Antioxidant Studies of Thiazole Ring Bearing Chalcone Derivatives
2021 ◽
pp. 355-359
Keyword(s):
Oxidative stress is one of the common problems seen in a variety of diseases. Chalcones and in particular heteroaryl chalcones had reported with promising antioxidant activities. Hence, in the present work, we reported the antioxidant activity of twenty thiazole ring bearing chalcone derivatives (1-20). Among the tested compounds, compounds 17, 19 and 20 containing 2-pyridinyl, 3-pyridinyl and 2-thiazolyl scaffolds showed superior antioxidant activity than the standard with their IC50 values 4±1µg/mL, 3±1 µg/mL and 5±1 µg/mL respectively. The compound 19 is an interesting lead for the development of newer antioxidant agents.
2018 ◽
Vol 11
(3)
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pp. 194
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2021 ◽
Vol 15
(1)
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2016 ◽
Vol 2016
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pp. 1-17
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2017 ◽
Vol 10
(2)
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pp. 343
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2009 ◽
Vol 64
(3-4)
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pp. 197-200
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