scholarly journals Concurrent and Predictive Validity of the Depression Anxiety Stress Scale-21 in Multiple Sclerosis: A Cross-Sectional Study with Controlling the Confounding Factors

2020 ◽  
Vol 22 (3) ◽  
Author(s):  
Ghasem Salehpoor ◽  
Habib Hadianfard

Background: The assessment of psychological symptoms in multiple sclerosis (MS) patients could play a key role in identifying the adverse effects of the disease. Objectives: This study aimed to assess the concurrent and predictive validity of the Depression Anxiety Stress Scale-21 (DASS-21) in patients with MS. Methods: In a cross‐sectional study in 2010, 162 patients were selected by a consecutive method. Depression Anxiety Stress Scales-21 (DASS-21), the Fatigue Severity Scale (FSS), and the Short-Form Health Survey (SF-36) Questionnaire were used in this study. Data were analyzed using Pearson’s correlation coefficient and multivariate hierarchical regression analyses. Results: The findings of the present study revealed that DASS-21 subscales have a strong correlation with the constructs of fatigue and SF-36 components (r = 0.29 to -0.71; P < 0.01). In addition, each of the symptoms of depression, anxiety, and stress independently predicted a significant proportion of the variance in the scores on fatigue and eight aspects of health (P ≤ 0.006) even after controlling the confounding factors. Conclusions: The present study has highlighted the concurrent and predictive validity of DASS-21 in MS. Thus, this study suggests that therapeutic interventions for reducing psychological symptoms can lead to an improvement in different dimensions of health.

2020 ◽  
Vol 6 (2) ◽  
pp. 95
Author(s):  
Agus Hendra ◽  
Bella Risma Heryanti ◽  
Agni Laili Perdani

Stress adalah masalah kesehatan yang akan menjadi epidemik global pada abad ke-21. Mahasiswa keperawatan adalah kelompok masyarakat yang rentan akan stress dan dipicu oleh faktor akademik, klinik dan lingkungan. Dinamika perubahan belajar dan perbedaan proses akademik dari sekolah ke perguruan tinggi dan hal tersebut menjadi sumber utama stress pada mahasiswa baru. Tujuan penelitian ini adalah untuk menggambarkan tingkatan depresi, kecemasan, dan stress pada mahasiswa junior keperawatan.. Penelitian ini adalah cross-sectional study yang dilakukan di salah satu institusi keperawatan di Indonesia pada bulan Desember-January 2019. Teknik sampling yang digunakan adalah convenience sampling dengan Instrumen DASS (Depression Anxiety Stress Scale). Pengambilan data menggunakan online questionnaire form dan teknik analisa univariate data dengan SPSS Version 25. Rata-rata usia pada tahap remaja 19.13 (SD±0.59), 82% perempuan dan 80.8% tinggal bersama orang tua kandung (p < 0.000). Rata-rata tingkat depresi 16.24 (SD±9.71), kecemasan 13.71 (SD±0.59) atau berada pada kategori sedang dan rata-rata tingkat stress adalah 12.49 (SD±10.18) (p < 0.000). Total 25 (32.1%), 28 (35.9%) dan 52 (66.7%) responden pada depresi, kecemasan dan stress adalah normal. Depresi - stress berada pada rata-rata tertinggi 1.14 (SD ± 0.89) dan terendah adalah kecemasan - stress (SD±0.68). Identifikasi data awal tingkat stress, depresi dan kecemasan pada mahasiswa junior dibutuhkan oleh institusi sebagai upaya dalam melakukan manajemen stress. Tindakan kolaboratif bersama dapat diupayakan oleh berbagai pihak meliputi pelatihan teknik relaksasi, pengenalan strategi koping efektif ataupun penyediaan sumber-sumber yang dapat digunakan oleh mahasiswa sebagai upaya institusi dalam menciptakan proses akademik dan praktik klinis yang baik. 


2021 ◽  
Vol 21 (1) ◽  
pp. 15-19
Author(s):  
Ahmad Ghiffari ◽  
Syahrul Muhammad ◽  
M. Avif Ababil

The level of stress in each education programs differ between medical students and other scholars. Students should able to cope to normalize their stress. The study aims to determine the relationship between the duration of reading the Qur'an with the level of stress on students. The study design was a cross-sectional study, with a simple random sampling. The collecting data technique was using the Depression Anxiety Stress Scale (DASS) questionnaires and duration questionnaires followed by the chi-square analysis. The respondents are 90 medical students of Universitas Muhammadiyah Palembang. The results showed that the duration of reading the Qur'an among students is poor, and the moderate duration is correlated with a good stress level (p=0,002). Concluded that there is a relation to the duration of reading The Qur'an with the level of stress in medical students.


2021 ◽  
pp. 9-14
Author(s):  
Gabriela Vanesa Espasa ◽  
Luciana González Lucero ◽  
Yessika Jackeline Soria Curi ◽  
Susana Marcela Mazza ◽  
María Lilia Leguizamón ◽  
...  

Introduction: sexual dysfunction is the alteration in one or several phases of sexual activity. It can culminate in frustration, pain and a decrease in the frequency of sexual intercourse. Objectives: determine the frequency of sexual dysfunction and analyze associated factors in patients with SLE. Materials and methods: a descriptive cross-sectional study was conducted. We included patients with SLE, between 18 and 50 years of age, Secondary Sjogren’s syndrome, menopause, severe depression and illiterate patients were excluded. Demographic and disease-related variables were studied. The Depression Anxiety Stress Scale (DASS-21), and the Female Sexual Function Index (FSFI) were applied. Results: sixty women with SLE and 63 controls were evaluated. The prevalence of SD in SLE was 71.7% and there were significant differences in all domains of sexual function. The total FSFI score in patients with SLE was lower when compared to controls. According to the DASS-21 scale, stress, anxiety and depression were observed in at least half of lupus women, however no association was found between these variables and SD. Conclusions: the prevalence of SD in patients with SLE was high. Depression, Anxiety, and Stress were not determinants in the presence of SD.


BMJ Open ◽  
2017 ◽  
Vol 7 (10) ◽  
pp. e018023 ◽  
Author(s):  
Blánaid Hayes ◽  
Lucia Prihodova ◽  
Gillian Walsh ◽  
Frank Doyle ◽  
Sally Doherty

ObjectivesTo measure levels of psychological distress, psychological wellbeing and self-stigma in hospital doctors in Ireland.DesignNational cross-sectional study of randomised sample of hospital doctors. Participants provided sociodemographic data (age, sex, marital status), work grade (consultant, higher/basic specialist trainee), specialty and work hours and completed well-being questionnaires (the Depression Anxiety Stress Scale, WHO Well-being Index, General Health Questionnaire) and single-item scales on self-rated health and self-stigma.SettingIrish publicly funded hospitals and residential institutions.Participants1749 doctors (response rate of 55%). All hospital specialties were represented except radiology.ResultsHalf of participants were men (50.5%). Mean hours worked per week were 57 hours. Over half (52%) rated their health as very good/excellent, while 50.5% reported positive subjective well-being (WHO-5). Over a third (35%) experienced psychological distress (General Health Questionnaire 12). Severe/extremely severe symptoms of depression, anxiety and stress were evident in 7.2%, 6.1% and 9.5% of participants (Depression, Anxiety, Stress Scale 21). Symptoms of distress, depression, anxiety and stress were significantly higher and levels of well-being were significantly lower in trainees compared with consultants, and this was not accounted for by differences in sociodemographic variables. Self-stigma was present in 68.4%.ConclusionsThe work hours of doctors working in Irish hospitals were in excess of European Working Time Directive’s requirements. Just over half of hospital doctors in Ireland had positive well-being. Compared with international evidence, they had higher levels of psychological distress but slightly lower symptoms of depression and anxiety. Two-thirds of respondents reported self-stigma, which is likely to be a barrier to accessing care. These findings have implications for the design of support services for doctors, for discussions on quality of patient care and for future research.


Author(s):  
Zeinab E. Afifi ◽  
Rania I. Shehata ◽  
Asmaa F. El Sayed ◽  
El Sayed M. Hammad ◽  
Marwa R. Salem

Abstract Background Nutrition was claimed to be a factor in MS causation, course, complications, and management. Several studies were conducted to assess the nutritional status of MS patients; however, few studies were conducted to assess this problem in Egypt. Therefore, the purpose of the current study was to assess the nutritional status of a sample of MS patients. Methods The researchers conducted an exploratory cross-sectional study among 76 relapsing-remitting MS (RRMS) patients attending Kasr Alainy Multiple Sclerosis Unit (KAMSU) from October 2018 to January 2019 to assess the nutritional status of a sample of MS patients. Data were collected using a structured interview questionnaire including an inquiry about the socioeconomic status, and nutritional status using anthropometric measurements, patient-generated subjective global assessment (PG-SGA), semi-quantitative food frequency questionnaires (SQFFQ), and hemoglobin level measurement. Assessment of fatigue was done using the Modified Fatigue Impact Scale 5-items version. Results The mean age of the study participants was 30 ± 6 years. The disease duration ranged from 2 to 264 months. Malnutrition was prevalent among 67.1% (27.6 % overweight, 36.8% obese, and 2.6% underweight). Half of the investigated patients were anemic. According to the PG-SGA, more than half of the studied patients (53.9%) were classified as moderately or suspected malnourished. The unhealthy dietary habits such as taking only a few meals, junk food intake and skipping breakfast were observed in considerable proportions of the group. The SQFFQ revealed overconsumption of energy and fat, and less than acceptable consumption of dietary fibers by most of the studied patients. Conclusions Overweight, obesity, anemia, and unhealthy dietary habits were prevalent among the RRMS patients attending the KAMSU. Nutrition care service is extremely needed for this group of patients.


2020 ◽  
Vol 32 (1) ◽  
Author(s):  
Nearmeen M. Rashad ◽  
Marwa G. Amer ◽  
Waleed M. Reda Ashour ◽  
Hassan M. Hassanin

Abstract Background Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system with varied clinical features. Disease-modifying drugs (DMDs) of MS associated with different types of thyroiditis. In this cross-sectional study, we aimed to assess the prevalence of thyroid dysfunction in MS and to investigate the association between DMDs and the risk of thyroiditis in MS. A cross-sectional study included 100 patients with relapsing-remitting multiple sclerosis (RRMS) in relapse, and the diagnosed was according to revised McDonald’s criteria 2010. Results Our results revealed that the prevalence of thyroiditis was 40%; autoimmune (34%) and infective (6%) among patients with RRMS in relapse and cerebellar symptoms were significantly higher in patients with thyroiditis compared to patients without thyroiditis. Regarding the association between DMDs and thyroiditis, the prevalence of patients treated with interferon-beta-1b was higher in MS patients with thyroiditis compared to MS patients without thyroiditis. However, the prevalence of patients treated with interferon-beta-1a was lower in MS patients with thyroiditis compared to MS patients without thyroiditis. In addition, we found CMV infection was more common in patients treated by interferon beta-1b and candida infection was common in patients treated by fingolimod. Conclusions Thyroiditis is commonly observed in patients with RRMS in relapse and higher prevalence of patients treated with interferon-beta-1b which is commonly associated with thyroiditis and CMV infection; however, candida thyroid infection was common in MS patients treated by fingolimod.


Pain Medicine ◽  
2021 ◽  
Author(s):  
Michal Rivel ◽  
Anat Achiron ◽  
Mark Dolev ◽  
Yael Stern ◽  
Gaby Zeilig ◽  
...  

Abstract Objective About a third of patients with multiple sclerosis (MS) suffer from chronic and excruciating central neuropathic pain (CNP). The mechanism underlying CNP in MS is not clear, since previous studies are scarce and their results are inconsistent. Our aim was to determine whether CNP in MS is associated with impairment of the spinothalamic-thalamocortical pathways (STTCs) and/or increased excitability of the pain system. Design Cross sectional study Setting General hospital Subjects 47 MS patients with CNP, 42 MS patients without CNP, and 32 healthy controls. Methods Sensory testing included the measurement of temperature, pain, and touch thresholds and the thermal grill illusion (TGI) for evaluating STTCs function, and hyperpathia and allodynia as indicators of hyperexcitability. CNP was characterized using interviews and questionnaires. Results The CNP group had higher cold and warm thresholds (p &lt; 0.01), as well as higher TGI perception thresholds (p &lt; 0.05), especially in painful body regions compared to controls, whereas touch and pain thresholds values were normal. The CNP group also had a significantly greater prevalence of hyperpathia and allodynia. Regression analysis revealed that whereas presence of CNP was associated with a higher cold threshold, CNP intensity, and the number of painful body regions were associated with allodynia and hyperpathia, respectively. Conclusions CNP in MS is characterized by a specific impairment of STTC function; the innocuous thermal pathways, and by pain hyperexcitability. Whereas CNP presence is associated with STTC impairment, its severity and extent are associated with pain hyperexcitability. Interventions that reduce excitability level may therefore mitigate CNP severity.


Nutrients ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 2380
Author(s):  
Eduardo Sánchez-Sánchez ◽  
Jara Díaz-Jimenez ◽  
Ignacio Rosety ◽  
Maria José M. Alférez ◽  
Antonio Jesús Díaz ◽  
...  

The COVID-19 pandemic has impacted the mental health of people worldwide. An increase in perceived stress can lead to unhealthy behaviors such as increased food consumption. The aim of this study was to find the level of perceived stress and its relationship with increased food consumption during the “third wave” of the COVID-19 pandemic in Spain. This was a cross-sectional study that employed anonline self-reported frequency of consumption questionnaire and the Perceived Stress Scale-10. A total of 637 subjects participated and 83.6% of respondents had moderate or high stress—more prevalent in the female and young respondents. Moreover, 36.1% of respondents reported that they had increased the frequency of consumption of some foods, mainly nuts, snacks, and jellybeans, along with coffee, tea, cocoa, and soft drinks. Eating between meals was more pronounced in those with high stress (65.1%) than in those with moderate stress (40.4%) and low stress (20.2%). Furthermore, the respondents with high stress reported greater weight gain. Thus, the results show that the level of perceived stress during the ‘third wave’ of this pandemic increased food consumption.


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