Comparative cytomorphometric analysis of oral mucosa in patients with Diabetes, patients with associated oral habits but with apparently normal mucosa and Control group

Objectives. Depression is associated with diabetes mellitus and affects treatment goals negatively. We aimed to determine the prevalence of depression and identify its socio-demographic or clinical correlates among patients with diabetes mellitus attending an out-patient clinic in Nigeria.Methods. Two hundred consecutively recruited diabetes patients (index group) were compared with a similar number of apparently healthy controls in a cross-sectional survey. In both groups, in addition to obtaining socio-demographic details, depression was diagnosed using the Schedule for the Clinical Assessment in Neuropsychiatry (SCAN), while the Beck Depression Inventory (BDI) was used to assess depression symptom severity. Results. Sixty (30%) diabetes patients met a SCAN diagnosis for clinical depression, compared with 19 (9.5%) in the control group. Having a smaller income and more children were significantly correlated with higher depression symptoms on the BDI.Conclusion. Depression is highly co-morbid with diabetes mellitus. The care of individuals with diabetes mellitus should include the screening and possible treatment for depression in order to achieve and sustain treatment goals.

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NOSOGENIC DEPRESSION IN PATIENTS WITH PATHOLOGY OF THE MUCOUS ORAL CAVITY

The actual problems in dentistry ◽

10.18481/2077-7566-2019-15-4-50-54 ◽

2020 ◽

Vol 15 (4) ◽

pp. 50-54 ◽

Cited By ~ 2

Author(s):

Karen Karakov ◽

Tatyana Vlasova ◽

Artur Oganyan ◽

Araksia Khachaturyan ◽

Svetlana Karakova ◽

...

Keyword(s):

Comparative Analysis ◽

Oral Cavity ◽

Treatment Regimen ◽

Oral Mucosa ◽

New Technologies ◽

Well Being ◽

Diagnostic Methods ◽

Control Group ◽

Traditional Treatment ◽

And Control

Importance. Despite the improvement of diagnostic methods and the introduction of new technologies in the treatment of pathology of the oral mucosa, it is difficult to achieve stable remission, since 70 % of cases are based on somatic and bodily suffering factors. The article presents data from a comparative analysis of the use of the traditional treatment regimen for patients with pathology of the oral cavity and the inclusion of the latest generation of antipsychotics in the treatment regimen. It was established that, when applied, a tendency towards normalization of psychological and autonomic status was observed. The inclusion of anxiolytics and antioxidants in the complex of general therapy for patients with pathology of the oral mucosa contributed to a more pronounced positive dynamics of achieving and prolonging the phase of remission. Objectives — to evaluate the effectiveness of introducing drugs of the latest generation of antipsychotics into the traditional treatment regimen for patients with pathology of the oral cavity. Methodology. Under our supervision, there were 30 patients aged 40 to 60 years with a diagnosis of pathology of the oral mucosa and pathology of the periodontium. All examined were divided into 2 groups: the main (15 people) and control (15 people). Results. Clinical well-being, manifested in a subjective decrease in pain in the tongue, feelings of rawness, tingling, numbness, awkwardness, in the tongue, was noted already at the 5th visit in 67 % of patients of the main group, while in the control group in 17 % of patients. Conclusions. The inclusion of anxiolytics and antioxidants in the complex of general therapy for patients with pathology of the oral mucosa contributed to a more pronounced positive dynamics of achieving and prolonging the phase of remission. Our data allow us to implement this treatment regimen in practical healthcare.

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EFFECT OF FAMILY PSYCHOEDUCATION ON CAREGIVER SUPPORT IN THE TREATMENT OF PATIENTS WITH TYPE II DIABETES MELLITUS

Belitung Nursing Journal ◽

10.33546/bnj.342 ◽

2018 ◽

Vol 4 (1) ◽

pp. 112-119

Author(s):

Andika Siswoaribowo ◽

Mateus Sakundarno ◽

Muhammad Mu’in

Keyword(s):

Diabetes Mellitus ◽

T Test ◽

Control Group ◽

P Value ◽

Family Psychoeducation ◽

Control Group Design ◽

Caregiver Support ◽

Significant Difference ◽

Patients With Diabetes ◽

And Control

Background: Diabetes Mellitus is a chronic disease that requires treatment for long periods of time so it can cause physical and psychological problems for sufferers and families (caregiver). Caregiver's role is expected to provide support for people with diabetes mellitus. Family psychoeducation is a strategy that can be applied for caregiver in overcoming problems that arise during the treatment of patients with diabetes mellitus.Objective: This study aims to determine the effect of family psychoeducation on caregiver support in the treatment of patients with diabetes mellitus type II.Methods: This research used a quasi experiment with pre-test post-test control group design. A total of 46 caregivers and patients with diabetes mellitus were recruited puposively, with 23 respondents assigned in the experiment and control group. Caregiver support scale was used to measure caregiver support, and Hensarling Diabetes Family Support Scale (HDFSS) for measuring perception of patients toward the treatment of caregiver. Data were analyzed using paired t-test and independent t-test. Results: Findings showed there was an increase of caregiver knowledge from 5.39 to 9.09 and an improvement of caregiver treatment from 40.30 to 67.04 after given family psychoeducation. There was a significant difference of caregiver support in the experimental and control group with p-value <0.001 (<0.05).Conclusion: Family psychoeducation can increase caregiver support in the treatment of diabetes mellitus patients. The intervention can be one of nurses interventions in the empowerment of family in improving the treatment of chronic diseases, particularly in diabetes mellitus.

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Khat Chewing and Smoking Effect on Oral Mucosa: A Clinical Study

Acta Medica (Hradec Kralove Czech Republic) ◽

10.14712/18059694.2016.122 ◽

2009 ◽

Vol 52 (4) ◽

pp. 155-158 ◽

Cited By ~ 8

Author(s):

Essam Halboub ◽

Essam Dhaifullah ◽

Mahmoud Abdulhuq

Keyword(s):

Clinical Study ◽

Oral Mucosa ◽

Smoking Habit ◽

Clinical Findings ◽

Control Group ◽

Control Groups ◽

Catha Edulis ◽

Khat Chewing ◽

Clinical Relationship ◽

And Control

Khat (Catha Edulis Forskal) is widely cultivated in Yemen and East of Africa. The habit of chewing tender leaves and twigs of khat is deep-rooted in Yemen. Our study investigates the chronic khat chewing and smoking effect on oral mucosa. The sample (n=79) consists of two main groups, khat chewers (n=54) and control groups (n=25). Khat chewers group is divided into 4 subgroups according to duration of khat chewing and smoking habit. The control group is divided into 2 subgroups according to smoking habit. Whitening with mild corrugation, frictional keratosis and frictional keratosis with mild or sever corrugation were the clinical findings. One hundred percent of clinical findings were present on buccal mucosa of chewing side of both smokers and non-smokers whatever the duration of khat chewing period. On the vestibular and mucobuccal fold mucosa, (100 % and 73.3 %) and (60 % and 43.7 %) of the khat chewers group had clinical findings on chewing side of smokers and non-smokers according to khat chewing duration respectively. There was clinical relationship between these lesions and khat chewing, but not smoking. Khat chewing causes oral white lesions on the chewing side and it is found that smoking, clinically, does not exacerbate such lesions.

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Cytomorphometric and nucleomorphometeric analysis in patients with malignant lesion, patients with associated habits but with apparently normal mucosa and control group

Research Journal of Pharmacy and Technology ◽

10.5958/0974-360x.2016.00342.5 ◽

2016 ◽

Vol 9 (10) ◽

pp. 1699

Author(s):

L Harsha ◽

S. Gheena ◽

Khushali. K. Shah

Keyword(s):

Malignant Lesion ◽

Normal Mucosa ◽

Control Group ◽

And Control

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Evaluation of a mobile phone telemonitoring system for glycaemic control in patients with diabetes

Journal of Telemedicine and Telecare ◽

10.1258/jtt.2009.003006 ◽

2009 ◽

Vol 15 (3) ◽

pp. 125-128 ◽

Cited By ~ 123

Author(s):

Robert SH Istepanian ◽

Karima Zitouni ◽

Diane Harry ◽

Niva Moutosammy ◽

Ala Sungoor ◽

...

Keyword(s):

Mobile Phone ◽

Controlled Trial ◽

Group Analysis ◽

Intervention Group ◽

Control Group ◽

Web Based ◽

Technical Problems ◽

Intention To Treat ◽

Patients With Diabetes ◽

And Control

We conducted a randomized controlled trial using mobile health technology in an ethnically diverse sample of 137 patients with complicated diabetes. Patients in the intervention group ( n = 72) were trained to measure their blood glucose with a sensor which transmitted the readings to a mobile phone via a Bluetooth wireless link. Clinicians were then able to examine and respond to the readings which were viewed with a web-based application. Patients in the control arm of the study ( n = 65) did not transmit their readings and received care with their usual doctor in the outpatient and/or primary care setting. The mean follow-up period was 9 months in each group. The default rate was higher in the patients in the intervention arm due to technical problems. In an intention-to-treat analysis there were no differences in HbA1c between the intervention and control groups. In a sub-group analysis of the patients who completed the study, the telemonitoring group had a lower HbA1c than those in the control group: 7.76% and 8.40%, respectively ( P = 0.06).

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Renoprotective effects of canagliflozin, a sodium glucose cotransporter 2 inhibitor, in type 2 diabetes patients with chronic kidney disease: A randomized open-label prospective trial

Diabetes and Vascular Disease Research ◽

10.1177/1479164118782872 ◽

2018 ◽

Vol 15 (5) ◽

pp. 469-472 ◽

Cited By ~ 10

Author(s):

Hiroyuki Takashima ◽

Yoshinori Yoshida ◽

Chinami Nagura ◽

Tetsuya Furukawa ◽

Ritsukou Tei ◽

...

Keyword(s):

Type 2 Diabetes ◽

Chronic Kidney Disease ◽

Kidney Disease ◽

Adverse Events ◽

Prospective Trial ◽

Control Group ◽

Open Label ◽

And Control ◽

Diabetes Patients

Background: To evaluate the renoprotective effects of canagliflozin, we assessed the albuminuria-lowering effect in Japanese type 2 diabetes patients with chronic kidney disease (CKD). Methods: In this prospective, open-label, parallel-group study, type 2 diabetes patients with CKD were randomized to receive either oral canagliflozin (100 mg/day) or usual care (control group) for 52 weeks. Endpoints included changes in urinary albumin-to-creatinine ratio (UACR), other urinary biomarkers, laboratory parameters, and adverse events. Results: Both groups included 20 patients in the analysis. Mean changes in UACR was −83 (−266 to −31) mg/gCr and 27 (−11 to 131) mg/gCr, in the canagliflozin and control groups, respectively ( p = 0.004). Urinary liver-type free acid binding protein, N-acetyl-β-d-glucosaminidase, and β2-microglobulin levels were also significantly decreased in the canagliflozin group, but not in the control group. Mean change in estimated glomerular filtration rate at the end of the study was 0.7 and −3.4 mL/min/1.73 m2 in the canagliflozin and control group, respectively ( p = 0.024). Canagliflozin treatment led to improvement of glycaemic control and reduction in body weight, blood pressure, and liver transaminase. There were no adverse events associated with canagliflozin. Conclusion: Canagliflozin was associated with slower progression of kidney disease and reduction in albuminuria and tubulointerstitial markers in diabetes patients with CKD.

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Diabetes Mellitus in Pancreatic Cancer Patients in the Czech Republic: Sex Differences

Experimental Diabetes Research ◽

10.1155/2012/414893 ◽

2012 ◽

Vol 2012 ◽

pp. 1-5 ◽

Cited By ~ 6

Author(s):

Jan Trna ◽

Petr Dítĕ ◽

Arona Adamcová ◽

Brianna J. Crawford ◽

Markéta Hermanová

Keyword(s):

Diabetes Mellitus ◽

Pancreatic Cancer ◽

Cancer Patients ◽

Control Group ◽

Cancer Group ◽

Time Period ◽

Patients With Diabetes ◽

And Control ◽

Prevalence Of Diabetes Mellitus ◽

New Onset

Aims. The prevalence of diabetes mellitus in pancreatic cancer patients and control subjects was compared.Methods. Retrospective evaluation of 182 pancreatic cancer patients and 135 controls. The presence of diabetes was evaluated and the time period between the diagnosis of diabetes and pancreatic cancer was assessed. A subanalysis based on patient sex was conducted.Results. Diabetes mellitus was present in 64 patients (35.2%) in pancreatic cancer group and in 27 patients (20.0%) in control group (χ2=8.709;P=0.003). In 18 patients (28.1% of diabetic pancreatic cancer patients) diabetes was new-onset. Diabetes was new-onset in 23.3% of females compared to 38.1% of males (χ2=1.537;P=0.215). The overall prevalence of diabetes was significantly higher among female pancreatic cancer patients (25% versus 43.9%;χ2=7.070,P=0.008), while diabetes prevalence was equally represented in the control group patients (22.1% versus 17.2%;χ2=0.484,P=0.487).Conclusion. The prevalence of diabetes mellitus in study group of pancreatic cancer patients was significantly higher when compared to control group. Pancreatic cancer patients with diabetes were predominantly females, while diabetes was equally prevalent among sexes in the control group. Therefore, patient sex may play important role in the risk stratification.

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Model Self Management Education (SME) Dalam Meningkatkan Kemampuan Deteksi Dini Hipoglikemia Pada Diabetesi Di RSUD Dr Moewardi Surakarta

Interest : Jurnal Ilmu Kesehatan ◽

10.37341/interest.v5i2.55 ◽

2016 ◽

Vol 5 (2) ◽

Author(s):

Siti Lestari ◽

Tri Sunaryo

Keyword(s):

Early Detection ◽

Management Education ◽

Self Management ◽

Control Group ◽

P Value ◽

Patients With Diabetes ◽

Long Time ◽

Quasi Experimental ◽

And Control ◽

The Impact

Abstract: Self-Management Education, Hypoglycemia. Diabetes Mellitus is a metabolic disease that needs attention and care for a long time in order to prevent complications. People with DM must have good knowledge, skill, and behavior so they can manage their life by themselves. Research showed that 50–80%, people with DM have not enough knowledge to manage their disease. Through the self-management, people with diabetes can improve their competence in early detection of hypoglycemia so it would increase the quality of life and reduce the risk of developing complications. The purpose of this study was to investigate the impact of diabetes self-management education toward early detection of hypoglycemia among patients with diabetes. A quasi-experimental pre and post design with a control group was used to investigate the impact of using education on self-management. The participants were 40 that divided into intervention and control group. Purposive sampling was used to take the samples. T-Test was used to analyze the data. The competence of diabetes in early detection of hypoglycemia was an increase, from 6,1 with SD 13.7 to 71,7 with SD 19.2. Then, the model of Self Management education influenced the competence of people with diabetes in the early detection of hypoglycemia, P value 0,011 (α = 0,05). The findings demonstrate that self-management education could improve the competence of diabetes in the early detection of hypoglycemia.

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Relationship between diabetes self-care practices and control of periodontal disease among type2 diabetes patients in Bangladesh

PLoS ONE ◽

10.1371/journal.pone.0249011 ◽

2021 ◽

Vol 16 (4) ◽

pp. e0249011

Author(s):

S. M. Mahmudul Hasan ◽

Mosiur Rahman ◽

Keiko Nakamura ◽

Yuri Tashiro ◽

Ayano Miyashita ◽

...

Keyword(s):

Type 2 Diabetes ◽

Periodontal Disease ◽

Oral Hygiene ◽

Periodontal Diseases ◽

Self Care ◽

Hygiene Practices ◽

Patients With Diabetes ◽

And Control ◽

Diabetes Patients

Introduction The prevalence of periodontal disease is high in diabetes patients worldwide, including Bangladesh. Although associations of periodontal disease outcomes and clinical determinants of diabetes have been investigated, few studies have reported on the relationship between periodontal diseases outcomes with modifiable factors, such as self-care and oral hygiene practices, in patients with diabetes. Moreover, in order to develop targeted strategies, it is also important to estimate their aggregated contribution separately from that of the established sociodemographic and diabetics related clinical determinates. Therefore, this study was performed to elucidate 1) the relationship of diabetes patients’ self-care and oral hygiene practices to periodontal disease and 2) the relative contributions of selected factors to periodontal disease outcome in type 2 diabetes patients. Methods The data were obtained from the baseline survey of a multicentre, prospective cohort study. A total of 379 adult patients with type 2 diabetes from three diabetic centres in Dhaka, Rajshahi and Barishal, received periodontal examinations using the community periodontal index (CPI) probe, glycated haemoglobin examination, other clinical examinations, and structured questionnaires. Multiple logistics regression analyses were performed to assess the associations between selected factors and prevalence of any periodontal disease and its severity. Results More than half of the participants were female (53.8%) and 66.8% of the total participants was 21–50 years old. The prevalence of any (CPI code 2+3+4; 75.7%) and severe form (CPI code 4; 35.1%) of periodontal disease were high in type 2 diabetes patients. In multivariate analysis, the odds of periodontal disease increased with unfavourable glycaemic control indicated by HbA1c ≥ 7%, and decreased by 64%, 85% and 92% with adherence to recommended diet, physical activity, and oral hygiene practices, respectively. Diabetes self-care practice explained the highest proportion of the variance (13.9%) followed by oral hygiene practices (10.9%) by modelling any periodontal disease versus no disease. Variables of diabetes conditions and oral hygiene practices explained 10.9% and 7.3% of the variance by modelling severe (CPI code 4) or moderate (CPI code 3) forms of periodontal disease versus mild form of periodontal disease. Findings also conferred that while poor diabetes control had an individually adverse association with any form of periodontal diseases and its severity, the risk of diseases was moderated by oral hygiene practices. Conclusions This study suggested that, in addition to diabetes-related clinical determinants, self-care practices, and oral hygiene practices must be taken into consideration for prevention and control of periodontal disease in patients with diabetes.

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