scholarly journals Assessment of Methaemoglobin in Haemoglobin Variants in Selected Ethnic Groups in Bayelsa State

2021 ◽  
pp. 1-5
Author(s):  
Victor Tuanwii Ideede ◽  
Jeremiah Awotu Zaccheus ◽  
Everlyn Mercy Eze ◽  
Jonathan Nyebuchi ◽  
Friday Ogidigba ◽  
...  
Keyword(s):  
Blood Sample ◽  
Ethnic Group ◽  
Ethnic Groups ◽  
Spectrophotometric Method ◽  
Mean Difference ◽  
P Value ◽  
Heme Group ◽  
Significant Difference ◽  
Post Hoc

Methaemoglobin (Met-Hb) is a type of the oxygen-carrying metalloproteinhemoglobin. The heme group iron exists as ferric (Fe3+) iron, rather than the ferrous (Fe2+) iron of typical hemoglobin. Met-Hb is unable to perform the function of binding to oxygen like oxyhaemoglobin does. The aim of this study was to compare methaemoglobin levels between AA and AS haemoglobin variants among the Ijaw, Igbo and Yoruba ethnic groups residing in Bayelsa State, Nigeria. A total of 150 subjects were enrolled for the study. One hundred and sixteen subjects constituted the Ijaws; 21 Igbos and 13 Yorubas. For each subject, 4mls of blood sample collected in EDTA bottle was assayed for methaemoglobin using a spectrophotometric method. Results revealed there was no significant difference in the methaemoglobin mean levels between the AA and AS haemoglobin variants (P-value>0.05) of the ethnic groups except the Igbo ethnic group (P-value <0.05). However, comparing the methaemoglobin mean levels among the ethnic groups showed a significant mean difference of methaemoglobin (P-value <0.05). All Post-hoc groups showed significant difference except the Igbo and Yorubo ethnic groups (P-value >0.05). In conclusion, this study has revealed that methaemoglobin levels changes significantly based on studied tribes but does not change based on studied haemoglobin variants.

scholarly journals Lower Jaw and Orolabial Analysis in Adult Bangladeshi Buddhist Chakma Females

2013 ◽  
Vol 12 (3) ◽  
pp. 5-8 ◽  
Author(s):  
Asma Mostafa ◽  
Laila Anjuman Banu ◽  
Azmeri Sultana
Keyword(s):  
Ethnic Group ◽  
Ethnic Groups ◽  
Age Groups ◽  
P Value ◽  
Cross Sectional ◽  
Morphological Variations ◽  
Lower Jaw ◽  
Age Related ◽  
Significant Difference ◽  
Two Age Groups

Background: It is well accepted that a single standard of craniofacial norms is not appropriate for application to diverse racial and ethnic groups, even for different sex and ages in same ethnic group. So it is necessary to develop craniofacial norms for different groups based on above factors. The present study was designed to establish the baseline measurements of the lower jaw and orolabial anthropometrical parameters and indices, and also to evaluate the differences (if any) on age related morphological variations of adult Bangladeshi Buddhist Chakma females. Methods: The study was descriptive, observational and cross-sectional in nature with some analytical components. The study group consisted of a convenient sample of 100 adult Bangladeshi Buddhist Chakma females; categorized into two groups – 25 to 35 years (n = 70) and 35 to 45 years (n = 30). Variables were measured using physical and photographic procedures. Indices were calculated from those variables. An independent “t” test was performed to evaluate if there was any significant difference in measurements between the two age groups setting a p value of <0.05 as statistically significant. Results: All measurements show statistically non significant difference between two age groups except philtrum length (p = 0.02) and upper vermilion height to philtrum length index (p = 0.03). Conclusions: The result of this study can be useful for anatomists and anthropologists to serve as a basic framework for estimating the standard of lower jaw and orolabial dimensions of this population and also to compare the craniofacial dimensions of other ethnic groups of Bangladesh with this ethnic group. Chattagram Maa-O-Shishu Hospital Medical College Journal Volume 12, Issue 3, September 2013: 5-8

Variations in Facial Anthropometric Measurements among Major Ethnic Groups in Nigeria: A 3-Dimentional Stereophotogrammetry Analysis

FACE ◽  
2021 ◽  
pp. 273250162110290
Author(s):  
Adegbayi Adeola Adekunle ◽  
Abiodun Yusuff Olowo ◽  
Moses Adetona ◽  
Olutayo James ◽  
Olawale Olatubosun Adamson ◽  
...  
Keyword(s):  
Ethnic Group ◽  
Ethnic Groups ◽  
Imaging System ◽  
Descriptive Analysis ◽  
Multivariate Regression Analysis ◽  
Mean Difference ◽  
Anthropometric Measurements ◽  
Lower Lip ◽  
Facial Height ◽  
3D Photogrammetry

Objectives: The aim of the study is to highlight variations in facial anthropometric measurements among the major ethnic groups in Nigeria using 3D photogrammetry. Materials and Methods: This study was conducted in Lagos, Nigeria. Acquisition of 3D facial photographs was done using a Vectra H1 portable 3D photogrammetry imaging system. Descriptive analysis of collected data was done and a test of associations performed using independent samples t-test. The level of significance was set at <.05. Results: The total number of participants in this study was 503. The study population was made up of 302 (60%) males and 201 (40%) females. Mean upper facial height among Yoruba, Igbo, Hausa, and other ethnic groups were 68.93 ± 5.85, 70.18 ± 5.99, 63.79 ± 4.80, and 69.29 ± 5.95 mm respectively, while mean interpupillary distances were 66.99 ± 3.70, 67.34 ± 3.56, 66.73 ± 3.80, and 67.09 ± 3.72 mm respectively. A Tukey posthoc test revealed significant pairwise differences for upper facial height between the Yoruba and Hausa population with a mean difference of 5.15 mm ( P < .001, 95% CI 2.94-7.35) ( P < .001, 95% CI 2.94-7.35), and Hausa and Igbo population with a mean difference of 6.39 mm ( P < .001, 95% CI 3.75-9.03). Multivariate regression analysis confirmed the presence of significant inter-ethnic differences between Hausa ethnic group and the Yoruba ethnic group for midfacial height ( P < .001), upper lip height ( P = .004), lower lip height ( P = .003), total face height ( P = .010), and orbital fissure width ( P < .001). Conclusion: The result of this study shows that distinct difference does exist in the facial anthropological measurements between the ethnicities included in this study especially in vertical facial measurements.

TO COMPARE THE EFFECTIVENESS OF NEBULISATION WITH ADRENALINE, 3% HYPERTONIC SALINE AND NORMAL SALINE IN BRONCHIOLITIS IN CHILDREN OF 2 TO 24 MONTHS OF AGE BASED ON CLINICAL SEVERITY SCORE AND NEBULISATION FREQUENCY.

2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Priyanka Jain ◽  
Rakesh Jain
Keyword(s):  
Hypertonic Saline ◽  
Normal Saline ◽  
Mean Difference ◽  
Clinical Severity ◽  
Research Centre ◽  
P Value ◽  
College Hospital ◽  
Mean Values ◽  
Significant Difference ◽  
The Mean

Background & Method: We conducted a double blinded study at Index Medical College Hospital & Research Centre, Indore. The sample size was determined to be minimum of 120 cases as based upon previous years admission due to acute bronchiolitis. Initially, 146 cases were included in the study out of which 23 cases dropped out of the study after giving consent by guardian for participation in the study as they left against medical advice from the hospital. Result: The mean difference of CSS between 0 minutes to 60 minutes of nebulisation between groups in all cases was 0.4 ± 0.6, between 60 minutes and 4 hours was 0.8 ± 0.6, between 4 to 8 hours was 0.7 ± 0.6, between 8-12 hours was 0.6 ± 0.4, between 12-24 hours was 1.6 ± 0.9 and between 24-48 hours was 1.9 ± 0.9.The mean values and resultant p-value of ANOVA of various nebulising agents used for improvement in CSS shows significant association between various nebulising agents used along with improvement in CSS at the end of assessment at 48 hours of treatment. Conclusion: This study was conducted to establish the efficacy of each nebulisation agent (i.e.  adrenaline, 3% hypertonic saline and normal saline) currently used and compare the outcomes as there is not enough evidence amongst Indian population on level of efficacy of each drug in causing improvement in symptoms and signs in various severities of bronchiolitis in early childhood. Comparison of significant improvement in mean difference in CSS at various intervals in all cases compared between groups by post hoc test revealed non-significant difference (p-value 0.700) between 3% hypertonic saline and normal saline. Keywords: nebulisation, adrenaline, bronchiolitis & clinical.

scholarly journals Variation in lip print pattern between two ethnic groups, Oraon tribals and Bengalee Hindus, residing in West Bengal, India

2019 ◽  
Vol 82 (4) ◽  
pp. 405-415
Author(s):  
Archita Dey ◽  
Mahua Chanak ◽  
Kaustav Das ◽  
Koel Mukherjee ◽  
Kaushik Bose
Keyword(s):  
Ethnic Groups ◽  
West Bengal ◽  
Personal Identification ◽  
P Value ◽  
Type Ii ◽  
Ethnic Variation ◽  
Criminal Cases ◽  
Chi Square ◽  
Significant Difference ◽  
Chi Square Test

Abstract Lip print pattern (LPP) is unique to each individual. For decades, forensic experts have used LPP for personal identification to solve criminal cases. However, studies investigating ethnic variation in LPP are scanty. Our study wanted to investigate variation in LPP between two ethnic groups, Oraon tribals and Bengalee Hindus, residing in West Bengal, India. A total of 280 participants included 112 Oraons and168 Bengalee Hindus of both. Prints were taken using dark shaded lipstick and transparent cellophane tape and recorded into white A4 sheet. Prints were divided into four quadrants and examined by magnifying glass. For analysis of results, classification of Suzuki and Tsuchihashi was followed. A p value of 0.05 was considered to be statistically significant. It was observed that Type II pattern was dominant in first and second quadrants in both ethnic groups, irrespective of sex. Combination of Type II+III was found to be the most common pattern in males among both Oraons (16.2%) and Bengalee Hindus (12.2%) whereas in females Type II pattern (25.0%) among Oraons and Type III pattern among Bengalee Hindus (11.4%) was the most common. Chi square test showed statistically significant difference among females (p<0.05) and in third and fourth quadrants among males (p<0.01) of both ethnic groups. Our investigation clearly demonstrated sex and ethnic variations in LPP. Further studies are required to investigate ethnic variation in LPP among the various populations groups, both tribal as well as non-tribal, from different regions of India.

scholarly journals Difference of Procalcitonin Levels in Gram-Positive and Gram-Negative Bacterial Sepsis Patients of Indonesia Army Central Hospital Gatot Soebroto in 2016

2022 ◽  
Vol 13 (1) ◽  
pp. 38
Author(s):  
Nindy Handayani ◽  
Soroy Lardo ◽  
Nunuk Nugrohowati
Keyword(s):  
Mean Difference ◽  
P Value ◽  
Central Hospital ◽  
Bacterial Sepsis ◽  
Gram Positive ◽  
Cross Sectional ◽  
Gram Negative ◽  
Gram Positive Bacteria ◽  
Significant Difference ◽  
The Mean

Introduction: Procalcitonin is known as a marker of infection and indicator for severity of infections. In sepsis, elevated procalcitonin levels in blood have a significant value that can be used as a sepsis biomarker. The aim of this study was to determine the mean difference of procalcitonin levels in Gram-positive and Gram-negative bacterial sepsis patients.Methods: This study used quantitative method with cross sectional approach. The sample of this study were bacterial sepsis patients of Indonesia Army Central Hospital Gatot Soebroto in 2016 which were divided into two groups: Gram-positive and Gram-negative bacterial sepsis patients with the number of each group was 30 samples. The data were analyzed by using independent t test.Results: This study showed that mean levels of procalcitonin in Gram-positive bacterial sepsis patients was 6.47 ng/ml and Gram-negative was 66.04 ng/ml. There was a significant difference between mean levels of procalcitonin in Gram-positive and Gram-negative bacterial sepsis patients of Indonesia Army Central Hospital Gatot Soebroto in 2016 with p value = 0.000 (p < 0.05).Conclusion: The mean difference of procalcitonin levels in Gram-negative bacterial sepsis patients were higher than Gram-positive bacterial sepsis patients, because Gram-negative bacteria have lipopolysaccharide which is a strong immunostimulator and increases TNF-α production higher than Gram-positive bacteria. 

scholarly journals Perceived Discrimination Difference between the Manjo Minority and Non-Manjo Ethnic Group in Kaffa Zone, Ethiopia

2020 ◽  
Vol 9 (9) ◽  
pp. e626997386
Author(s):  
Bizuayehu Dengechi Dachachi ◽  
Nigatuwa Worku Woyessa ◽  
Fisseha Mikre Weldmeskel
Keyword(s):  
Social Work ◽  
Ethnic Group ◽  
Ethnic Groups ◽  
Perceived Discrimination ◽  
T Test ◽  
Mean Difference ◽  
The South ◽  
Psychosocial Wellbeing ◽  
South West ◽  
Work Intervention

This study has attempted to examine perceived discrimination difference between the Manjo clan and non-manjos in Kaffa zone that is located in the south west of Ethiopia. A total of 298 individuals who belong to the manjo and non-manjo groups were randomly selected and involved in the study. The researchers utilized an independent sample t-test to compare the level of perceived discrimination between the Manjo and the non-Manjos ethnic groups. Seen segregation is the changeability of thought coming because of behavior of isolating group of people that radiates from predisposition and partiality. As revealed in the study, there is a significant mean variation among manjos and non-manjos with respect to perceiving discrimination. The thought of being discriminated showed significant mean difference between the group of manjos and non-manjos. The finding implies the need for further research and social work intervention to minimize the action and sense of being discriminated as this relates to the overall psychosocial wellbeing of persons in a given community.

Abstract 17062: Can Automated Rate-only CPR Feedback be Detrimental to Chest Compression Depth? A CPR Simulation Study of 141 Untrained Operators

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Hannah Torney ◽  
Peter O'Hare ◽  
Laura Davis ◽  
Bruno Delafont ◽  
Ben McCartney ◽  
...  
Keyword(s):  
Chest Compression ◽  
Mean Difference ◽  
Public Access ◽  
Shopping Mall ◽  
P Value ◽  
Compression Rate ◽  
Compression Depth ◽  
Rate Feedback ◽  
Significant Difference ◽  
Machine Interface

Introduction: A number of public access defibrillators incorporate computerised audio-visual feedback mechanisms to help responders deliver cardiopulmonary resuscitation (CPR) according to current guidelines. A 2013 American Heart Association statement suggested that chest compression fraction (CCF) and compression rate should be prioritised over compression depth, chest recoil and ventilations. This usability study assessed the effect of real-time rate-only feedback on chest compression depth. Methods: Randomly selected users were recruited in a shopping mall (n=141; 15-65+ years) to deliver CPR using a public access defibrillator in a simulated scenario. Participants were randomly assigned one of two devices - (1) with CPR rate feedback in the form of a machine-interface comprising of audio-voice prompts and light emitting diodes; (2) without CPR feedback. Participants were instructed to turn on the device and follow the prompts, with no information on how to perform CPR provided. CPR rate and depth were captured by measuring displacement of a potentiometer contained in a specially designed manikin. The device was connected to the manikin via the electrode leads. The effect of rate-only feedback on compression depth and CPR fraction were assessed. Results: ANCOVA analysis between the two devices provided a mean difference (Standard Error; SE) of 4.52mm (1.38mm) indicating a statistically significant difference (p-value=0.001) between measured CPR depth favouring the device with CPR rate feedback. There was no significant difference in CCF between the devices. ANCOVA analysis provided a mean difference (SE) of 2.9% (1.9%) for the device with CPR rate feedback compared to the device without CPR rate feedback. Conclusion: The incorporation of clear, intuitive, audio-visual machine-interface that delivers CPR feedback can assist trained and untrained users in the optimisation of chest compression rate and maintain a high CCF. In conclusion, CPR rate-only feedback was not detrimental to chest compression depth and suggests rate-only feedback may improve compression depth.

Seroepidemiology ofToxoplasma gondiiinfection in Bai and Han ethnic groups in southwestern China

2014 ◽  
Vol 143 (4) ◽  
pp. 881-886 ◽  
Author(s):  
H.-L. LI ◽  
L. DONG ◽  
Q. LI ◽  
L. ZHANG ◽  
J. CHEN ◽  
...  
Keyword(s):  
Ethnic Group ◽  
Ethnic Groups ◽  
Rural Areas ◽  
Southwestern China ◽  
Enzyme Linked Immunosorbent Assay ◽  
Unique Region ◽  
Significant Difference ◽  
Positive Rate ◽  
Urban And Rural Areas ◽  
And Control

SUMMARYEating raw pork and/or liver is a custom of the Bai ethnic group in China. Most people living in Dali Bai Autonomous Prefecture, Yunnan Province, southwestern China are of Bai ethnicity. Little is known of the seroprevalence ofToxoplasma gondiiin Bai and Han ethnic populations in this region. In the present survey, a total of 555 and 595 blood samples were obtained from Bai and Han ethnic groups in Dali urban and rural areas, respectively. Enzyme-linked immunosorbent assay was performed to examineT. gondiiIgG antibodies. Total positive rate of anti-T. gondiiIgG in Bai and Han groups in this region was 21·6% (248/1150). The total seroprevalence ofT. gondiiwas significantly higher in the Bai ethnic group (32·3%, 179/555) than in the Han ethnic group (11·6%, 69/595) (P < 0·01). The results of statistical analysis indicated that there was no significant difference between cat feeding/non-cat feeding groups in the Bai ethnic group, the most important risk factor was consumption of raw pork and/or liver for the Bai group, but feeding a cat may be the main route ofT. gondiiinfection for the Han group. Therefore, it is essential to implement integrated strategies to prevent and controlT. gondiiinfection in this unique region of the world.

scholarly journals Efektifitas Variasi Umpan Pada Fly Trap Dalam Pengendalian Kepadatan Lalat Di Tempat Pembuangan Sementara (TPS) Jalan Andong Yogyakarta

2020 ◽  
Vol 20 (1) ◽  
pp. 59-64
Author(s):  
Eva Fitriana ◽  
Surahma Asti Mulasari
Keyword(s):  
Experimental Study ◽  
High Population ◽  
Disposal Site ◽  
P Value ◽  
Significant Difference ◽  
The One ◽  
Post Hoc ◽  
One Way Anova

Latar Belakang: Lalat merupakan salah satu serangga yang memiliki populasi tinggi di lingkungan masyarakat. Lalat berperan dalam penularan penyakit pada manusia seperti disentri, tifoid, kolera infeksi cacing, conjungtivitis, trachoma kusta, mikosis, dan difteri kutaneus. Fly trap digunakan untuk pengendalian lalat dewasa dalam jumlah besar dan padat. Penerapan Fly trap dilakukan diluar rumah pada udara terbuka dan tidak terhindar dari pepohonan. Penggunaan alat ini berpasangan dengan umpan yang digunakan untuk menarik lalat dengan bau dan kandungan pada umpan. Penelitian ini dilakukan untuk mengetahui efektifitas variasi umpan pada Fly trap dalam pengendalian lalat di tempat pembuangan sementara (TPS) Jalan Andong Yogyakarta.Metode: Penelitian ini merupakan penelitian eksperimen dengan variasi umpan ikan, udang, buah nangka, terasi, dan buah mangga. Pengukuran dilakukan pada radius ± 1 Meter dari tumpukan sampah dan dibiarkan selama 2 jam selanjutnya lalat yang terperangkap dihitung menggunakan handcounter. Data yang diperoleh dianalisis menggunakan uji One Way Anova dengan derajat kesalahan α 0.05 dan dilanjutkan uji Post hoc Tamhanne.Hasil: Hasil penelitian menunjukan terdapat hasil yang signifikan rata-rata lalat yang terperangkap pada Fly trap dengan umpan terasi dan umpan udang diperoleh nilai p=0,042 (p<α). Terdapat perbedaan bermakna antara umpan terasi dan umpan udang. Lalat yang terperangkap pada Fly trap umpan terasi sebanyak 69 ekor lalat, dan lalat yang terperanfkap pada Fly trap umpan udang sebanyak 1123 ekor lalat.Simpulan: Ada perbedaan rata-rata lalat yang terperangkap pada Fly trap umpan ikan, udang, buah nangka, terasi dan buah mangga. Terdapat perbedaan bermakna rata-rata lalat yang terperangkap antara Fly trap umpan terasi dan umpan udang. ABSTRACT Title: The Effectivennes of various feed variations in the fly trap as a control of fly density at the Andong street Yogyakarta.Background: Flies are one of the insects that have a high population in the community. Flies play a role in transmitting disease to humans such a dysentery, typoid, cholera, worm infection, conjungtivitis, leprosy trachoma, mycosis and cutaneus diphteria. Fly traps are used fpr the control of large and dense adult flies. The application on fly traps is carried out outside the house in the open air and is not spared from trees. The use of this tool is paired with the bait used the attract flies to get closer to the smell and content of the bait, this research was conducted to determine the effectiveness of bait varians in the fly trap in controlling flies at the temporary disposal site (TPS) at the Andong street Yogyakarta.Method: This research was a experimental study with a variety of bait fish, shrimp, jackfruit, shrimp paste, and mango. Measurements were made at radius of ± 1 meter from the garbage pile. The data obtained were analyzed using the One Way Anova tesy with an error degree of α=0,05 and continued with the Post hoc Tamhanne test.Result: The result showed that there were significant result on the average of flies trapped in the fly trap with the shrimp paste bait and shrimp bait obtained p value = 0.042 (p<α). That there was a significant difference between shrimp paste bait and shrimp bait.Conclusions: There was a difference in the average number of flies trapped in fly traps for fish, shrimp, jackfruit, shrimp paste, mango. There was a significant difference of flies trapped between shrimp paste bait and shrimp bait. Fly trap shrimp bait is the most preferred bait by flies shrimp paste bait is the least preferred bait by flies.  

scholarly journals The effect of combination probiotic lactobacillus brevis and leuconostoc mesenteroides on tgf-β and il-12 expression in ileum

2022 ◽  
Vol 21 (1) ◽  
pp. 175-183
Author(s):  
- Pujiati ◽  
Dono Indarto ◽  
- Susilorini ◽  
Diani Retno Widyatuti ◽  
Haneda Ilzafira Damayanti ◽  
...  
Keyword(s):  
Leuconostoc Mesenteroides ◽  
Lactobacillus Brevis ◽  
Combination Group ◽  
Control Group ◽  
P Value ◽  
Anova Test ◽  
Significant Difference ◽  
Post Hoc ◽  
One Way Anova ◽  
Asthma Group

Background: Asthma is a disease of the respiratory tract in the form of chronic inflammation. Chronic inflammation is one of them characterized by the remodeling of the airways mediated by the anti-inflammatory cytokine TGF-β. In addition there are also several immune cells that play a role such as macrophages, dendritic, neutrophils as producers of IL-12. The presence of the gut-lung axis allows the spread of inflammatory cytokines from the lungs to the intestines and vice versa. Lactobacillus brevis and Leuconostoc mesenteroides have the potential to modulate the immune system through its colonization of the gut. The study aimed to look at the effect of probiotics combined Lactobacillus brevis and Leuconostoc mesenteroides on the expression of TGF-β and IL-12 in the asthma model mouse ileum. Method: This experimental post-test only control group design study used 18 Sprague-Dawley mice. The mice were divided into 3 groups at random: control group (KI), asthma treatment (KII), asthma treatment with a combination of Lactobacillus brevis and Leuconostoc mesenteroides (KIII). Sensitization of asthma with OVA through intraperitoneal injection on days 0 and 14 and through inhalation on days 21 -63. Administration of combination probiotics per oral per day on days 21-63 after inhalation of OVA. The ileum network was taken on the 64th day and measured the expression of TGF-βand IL-12 with immunohistochemical methods and analyzed the percentage proportion of TGF-βand IL-12. Data analysis were conducted by One way ANOVA test and continued post hoc tests. Results: The percentage calculation of the proportion of TGF-βin thecontrol group (KI), asthma group (KII), and the combination group of L.brevis and L.mesenteroides (KIII) is 22.4 ± 15.27; 1.6 ± 2.12; 19.4 ± 6.65. While the percentage calculation of il-12 proportion in each group consecutively were 24.3 ± 19.67; 64.63 ± 9.90; 51 ± 16.62. One way ANOVA Test results on the percentage proportion of TGF-βhave a p value of 0.013 (p<0.05) which means there is a significant difference in the entire group. Furthermore, the Post Hoc Games-Howell test was conducted and obtained a p value of 0.003 (p<0.05) between the asthma group (KII) and the combination group of L.brevis and L.mesenteroides (KIII) which means there are significant differences between the two groups. One way ANOVA Test results on the percentage proportion of IL-12 have a p value of 0.011 (p<0.05) which means there is a significant difference in the entire group. Furthermore, the Post Hoc LSD test was conducted and obtained a p value of 0.001 (p<0.05) between the control group Post Hoc analyses was conducted and obtained a p value of 0.002 (p<0.05) with number of errors was 11.353 between the control group (KI) and asthma group (KII) which means there are significant differences between the two groups. Conclusion: The probiotic administration of lactobacillus brevis and Leuconostoc mesenteroides had no effect on the expression of TGF-β and had no effect on il-12 expression in the asthma model mouse ileum. It is necessary to do research on mice with asthma using combinations with other bacteria in order to get maximum effect. Bangladesh Journal of Medical Science Vol. 21(1) 2022 Page : 175-183

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