scholarly journals COVID- 19 Infections with and without Co-morbidities and Clinical Outcome

Author(s):  
Beenish Ghafar ◽  
Urooj Bhatti ◽  
Shehmeen Khan ◽  
Afsheen Abro ◽  
Rubina Ahmedani ◽  
...  

Aim: To evaluate the clinical outcomes and severity of disease in COVID-19 patients presenting with and without comorbidities.  Study Design: Cross-sectional study. Place and Duration: ICUs, wards of Jinnah Postgraduate Medical Center Karachi from March, to June 2021. Methodology: The enrolled patients diagnosed with COVID-19 ie according to the provisional directions given by WHO, were assessed for clinical outcomes. Comorbidities were determined based on patients self-report on admission.   Results: Total 200 COVID patients were enrolled in the study, out of them 179 were with comorbidities like type 2 Diabetes mellitus, hypertension, cardiac disorders and  asthma, while 21 COVID patients were with no co morbidity. In present study (n=200), 55.5% were belonging to the age group more than fifty five years old, there were 50.5% males and 29.5% patients came in the month of June 2021. There were 84% hypertensive, 54% were diabetic, 10% were Ischemic Heart Disease and 5% were Asthmatic patients.  Clinical outcomes, i.e., pneumothorax, pulmonary embolism, Myocardial Infarction,   septic shock, heart failure, Disseminated Intravascular Coagulation was compared  regarding associated co-morbidities at the time of admission, p-value was <0.01 and  x2=20.15 . Conclusion: COVID patients with comorbidities are more at risk of developing worst clinical outcomes.

Hypertension ◽  
2020 ◽  
Vol 76 (Suppl_1) ◽  
Author(s):  
José Martín Alanís Naranjo ◽  
Gabriela Olguín Contreras ◽  
Cristo Raymundo Ibarra Jaimes

Introduction: The world is currently suffering from the outbreak of a pandemic caused by the SARS-CoV-2 coronavirus, which causes the disease called COVID-19. This disease was reported for the first time in Wuhan, Hubei Province, China, on December 31, 2019. Hypertension, diabetes and cardiovascular disease are common among patients with COVID-19. In Mexico, information on the association between COVID-19 and hypertension is scarce. Methods: This investigation was a descriptive, observational and cross-sectional study that included patients over 18 years of age who had been hospitalized with laboratory-confirmed COVID-19 between April 6, 2020, and May 6, 2020, and exhibited chest X-ray abnormalities (ground-glass opacity, interstitial alterations and/or multilobar infiltrate). Severity of pneumonia (severe vs. nonsevere) at the time of admission was defined using the community-acquired pneumonia guidelines of the American Thoracic Society (ATS). Results: Information was collected from 89 patients with COVID-19 pneumonia, 34 of whom (38.2%) were hypertensive. When studying risk factors in hypertensive patients and their degree of statistical association with risk of mortality, only the severity of pneumonia stood out. The association between severe pneumonia and mortality was statistically significant (OR: 10.9, CI 1.19-99.6, p value = 0.034). Conclusions: Severity of pneumonia upon admission can be regarded as a marker of adverse clinical outcome in hypertensive COVID-19 patients. Among hypertensive COVID-19 patients, in-hospital mortality was high (68%); such mortality was higher in our study than has been reported in other series worldwide.


2019 ◽  
Vol 10 (1) ◽  
pp. 17-23
Author(s):  
Awaliyah Ulfah Ayudytha Ezdha ◽  
Ummu Habibah ◽  
Dwi Elka Fitri

ABSTRACT The hospital as a provider of health services in the form of maintaining and improving health and aims to achieve optimal health status for the community. One indicator of the quality of nursing services is whether the nursing services provided are satisfying the patient or not. One of the roles performed by nurses is to carry out health education in discharge planning for patients in the inpatient room. Health education is very important to be carried out by a nurse. The purpose of this study was to analyze the factors related to the implementation of health education by nurses in the Inpatient at PMC Hospital. The research design used is a quantitative method with analytic cross-sectional study design. This research was conducted at Pekanbaru Medical Center Hospital with a sample of 35 nurses on duty at the hospital according to inclusion criteria. From the results of the study found factors related to the implementation of health education by nurses in the inpatient room of the PMC Hospital : Length of Work (p value 0.010), Training attended (p value = 0,000) and Level of Knowledge (p value = 0.002). This means that factors related to the implementation of health education by nurses must be maintained and considered by management to improve the implementation of health education by nurses so that the quality of service and satisfaction can be improved.


2019 ◽  
Author(s):  
Sana Ullah ◽  
Siham Sikander ◽  
Mudassar Mushtaq Jawad Abbasi ◽  
Syed Aftab Rahim ◽  
Babar Hayat ◽  
...  

Abstract Background Prevalence of smoking is on the rise and its harmful effects on every organ of body are well known. Smoking is a growing concern due to adverse effects on health, its association with academic performance is not well studied. Objectives This study aims to assess the prevalence of smoking among undergraduate students of age 18-24 years in a public sector university of Islamabad, association between smoking and academic performance and also to assess the reasons of smoking initiation among undergraduate students. Methods The study included 500 undergraduate students. A self-report structured questionnaire was used to assess smoking, dietary habits, physical activity, parent’s smoking, friend’s smoking, time spent on mobile and TV and academic performance for collection of data. Logistic regression was used for association between smoking and academic performance. Results Results of study show that 112/500 (22.4%) students were smokers among them 93/112 (34.6%) were males and 19/112 (8.2%) were females. The mean age of study participants was 21.50 years (SD: 1.72. Prevalence of smoking was higher in students belonging to rural areas 23.5% to that of urban areas 21.9%. Three major reasons of smoking initiation; 25% students stated peers and friends, 21% stated easy availability while 14% said it was fun and enjoyment they started smoking. High academic performance was found to be inversely proportional to student’s smoking; at p-value 0.000 smokers had 2.5 (1.77, 3.74) odds of lower academic performance, boys having 2.17 (1.56, 3.03) odds of lower academic performance in last semester exams. Conclusion Findings highlighted extensive cigarette smoking among undergraduate students of Islamabad. Smoking is significantly and negatively associated with academic performance.


2019 ◽  
Vol 7 (14) ◽  
pp. 2246-2250
Author(s):  
Saba Jassim Hamdan ◽  
Zaid Al-Attar ◽  
Imad Hashim

BACKGROUND: Montelukast (Singulair) is a cysteinyl leukotriene receptor antagonist, used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergic rhinitis and asthma, also used for exercise-induced bronchospasm. AIM: This study was performed to determine the prevalence of Montelukast use as an add-on therapy among Iraqi asthmatic patients on treatment. Comparing the effectiveness of regimens with and without montelukast. METHODS: This descriptive cross-sectional study was carried out on 73 Iraqi asthmatic patients on treatment of both sexes with age range (18-60) years old, attending Al-Kindy Teaching Hospital and Al-Zahraa Centre of Asthma and Allergy, Baghdad, for the period between February and March 2017. A questionnaire was specifically prepared to meet the objectives and was used to collect the data of the study. RESULTS: There was a significant statistical reduction of frequency in asthmatic attacks after Montelukast treatment (p-value < 0.05). Out of 73 patients, 39 were males, and 34 were females, 46 were jobless, 37 were married, 63 were urban residents, 63 were educated. Prevalence of exacerbation factors was as following: infection was found in 60.3% of the patients, exercise in 57.5%, dust in 72.6%, smoking in 60.6%, food in 24.7%, others (stress, perfumes) in 20.5%. The prevalence of Montelukast use in this study was 46% (34 patients). Out of 34 patients using Montelukast, 28 were using inhaled salbutamol, 5 were using oral salbutamol, 15 were using inhaled corticosteroids, 9 were using systematic corticosteroids, 2 were using xanthines, and 6 were using ketotifen. CONCLUSION: Montelukast was used as add-on therapy with the inhaled corticosteroids to reduce the required dose of inhaled corticosteroids also the use of Montelukast lead to reduced number of exacerbations which will be reflected on the use of inhaled salbutamol and systematic corticosteroids. Also, Montelukast was superior to xanthines and ketotifen as an add-on therapy.


Author(s):  
Nadia Shekari ◽  
Hassan Khodadadi ◽  
Ahmad Reza Sayadi ◽  
Mohammad Asadpour

Background: Failure to observe hygienic principles and making minor cuts with scissors and razors while applying makeup may lead to the transmission of diseases of blood origin. The aim of this study was to investigate the knowledge and attitude of female hairdressers in Rafsanjan regarding the prevention of Blood-borne diseases and its relationship with demographic characteristics in 2019-2020. Methods: This cross-sectional study was performed in all hairdressing salons in Rafsanjan that had official activities, by census (201 hairdressers). The tool for measuring knowledge and attitude was a researcher-made questionnaire that was completed as a self-report. The questionnaires were anonymous and coded and included demographic information, awareness and attitude. Data were entered into SPSS software version 18 and reported by indices of Dispersion indices, frequency distribution and Pearson correlation coefficient. Results: The average knowledge and attitude of hairdressers about Blood-borne diseases were 57.95 ± 5.11 and 57.95 ± 11.35, respectively. There was a statistically significant relationship between the mean score of knowledge and attitude of the research samples with the level of literacy (p value = 0.001). Most of the research samples mentioned that there is a vaccine to prevent hepatitis C disease and it was believed that covering the needle head after use has no effect on Blood-borne diseases. Conclusion: Considering the average level of knowledge of hairdressers, it is suggested that more effective training courses to increase the knowledge of hairdressers using different training methods in order to make more effectiveness of health programs.


Author(s):  
Prakash Behere ◽  
Mangesh Rathod ◽  
Debolina Chowdhury ◽  
Amit Nagdive ◽  
Aniruddh Prakash Behere ◽  
...  

Introduction: An important component in the management of schizophrenia is insight. Schizophrenia patients that lack insight have poor clinical outcomes. Chronic patients of chronic schizophrenia lacking insight more often require hospitalisation than those recognising their illness. Poor insight is a good indicator of poor compliance and can predict the prognosis of any psychiatric patient including schizophrenia. Aim: This study was aimed at contrasting the gain in insight after treatment among various sub-groups of patients with schizophrenia. Materials and Methods: A cross-sectional study was conducted at the Acharya Vinobha Bhave Rural Hospital, Wradha, Maharashtra. The sample size was collected for a period of 1 year, during which all the patients admitted to the psychiatry ward were screened, of which 100 eligible patients with schizophrenia were identified using prespecified inclusion and exclusion criteria. Patients of both sexes aged above 18 years and attendants that provided consent were included in the study. The Schedule for Assessment of Insight Scale (SAI) was used to determine the patient’s level of insight. The proportion of patients with distinct socio-demographic characteristics, clinical profile, psychiatric diagnosis and SAI scores were calculated. A paired t-test was used for elaborating the results. The p-value <0.05 was considered significant. Results: The changes in insight scores from the time of admission (4.15) to the time of discharge (9.28) were statistically significant and similar in both males and females and also results are statistically significant according to marital status. Significant improvement was seen in patients irrespective of their employment status or their educational status. Conclusion: This study showed that the insight changes as the patient improves during the hospital stay. This study highlights that poor insight is commonly seen in psychotic patients and the treatment considerably improves their insight.


2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Vinh Nguyen Nhu ◽  
Pham Le An ◽  
Niels H. Chavannes

Background. FeNO has been used as a marker for Th2-mediated airway inflammation in asthma. There is evidence which recommends the use of this biomarker in asthma management. Little is known about whether the FeNO test alone or in combination with the ACT score can reflect asthma control in Vietnamese patients. Materials and Methods. A cross-sectional study was conducted in asthmatic patients (≥18 years old) recruited at the University Medical Center, Ho Chi Minh City, Vietnam from March 2016 to March 2017. Asthma control levels were assessed following the GINA 2017 guidelines, and FeNO was measured by a Niox Mino device. FeNO cut-offs predicting asthma control status were determined using the ROC curve analysis. The combination of FeNO and ACT was investigated in detecting well-controlled and uncontrolled asthma. The results of the study are as follows: 278 patients with 68% females, mean age of 44 years, and mean asthma duration of 10 years were analyzed. All patients were treated following step 2 to 4 of GINA guidelines. Mean (SD) FeNO was 30.6 (24) ppb. Patients with uncontrolled (16%), partly controlled (29%), and well-controlled asthma (55%) had a median (IQR) FeNO of 50.0 (74), 25.0 (23), and 21.0 (22.3) ppb, respectively, and the mean of FeNO in the uncontrolled group was significantly higher than that in other groups (p<0.001). The area under the ROC curve (AUC) for FeNO detecting uncontrolled asthma was 0.730 with an optimal cut-off point of FeNO > 50 ppb, and this AUC increased to 0.89 when combining FeNO and ACT. The AUC for FeNO detecting well-controlled asthma was 0.601 with an optimal cut-off point of FeNO <25 ppb and this AUC increased to 0.78 if combining FeNO and ACT. Conclusions. FeNO can predict asthma control status with an estimated cut-off point of <25 ppb for well-controlled and >50 ppb for uncontrolled asthma. The combination of FeNO and ACT provides better information regarding asthma control than FeNO alone, and this combination is useful to predict asthma control statuses in asthmatic patients in Viet Nam.


Infection ◽  
2021 ◽  
Author(s):  
Jean Claude Dejon-Agobé ◽  
Ayôla A. Adegnika ◽  
Martin P. Grobusch

Abstract Background Schistosomiasis is a parasitic disease affecting the blood cell. As a chronic disease, schistosomiasis particularly impacts on the human host’s haematological profile. We assessed here the impact of urogenital schistosomiasis on the full blood counts (FBC) as proxy diagnostic tool for schistosomiasis. Methods A cross-sectional study was conducted among school children living in Lambaréné, Gabon. Schistosomiasis status was determined using urine filtration technique. EDTA blood samples were analysed using a Pentra ABX 60® analyzer. Results Compared to their infection-free counterparts, school children infected with Schistosoma haematobium displayed an altered FBC profile, with changes in all three blood cell lines. Adjusted for praziquantel intake, soil-transmitted helminthic infections and Plasmodium falciparum infection status, schistosomiasis was independently associated with a decreasing trend of mean haemoglobin (β = − 0.20 g/dL, p-value = 0.08) and hematocrit (β = − 0.61%, p-value = 0.06) levels, a lower mean MCV (β = − 1.50µm3, p-value = 0.02) and MCH (β = − 0.54 pg, p-value = 0.04), and higher platelet (β = 28.2 103/mm3, p-value = 0.002) and leukocyte (β = 1.13 103/mm3, p-value = 0.0003) counts, respectively. Conclusions Schistosomiasis is associated with a characteristic FBC profile of schoolchildren living in Lambaréné, indicating the necessity to consider schistosomiasis as a single cause of disease, or a co-morbidity, when interpreting FBC in endemic areas.


2008 ◽  
Vol 19 (10) ◽  
pp. 685-688 ◽  
Author(s):  
L F B Filho ◽  
S A Nogueira ◽  
E S Machado ◽  
T F Abreu ◽  
R H De Oliveira ◽  
...  

The objective of this study was to describe the adherence to antiretroviral therapy (ART) among adolescents followed-up in Rio de Janeiro. This cross-sectional study included all adolescents (aged 10–19 years) followed at Instituto de Puericultura e Pediatria Martagão Gesteira and Hospital Universitário Clementino Fraga Filho. Adherence was determined by self-report (number of missed ART doses in three days prior to the interview). Adherence was categorized as taking ≥95% of the ARTs (adherent), or <95% (non-adherent). Variables related to demographics and treatment were evaluated and if P value ≤0.15, they were selected for a logistic regression analysis. One hundred and one adolescents were interviewed. The mean time on ART was 91 months and the mean adherence was 94% of this, 21 were non-adherent, and 80 adherent. The risk factors associated with non-adherence were: if the patient was not concerned about ART, odds ratio (OR) = 3.47 (95% confidence interval [CI] = 1.13–10.68); if they do not carry an extra dose of ART, OR = 6.63 (95% CI = 1.73–25.47); if a healthcare worker taught them how to take ART, OR = 0.27 (95% CI = 0.08–0.93). Adherence among adolescents was higher than expected. Factors associated with lack of adherence were: interviewees being unaware of ARTs and lack of commitment to the treatment. Interventions involving these factors must be evaluated.


Sign in / Sign up

Export Citation Format

Share Document