scholarly journals Insulin som trickster: Grænsearbejde i hverdagen med type 2 diabetes

Kulturstudier ◽  
2012 ◽  
Vol 2 (2) ◽  
pp. 45
Author(s):  
Aske Juul Lassen

<span style="font-family: MeliorLTCE; font-size: x-small;"><span style="font-family: MeliorLTCE; font-size: x-small;"><p>The article focuses on the role of insulin in the everyday life of the type 2 diabetic. The diagnosis of type 2 diabetes is not merely the establishment of a chronic disease, it also alters the patient’s conception of his own body and his everyday life. For many patients, the diagnosis is their first encounter with the interiors of their bodies. It is attempted to regulate the diabetes by a number of practices; in the article, this is viewed as a bio-medical disciplinization, which deals with the body and life as objects. The biomedicine conquers the diabetic body and becomes part of the diabetic’s everyday life. Thereby, the body is problematized as a natural and delimited category. The limits of the body are broken down by the recurring penetration of the skin, when the blood sugar is measured or the insulin injected. Insulin is analysed as a trickster figure which exerts a boundary work on the body, plays with its categories and inverts the relations between poison and medicine, freedom and constraint, artificiality and naturalness, security and risk. Everyday life is changed and future put into perspective by the trickster, which at the same time makes both everyday life and the future possible by its blood sugar reducing properties.</p></span></span>

2021 ◽  
pp. 187-188
Author(s):  
Ajay Jain ◽  
Debina sarkar ◽  
G.G. Kaushik ◽  
Ankita Sharma

Background: Type-2 diabetes mellitus (T2DM) is a progressive and chronic disease characterized by both β-cell dysfunction and increased insulin resistance. Diabetes mellitus is now considered a giant killer disease of the 21st century with its vicious prongs in the South-East Asian countries, specially India, which is rightly said to be the ''Diabetes Capital'' of the world. Vitamin D has important effects on insulin action, and may impact on a number of pathways which may be of importance in the development of type 2 diabetes mellitus. Materials & Methods: In this study 62 Type-2 diabetic patients, 62 healthy controls were enrolled. Biochemical analytes measured were Serum glucose (Fasting Blood Sugar & Post Prandial Blood Sugar), Glycosylated Haemoglobin, Serum Vitamin-D. Results: The mean Serum Vitamin-D in Type-2 diabetic subjects were (16.3 ±3.0) while in healthy subjects(controls) the values were (39.3±5.2) respectively. These values were found to be statistically highly signicant(p<0.001). Conclusion: Serum Vitamin-D levels were decreased in Type 2 diabetic subjects as compared to the values in healthy subjects(controls).


2020 ◽  
Vol 3 (3) ◽  
pp. 150
Author(s):  
Bayu Brahmantia ◽  
Miftahul Falah ◽  
Lilis Lismayanti ◽  
Vina Erviana

Diabetes Mellitus is a metabolic disorder disease characterized by a rise of blood sugar due to a decrease of insulin by the pancreas. The role of the family in caring for the patient with type 2 diabetes mellitus is crucial in treatment. this study was aimed to know the ability of family in caring. a purposive sampling method was applied in this research. a total of 31 respondents were selected. the results showed that the majority of family's ability to recognize as a problem was good with 16 people ( 51,6 % ), in taking decisions for treatment was positive as much as 19 people (61.3%), in treatment of type 2 Diabetes Mellitus patients were positive 25 people (80,6%), in modifying the environment for Treatment was negative  18 people (58.1%). therefore, Health education for the family related to modifying the environment for treatment was required to recover the patient.


Author(s):  
Srishti Sonwani ◽  
Sutakshee Sonwani

Background: Previous studies have reported the presence of diabetes ketoacidosis in patients of type 2 diabetes mellitus (T2DM). India reported that up to 30% of hospitalized DKA cases result in inpatient death. Aims and objectives of the study was to study the role of HbA1c and duration of diabetes in outcome of patients of diabetic ketoacidosis in type 2 diabetes mellitus.Methods: Hundred T2DM patients having DKA admitted in the Department of Medicine, Gandhi Medical College and Hamidia Hospital, Bhopal, were included. Data on demography (age, sex and diabetes duration, random blood sugar (RBS) and glycated hemoglobin (HbA1c) were recorded for each patients. Outcome was also recorded and compared with duration of diabetes and HbA1c level.Results: DKA was more common in age group of51-55 years (21%) with mean age of 56.10±10.40 years. Male preponderance was observed. Mean duration of diabetes, hemoglobin, random blood sugar (RBS) and HbA1c were 7.28±3.81 years, 9.8±1.42 gm%, 351.72±22.32 mg/dl, and 7.14±0.10 respectively. Mortality was higher among the patients with longer duration of diabetes (23.1%; p=0.012) and higher HbA1c (25%, p>0.05).Conclusions: Duration of diabetes play a significant role in deciding mortality in T2DM patients with DKA however HbA1c has no role in that.


2021 ◽  
Vol 2 (2) ◽  
pp. 51-57
Author(s):  
Fitria Silvia ◽  
Mappeaty Nyorong ◽  
Miskah Afriany ◽  
Lucia Lastiur

Diabetes exercises are physical exercises designed according to age and physical status and are part of the treatment of diabetes mellitus. When a person does physical exercise in the muscles of the body, the heart system and blood circulation and breathing are activated. Therefore, the body's metabolism, fluid and electrolyte balance and acid base must adjust. Muscles will use free fatty acids and glucose as a source of energy or energy. When physical exercise begins glucose originating from muscle-muscled glycogen when physical exercise starts being used as a source of energy. Assessing the effect of the implementation of prolanis exercise activities on reducing blood sugar levels in patients with Type 2 Diabetes Mellitus in Puskesmas Padangmatinggi in 2019. This type of research is quantitative with a quasi-experimental design that designs using one group pretest-posttest, when this study was conducted in January-April year 2020. The population in this study were all patients with diabetes mellitus who follow prolanis gymnastics in Padangmatinggipuskesmas with purposive sampling technique, namely the determination of the sample by specifying specific characteristics consisting of 15 intervention / experimental groups and 15 control groups 15 people The results showed that there was an effect of the application of prolanic exercise activities to reduce blood sugar levels in patients with type 2 diabetes at Padangmatingi Public Health Center in Padangsidimpuan with a P-Value of 0.007, and there were differences in blood sugar levels in the intervention and control groups with a P. Value of 0,000.


2021 ◽  
Vol 09 (1) ◽  
pp. 239-242
Author(s):  
Bansode Sheetal

Ayurveda is the science of living being. It begins with right lifestyle including daily and seasonal health regime designed for each individual based upon their nature, constitution, environment and life circumstances. Madhumeha is the subtype of Prameha. Due to resemblance of the feature of Madhumeha with that of DM explained in modern medicine, it is correlated with DM. According to WHO approximately 220 million people worldwide have type 2 diabetes mellitus. It is widely recognized that stress may have negative effects on health and that patients with type 2 diabetes may be at an increased risk. Yoga is an ancient Indian psychological and physical exercise regime and a number of controlled studies exist on the effectiveness of yoga on diabetes mellitus. Yogic practices strengthen and increase the tone of weak muscles and help with conscious control over autonomic function of the body. So, the present study on the role of Yogaabhyas as a lifestyle modification in Madhumeha. Keywords: Madhumeha, type 2 diabetes, asana in diabetes


Author(s):  
Martin Luck

‘Appetite, fat, and obesity’ considers the role of insulin in the body’s fat storage process. In the condition diabetes mellitus, the sugar level in the blood rises uncontrollably so the kidneys cannot stop it leaking into the urine. Type 1 diabetes is an autoimmune disease in which a person’s immune system attacks the insulin-secreting β-cells of the pancreas. The only effective treatment is to inject the missing insulin. Type 2 diabetes is considered more of a lifestyle disease. But what exactly is the connection between obesity and poorly regulated blood glucose? The body has more hormones capable of responding to energy shortage than to energy abundance, which may be why keeping control of body weight can be difficult. The hormones affecting appetite are also discussed.


Author(s):  
GOZIF MOHAMMED N OMAR ◽  
FADEL YOUSIF AL-ARABI ◽  
MANSOUR ABDULNABI H MEHDI ◽  
MADHUKAR M FAWADE

Objectives: This study is to investigate the effect of oral Vitamins combined (A, C, and E) with metformin on the levels of fasting blood sugar (FBS), postprandial blood sugar (PPBS), hemoglobin (HbA1c), total cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL), and low-density lipoprotein (LDL) in Type 2 diabetic patients. Methods: A total of 32 patients with Type 2 diabetes were divided randomly into A and B groups, i.e., 16 per each group. Group A received metformin only twice a day while Group B received one tablet of Antox and metformin twice a day for 3 months. FBS, PPBS, HbA1c, TC, TG, LDL, and HDL were measured before and after the dose, and the results were analyzed statistically. Results: A significant decreases in FBS, PPBS, HbA1c, TC, TG, and LDL whereas results showed increasing significance in HDL level that seen in the patients of Group B which received Antox and metformin compared to the group which received metformin only. In conclusion, the results indicate that daily consumption of supplementary vitamins with metformin leads to improving blood glucose and lipids in patients with Type 2 diabetes and reducing the risk of complications. Hence, the dose can be used combined Vitamins A, C, and E with metformin in the treatment of Type 2 diabetes by maintaining good glycemic control.


2007 ◽  
Vol 113 (4) ◽  
pp. 183-193 ◽  
Author(s):  
Xiao C. Li ◽  
Jia L. Zhuo

Pancreatic bi-hormones insulin and glucagon are the Yin and Yang in the regulation of glucose metabolism and homoeostasis. Insulin is synthesized primarily by pancreatic β-cells and is released in response to an increase in blood glucose levels (hyperglycaemia). By contrast, glucagon is synthesized by pancreatic α-cells and is released in response to a decrease in blood glucose (hypoglycaemia). The principal role of glucagon is to counter the actions of insulin on blood glucose homoeostasis, but it also has diverse non-hyperglycaemic actions. Although Type 1 diabetes is caused by insulin deficiency (insulin-dependent) and can be corrected by insulin replacement, Type 2 diabetes is a multifactorial disease and its treatment is not dependent on insulin therapy alone. Type 2 diabetes in humans is characterized by increased insulin resistance, increased fasting blood glucose, impaired glucose tolerance and the development of glomerular hyperfiltration and microalbuminuria, ultimately leading to diabetic nephropathy and end-stage renal disease. Clinical studies have suggested that an inappropriate increase in hyperglycaemic glucagon (hyperglucagonaemia) over hypoglycaemic insulin (not insulin deficiency until advanced stages) plays an important role in the pathogenesis of Type 2 diabetes. However, for decades, research efforts and resources have been devoted overwhelmingly to studying the role of insulin and insulin-replacement therapy. By contrast, the implication of glucagon and its receptor signalling in the development of Type 2 diabetic metabolic syndromes and end-organ injury has received little attention. The aim of this review is to examine the evidence as to whether glucagon and its receptor signalling play any role(s) in the pathogenesis of Type 2 diabetic renal injury, and to explore whether targeting glucagon receptor signalling remains only a theoretical antidiabetic strategy in Type 2 diabetes or may realize its promise in the future.


2013 ◽  
Vol 154 (5) ◽  
pp. 178-186 ◽  
Author(s):  
József Pauer ◽  
Attila Fék ◽  
Barbara Buday ◽  
Botond Literáti-Nagy ◽  
Péter Pach ◽  
...  

Introduction: The recognition of prediabetic patients with the genetic risk of type 2 diabetes is very important as prediabetes is the last stage when manifestation of diabetes could be prevented by life style modification or drug intervention. This suggests the need for diagnostic processes to trace the risk of patients in time. Aims: The authors looked for metabolic differences between age and BMI in adjusted healthy men with or without first degree type 2 diabetic relatives. Methods: The study included 73 healthy men (21 with and 52 without) first-degree relatives with type 2 diabetes. Results: Total body and muscle tissue glucose utilization, glucose tolerance did not differ between the two groups, but free fatty acid levels were not suppressed by glucose load in subjects with diabetic relatives. In addition the body fat content, leptin and IL-6 levels were higher, while adiponectin and the free fatty acid/adiponectin ratio were significantly lover in healthy men with diabetic relatives. In this group HDL cholesterol, and the large buoyant LDL fraction were lower whereas the high density LDL – small molecular lipid fraction was higher than those measured in subjects without diabetic relatives. Conclusions: These data suggest that deteriorations of insulin sensitivity and glucose tolerance is preceded by disturbances of fatty acid metabolism. The observed alteration in free fatty acid/adiponectin ratio, and/or the absence of free fatty acid suppression during glucose tolerance tests could be a screening tool for diabetes risk among men. Orv. Hetil., 2013, 154, 178–186.


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