scholarly journals Haematological changes in Schistosoma haematobium infections in school children in Gabon

Infection ◽  
2021 ◽  
Author(s):  
Jean Claude Dejon-Agobé ◽  
Ayôla A. Adegnika ◽  
Martin P. Grobusch
Keyword(s):  
Blood Cell ◽  
School Children ◽  
Schistosoma Haematobium ◽  
Cross Sectional Study ◽  
P Value ◽  
Urogenital Schistosomiasis ◽  
Cross Sectional ◽  
Co Morbidity ◽  
Haematological Profile ◽  
The Impact

Abstract Background Schistosomiasis is a parasitic disease affecting the blood cell. As a chronic disease, schistosomiasis particularly impacts on the human host’s haematological profile. We assessed here the impact of urogenital schistosomiasis on the full blood counts (FBC) as proxy diagnostic tool for schistosomiasis. Methods A cross-sectional study was conducted among school children living in Lambaréné, Gabon. Schistosomiasis status was determined using urine filtration technique. EDTA blood samples were analysed using a Pentra ABX 60® analyzer. Results Compared to their infection-free counterparts, school children infected with Schistosoma haematobium displayed an altered FBC profile, with changes in all three blood cell lines. Adjusted for praziquantel intake, soil-transmitted helminthic infections and Plasmodium falciparum infection status, schistosomiasis was independently associated with a decreasing trend of mean haemoglobin (β = − 0.20 g/dL, p-value = 0.08) and hematocrit (β = − 0.61%, p-value = 0.06) levels, a lower mean MCV (β = − 1.50µm3, p-value = 0.02) and MCH (β = − 0.54 pg, p-value = 0.04), and higher platelet (β = 28.2 103/mm3, p-value = 0.002) and leukocyte (β = 1.13 103/mm3, p-value = 0.0003) counts, respectively. Conclusions Schistosomiasis is associated with a characteristic FBC profile of schoolchildren living in Lambaréné, indicating the necessity to consider schistosomiasis as a single cause of disease, or a co-morbidity, when interpreting FBC in endemic areas.

scholarly journals Assessing the usage of screen based media and screen time among adolescents in Mysuru: a cross-sectional study

2020 ◽  
Vol 7 (6) ◽  
pp. 2233
Author(s):  
G. Shwetha ◽  
Sunil Kumar Doddaiah ◽  
Anil S. Bilimale ◽  
M. R. Narayana Murthy
Keyword(s):  
School Children ◽  
Screen Time ◽  
Statistical Significance ◽  
Structured Interview ◽  
Cross Sectional Study ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Total Study Population ◽  
The Impact

Background: Media is one of the important parts of the life of school children, especially those aged between 13 to 17 years. It has both positive and negative impacts on children. It affects both physical and mental health; there will be a prominent impact on their studies also. Nowadays everyone has the accessibility of television, mobile, etc in India. This study mainly aims to assess the impact of screen-based media (SBM) and screen time among middle adolescents and the association of socio-demographic status with the usage of SBM.Methods: A cross-sectional study was conducted in Government and Private schools of Mysuru district from November to December 2019. The study included 180 school children between the age group of 13 to 17 years through simple random sampling. A semi-structured interview questionnaire was used.Results: Mobile formed the maximum used SBM. Out of the total screen time, time contributed by television 90.5%, mobile 95.6%, and both television and mobile 91.7% will be more followed by other SBM. The proportion of children having the screen time of maybe 3 hrs was found to be 25.6% and more than 3 hrs was 5.9% among the total study population. There is an association between SBM usage and the socio-demographic status i.e. age, type of family, father's education, and father occupation with the statistical significance of p value <0.05.Conclusions: According to the current study, there is a high proportion of school children using SBM. So, there is a need to create awareness regarding the use of SBM and its impact on children among parents, teachers, and children.

scholarly journals Haematological profile of chronic kidney disease in a mixed-ancestry South African population: a cross-sectional study

BMJ Open ◽  
2018 ◽  
Vol 8 (11) ◽  
pp. e025694 ◽  
Author(s):  
Cindy George ◽  
Tandi E Matsha ◽  
Rajiv T Erasmus ◽  
Andre P Kengne
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Blood Cell ◽  
Kidney Function ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Mixed Ancestry ◽  
Cross Sectional ◽  
Haematological Profile ◽  
Rbc Indices

ObjectivesThe objectives were to characterise the haematological profile of screen-detected chronic kidney disease (CKD) participants and to correlate the complete blood count measures with the commonly advocated kidney function estimators.MethodsThe current cross-sectional study used data, collected between February 2015 and November 2016, of 1564 adults of mixed-ancestry, who participated in the Cape Town Vascular and Metabolic Health study. Kidney function was estimated using the Modification of Diet in Renal Disease (MDRD) and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations. CKD was defined as estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m2, and anaemia as haemoglobin level <13.5 g/dL (men) and <12 g/dL (women).ResultsBased on the MDRD and CKD-EPI equations, the crude prevalence of CKD was 6% and 3%. Irrespective of the equation used, median red blood cell (RBC) indices were consistently lower in those with CKD compared with those without CKD (all p<0.0001). Despite not showing any significant difference in total white blood cell (WBC) count between the two groups, the number of lymphocytes were lower (p=0.0001 and p<0.0001 for MDRD and CKD-EPI, respectively) and neutrophil count (both p<0.0297) and the ratio of lymphocytes to neutrophil (both p<0.0001) higher in the CKD group compared with those without CKD; with the remaining WBC indices similar in the two groups. The platelet count was similar in both groups. Of the screen-detected CKD participants, 45.5% (MDRD) and 57.8% (CKD-EPI) were anaemic, with the prevalence increasing with increasing severity of CKD, from 37.2% (stage 3) to 82.4% (stages 4–5). Furthermore, CKD-EPI-estimated kidney function, but not MDRD, was positively associated with RBC indices.ConclusionThough it remains unclear whether common kidney function estimators provide accurate estimates of CKD in Africans, the correlation of their estimates with deteriorating RBC profile, suggests that advocated estimators, to some extent approximate kidney function in African populations.

scholarly journals Tinnitus: The Sound of Stress?

2018 ◽  
Vol 14 (1) ◽  
pp. 264-269 ◽  
Author(s):  
Patricia Ciminelli ◽  
Sergio Machado ◽  
Manoela Palmeira ◽  
Mauro Giovanni Carta ◽  
Sarah Cristina Beirith ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Progressive Increase ◽  
Cross Sectional Study ◽  
P Value ◽  
Cross Sectional ◽  
Mean Values ◽  
Subjective Tinnitus ◽  
Stress Symptoms ◽  
The Impact

Background: Emotional stress is frequently associated with otologic symptoms as tinnitus and dizziness. Stress can contribute to the beginning or worsening of tinnitus. Objective: The objective of the study is to evaluate the presence of stress symptoms in patients with chronic, subjective tinnitus, and correlate its presence to annoyance associated with tinnitus. Methods: This is a cross-sectional study. One hundred and eighty patients with chronic, subjective tinnitus were included. Patients answered the Tinnitus Handicap Inventory (THI) to evaluate the impact of tinnitus in the quality of life and answered the Lipp's inventory symptoms of stress for adults (ISSL). The data obtained was organized using Excel® 2010, mean values, linear regression and p-value were calculated. Results: Of the 180 patients included in the study, 117 (65%) had stress symptoms, 52 of the 117 (44%) were in the resistance phase and 23 of the 117 (20%) in the exhaustion phase, the remaining was in the alert phase. There was a clear progressive increase in stress as THI raised, with more impact of tinnitus in quality of life. Conclusion: The presence of stress symptoms, measured by ISSL was observed in most of our patients with chronic subjective tinnitus, specially in the resistance and exhaustion phases and it is directly associated with tinnitus annoyance.

scholarly journals THE IMPACT OF MEDICATION ADHERENCE ON HEALTH-RELATED QUALITY OF LIFE OF DIABETIC PATIENTS IN THE KINGDOM OF SAUDI ARABIA: FINDINGS FROM A CROSS-SECTIONAL STUDY

2020 ◽  
Vol 17 (34) ◽  
pp. 867-873
Author(s):  
Dhfer ALSHAYBAN ◽  
Royes JOSEPH
Keyword(s):  
Quality Of Life ◽  
Medication Adherence ◽  
Cross Sectional Study ◽  
P Value ◽  
Diabetic Patients ◽  
Health State ◽  
Cross Sectional ◽  
Related Quality ◽  
The Impact

Diabetes is a common chronic disease that is considered as one of the fastest-growing health problems in the world. Adherence to medications could be an important factor in reducing these complications and improving the quality of life. The purpose of this research was to assess the impact of treatment adherence on health-related quality of life in patients with type 2 diabetes. A multicenter cross-sectional study was carried out among 368 diabetes patients. General Medication Adherence Scale was used to assess the adherence level and EuroQol-5D to assess the quality of life. The results show that 19%, 21%, and 23% of patients had maintained low medication adherence due to patient’s intentional or unintentional behavior due to additional diseases or pills burden and due to financial constraints, respectively. Overall, 43% (n=162) participants had maintained high medication adherence, and 37% (n=138) had maintained low medication adherence to antidiabetic drugs. Nearly one-third (31%) of patients with high overall adherence had perfect health state in comparison with 4% among patients with low adherence. Further, the lower proportion (21%) of patients with high overall adherence had perfect health state in comparison with that among patients with low adherence (34%). In addition to the overall adherence, the association was statistically significant for the domains related to non-adherence due to the patient’s intentional or unintentional behavior (p-value 0.001) and non-adherence due to additional diseases or pills burden (p-value 0.001) after taking into account of socio-demographic and clinical characteristics. In conclusion, the findings suggest that the policymakers should establish an intervention to improve adherence to diabetic treatment, and thus improve the quality of life for the type 2 diabetic patients.

scholarly journals Impact of the Neuregulin rs35753505 C/T Polymorphisms on Neuregulin 1 Levels in Preterm Infants

2019 ◽  
Vol 7 (12) ◽  
pp. 1931-1934
Author(s):  
Bugis Mardina Lubis ◽  
Sjarif Hidajat Effendi ◽  
Ratna Akbari Ganie ◽  
Oke Rina Ramayani
Keyword(s):  
Preterm Infants ◽  
Cross Sectional Study ◽  
Enzyme Linked Immunosorbent Assay ◽  
P Value ◽  
Nucleotide Polymorphisms ◽  
Gene Encoding ◽  
Cross Sectional ◽  
Neuregulin 1 ◽  
Organ Systems ◽  
The Impact

BACKGROUND: Neuregulin (NRG) 1 plays an important role in the development of various organ systems in human. Single nucleotide polymorphisms rs35753505 C/Tof the gene encoding NRG1 evident as allele C and T with genotypes of CT, CC, and TT are believed to have an impact on NRG1 levels.AIM: To determine the impact of the NRGrs35753505 C/T polymorphisms on NRG1 levels in preterm infants.METHODS: A cross-sectional study was conducted from February to December 2018, whereas 48 eligible preterm infants with a gestational age of 32- < 37 weeks were enrolled. An umbilical cord blood specimen was collected for determination of NRG1 levels with enzyme-linked immunosorbent assay (ELISA) and NRG1 polymorphisms with polymerase chain reaction (PCR). Statistical analysis was performed with 95%CI and P value of < 0.05 was considered statistically significant.RESULTS: Median value of NRG1 levels (174.4 pg/ml) served as a cut off value. NRG 1 polymorphisms composed distribution of CC (31%), CT (42%), TT (27%) genotypes and distribution of C and T alleles were 52% and 48%. The median NRG1 levels in CC and CT genotypes were significantly lower compared to TT genotype (151.1 pg/ml vs 407.2 pg/ml, P = 0.005 and 159.1 pg/ml vs 407.2 pg/ml, P = 0.009). Subjects with C allele had significantly lower median NRG1 levels than T allele (151.1 pg/ml vs 407.2 pg/ml, P = 0.002). Subjects with CC and CT genotypes had higher risk to develop lower NRG1 levels compared to TT genotype (OR = 8.25, P = 0.016 and OR = 10.74, P = 0.005, respectively).CONCLUSION: Allele C is associated with lower NRG1 levels. Preterm infants with CC and CT genotypes pose a higher risk to have lower NRG1 levels.

scholarly journals Pattern analysis of S. haematobium infection and elimination in the area of Alsuki, Sudan

2021 ◽  
Vol 8 (3) ◽  
pp. 1059
Author(s):  
Rawia A. Abdelshafie ◽  
Abdalla I. Abdalla Mohamed
Keyword(s):  
Risk Factors ◽  
Statistical Analysis ◽  
Health Program ◽  
Pattern Analysis ◽  
Cross Sectional Study ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
The People ◽  
The Impact

Background: The aim of this study was to determine the current conditions of children of the selected area, for the purpose of measuring the new effective health program for schistosomiasis disease eliminations and obtain the prevalence intensity and risk factors of S. haematobium among school children in the study area.Methods: A descriptive cross-sectional study was used to screen school going children of all the ages from five randomly selected schools from Alsuki region. A statistical analysis derived from data formulated based on 1062 samples aged between 6 and 15 years attending the selected schools during the period testing within 6 months were enrolled.Results: The impact of health awareness program was measured usefully and the responded factor for reducing the Schistosomiasis diseases was significantly became less than (0.05). Therefore, the actual qualified fitting degree and applicability was significantly becoming (p value=0.001).Conclusions: This research concluded that the prediction of Schistosomiasis diseases due to the risk Ratio of the collected data for those who did not attended awareness over the people who attended program became (0.248).

Hematological alteration among visceral leishmaniasis patients attending in Western Tigrai, Ethiopia, 2018/2019: A cross-sectional study

2020 ◽  
Author(s):  
Gebremedhin Gebremichail ◽  
Brhane Tesfanchal ◽  
Getachew Belay ◽  
Gebreslassie Gebremariam ◽  
Gebreyohans Teklehaymanot ◽  
...  
Keyword(s):  
Visceral Leishmaniasis ◽  
Blood Cell ◽  
Hematological Parameters ◽  
Cross Sectional Study ◽  
P Value ◽  
Sectional Study ◽  
Control Groups ◽  
Cross Sectional ◽  
Red Cell Indices ◽  
Hematological Abnormalities

Abstract Background: Hematological abnormalities are common in visceral leishmaniasis patients, which is one of the main public health problems worldwide. The most common hematological abnormalities are anemia, leucopenia and thrombocytopenia. Therefore, this study aimed to assess the hematological alteration among visceral leishmaniasis patients attending Western Tigrai, Ethiopia, 2019. Method: Hospital based comparative cross sectional study was conducted from November 2018 to March 2019 in Western Tigrai, Ethiopia. A total of 100 Visceral Leishmaniasis patients and 100 control groups were included in this study. Blood was collected and analyzed by mindray BC-5800 hematology analyzer. Data was entered and analyzed using Statistical package for social science version 23. Student independent t-test was used for data analysis. P value <0.05 was considered as statistically significant at 95% confidence level. Result: From the total 100 visceral leishmaniasis patients the following abnormalities were reported: 96(96%) anemia, 95(95%) leucopenia, 92(92%) neutropenia, 73(73%) Lymphopenia, 45(45%) eosinopenia and 97(97%) had thrombocytopenia. Red blood cell, hemoglobin, hematocrit, red cell indices and platelet were significantly lower (p<0.05) in visceral leishmaniasis patients compared with the control groups. Similarly the total White blood cell, neutrophil, lymphocyte, eosinophil and basophil count were significantly lower (p<0.05) in visceral leishmaniasis patients compared with the control groups. Conclusion: The major changes in peripheral blood of patient with visceral leishmaniasis are reduced number of red blood cells, reduction in leukocytes and decreased platelet count. Visceral leishmaniasis patients presented with anemia, leucopenia and thrombocytopenia. So this finding indicates that visceral leishmaniasis causes alterations of hematological parameters. Key words: Amastigote, Anemia, Hematological Parameters, Promastigote, Visceral leishmaniasis, Ethiopia .

Prevalence and Associated Factors of Urinary Schistosomiasis among Basic School Children in the Akyemansa District, Ghana

2019 ◽  
pp. 1-10
Author(s):  
Albert Abaka-Yawson ◽  
Christian Hotorvi ◽  
Enos Amoako Oduro ◽  
Philip Apraku Tawiah ◽  
Solomon Sosu Quarshie ◽  
...  
Keyword(s):  
Risk Factors ◽  
School Children ◽  
Schistosoma Haematobium ◽  
Intervention Strategy ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Urinary Schistosomiasis ◽  
Multi Stage ◽  
Basic School ◽  
Associated Risk Factors

Background: Globally, urinary schistosomiasis has devastating implications on school children. It predisposes them to dysuria, haematuria among others which can negatively influence their academic performance. This study determined the prevalence and associated risk factors of urinary schistosomiasis among basic school children in the Akyemansa district.  Materials and Methods: A cross-sectional study design using multi-stage sampling was used to enroll 504 basic school children from six communities of the Akyemansa District into study. Structured questionnaires were used to gather information on risk factors. Urine samples were collected and microscopically examined for the presence of Schistosoma haematobium (SH) ova. The observed ova were then quantified as light or heavy. Results: Prevalence of SH infection among school children in Akyemansa District was 10.32% [95% CI: 7.80 -13.31%]. Out of 52 participants who were infected, 69.2% had light infection whilst the rest had heavy infection. Female participants were less likely to be infected with SH than males [OR=0.47; 95% CI: 0.23-0.97], children who do not stay by the river/stream were also less likely to be infected with SH compared to those who lived near waterbodies [OR=0.35; 95% CI: 0.17-0.72]. Additionally, participants who did not play around water bodies were also less likely to be infected with SH compared to those who did [OR=0.17; 95% CI= 0.04-0.71; p=0.015]. However, inhabitants of Kotokuom were more likely to be infected compared to those in Pawuda [OR=8.54; 95% CI: 1.91-38.27; p=0.005] Conclusion: The prevalence of urinary schistosomiasis among basic school children in the Akyemansa district was found to be 10.32% [95% CI: 7.80 -13.31%]. Gender, staying around river/ stream, playing at river/ stream and habitation of participants were significantly associated with the prevalence of Schistosoma haematobium infection. The study therefore recommends that periodic drug administration and a comprehensive intervention strategy should be designed and implemented to reduce schistosomiasis prevalence.

scholarly journals Assessment of the Impact of Mood on Food Intake and BMI Among Secondary Female Students in Al Madinah Almunawarah, KSA

2018 ◽  
Vol 3 (2) ◽  
Keyword(s):  
Body Weight ◽  
Dietary Intake ◽  
Negative Mood ◽  
Cross Sectional Study ◽  
Female Students ◽  
P Value ◽  
Food Diary ◽  
Cross Sectional ◽  
Lifestyle Questionnaire ◽  
The Impact

Introduction: Eating healthy is one of the essential things that should be taught at a young age. Obesity among adolescent or young girls is increasing dramatically. Psychological factors like mood swings can contribute to increased dietary intake and eventually to obesity. Aims: To explore the impact of mood on dietary intake and development of obesity Design: A cross-sectional study was conducted on a hundred female students aged from 13 to 15 years old. Students were selected randomly from three private secondary schools located in Al-Madinah. Students who matched the inclusion criteria were allowed to participate. A health and lifestyle questionnaire was distributed as well as a food diary to record their food consumption and mood over the upcoming three days (two school days and one weekend day). Weight and height were measured and BMI was obtained and compared to percentile BMI for age according to WHO. Results: A cross-sectional analysis determined the association between negative mood and intake of the following: calories: p value (0.02), fat: p value (0.01) and carbohydrates (0.01) respectively. Moreover, analysis also determined the association between BMI percentile (obese and overweight students) and intake of all of the following; fat (p=0.001), carbs (p=0.014) and kcal (p=0.006). Conclusion: Negative mood among students or adolescents could contributes to increase consumption of fat, carbs and energy and could lead to increasing body weight, compared to students with positive mood which could lead them to consume less fat, carbs and calories and then not effect body weight.

scholarly journals HUBUNGAN KEBIASAAN MENONTON TAYANGAN KEKERASAN DI TELEVISI DENGAN PERILAKU AGRESIF PADA ANAK USIA PRA SEKOLAH

2020 ◽  
Vol 8 (1) ◽  
pp. 91
Author(s):  
Andre Ratuela ◽  
Hendro Bidjuni ◽  
Sefti Rompas
Keyword(s):  
Aggressive Behavior ◽  
School Children ◽  
Violent Behavior ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
School Age Children ◽  
P Value ◽  
Cross Sectional ◽  
Study Approach ◽  
The Relationship

Abstract: Aggressive behavior is a physical or psychological action that is intentionally carried out to hurt another child, such as hitting, pushing, fighting, humiliating, insulting, spreading false or excusing issues. Violence is one of the issues affecting the practice of early childhood education. Purpose: To determine the relationship between the habit of watching violence on television and aggressive behavior in pre-school children. Method : this study used Descriptive analytic with cross sectional study  approach. 32 respondents of pre-school children participate in this study used total sampling technique. Data collection method used 2 quationnaire about the watching violance habbits on TV and aggressive behavior at child on pre-school. Date analysis used Spermen corelation test This. The Result of this study showed p value=0,04 with α<0,05. Conclusion: there was a relationship between watching violence on television with aggressive behavior in pre-school age children in GMIM Kindergarten Musafir Kleak. Suggestion: The results of this study recommend to provide benefits for parents in efforts to prevent the occurrence of violent behavior by children. Keywords: Watching Habits, Violent Impressions, Aggressive Behavior.Abstrak : Perilaku  agresif adalah  tindakan fisik atau psikologis yang secara sengaja dilakukan untuk menyakiti anak lain, seperti memukul, mendorong, berkelahi, mempermalukan, menghina, menyebarkan isu yang tidak  benar atau  mengucilkan. Kekerasan merupakan salah satu persoalan yang berpengaruh terhadap praktik pendidikan anak usia dini. Tujuan: Untuk mengetahui hubungan kebiasaan menonton tayangan kekerasan di televisi dan perilaku agresif pada anak pra sekolah di TK GMIM Musafir Kleak. Metode Penelitian : Penelitian ini menggunakan teknik Deskriptif analitik dengan pendekatan Cross Sectional. Sampel dalam penelitian ini menggunakan 32 responden dengan teknik total sampling. Pengumpulan data menggunakan 2 kuesioner yaitu kebiasaan menonton tayangan kekerasan di TV dan perilaku agresif pada anak pra-sekolah. Penelitian ini menggunakan uji Spearmen dan Hasil dari penelitian ini menunjukkan nilai p=0,04 yang berarti bahwa nilai α<0,05. Kesimpulan: Ada hubungan yang erat antara  menonton tayangan kekerasan di televisi dengan perilaku agresif pada anak usia pra sekolah di TK GMIM Musafir Kleak. Hasil penelitian ini diharapkan dapat memberikan manfaat bagi orang tua dalam upaya pencegahan terjadinya perilaku kekerasan oleh anak.Kata Kunci: Kebiasaan Menonton, Tayangan Kekerasan, Perilaku Agresif

Sign in / Sign up

Export Citation Format

Share Document