The promise of probiotics in dentistry

2013 ◽  
Vol 9 (1) ◽  
Author(s):  
Binu Neelikad Sugunan ◽  
Resmi Chandrahasan Nair
Keyword(s):  
Candida Albicans ◽  
Immune System ◽  
Oral Health ◽  
Scientific Evidence ◽  
Data Sources ◽  
Probiotic Bacteria ◽  
Direct Inhibition ◽  
Study Selection ◽  
Probiotic Lactobacilli ◽  
Micro Organisms

Objectives: The aim of this review is to examine the potential mechanisms of probiotic bacteria in the oral cavity and to summarize the observed effects of probiotics with regard to oral health. Additionally, safety concerns and future aspects are briefly considered. Data sources: Studies suggest that probiotics may function not only by direct inhibition of—or enhanced competition with—pathogenic micro-organisms, but also by more subtle mechanisms including modulation of the mucosal immune system. Clinical studies reporting the anticariogenic effects of probiotics and their use in the treatment of periodontal disease and in the treatment of halitosis and Candida albicans have been identified. Study selection: The studies focus on probiotic Lactobacilli and Bifidobacteria genera that are most used in various probiotic products. Conclusions: Although direct recommendations for the use of oral probiotics cannot yet be given, scientific evidence so far indicates that probiotic therapy may be a reality in dentistry in the future.

scholarly journals Probiotics and Oral Health

2010 ◽  
Vol 04 (03) ◽  
pp. 348-355 ◽  
Author(s):  
Anna Haukioja
Keyword(s):  
Oral Health ◽  
Oral Cavity ◽  
Health Benefits ◽  
Probiotic Bacteria ◽  
Gut Health ◽  
Gastrointestinal Infections ◽  
Viable Bacteria ◽  
Clinical Interest ◽  
Probiotic Lactobacilli

The number of products containing probiotics, viable bacteria with proven health benefits, entering the market is increasing. Traditionally, probiotics have been associated with gut health, and most clinical interest has been focused on their use for prevention or treatment of gastrointestinal infections and diseases; however, during the last decade several investigators have also suggested the use of probiotics for oral health purposes. The aim of this review is to examine potential mechanisms of probiotic bacteria in the oral cavity and summarize observed effects of probiotics with respect to oral health. The review focuses on probiotic lactobacilli and bifidobacteria, genera that are most used in various probiotic products. (Eur J Dent 2010;4:348-355)

Adaptation factors of the probiotic Lactobacillus rhamnosus GG

2010 ◽  
Vol 1 (4) ◽  
pp. 335-342 ◽  
Author(s):  
S. Lebeer ◽  
J. Vanderleyden ◽  
S. De Keersmaecker
Keyword(s):  
Current Knowledge ◽  
Lactobacillus Rhamnosus ◽  
Health Benefit ◽  
Probiotic Strain ◽  
Probiotic Bacteria ◽  
Host Immune System ◽  
Lactobacillus Rhamnosus Gg ◽  
Probiotic Lactobacilli ◽  
Micro Organisms ◽  
Performance Adaptation

Probiotic bacteria are administered as live micro-organisms to provide a health benefit to the host. Knowledge on adaptation factors that promote the survival and persistence of probiotics in the intestine is key to understand and improve their ecological and probiotic performance. Adaptation factors include adhesins, molecules conferring stress tolerance and nutritional versatility, antimicrobial products against competing microbes, and factors promoting resistance against the host immune system. Here, we present an overview of the current knowledge on adaptation factors of probiotic lactobacilli, with focus on the prototypical and widely documented probiotic strain Lactobacillus rhamnosus GG.

Influence of the Intestinal Microbiota on Diabetes Management

2020 ◽  
Vol 21 (15) ◽  
pp. 1603-1615
Author(s):  
Eva Alvarez-Vieites ◽  
Arora López-Santamarina ◽  
José M. Miranda ◽  
Alicia del Carmen Mondragón ◽  
Alexandre Lamas ◽  
...  
Keyword(s):  
Immune System ◽  
Intestinal Microbiota ◽  
Diabetes Management ◽  
Scientific Evidence ◽  
Focused Attention ◽  
Economic Implications ◽  
Experimental Animals ◽  
Low Intensity ◽  
New Treatments ◽  
The Relationship

In recent decades, there has been a very rapid increase in the prevalence of diabetes globally, with serious health and economic implications. Although today there are several therapeutic treatments for this disease, these do not address the causes of the disease and have serious side effects, so it is necessary to seek new treatments to replace or complement the existing ones. Among these complementary treatments, a strong link between the intestinal microbiota and diabetes has been demonstrated, which has focused attention on the use of biotherapy to regulate the function of the intestinal microbiota and, thus, treat diabetes. In this way, the main objective of this work is to provide a review of the latest scientific evidence on diabetes, gathering information about new trends in its management, and especially, the influence of the intestinal microbiota and microbiome on this pathology. It is possible to conclude that the relationship between the intestinal microbiota and diabetes is carried out through alterations in energy metabolism, the immune system, changes in intestinal permeability, and a state of low-intensity systemic inflammation. Although, currently, most of the experimental work, using probiotics for diabetes management, has been done on experimental animals, the results obtained are promising. Thus, the modification of the microbiota through biotherapy has shown to improve the symptoms and severity of diabetes through various mechanisms related to these alterations.

scholarly journals Oral Candidiasis and COVID-19 in Users of Removable Dentures: Is Special Oral Care Needed?

Gerontology ◽  
2021 ◽  
pp. 1-6
Author(s):  
Laura Silva Jerônimo ◽  
Rafael Paschoal Esteves Lima ◽  
Thaís Yumi Umeda Suzuki ◽  
José Augusto César Discacciati ◽  
Cláudia Lopes Brilhante Bhering
Keyword(s):  
Mechanical Ventilation ◽  
Candida Albicans ◽  
Oral Health ◽  
Early Diagnosis ◽  
Elderly Patients ◽  
Oral Candidiasis ◽  
Oral Care ◽  
Antifungal Treatment ◽  
Immunocompromised Patients ◽  
Appropriate Care

Elderly patients with systemic disorders and immunocompromised patients seem to have a higher risk of developing morbidity from COVID-19. <i>Candida albicans</i> (<i>C. albicans</i>) is a potentially dangerous pathogen for these patients, especially for denture wearers with prosthetic stomatitis who require mechanical ventilation. <i>C. albicans</i> infection, the main candidiasis infection associated with denture wear, can complicate COVID-19 and increase the associated morbidity and mortality. Therefore, early diagnosis of <i>C. albicans</i> infection in COVID-19 patients is important to establish more effective antifungal treatment methods and prophylaxis strategies. Hospitalized COVID-19 patients should undergo an oral examination to assess their oral health, and those with poor oral health should receive the appropriate care and monitoring.

scholarly journals Prioritising recommendations following analyses of adverse events in healthcare: a systematic review

2020 ◽  
Vol 9 (4) ◽  
pp. e000843
Author(s):  
Kelly Bos ◽  
Maarten J van der Laan ◽  
Dave A Dongelmans
Keyword(s):  
Systematic Review ◽  
Adverse Events ◽  
Data Extraction ◽  
Data Sources ◽  
Cochrane Library ◽  
High Quality ◽  
Data Synthesis ◽  
Study Selection ◽  
Personal Opinion ◽  
User Friendly

PurposeThe purpose of this systematic review was to identify an appropriate method—a user-friendly and validated method—that prioritises recommendations following analyses of adverse events (AEs) based on objective features.Data sourcesThe electronic databases PubMed/MEDLINE, Embase (Ovid), Cochrane Library, PsycINFO (Ovid) and ERIC (Ovid) were searched.Study selectionStudies were considered eligible when reporting on methods to prioritise recommendations.Data extractionTwo teams of reviewers performed the data extraction which was defined prior to this phase.Results of data synthesisEleven methods were identified that are designed to prioritise recommendations. After completing the data extraction, none of the methods met all the predefined criteria. Nine methods were considered user-friendly. One study validated the developed method. Five methods prioritised recommendations based on objective features, not affected by personal opinion or knowledge and expected to be reproducible by different users.ConclusionThere are several methods available to prioritise recommendations following analyses of AEs. All these methods can be used to discuss and select recommendations for implementation. None of the methods is a user-friendly and validated method that prioritises recommendations based on objective features. Although there are possibilities to further improve their features, the ‘Typology of safety functions’ by de Dianous and Fiévez, and the ‘Hierarchy of hazard controls’ by McCaughan have the most potential to select high-quality recommendations as they have only a few clearly defined categories in a well-arranged ordinal sequence.

Recovery and Return to Activity Following Exertional Heat Stroke: Considerations for the Sports Medicine Staff

2007 ◽  
Vol 16 (3) ◽  
pp. 163-181 ◽  
Author(s):  
Brendon P. McDermott ◽  
Douglas J. Casa ◽  
Susan W. Yeargin ◽  
Matthew S. Ganio ◽  
Lawrence E. Armstrong ◽  
...  
Keyword(s):  
Data Extraction ◽  
Heat Stroke ◽  
Data Sources ◽  
Exertional Heat Stroke ◽  
Data Synthesis ◽  
Residual Symptoms ◽  
Study Selection ◽  
Initial Care ◽  
Type Data ◽  
Return To Activity

Objective:To describe the current scientific evidence of recovery and return to activity following exertional heat stroke (EHS).Data Sources:Information was collected using MEDLINE and SPORTDiscus databases in English using combinations of key words, exertional heat stroke, recovery, rehabilitation, residual symptoms, heat tolerance, return to activity, and heat illness.Study Selection:Relevant peer-reviewed, military, and published text materials were reviewed.Data Extraction:Inclusion criteria were based on the article’s coverage of return to activity, residual symptoms, or testing for long-term treatment. Fifty-two out of the original 554 sources met these criteria and were included in data synthesis.Data Synthesis:The recovery time following EHS is dependent on numerous factors, and recovery length is individually based and largely dependent on the initial care provided.Conclusion:Future research should focus on developing a structured return-to-activity strategy following EHS.

Effectiveness of Physical Therapy Treatments on Lateral Epicondylitis

2008 ◽  
Vol 17 (2) ◽  
pp. 119-136 ◽  
Author(s):  
Mohamed Kohia ◽  
John Brackle ◽  
Kenny Byrd ◽  
Amanda Jennings ◽  
William Murray ◽  
...  
Keyword(s):  
Physical Therapy ◽  
Treatment Options ◽  
Lateral Epicondylitis ◽  
Data Sources ◽  
Cochrane Library ◽  
Future Research ◽  
Data Synthesis ◽  
Study Selection ◽  
Type Data ◽  
Therapy Interventions

Objective:To analyze research literature that has examined the effectiveness of various physical therapy interventions on lateral epicondylitis.Data Sources:Evidence was compiled with data located using the PubMed, EBSCO, The Cochrane Library, and the Hooked on Evidence databases from 1994 to 2006 using the key words lateral epicondylitis, tennis elbow, modalities, intervention, management of, treatment for, radiohumeral bursitis, and experiment.Study Selection:The literature used included peer-reviewed studies that evaluated the effectiveness of physical therapy treatments on lateral epicondylitis. Future research is needed to provide a better understanding of beneficial treatment options for people living with this condition.Data Synthesis:Shockwave therapy and Cyriax therapy protocol are effective physical therapy interventions.Conclusions:There are numerous treatments for lateral epicondylitis and no single intervention has been proven to be the most efficient. Therefore, future research is needed to provide a better understanding of beneficial treatment options for people living with this condition.

scholarly journals The Prevalence and Occurrence of Candida albicans Among the Students of MAHSA University

2020 ◽  
Vol 2 (1) ◽  
pp. 89
Keyword(s):  
Candida Albicans ◽  
Oral Health ◽  
Oral Cavity ◽  
Health Knowledge ◽  
Study Group ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Unstimulated Saliva ◽  
Oral Health Practices ◽  
Self Administered Questionnaire

The study is done to identify the prevalence and occurrence of Candida albicans among the students of MAHSA University. It is also done to perform a cross-sectional survey by means of a self-administered questionnaire to assess the oral health knowledge, attitude, and practice (KAP) among the study group. Furthermore, it is done to determine the association of knowledge with attitude, oral health practices, and the prevalence of Candida albicans with the study group. The spores of Candida are a commensal, harmless form of a fungus that becomes invasive and pathogenic pseudohyphae when there is a disruption in the balance of flora. The infection that is caused by the yeast Candida albicans or even other candida species is candidiasis. Questionnaire on oral health was handed out to the students at random in MAHSA University, and upon that, samples are collected by taking their unstimulated saliva and are then pipetted on Sabouraud’s dextrose agar. These agar plates are then kept in an incubator at 37 ℃ for 2 days. After 2 days, the agar plates are then checked for any growth, and if there is the growth seen, gram stain and germ tube tests are done. It was seen that out of 100 samples collected, 40% were positive for Candida albicans, and 60% were negative for Candida albicans. And out of the percentage of positive samples, 26% were males, and 14% were females Candida albicans is the species most frequently implicated in the oral cavity, and it is important to take care of the oral cavity.

scholarly journals Role of Immunity in Pathogenesis of Psychosis

2021 ◽  
Author(s):  
Wafa Abdelghaffar ◽  
Oussama Sidhom ◽  
Lilia Laadhar ◽  
Rym Rafrafi
Keyword(s):  
Mental Health ◽  
Immune System ◽  
Psychiatric Symptoms ◽  
Scientific Evidence ◽  
Health Conditions ◽  
Future Research ◽  
Antineuronal Antibodies ◽  
System Components ◽  
The Brain

The involvement of immunity in the pathogenesis of schizophrenia and related psychoses was suspected a century ago but was shadowed by the dopaminergic hypothesis after the discovery of antipsychotics. We currently know that this latter theory has many limits and cannot account for the wide variety of psychotic conditions. The immune-inflammatory theory is now one of the most promising axes of research in terms of pathogenesis of several mental health conditions. Immunity and inflammation play a role at least in a subgroup of patients with psychosis. The immune system is complex with a variety of components and mediators that can all have effects on the brain and thus mediate psychiatric symptoms. In this chapter we will explore the scientific evidence of the role of immune system in pathophysiology of psychosis. The sections of this chapter will discuss the role of innate system components (cytokines, microglia, inflammation.), the role of adaptive system (lymphocytes and antibodies) with a section focusing on auto-immunity and particularly antineuronal antibodies. Finally we will discuss how this research can impact patients management and elaborate recommendations for future research.

scholarly journals Virulence Factor and Pathogenicity of Candida albicans in Oral Candidiasis

2013 ◽  
Vol 4 (4) ◽  
pp. 267-271 ◽  
Author(s):  
Abdillah Imron Nasution
Keyword(s):  
Antibiotic Resistance ◽  
Candida Albicans ◽  
Immune System ◽  
Virulence Factors ◽  
Virulence Factor ◽  
Oral Candidiasis ◽  
Complex Process ◽  
Phenotype Switching

ABSTRACT Candida albicans is an opportunistic fungus causing various forms of candidiasis. However, under certain circumstances it is capable of becoming pathogenic. Pathogenicity of oral candidiasis is a complex process and there is no one factor that can be regarded as the direct cause. This review aims to explain the virulence factors of Candida albicans in oral candidiasis infection and its relation to homeostasis in the mouth. Virulence factors of Candida albicans which is closely related to the nature of pathogens include: adherence and coaggregation, interference of immune system, phenotype switching and several supporting factors such as antibiotic resistance and immunomodulating. How to cite this article Nasution AI. Virulence Factor and Pathogenicity of Candida albicans in Oral Candidiasis. World J Dent 2013;4(4):267-271.

Sign in / Sign up

Export Citation Format

Share Document