scholarly journals EFFECT OF VAMAN IN STHUL MADHUMEHA: A CASE STUDY

2020 ◽  
Vol 11 (10) ◽  
pp. 12-16
Author(s):  
Sushil V Chawre ◽  
Sneha S Kamre ◽  
Prakash R Kabra

The study was conducted to evaluate cost effective and convenient treatment for Sthul Madhumeha in Ayurved. Diabetes is a group of metabolic diseases in which there are high blood glucose levels over a prolonged period. This high blood sugar produces the symptoms of frequent urination, increased thirst and increased hunger. Long term effect of Diabetes includes damage, dysfunction and failure of various organs. The long-term effects include progressive development of vasculopathy that may lead to renal failure, neuropathy etc. Prevalence of diabetes increased with age and reached at peaked at 60 to 69 years of age followed by declined at 70 years of age in India subjects. Ayurveda describes Prameha as a disease having cardinal features of “Prabhuta Avilamutrata’ which means excessive quantity and increased frequency of urine having turbid appearance. Ancient texts like Charak Samhita, Sushruta Samhita etc accepted that there are twenty types of Prameha according to Dosha. Charak has explained two different lines of treatment for both Sthula-pramehi and Krisha-pramehi types. Brihan to the Krish Pramehi and Apatarpana in the form of Shodhan and Shamana. The study was carried out to see the effect of Vaman Karma in the management of Prameha. To Study the effect of Vaman Karma in Prameha. A case study of 45 years old male patient with Adhaman, Udar-daha, Amlodgar, Katishula since 4-5 years, was treated with Vaman Karma followed by Ayurvedic drugs. A case recorded and treated in our institute. Significant results were seen in patient. Encouraging results were obtained which are presented in full paper.

1991 ◽  
Vol 13 (2) ◽  
pp. 96 ◽  
Author(s):  
GJ Mutze

Warren ripping and poisoning were used to control rabbits on the flood-out plain of a major creek system on Manunda Station, a sheep-grazing property near Yunta in semi-arid South Australia. Rabbit numbers were initially reduced by >99 per cent, as indicated by the number of active entrances remaining in rabbit warrens. After nearly 10 years without follow-up control work, ripped warrens had only two per cent of the pre-control number of active entrances. Poisoning effectively reduced rabbit numbers in the short-term, but had no long-term effect on the number of active entrances, either in ripped or unripped warrens. Perennial shrubs regenerated on and around ripped warrens. Warren ripping on this part of Manunda is a cost-effective management option.


2013 ◽  
Vol 91 (6) ◽  
pp. 412-420 ◽  
Author(s):  
Ryan James Wood-Bradley ◽  
Sarah Louise Henry ◽  
Amanda Vrselja ◽  
Victoria Newman ◽  
James Andrew Armitage

Over the past 100 years, advances in pharmaceutical and medical technology have reduced the burden of communicable disease, and our appreciation of the mechanisms underlying the development of noncommunicable disease has broadened. During this time, a number of studies, both in humans and animal models, have highlighted the importance of maintaining an optimal diet during pregnancy. In particular, a number of studies support the hypothesis that suboptimal maternal protein and fat intake during pregnancy can have long-term effects on the growing fetus, and increase the likelihood of these offspring developing cardiovascular, renal, or metabolic diseases in adulthood. More recently, it has been shown that dietary intake of a number of micronutrients may offset or reverse the deleterious effects of macronutrient imbalance. Furthermore, maternal fat intake has also been identified as a major contributor to a healthy fetal environment, with a beneficial role for unsaturated fats during development as well as a beneficial impact on cell membrane physiology. Together these studies indicate that attempts to optimise maternal nutrition may prove to be an efficient and cost-effective strategy for preventing the development of cardiovascular, renal, or metabolic diseases.


2002 ◽  
Vol 76 (17) ◽  
pp. 8864-8874 ◽  
Author(s):  
Yijan E. Chang ◽  
Loren Pena ◽  
Ganes C. Sen ◽  
Jung K. Park ◽  
Laimonis A. Laimins

ABSTRACT The long-term effects of interferon treatment on cell lines that maintain human papillomavirus type 31 (HPV-31) episomes have been examined. High doses and prolonged interferon treatment resulted in growth arrest of HPV-positive cells, with a high percentage of cells undergoing apoptosis. These effects were not seen with interferon treatment of either normal human keratinocytes or cells derived from HPV-negative squamous carcinomas, which exhibited only slight decreases in their rates of growth. Within 2 weeks of the initiation of treatment, a population of HPV-31-positive cells that were resistant to interferon appeared consistently and reproducibly. The resistant cells had growth and morphological characteristics similar to those of untreated cells. Long-term interferon treatment of HPV-positive cells also resulted in a reduction in HPV episome levels but did not significantly decrease the number of integrated copies of HPV. Cells that maintained HPV genomes lacking E5 were sensitive to interferon, while cells expressing only the E6/E7 genes were resistant. In contrast, cells that expressed E2 from a tetracycline-inducible promoter were found to be significantly more sensitive to interferon treatment than parental cells. This suggests that at least a portion of the sensitivity to interferon could be mediated through the E2 protein. These studies indicate that cells maintaining HPV episomes are highly sensitive to interferon treatment but that resistant populations arise quickly.


Author(s):  
Andrés Mideros

The paper reports on an ex-ante evaluation of the long-term effect of the Ecuadorian social transfer programme called “Bono de Desarrollo Humano (BDH)” on human capital accumulation. A dynamic cohort microsimulation model is used to analyse for cost-effectiveness of different policy scenarios. Results show that cash transfers do promotehuman capital accumulation but with rather small effect. Transfers targeted at critical ages are the most cost-effective to promote human capital accumulation


Author(s):  
Hao Yang ◽  
Zhiqiang Ma

While current research on the flipped classroom generally focuses on test results and (or) student/teacher perceptions as a measurement of its pedagogical efficacy, students' adaptation to it and the essential conditions for its application are rarely explored. This exploratory case study aims to rectify this by examining how university students adapted to flipped classrooms implemented in a public university in East China. The findings suggest that while the flipped model is impeded by entrenched polarity between students in terms of their learning dispositions and academic competence, students do develop a prototype of theories of learning, a sense of better self through learning from their peers and an awareness of the importance of intrinsic motivation. A gradualist approach is thus proposed for implementing flipped classrooms, which requires longitudinal studies accordingly to understand its long-term effects on learning behavior hitherto left unexplored.


2021 ◽  
Vol 12 (10) ◽  
pp. 1-6
Author(s):  
Deeya Baboo ◽  
Prajwal Narayan ◽  
Ganesh Puttur

Ayurveda (Science of life) has explained about the pathogenesis and the treatment of various disorders, the incidence of some of which have increased in the present scenario due to altered diet habits and lifestyle. Janu Sandhigata Vata is one among the Vata Vyadhi which causes a lot of inconvenience and disability in day-to-day activities. It is compared to Osteoarthritis of knee in modern Science. In this case study, a female aged about 57 years presented in the OPD of SSCASRH, Bengaluru was diagnosed with Janu Sandhigata Vata of both the knee joints. Arohana Krama Matra Basti with Prasarini taila was planned as per Sharangadhara’s reference. There was significant improvement in the patient and was evaluated after treatment and also during follow up. There was marked relief with respect to her subjective complaints like pain, improved joint space, walking time, degree of flexion and extension & X ray. This type of Arohana Krama Matra Basti can be adopted in future for planning treatment in Janu Sandhigata Vata and also taken up in a larger group study to check for better relief, long term effect and reduced side effects. The case is further elaborated in the article


2000 ◽  
Vol 59 (1) ◽  
pp. 47-54 ◽  
Author(s):  
S. M. Grantham-McGregor ◽  
S. P. Walker ◽  
S. Chang

The literature on the long-term effects of nutritional deficiencies in early life is reviewed. The severity and duration of the deficiency, the stage of the children’s development, the biological condition of the children and the socio-cultural context may all modify the effect. There is substantial evidence that reduced breast-feeding, small-for-gestational-age birth weight, Fe and I deficiency, and protein-energy malnutrition (PEM) are associated with long-term deficits in cognition and school achievement. However, all these conditions are associated with poverty and poor health, which may account for the association. It is difficult to establish that the long-term relationship is causal, as it requires a randomized treatment trial with long-term follow-up. Such studies are only available for I deficiency in utero and early childhood PEM. Results from these studies indicate that I deficiency has a long-term effect and PEM probably has a long-term effect.


2020 ◽  
Vol 295 (46) ◽  
pp. 15712-15726
Author(s):  
Bjoern O. Schroeder ◽  
George M. H. Birchenough ◽  
Meenakshi Pradhan ◽  
Elisabeth E. L. Nyström ◽  
Marcus Henricsson ◽  
...  

The intestinal mucus layer is a physical barrier separating the tremendous number of gut bacteria from the host epithelium. Defects in the mucus layer have been linked to metabolic diseases, but previous studies predominantly investigated mucus function during high-caloric/low-fiber dietary interventions, thus making it difficult to separate effects mediated directly through diet quality from potential obesity-dependent effects. As such, we decided to examine mucus function in mouse models with metabolic disease to distinguish these factors. Here we show that, in contrast to their lean littermates, genetically obese (ob/ob) mice have a defective inner colonic mucus layer that is characterized by increased penetrability and a reduced mucus growth rate. Exploiting the coprophagic behavior of mice, we next co-housed ob/ob and lean mice to investigate if the gut microbiota contributed to these phenotypes. Co-housing rescued the defect of the mucus growth rate, whereas mucus penetrability displayed an intermediate phenotype in both mouse groups. Of note, non-obese diabetic mice with high blood glucose levels displayed a healthy colonic mucus barrier, indicating that the mucus defect is obesity- rather than glucose-mediated. Thus, our data suggest that the gut microbiota community of obesity-prone mice may regulate obesity-associated defects in the colonic mucosal barrier, even in the presence of dietary fiber.


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