Mining Associated Malaria Epidemics

Tropical alluvial gold and gem miners are often an especially at-risk population for malaria infection. Geographical areas of mining-associated malaria epidemics in the recent past include Southeast Asia (Cambodia, Thailand, and Myanmar); the Amazon basin (Brazil, French Guyana, Suriname, Columbia, and Peru); and tropical Africa. Mobile populations of young adult men engaged in the hard labor of mining may experience severe malaria especially if they lack preexisting immunity and are irregularly consuming antimalarial drugs. Particular problems occur because much of this informal mining activity is illegal and done in isolated areas without access to health services and with evidence of emerging antimalarial drug resistance. Concentrating vulnerable populations in an ecologically disturbed landscape is often conducive to epidemics, which can then spread as these highly mobile workers return to their homes. Mining-associated malaria endangers malaria elimination efforts and miners need to be addressed as a group of particular concern.

‘Smelling’ diasporic: bargaining interactions and the problem of politeness

While post-migrant generation Moroccans from Europe often are able to converse competently enough in Moroccan languages to bargain in shops during visits to Morocco, many report that they are not given the ‘local’, ‘right’ prices because they are ‘smelled’ as outsiders. During fieldwork following these diasporic visitors in Morocco, several participants strategically shopped for goods with a ‘local’ friend or family member who might negotiate on their behalf for the ‘right’ price. This strategy was seen as a way to circumvent or ameliorate the ways the diasporic client might be negatively categorized as an outsider, especially in terms of his or her language use. Yet, examining these events in recorded detail indicates that diasporic clients are often bargaining for themselves as competent speakers, but are sometimes not able to skillfully bargain politely. In these moments, proxy bargainers intervene when debate and tension increases during bargaining and diasporic visitors do not adequately perform politeness – specifically by deploying religious speech – to soften and minimize tension. Analysis of these interactions indicates how diasporic branching of linguistic practice contrasts communicative skills of mobile populations with subtle, place-based competences, and how the mismatch between these can negatively mark diasporic visitors.

COVID-19 Certificates as a New Form of Mobility Control

The global volume of travel has grown steadily for decades and hence the border closures and travel restrictions in response to COVID-19 have created an unforeseen impact on the number of international border crossings. In air traffic alone the data show a striking 75.6% decrease in the number of scheduled international passengers. We might hasten to think that the strict travel restrictions due to the COVID-19 crisis have in principle treated mobile populations equally – for once we have all been banned from travelling. We could even consider the recent initiatives to introduce “vaccination certificates” as a fair and democratic way to reintroduce safe international travelling. In reality, the idea of a COVID-19 certificate is but a new layer in the broader landscape of highly uneven global mobility where travellers’ citizenship and place of origin truly matter. This article discusses some of the major inequalities embedded in the global mobility regime and argues that the idea of the COVID-19 certificate as an equaliser remains completely disconnected from these underlying realities. To conclude, the article discusses problems related to uneven access to digital travel documents, such as the proposed COVID-19 certificate.

Research on the move: exploring WhatsApp as a tool for understanding the intersections between migration, mobility, health and gender in South Africa

Background Reflecting global norms, South Africa is associated with high levels of cross-border and internal population mobility, yet migration-aware health system responses are lacking. Existing literature highlights three methodological challenges limiting the development of evidence-informed responses to migration and health: (1) lack of engagement with the process of migration; (2) exclusion of internal migrants; and (3) lack of methodologies that are able to capture ‘real-time’ data about health needs and healthcare seeking experiences over both time and place. In this paper, we reflect on a four-month pilot project which explored the use of WhatsApp Messenger - a popular mobile phone application used widely in sub-Saharan Africa – and assessed its feasibility as a research tool with migrant and mobile populations in order to inform a larger study that would address these challenges. Method A four-month pilot was undertaken with eleven participants between October 2019 and January 2020. Using Survey Node, an online platform that allows for the automatic administration of surveys through WhatsApp, monthly surveys were administered. The GPS coordinates of participants were also obtained. Recruited through civil society partners in Gauteng, participants were over the age of 18, comfortable engaging in English, and owned WhatsApp compatible cell phones. Enrolment involved an administered survey and training participants in the study protocol. Participants received reimbursement for their travel costs and monthly cell phone data. Results Out of a possible eighty eight survey and location responses, sixty one were received. In general, participants responded consistently to the monthly surveys and shared their location when prompted. Survey Node proved an efficient and effective way to administer surveys through WhatsApp. Location sharing via WhatsApp proved cumbersome and led to the development of a secure platform through which participants could share their location. Ethical concerns about data sharing over WhatsApp were addressed. Conclusions The success of the pilot indicates that WhatsApp can be used as a tool for data collection with migrant and mobile populations, and has informed the finalisation of the main study. Key lessons learnt included the importance of research design and processes for participant enrolment, and ensuring that the ethical concerns associated with WhatsApp are addressed.

Plasmodium falciparum phenotypic and genotypic resistance profile during the emergence of Piperaquine resistance in Northeastern Thailand

Malaria remains a public health problem in Thailand, especially along its borders where highly mobile populations can contribute to persistent transmission. This study aimed to determine resistant genotypes and phenotypes of 112 Plasmodium falciparum isolates from patients along the Thai-Cambodia border during 2013–2015. The majority of parasites harbored a pfmdr1-Y184F mutation. A single pfmdr1 copy number had CVIET haplotype of amino acids 72–76 of pfcrt and no pfcytb mutations. All isolates had a single pfk13 point mutation (R539T, R539I, or C580Y), and increased % survival in the ring-stage survival assay (except for R539I). Multiple copies of pfpm2 and pfcrt-F145I were detected in 2014 (12.8%) and increased to 30.4% in 2015. Parasites containing either multiple pfpm2 copies with and without pfcrt-F145I or a single pfpm2 copy with pfcrt-F145I exhibited elevated IC90 values of piperaquine. Collectively, the emergence of these resistance patterns in Thailand near Cambodia border mirrored the reports of dihydroartemisinin-piperaquine treatment failures in the adjacent province of Cambodia, Oddar Meanchey, suggesting a migration of parasites across the border. As malaria elimination efforts ramp up in Southeast Asia, host nations militaries and other groups in border regions need to coordinate the proposed interventions.

A multilevel investigation supported by multivariate analysis for tomato product formulation

Industrial processing of tomato includes its cutting and mincing, thermal treatments, and the addition of ingredients, which might induce changes in physicochemical properties of the final products. In this frame, the impact of texturing/thickening [xanthan gum (X) or potato fiber (F)] on the macroscopic, mesoscopic and molecular properties of tomato double concentrate (TDC) was investigated to determine if F can efficiently substitute X, in association with small solutes (sugar and salt) and thermal treatment (cold and hot). At a macroscopic level, multivariate statistics (MANOVA) underlined that color change (ΔE) was increased by X and F addition contrary to heating and the addition of salt and sugar. MANOVA revealed that texture was greatly enhanced through the use of F over X. 1H NMR molecular mobility changes were more controlled by texturing agents (F and X) than thermal treatment and small solutes. Particularly F increased the more rigid population indicating stronger interaction with water molecules resulting in shear-thinning flow. However, adding X contributed into the increase of the dynamic and mobile populations. Therefore, F can be a valid “clean label” substitute of X in modulating tomato products properties.

Surveillance of Human Guinea Worm in Chad, 2010–2018

The total number of Guinea worm cases has been reduced by 99.9% since the mid-1980s when the eradication campaign began. Today, the greatest number of cases is reported from Chad. In this report, we use surveillance data collected by the Chad Guinea Worm Eradication Program to describe trends in human epidemiology. In total, 114 human cases were reported during the years 2010–2018, with highest rates of containment (i.e., water contamination prevented) in the years 2013, 2014, 2016, and 2017 (P < 0.0001). Approximately half of case-patients were female, and 65.8% of case-patients were aged 30 years or younger (mean: 26.4 years). About 34.2% of case-patients were farmers. Cases were distributed across many ethnicities, with a plurality of individuals being of the Sara Kaba ethnicity (21.3%). Most cases occurred between the end of June and the end of August and were clustered in the Chari Baguirmi (35.9%) and Moyen Chari regions (30.1%). Cases in the northern Chari River area peaked in April and in August, with no clear pattern in the southern Chari River area. History of travel within Chad was reported in 7.0% of cases, and male subjects (12.5%) were more likely than female subjects (1.7%) to have reported a history of travel (P = 0.03). Our findings confirm that human Guinea worm is geographically disperse and rare. Although the proportion of case-patients with travel history is relatively small, this finding highlights an additional challenge of surveillance in mobile populations in the final stages of the global eradication campaign.

New chronostratigraphic records of the early-to-middle Holocene in the north-central region of Chile indicate Andean foothills housed hunter-gatherers during pulses of extreme aridity

The scarcity of middle Holocene radiocarbon dates in different regions of the Andes has been interpreted as an indicator of discontinuity in human occupations in response to adverse environmental conditions due to marked aridity. In the subtropical Andes of north-central Chile and adjacent areas, this paucity has been detected in radiocarbon ages between 8000 and 6000 cal BP. A systematic programme of cave excavations with detailed chronologies in the Combarbalá area in the Andean western foothills at 31°S allows questioning the role these spaces and ecosystems played for hunter-gatherers throughout the Holocene. The elusive record of dateable material has been addressed by excavating deposits under rock-shelters which tend to trap sedimentary material. This dataset has been compared with the available climate records and shows a collation between the onset of various site chronologies during the early-to-middle Holocene and periods of extreme aridity. The organization of mobility and the role of Andean foothills for hunter-gatherer settlements is reviewed. Resource availability in the area, namely fresh water supply, good-quality toolstones, faunal resources, and shelters, attracted mobile populations to these environments as indicated by our records as well as others in the broader region.

Maritime Coastal and Island Societies of Australia and New Guinea

Coasts, islands, and marine resources played a central role in the dispersal of people into and across Sahul (the combined landmass of New Guinea and Australia). This vast area spans tropical and temperate latitudes, with changes in the abundance and distribution of coastal resources having greatly influenced how people used these landscapes. Little is known of early coastal and island occupation in the millennia after colonisation because sites of this antiquity are now under water, and most islands formed in the Holocene following the postglacial rise in sea level. Current evidence indicates that small, mobile populations harvested nearshore shellfish and fish by 44–42 ka, with long-distance sea voyaging and interisland trade apparent by 25–20 ka. Increasingly intensive coast and island use is evident by the Mid-Holocene, with specialised maritime economies emerging in tropical latitudes throughout the Late Holocene. Although large gaps remain in our understanding of coastally oriented lifeways, multidisciplinary studies are increasingly challenging global paradigms about the antiquity and importance of marine resources on human cultural development.