflammatory ◽  
Pimenta Dioica

Spices and herbs have been used in traditional medicine for centuries, with research starting to accumulate on their beneficial properties. Of these properties, the immune-enhancing and anti-inflammatory capabilities of many spices and herbs have led to promising results. The current review article aims to explore the current research of several spices and herbs as immune-enhancers and anti-inflammatory agents. The spices and herbs examined are African potato (Hypoxis hemerocallidea), allspice (Pimenta dioica), basil (Ocimum basilicum), black pepper (Piper nigrum), chili powders (Capsicum species), clove (Syzygium aromaticum), Devil’s claw (Harpagophytem procumbens), fenugreek (Trigonella foenum-graecum), ginger (Zingiber officinale), lavender (Lavandula angustifolia), oregano (Origanum vulgare), rooibos (Aspalathus linearis), rosemary/sage (Salvia rosmarinus/officinalis), saffron (Crocus sativus), South African geranium (Pelargonium sidoides), and turmeric (Curcuma longa). All the spices and herbs exhibited immune-enhancing or immunomodulatory and anti-inflammatory capabilities through various processes. Rooibos and oregano had the most contradictory results, with some studies finding pro-inflammatory properties, especially at high doses regarding oregano. Turmeric had the most extensive research with positive results.

scholarly journals Therapeutic Potential of Saffron Crocus (Crocus sativus L.)

2016 ◽  
Vol 4 (12) ◽  
pp. 1240 ◽  
Author(s):  
Zeliha Selamoglu ◽  
Senay Ozgen
Keyword(s):  
Medicinal Plants ◽  
Scarlet Fever ◽  
Therapeutic Potential ◽  
Heart Diseases ◽  
Folk Medicine ◽  
Crocus Sativus ◽  
Folk Remedy ◽  
Herbal Plants ◽  
Crocus Sativus L

Herbal plants are using for folk medicine since immemorial times. Hippocrates who is the father of medicine, refer to 400 medicinal plants and advised ‘‘let food be your medicine and let medicine be your food’’. Most of plants are using today for medicine. It is still acceptable today that prevention is more important than treatment. Saffron was utilized in folk remedy against scarlet fever, smallpox, colds, asthma, eye and heart diseases, tumours, and cancer.

scholarly journals Curcuma Longa (Turmeric): A Condiment of Great Therapeutic Value Tested with the Ayurveda up to the Modern Medicine

2021 ◽  
Vol 5 (1) ◽  
pp. 1-8
Author(s):  
Shah NC
Keyword(s):  
Chemical Constituents ◽  
Curcuma Longa ◽  
Folk Medicine ◽  
Modern Medicine ◽  
Folk Culture ◽  
Important Ingredient ◽  
Important Chemical ◽  
Traditional Remedies ◽  
Therapeutic Value ◽  
Therapeutic Compounds

Turmeric is associated and is a part of Indian's culture: it is an important ingredient in curry dishes; it is also used in many religious observances, as a cosmetic, a dye, and it enters in the composition of many traditional remedies. This paper deals with its botany, its earliest reference in 'Atharva Veda', its uses in folk medicine, folk cosmetics, as a folk condiment, folk dye, its folk-chemistry, used in folk culture, and etymology and philology of 36 Sanskrit names, its important chemical constituents and its pharmacodynamics, its biopiracy and finally, the conclusion and discussions with a suggestion that when drug or its therapeutic compounds have been pharmacologically and therapeutically tested then why it is not being used in the modern medicine as a post-operative drug.

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