scholarly journals A cross sectional study on Salmonella in apparently healthy sheep and goats slaughtered at Elfora and Luna export abattoirs, Ethiopia

2017 ◽  
Vol 11 (13) ◽  
pp. 530-536 ◽  
Author(s):  
Kuma Feyisa ◽  
Lakew Matios ◽  
Koran Tafesse ◽  
Olani Abebe ◽  
Tamiru Mekdes ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Sheep And Goats ◽  
Healthy Sheep ◽  
Apparently Healthy

scholarly journals Dysfunctional Adiposity Index as a Useful Clinical Tool for Early Identification of Adipose Tissue Morpho-Functional Abnormalities and Cardiometabolic Disorders in Apparently Healthy Subjects

2020 ◽  
Author(s):  
Juan Reyes-Barrera ◽  
Victor H. Sainz-Escárrega ◽  
Aida X. Medina-Urritia ◽  
Esteban Jorge-Galarza ◽  
Horacio Osorio-Alonso ◽  
...  
Keyword(s):  
Risk Factors ◽  
Adipose Tissue ◽  
Clinical Practice ◽  
Early Identification ◽  
Healthy Subjects ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Adiposity Index ◽  
Apparently Healthy

Abstract BackgroundCompared to body mass index (BMI), waist circumference (WC), and adiposity measurements, adipose tissue morpho-functionality evaluations are more consistent predictors of cardiometabolic abnormalities. However, these evaluations require determination of adipokines and other non-routine biochemical parameters, which is not feasible in clinical practice. The present study establishes dysfunctional adiposity index (DAI) as a simple, accessible, and reliable marker of early adipocytes morpho-functional abnormalities and cardiometabolic diseases.MethodsTo establish the DAI constant parameters, 340 subjects (134 males and 206 females) without cardiovascular risk factors were selected from a cross-sectional study. Then, DAI was calculated in 36 healthy subjects who underwent subcutaneous adipose tissue biopsy, for whom adipocytes number and size, body composition, circulating adipokines, glucose, insulin, and lipids were also determined. The correlation of DAI with adipocyte morphology (size/number of adipocytes) and functionality (adiponectin/leptin ratio) was analyzed. The receiver operating characteristic curve was used to define the optimal DAI cut-off point to identify metabolic abnormalities. Finally, the independent association of DAI with cardiometabolic abnormalities was determined in 1418 subjects from the cross-sectional study through multivariate analyses.ResultsThe constant parameters to calculate the DAI were [WC/[22.79+[2.68*BMI]]]*[triglycerides (TG, mmol/L)/1.37]*[1.19/high density lipoprotein-cholesterol (HDL-C, mmol/L)] for males, and [WC/[24.02+[2.37*BMI]]]*[TG(mmol/L)/1.32]*[1.43/HDL-C(mmol/L)] for females. In subjects underwent biopsy, DAI correlated with adipocytes mean area (r=0.358; p=0.032), adipocyte number (r=-0.381; p=0.024), adiponectin/leptin ratio (r=-0.483; p=0.003), and systemic inflammation markers. Compared to BMI, WC, and visceral fat, DAI was the only determination associated with insulin resistance (area under the curve: 0.743; p = 0.017). In the cross-sectional study, DAI ≥1.065 was independently associated with diabetes (OR: 1.96; 95%CI: 1.36-2.84), non-alcoholic fatty liver disease (OR: 2.57; 95%CI: 1.98-3.33), subclinical atherosclerosis (OR: 1.74; 95%CI: 1.02-2.94), and hypertension (OR: 1.44; 95%CI: 1.10-1.88).ConclusionsThe present study establishes the constant parameters to calculate the DAI and highlights that a DAI ≥ 1.065 is associated with early cardiometabolic abnormalities independently of adiposity and other risk factors. Since DAI is calculated using accessible parameters routinely used in the clinic, this indicator can be easily incorporated in clinical practice for the early identification of adipose tissue abnormalities in apparently healthy subjects.

scholarly journals Community based hematological reference intervals among apparently healthy adolescents aged 12-17 years in Mekelle city, Tigrai, northern Ethiopia: A cross sectional study

PLoS ONE ◽  
2020 ◽  
Vol 15 (9) ◽  
pp. e0234106
Author(s):  
Hagos Haileslasie ◽  
Aster Tsegaye ◽  
Gebreyohanes Teklehaymanot ◽  
Getachew Belay ◽  
Gebreslassie Gebremariam ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Reference Intervals ◽  
Northern Ethiopia ◽  
Sectional Study ◽  
Community Based ◽  
Cross Sectional ◽  
Mekelle City ◽  
Apparently Healthy

Associations between white blood cells count and obesity in apparently healthy young adults

2020 ◽  
Vol 50 (6) ◽  
pp. 1013-1019
Author(s):  
Fatemeh Ghannadiasl
Keyword(s):  
Young Adults ◽  
Cardiovascular Diseases ◽  
Blood Cells ◽  
White Blood Cells ◽  
Cross Sectional Study ◽  
The Body ◽  
Sectional Study ◽  
Cross Sectional ◽  
Content Type ◽  
Apparently Healthy

Purpose The elevated white blood cells (WBCs) count has been reported to be a predictor of cardiovascular diseases, diabetes, hypertension and metabolic syndrome. This study aims to determine the associations between WBCs count and obesity in apparently healthy young adults. Design/methodology/approach In this cross-sectional study, the authors evaluated the body mass index (BMI) in 392 apparently healthy young adults of both sexes. The WBCs count was measured using standard counter techniques. The inclusion criteria were the agreement to participate in the study, between 18 and 25 years of age, lack of self-reported diseases such as cardiovascular diseases, hypertension, kidney and infectious diseases. Findings According to the BMI classification, underweight and overweight or obesity were observed in 14.58 and 11.48 per cent of young adults, respectively. The mean WBC was 6.5 ± 1.5 (×10³ cells/µL). Higher values of WBCs were found in women than in men (p = 0.02). The young adults with higher BMI had a higher WBCs count. There was a positive correlation between WBCs count and weight and BMI (r = 0.19 and r = 0.22, p < 0.001, respectively). Research limitations/implications This research was a cross-sectional study. Future studies are suggested using longitudinal studies to examine more relationships between obesity and WBCs count in apparently healthy young adults. Practical implications The results of this study provide evidence for weight management in this age group to reduce diseases associated with increased WBCs count. Originality/value The WBCs count was related to increasing levels of BMI per cent 2 C even in the normal range.

scholarly journals Estimación de la tasa de filtración glomerular en personas con y sin síndrome metabólico

2016 ◽  
Vol 3 (1) ◽  
pp. 22
Author(s):  
María E Lizardo ◽  
María del Pilar Navarro ◽  
Marqjuly Camacho ◽  
Melvimar Alejandra Magallanes-Hernández ◽  
Rubsy Gabriela Pacheco-Gutiérrez ◽  
...  
Keyword(s):  
Abdominal Obesity ◽  
Cross Sectional Study ◽  
Strongly Correlated ◽  
Healthy Individuals ◽  
Sectional Study ◽  
Cross Sectional ◽  
Glomerular Function ◽  
Síndrome Metabólico ◽  
System Risk ◽  
Apparently Healthy

Introduction: Metabolic syndrome (MS) is an independent risk factor, which affects the development of chronic kidney disease, so the glomerular filtration rate (GFR) as an indicator of glomerular function in patients with and without MS who attended the outpatient clinic “los Grillitos, sector Caña de Azucar”. Materials and Methods: A comparative, correlational, cross-sectional study was conducted in a non-probability sample of convenience consisting of 60 patients with MS diagnosed according to the criteria Panel ATP III, and 60 apparently healthy individuals, whom the GFR was determined by the Cockcroft-Gault as well as clinical and biochemical parameters for the diagnosis of MS. Results: Out of the total patients evaluated, 37 (30.7%) showed alterations that put them in grades G2 and G3 system risk stratification of CKD, of these 18 and 19 corresponded to patients with and without MS respectively. Glomerular Hyperfiltration (> 120 mil / min) it was found in both groups 28 (46.7%) and 24 (40%) cases of patients with and without MS respectively. The glomerular function was strongly correlated with abdominal obesity and high levels of stress arterial. As for the number of criteria and its relationship to the level of kidney damage present, not a firm to increase the latter with respect to the first (p=0.385) trend was observed. Conclusion: The change in the glomerular function is not directly related to the MS but with its components, specifically abdominal obesity and hypertension.

Antioxidant Vitamin Status (A, E, C, and Beta-Carotene) in European Adolescents - The HELENA Study

2011 ◽  
Vol 81 (4) ◽  
pp. 245-255 ◽  
Author(s):  
Christina Breidenassel ◽  
Jara Valtueña ◽  
Marcela González-Gross ◽  
Jasmin Benser ◽  
Andre Spinneker ◽  
...  
Keyword(s):  
Vitamin C ◽  
Reference Values ◽  
Representative Sample ◽  
Beta Carotene ◽  
Cross Sectional Study ◽  
Antioxidant Vitamins ◽  
Alpha Tocopherol ◽  
Sectional Study ◽  
Cross Sectional ◽  
Apparently Healthy

Background: An adequate nutritional status of antioxidant vitamins (vitamins A, C, E) and b-carotene is essential especially during childhood and adolescence, because of their important roles in cell growth and development. Currently, there are no physiological reference values for blood concentration of these vitamins and b-carotene in apparently healthy European adolescents. The aim of the current study was to obtain reliable and comparable data of antioxidant vitamins and b-carotene in a cross-sectional study, within HELENA (Healthy Lifestyle in Europe by Nutrition in Adolescence), which was conducted in a representative sample of adolescents from ten European cities. Material and Methods: From a subsample of 1,054 adolescents (males= 501) of the HELENA Cross Sectional Study with an age range of 12.5 to 17.49 years, fasting blood samples were taken and analyzed for vitamins A, E, C, and b-carotene status. As specific reference values for adolescents are missing, percentile distribution by age and sex is given. Results: Mean concentrations were the following: Retinol: 356.4 ± 107.9 cm/mL; alpha-tocopherol: 9.9 ± 2.1 microg/mL; vitamin C: 10.3 ± 3.3 mg/L; and b-carotene: 245.6 ± 169.6 cm/mL. Females showed higher alpha-tocopherol and vitamin C values compared with males and 17-year-old boys had higher retinol levels than the same-aged girls (p = 0.018). Retinol serum concentrations increased significantly according to age in both gender, but girls had also significantly increasing b-carotene levels by age. Conclusions: For the first time, concentrations of antioxidant vitamins and pro-vitamin beta-carotene have been obtained in a representative sample of apparently healthy European adolescents. These data can contribute to the establishment of reference ranges in adolescents.

A descriptive cross-sectional study of Platelets count in apparently healthy Eritrean blood donors attending the National Blood Transfusion Center, Asmara, Eritrea

2020 ◽  
Vol 3 (1) ◽  
pp. 14-17
Author(s):  
Faris Mohamed Awad Abdon ◽  
◽  
Elias Teages Adgoy ◽  
Nahom Yacob Berhane ◽  
Senet Awolker Ibrahim ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Blood Donors ◽  
Cross Sectional Study ◽  
Blood Bank ◽  
Reference Ranges ◽  
Sectional Study ◽  
Cross Sectional ◽  
Normal Ranges ◽  
The Difference ◽  
Apparently Healthy

Background: Platelets are an important constituent of blood. Safety measures of blood transfusion are important for optimum health environment. To the knowledge of the researchers, there is no study that was conducted concerning Platelets count in apparently healthy Eritrean blood donors. Therefore, this study will help in establishing the reference ranges of Platelets count in them. Objectives: To measure the serum platelets levels and mean platelets volume in apparently healthy Eritrean blood donors attending the national blood bank of Eritrea. Study design: Descriptive crosssectional study. Materials and methods: 610 Blood donors were incorporated in the study. 4 ml of venous blood was collected into K3EDTA tubes (Becton Dickinson, Plymouth, UK) from all of the participants of the study. Blood samples collected into the (EDTA)-tubes were examined for Platelets count and mean platelet volume. Results: The overall mean of platelets count was 267.145 ± (65.915) ×109 /L, The median and mode of values were both 266.3 thousands/mm3. The mean platelet count for the females was 296.122 thousands /mm3, and for males was 252.477 ×109 /L, and the statistic difference between them was significant. The statistic mean of MPV for males was 8.763 fl, and for females was 8.717, and the difference between the two means also considered insignificant. Conclusion: This descriptive cross sectional study was performed in the National Blood bank in Asmara where platelets levels and mean platelets volume were measured for 610 healthy blood donors. The results were found to be within reference normal ranges. The difference between the males and females results was statistically significant

scholarly journals Plasma Aminothiol Profile and Some of Its Determinants in Apparently Healthy Azorean Subjects

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Ana Lima ◽  
Rita Ferin ◽  
José Baptista ◽  
M. Leonor Pavão
Keyword(s):  
Cross Sectional Study ◽  
Vitamin B ◽  
Sectional Study ◽  
Cross Sectional ◽  
Azores Archipelago ◽  
Reference Concentration ◽  
B Vitamin ◽  
Design And Methods ◽  
Conventional Risk Factors ◽  
Apparently Healthy

Objectives. To evaluate the plasma aminothiol profile (PAP) and serum gamma-glutamyltransferase (GGT) activity, as well as plasma folate, vitamin B12, and vitamin B6 concentrations, in 326 apparently healthy subjects from the Azores archipelago (Portugal). Also eventual relationships of PAP with conventional risk factors for atherosclerosis were investigated, aiming at the finding of early blood markers of the disease. Design and Methods. This was an observational cross-sectional study, where participants were split into two groups: one with a normal and another with an altered PAP (at least one aminothiol out of its reference concentration range). Results. About 76% of subjects had an altered PAP, mainly due to low glutathione levels (<1.5 μmol/L), mostly associated with normal GGT activity. Prevalence of hyperhomocysteinemia was 10%, where only 33% had some B-vitamin deficiency. The risk for atherosclerosis was more evidenced in subjects exhibiting both deficient GSH concentration and increased serum GGT activity. Conclusions. An altered PAP, namely, when caused by low GSH levels in the absence of alterations in the Hcy, or Cys, or Cys-Gly concentrations and in serum GGT activity, might reveal a subclinical stage of atherogenesis and should be explored as a potential early marker of atherosclerosis.

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