scholarly journals Seasonal Depiction of Malariometric Indices in Children under Five Years in a Sudanese Semi-urban Area of Burkina Faso

Author(s):  
San M. Ouattara ◽  
Alphonse Ouédraogo ◽  
Alfred B. Tiono ◽  
Benjamin Sombié ◽  
Amidou Diarra ◽  
...  

Aims: Malariometric indices are essential for the assessment of both new therapies and control strategies. As part of the characterization of a new malaria clinical trial site, this study was carried out to assess malariometric indices during the two seasons of a Sudanese area of Burkina Faso, in children aged under five years. Study Design: Two community-based cross-sectional surveys were conducted as follow: the first during the rainy season of 2009 and the second during the following dry season. Socio-demographic and clinical data were recorded. A finger prick blood sample was collected to perform malaria blood films and to measure the hemoglobin level. Results: Malaria parasitemia prevalence was 55.2% (N = 677) in the rainy season with a geometric mean of parasite density (GMPD) of 3439 trophozoites/µl against 23.3% (N = 720) in the dry season with a GMPD of 1368 trophozoites/µl. Gametocytemia prevalence was 21.7% and 6.5% respectively in rainy and dry season while splenomegaly prevalence was 11.2% (N = 689) in rainy season against 4.2% (N = 752) in dry season. The prevalence of anemia (hemoglobin < 11.0 g/dl) was 90.0% in rainy season and 70.6% in dry season. All indices in rainy season were statistically higher than those in dry season (p-value < 0.0001). The odds of parasite carriage were 3 to 5 times higher in rainy season compared to dry season (95% CI for OR = [3.1, 5.0]). Conclusion: The site is located in a seasonal hyper-endemic malaria area and seems appropriate for the conduct of malaria drugs or vaccines studies. Though the gap between seasons is considerable, the residual level of parasite carriage during low transmission period is not negligible and may command the development of strategies targeting this specific period, to break the chain of transmission of the disease.

2011 ◽  
Vol 86 (4) ◽  
pp. 418-425 ◽  
Author(s):  
K.S. Nalubamba ◽  
N.B. Mudenda ◽  
M.R. Malamo

AbstractFaecal samples (n = 1947) from captive wild impala (Aepyceros melampus melampus) were examined over a period of 14 months to determine quantitative seasonal helminth egg excretion patterns and qualitative protozoan oocyst excretion patterns. Geometric mean monthly faecal egg counts (FECs) ranged from 20 to 575 and coprocultures revealed three parasite genera, namely Trichostrongylus, Haemonchus and Strongyloides. Larvae of the Trichostrongylus spp. were most predominant from faecal cultures. No trematode eggs or lungworms were detected and eggs of the cestode Monezia were only seen in two samples during the entire study period. The nematode FECs showed a marked seasonal variation, being higher during the rainy season, moderate during the cool dry season and low during the hot dry season. The rainy season had significantly higher FECs than the dry season (P < 0.01). The percentage of helminth-egg positive faecal samples ranged from 90.6 to 100% in the rainy season and 72.4 to 85.6% in the dry season. Overall mean FECs in unpelleted faeces were significantly higher than in pelleted faeces (P < 0.01). However, the FECs were not significantly different among seasons in unpelleted faeces (P>0.05), but were significantly higher in pelleted faeces in the rainy season than the dry season (P < 0.05). Pellet size had a significant effect on FEC, with smaller pellets having higher FEC (P < 0.05). Strongyloides eggs and coccidia oocysts were only seen during the rainy season. This represents the first documentation of seasonal parasitic infestation in captive wild antelopes in Zambia. Treatment and control strategies for helminths in these captive wild impala are also suggested based on the findings from this study.


2021 ◽  
Author(s):  
Mamoudou Cisse ◽  
Ibrahim Sangare ◽  
Arthur D. Djibougou ◽  
Marc C. Tahita ◽  
Souleymane Gnissi ◽  
...  

Abstract BackgroundSchistosomiasis remains a major public health concern in sub-Saharan Africa. Although schistosomiasis is well documented in school-aged children in Burkina Faso, prevalence data among preschool-aged children (PSAC) are limited and outdated, and its risk factors in this group remain poorly documented. The main objective of this study was to assess the prevalence and risk factors associated with Schistosoma (S.) mansoni infection among PSAC from Panamasso village, western Burkina Faso.MethodologyA cross-sectional study was carried out among 228 children under 6 years old from Panamasso village. Sociodemographic and water contact data were collected using a structured questionnaire. Kato-Katz and formol-ether concentration techniques were used to detect S. mansoni eggs in stool samples. Urine samples were subjected to a point-of-care circulating cathodic antigen (POC-CCA) cassette test and a centrifugation method to check for both S. mansoni and S. haematobium infection, respectively. Potential risk factors for S. mansoni infection were explored using multivariable logistic regression.ResultsThe mean age of children was 40.2 ± 15.0 months. The prevalence of S. mansoni infection as determined by Kato-Katz, formol-ether concentration, and POC-CCA was 42.1%, 39.5% and 80.7%, respectively. Based on the combined results of the three methods, the overall prevalence of S. mansoni infection was 81.1%. No case of S. haematobium infection was found. The geometric mean intensity of S. mansoni infection was 107.2 eggs per gram of faeces with 54.2%, 33.3%, and 12.5% of the children having light, moderate, and heavy infections, respectively. Girls (AOR = 2.9, 95% CI: 1.3-6.1), a household located within 500 m from the pond (AOR = 3.0, 95% CI: 1.0-8.6), or between 500 and 1000 m from the pond (AOR = 3.0, 95% CI: 1.2-7.2), and child’s history of going to the pond (AOR = 5.0, 95% CI: 1.7-14.3) were the variables significantly associated with S. mansoni infection. ConclusionS. mansoni was the sole species infecting a high proportion of PSAC in the study area. A mass drug administration program with praziquantel is therefore urgently required for those below 6 year-old. Other control strategies should include increased community-awareness and provision of safe water.


2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Mamoudou Cisse ◽  
Ibrahim Sangare ◽  
Arthur D. Djibougou ◽  
Marc C. Tahita ◽  
Souleymane Gnissi ◽  
...  

Abstract Background Schistosomiasis remains a major public health concern in sub-Saharan Africa. Although schistosomiasis is well documented in school-aged children in Burkina Faso, prevalence data among preschool-aged children (PSAC) are limited and outdated, and its risk factors in this group remain poorly documented. The main objective of this study was to assess the prevalence and risk factors associated with Schistosoma (S.) mansoni infection among PSAC from Panamasso village, western Burkina Faso. Methodology A cross-sectional study was carried out among 228 children under 6 years old from Panamasso village. Sociodemographic and water contact data were collected using a structured questionnaire. Kato-Katz and formol-ether concentration techniques were used to detect S. mansoni eggs in stool samples. Urine samples were subjected to a point-of-care circulating cathodic antigen (POC-CCA) cassette test and a centrifugation method to check for both S. mansoni and S. haematobium infection, respectively. Potential risk factors for S. mansoni infection were explored using multivariable logistic regression. Results The mean age of children was 40.2 ± 15.0 months. The prevalence of S. mansoni infection as determined by Kato-Katz, formol-ether concentration and POC-CCA was 42.1%, 39.5% and 80.7%, respectively. Based on the combined results of the three methods, the overall prevalence of S. mansoni infection was 81.1%. No case of S. haematobium infection was found. The geometric mean intensity of S. mansoni infection was 107.2 eggs per gram of feces with 54.2%, 33.3% and 12.5% of the children having light, moderate and heavy infections, respectively. Girls (AOR = 2.9, 95% CI 1.3–6.1), a household located within 500 m from the pond (AOR = 3.0, 95% CI 1.0–8.6) or between 500 and 1000 m from the pond (AOR = 3.0, 95% CI 1.2–7.2), and the child’s history of going to the pond (AOR = 5.0, 95% CI 1.7–14.3) were the variables significantly associated with S. mansoni infection. Conclusion S. mansoni was the sole species infecting a high proportion of PSAC in the study area. A mass drug administration program with praziquantel is therefore urgently required for those below 6 years old. Other control strategies should include increased community-awareness and provision of safe water.


2020 ◽  
Author(s):  
Anthony Somé ◽  
Issaka Zongo ◽  
Bertin N’cho Tchiekoi ◽  
Dieudonné D. Soma ◽  
Barnabas Zogo ◽  
...  

AbstractBackgroundThe objective of this study was to update malaria epidemiological profile prior to the implementation of a randomized controlled trial aiming to evaluate the efficacy of new vector control tools in complementary to the use of long-lasting insecticidal nets in Burkina Faso.MethodsWe carried out active and passive cross-sectional surveys to estimate the prevalence and incidence of malaria infection from August 2016 to July 2017 in 27 villages of the Diebougou health district.ResultsWith the passive survey, we extracted data from 4814 patients included in the study from August 2016 to July 2017. Malaria incidence showed a seasonal distribution, with an overall incidence rate estimated at 414.3 per 1000 person-years. In the active cross sectional surveys, we enrolled 2839, 2594 and 2337 participants respectively in September 2016, December 2016 and June 2017. Prevalence of malaria infection were respectively 41.5%, 43.5% and 32.3% in September 2016, in December 2016 and June 2017. Multivariate analysis showed that girls seemed to have a lower risk of malaria infection (OR = 0.86; 95% CI = 0.79 - 0.95; p = 0.004). The risk of malaria infection was significantly lower in third survey (June 2017) at the beginning of the rainy season (OR = 0.69; 95% CI = 0.6 - 0.8; p < 0.001) compared to the first survey (September 2016) which was performed during the rainy season. Children aged 6 to 59 months had a higher risk of malaria infection compared to those aged 10 to 17 years (OR = 0.58; 95% CI = 0.51 - 0.66).ConclusionMalaria burden remains high in this region of Burkina Faso despite substantial efforts made in malaria control during this current decade. Children under 5 years old were subject of malaria burden in this setting. This results reinforce the urgent need to develop alternative control strategies to complement those already existing.


2016 ◽  
Vol 1 (2) ◽  
Author(s):  
Eti Kurniawati

<p>Ascariasis incidence in children under five in the region work of Puskesmas Olak Kemang still a health problem that needs to be addressed, with a percentage of 51.0% is higher than in other wilayh. The disease is not lethal but can undermine the health of the human body so that the resulting decline in nutritional status, decreased intelligence and brain power or immune health in children.</p><p>               This research is a quantitative study using descriptive analytic method with cross sectional study design that aims to determine the relationship between the independent variables and the dependent variable. The population in this research that all children under five in the area of Puskesmas Olak Kemang, samples in this study were 75 children under five. Data were analyzed using analysis Univariate and Bivariate analysis with Chi-Square Test.</p><p>               The results showed that 78.0% of mothers of children under five who are not air personal hygiene, 60.4% of mothers of children under five unusual CTPS, 82.1% of respondents who did not state house meliliki latrine / WC. The results of the bivariate analysis showed that there was a significant relationship between personal hygiene (p-value = 0.000), customs CTPS (p-value = 0.001), latrine ownership (p-value = 0.000) with the incidence of intestinal worms in Puskesmas Olak Kemang Jambi.</p><p>               In connection with the results obtained, that the danger of de- worming is dependent on the cleanliness of his mother in serving as personal hygiene, CTPS and Owners toilets in every home. Thus the researchers suggested that the health center may be able to provide information to the public education about the dangers of de- worming to create a healthy society.</p><p> </p>Keyword                     :  Behavior, Children Events


1970 ◽  
Vol 19 (4) ◽  
pp. 3078-3084
Author(s):  
Chukwuemeka Kenechukwu Jude ◽  
Agozie Ubesie Chukwunedum ◽  
Kunle Obidike Egbuna

Background: Malnutrition (under and overnutrition) presents significant threats to child health. The co-existence of under and overnutrition in a population is increasingly being described in the literature .Objective: To identify the prevalence of malnutrition among under-five children in Enugu metropolis.Methods: A cross-sectional study of pre-primary school children conducted from January to May 2016. using stratified sampling technique. Caregiver-administered questionnaire was used to obtain relevant information. Weights and heights were measured using a standard weight scale and stadiometer/ length mat respectively. Wasting, stunting, overweight and obesity were determined based on the recommended WHO Growth Standard. Data analysis was done with SPSS version 20.0. The associations between nutritional status on one hand, and categorical variables such as age grouping, sex, socio-economic status, and maternal educationwere determined using chi square. . P-value < 0.05 were reported as statistically significant.Results: Eighteen (2.4%) and 26 (3.5%) subjects were wasted and stunted respectively. Eleven (1.5%) subjects were overweight while another 11(1.5%) subjects were obese. Risk factors for undernutrition were maternal education and low socioeconomic class while risk factor for overnutrition was upper socioeconomic class..Conclusion: There is a low rate of malnutrition in the area of study. However, sustained efforts must continue to prevent further rise and possibly eliminate the scourge of malnutrition.Keywords: Malnutrition, Nigeria.


2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Beatriz Galatas ◽  
Alfredo Mayor ◽  
Himanshu Gupta ◽  
Núria Balanza ◽  
Ihn Kyung Jang ◽  
...  

Abstract Background An ultrasensitive malaria rapid diagnostic test (RDT) was recently developed for the improved detection of low-density Plasmodium falciparum infections. This study aimed to compare the diagnostic performance of the PfHRP2-based Abbott Malaria Ag P. falciparum ultrasensitive RDT (uRDT) to that of the conventional SD-Bioline Malaria Ag P. falciparum RDT (cRDT) when performed under field conditions. Methods Finger-prick blood samples were collected from adults and children in two cross-sectional surveys in May of 2017 in southern Mozambique. Using real-time quantitative PCR (RT-qPCR) as the reference method, the age-specific diagnostic performance indicators of the cRDT and uRDT were compared. The presence of histidine-rich protein 2 (HRP2) and Plasmodium lactate dehydrogenase (pLDH) antigens was evaluated in a subset from dried blood spots by a quantitative antigen assay. pfhrp2 and pfhrp3 gene deletions were assessed in samples positive by RT-qPCR and negative by both RDTs. Results Among the 4,396 participants with complete test results, the sensitivity of uRDTs (68.2; 95% CI 60.8 to 74.9) was marginally better than that of cRDTs (61.5; 95% CI 53.9 to 68.6) (p-value = 0.004), while the specificities were similar (uRDT: 99.0 [95% CI 98.6 to 99.2], cRDT: 99.2 [95% CI 98.9 to 99.4], p-value = 0.02). While the performance of both RDTs was lowest in ≥ 15-year-olds, driven by the higher prevalence of low parasite density infections in this group, the sensitivity of uRDTs was significantly higher in this age group (54.9, 95% CI 40.3 to 68.9) compared to the sensitivity of cRDTs (39.2, 95% CI 25.8 to 53.9) (p-value = 0.008). Both RDTs detected P. falciparum infections at similar geometric mean parasite densities (112.9  parasites/μL for uRDTs and 145.5 parasites/μL for cRDTs). The presence of HRP2 antigen was similar among false positive (FP) samples of both tests (80.5% among uRDT-FPs and 84.4% among cRDT-FPs). Only one false negative sample was detected with a partial pfhrp2 deletion. Conclusion This study showed that the uRDTs developed by Abbott do not substantially outperform SD-Bioline Pf malaria RDTs in the community and are still not comparable to molecular methods to detect P. falciparum infections in this study setting.


2016 ◽  
Vol 2016 ◽  
pp. 1-11 ◽  
Author(s):  
David Z. Munisi ◽  
Joram Buza ◽  
Emmanuel A. Mpolya ◽  
Safari M. Kinung’hi

In Tanzania,Schistosoma mansoniis of great public health importance. Understanding the prevalence and infection intensity is important for targeted, evidence-based control strategies. This study aimed at studying the prevalence, intensity, and risk factors ofS. mansoniamong schoolchildren in the study area. A cross-sectional study was conducted in Busanga and Kibuyi villages. Sampled 513 schoolchildren provided stool specimens which were examined using kato-katz method. Pretested questionnaire was used to collect sociodemographic data and associated risk factors. The prevalence ofS. mansoniinfection was 84.01%, with geometric mean egg intensity of 167.13 (95% CI: 147.19–189.79) eggs per gram of stool (epg). Other parasites detected wereAscaris lumbricoides(1.4%) and hookworms (1.4%). The geometric mean infection intensity in Busanga and Kibuyi were 203.70 (95% CI: 169.67–244.56) and 135.98 (95% CI: 114.33–161.73) epg, respectively. Light, moderate, and heavy infection intensities were 34.11%, 39.91%, and 25.99%, respectively. Village of residence, parent’s level of education, toilet use, and treatment history were predictors of infection. The high prevalence and infection intensity in this study were associated with village, parent’s level of education, inconsistent toilet use, and treatment history. To control the disease among at-risk groups, these factors need to be considered in designing integrated schistosomiasis control interventions.


2020 ◽  
Vol 7 (1) ◽  
pp. 16
Author(s):  
Nita Pujianti ◽  
Lia Anggraini

ABSTRAKPneumonia merupakan penyebab banyak kematian balita di dunia. Selama tahun 2016 terdapat 568.146 (65,27%) jumlah kasus pneumonia pada balita yang ada di Indonesia. Berdasarkan data Dinas Kesehatan Provinsi Kalimantan Selatan tercatat kasus pneumonia tahun 2017 sebesar 66,52%, data tertinggi pada Puskesmas Beruntung Raya dengan angka 105 kasus (10,80%) di tahun 2017. Tujuan penelitian ini adalah untuk menganalisis faktor-faktor yang berhubungan dengan kepatuhan penggunaan antibiotika pada orang tua pasien anak yang terdiagnosa pneumonia di wilayah kerja Puskesmas Beruntung Raya serta menganalisa faktor yang paling dominan mempengaruhi. Penelitian ini menggunakan rancangan observasional analitik melalui pendekatan cross sectional. Populasi dalam penelitian ini adalah semua orang tua yang memeriksakan anaknya dalam satu tahun terakhir di Puskesmas Beruntung Raya. Sampel dalam penelitian ini berjumlah 77 responden ditentukan dengan teknik purposive sampling dan berlangsung selama 3 (tiga) bulan. Analisa data menggunakan uji chi square dan regresi logistik biner dan kuisioner sebagai Instrumen penelitian. Hasil penelitian menunjukkan bahwa terdapat hubungan antara kedisiplinan (p-value= 0,001), sugesti sembuh (p-value= 0,012), dan komunikasi (p-value= 0,025). Variabel kedisiplinan merupakan yang paling berpengaruh dominan terhadap kepatuhan penggunaan antibiotika, sehingga pasien yang disiplin lakan lebih patuh dalam meminum obat antibiotika daripada pasien yang tidak disiplin.Kata-kata kunci: Kepatuhan, pneumonia, kedisiplinan, sugesti sembuh, komunikasiABSTRACTPneumonia is the cause of many under-five deaths in the world. During 2016 there were 568,146 (65.27%) of the number of pneumonia cases in children under five in Indonesia. From the data of the South Kalimantan Provincial Health Office recorded pneumonia cases in 2017 amounted to 66.52%, the highest data in Beruntung Jaya Community Health Center with a number of 105 cases (10.80%) in 2017. The purpose of this study was to analyze the factors related by adhering to the use of antibiotics in the parents of pediatric patients with diagnosed with pneumonia in the work area of Beruntung Jaya Community Health Center and analysis the most dominant factor influencing. This study uses an observational analytic design through a cross sectional approach. The population in this study were all parents who had their children examined in the past year at Beruntung Raya Health Center. The sample in this study amounted to 77 respondents determined by purposive sampling technique and lasted for 3 (three) months. Data analysis using chi square test and binary logistic regression and questionnaires as research instruments. The results showed that there was a relationship between discipline (p-value= 0.001), recovery suggestions (p-value= 0.012), and communication (p-value= 0.025). Disciplinary variable is the most dominant influence on adherence to the use of antibiotics, so that disciplined patients are more obedient in taking antibiotic drugs than patients who are not disciplined.Key words: Compliance, pneumonia, discipline, healing suggestion, communication


2020 ◽  
Vol 7 (1) ◽  
pp. 28
Author(s):  
Kasman Kasman ◽  
Nuning Irnawulan Ishak

ABSTRAKSetiap anak mengalami episode serangan diare rata-rata 3,3 kali setiap tahun. Lebih kurang 80% kematian terjadi pada anak berusia kurang dari dua tahun. Penyakit diare merupakan salah satu penyakit yang banyak terjadi di Kota Banjarmasin. Penyebabnya diduga karena Kondisi sanitasi lingkungan yang tidak baik. Penelitian ini bertujuan untuk menganalisis penggunaan jamban terhadap kejadian diare pada anak balita di Kota Banjarmasin. Rancangan penelitian ini menggunakan desain cross-sectional. Populasi penelitian adalah seluruh anak balita yang ada di Kota Banjarmasin sebanyak 54.746 balita. Teknik penarikan sampel secara multistage sampling dengan jumlah sampel sebanyak 188 balita. Pengumpulan data dilakukan pada Bulan Juni sampai Agustus 2018 dengan wawancara langsung pada responden menggunakan kuesioner. Analisis data menggunakan uji statistik Chi Square. Hasil penelitian ini menunjukkan bahwa terdapat 22,9% anak balita yang menderita diare. Sebagian besar (97,9%) responden telah memiliki Jamban dengan jenis jamban menggunakan tangki septic 94,6%. Terdapat 19% jamban dengan kondisi yang tidak baik. Terdapat hubungan yang bermakna antara kepemilikan jamban (p-value=0,038) dan kondisi jamban (p-value =0,000) terhadap kejadian Diare pada Balita di Kota Banjarmasin. Diharapkan kepada masyarakat untuk memperhatikan kebersihan jamban.Kata-kata kunci : Diare, Balita, Penyakit infeksi, JambanABSTRACTEach child experiences episodes of diarrhea attack an average of 3.3 times each year. Approximately 80% of deaths occur in children aged less than two years. Diarrhea is one of the many diseases that occur in Banjarmasin. The cause is thought to be due to poor environmental sanitation. This study aims to analyze the use of latrines on the incidence of diarrhea in under-five children in Banjarmasin. The design of this study used a cross-sectional design. The study population was all toddlers in Banjarmasin of 54,746 toddlers. The sampling technique was multistage sampling with a total sample of 188 toddlers. Data collection was conducted from June to August 2018 with an interview with the respondent directly using a questionnaire. Data analysis using Chi-Square statistical tests. The results of this study indicate that there were 22.9% of children under five suffering from diarrhea. Most (97.9%) of respondents have had latrines in the type of latrine using a 94.6% septic tank. There is a significant relationship between latrine ownership (p-value= 0.038) and latrine condition (p-value= 0,000) to the incidence of diarrhea in children under five in Banjarmasin City. It is expected the public to pay attention to hygiene latrine.Keywords: Diarrhea, under-five children, infectious diseases, latrines


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