Microencapsulated Aromatic Polyetheretherketones and Copolyetheretherketones for 3D-Printing

The presented work presents the results of the studies carried out to elucidate the possibility of obtaining by the microencapsulation method of powdered polyetheretherketones and spherical copolyetheretherketones recommended for use in 3D-printing. The influence of temperature-time and concentration parameters, the reaction medium on the size of microencapsulated particles of polyetheretherketones and copolyetheretherketones was determined. It was determined that the bulk density of microencapsulated particles of polyetheretherketone and copolyetheretherketones is 8-10 times higher than similar unencapsulated ones.

Microencapsulation of Jeringau Rhizome essential oils (Acorus calamus L.) using β-Cyclodextrin

Background: The way to improve the stability of jeringau rhizome essential oils is microencapsulation using β-cyclodextrin. Objective: To determine the efficiency of coating the jeringau rhizome essential oil with β-cyclodextrin and examine its thermostability. Method: The microencapsulation method used was freeze-drying with a ratio of 1:20 and 1:30. Results: The microcapsule efficiency at the ratio of 1:20 and 1:30 was 81.67% and 60.70%, respectively. The thermostability test results showed that the degradation constant of 1:20 microcapsule at 50oC and ambient temperature was 0.0054 and 0.0029, respectively, with a half-life of 128.33 hours and 238.97 hours. Meanwhile, the degradation constant of 1:30 microcapsule was 0.0182 and 0.0080, with a half-life of 38.07 hours and 86.63 hours. Conclusion: The highest efficiency is in the ratio of 1:20 with a percentage of 81.67%. In the thermostability test, the 1:20 microcapsule was better protected and had a longer half-life than the 1:30 microcapsule.

Insect Repellent of Cellulosic Fabrics (A Review)

Day after day, the risk of contracting diseases caused by mosquitoes increased, so studying how to avoid mosquito bites was of great importance. This is done by using a mosquito repellent directly on the skin or applying it to textiles, which are chemicals or natural substances that affect mosquitoes by inhibiting and repelling them. This material is applied by the microencapsulation method, cyclodextrin applications, emulsion, or direct application method.

Sodium alginate microencapsulation improves the short-term oral bioavailability of cannabidiol when administered with deoxycholic acid

Background Cannabidiol (CBD) confers therapeutic effects in some neurological disorders via modulation of inflammatory, oxidative and cell-signalling pathways. However, CBD is lipophilic and highly photooxidative with low oral bioavailability in plasma and brain. In this study, we aimed to design and test a CBD microencapsulation method as a drug delivery strategy to improve the absorption of CBD. Additionally, we evaluated the brain uptake of CBD capsules when administered alongside capsules containing a permeation-modifying bile acid, deoxycholic acid (DCA). Methods Microcapsules containing either CBD or DCA were formed using the ionic gelation method with 1.5% sodium alginate formulations and 100 mM calcium chloride. C57BL/6J wild type mice randomly assigned to three treatment groups (3–4 mice per group) were administered CBD in the following preparations: 1) CBD capsules, 2) CBD capsules + DCA capsules and 3) naked CBD oil (control). To assess the short-term bioavailability of CBD, plasma and brain samples were collected at 0.3, 1 and 3 hours post administration and CBD levels were analysed with liquid chromatography mass spectrometer. Results We produced spherical capsules at 400 ± 50 μm in size. The CBD capsules were calculated to have a drug loading of 2% and an encapsulation efficiency of 23%. Mice that received CBD capsules + DCA capsules showed a 40% and 47% increase in CBD plasma concentration compared to mice on CBD capsules and naked CBD oil, respectively. Furthermore, the CBD capsules + DCA capsules group showed a 48% and 25% increase in CBD brain concentration compared to mice on CBD capsules and naked CBD oil, respectively. In mice treated with CBD capsules + DCA capsules, the brain CBD concentration peaked at 0.3 hours with a 300% increased availability compared to CBD capsules and naked CBD oil groups, which peaked at 1 hour after administration. Conclusions The microencapsulation method combined with a permeation enhancer, DCA increased the short-term bioavailability of CBD in plasma and brain.

A Microencapsulation Method for Delivering Tetrodotoxin to Bivalves to Investigate Uptake and Accumulation

Most marine biotoxins are produced by microalgae. The neurotoxin tetrodotoxin (TTX) has been reported in many seafood species worldwide but its source is unknown, making accumulation and depuration studies in shellfish difficult. Tetrodotoxin is a water-soluble toxin and cannot be directly ingested by shellfish. In the present study, a method was developed which involved binding TTX to solid particles of humic acid and encapsulating them in agar-gelatin capsules. A controlled quantity of TTX-containing microcapsules (size range 20–280 μm) was fed to Paphies australis, a bivalve known to accumulate TTX in the wild. The TTX-containing microcapsules were fed to P. australis every second day for 13 days. Ten P. australis (including five controls fed non-toxic microalgae) were harvested after 7 days and ten after 13 days. Paphies australis accumulated TTX, reaching concentrations of up to 103 µg kg−1 by day 13, exceeding the European Food Safety Authority recommended concentration of 44 μg kg−1 in shellfish. This novel method will allow future studies to explore the effects, accumulation and depuration rates of TTX in different animals and document how it is transferred through food webs.

Development of Microencapsulation Method of Gamma-Decalactone

Microencapsulation is a technique that is increasingly used to encapsulate fragrances. It offers a valuable method to protect aromas against degradation in technological processes and during storage, which extends the usefulness of the aroma in the production and processing of food products. The aim of this research was to develop a microencapsulation method of gamma-decalactone, a cyclic ester with the scent of peach, which is used as a food additive. The carrier used for microencapsulation was an emulsion consisting of rapeseed oil, maltodextrin and gum Arabic. In this work, optimization of the carrier composition was performed in order to obtain a stable emulsion. The effect of inlet air temperature (80 °C, 180 °C) during spray drying on the powder quality parameters was then analyzed. In the final stage, the gamma-decalactone content in the obtained powders was evaluated. The results showed that emulsions based on colza oil and gum Arabic are a good carrier for the microencapsulation of gamma-decalactone. The use of high pressure during homogenization results in better fragmentation and homogenization of the emulsion. Drying at a higher inlet air temperature (180 °C) contributes to a more efficient microencapsulation process in that more aroma is encapsulated inside the capsules with less adhering to their surface.

KAJIAN PUSTAKA FORMULASI DAN EVALUASI MIKROKAPSUL SALUT ENTERIK MENGGUNAKAN ACRYL-EZE® & SURETERIC DENGAN METODE PENGGABUNGAN MIKROENKAPSULASI DENGAN EKSTRUSI-SFERONISASI

Microcapsules were prepared by means of microencapsulation modified by the extrusion-spheronization method. The extrusion-spheronization method is used to cover the shortcomings of the microencapsulation method. The results showed that Acryl-eze and Sureterik can be used in coatings in producing microcapsules. The results of research evaluating the formulation of enteric acetosal coated microcapsules have not resulted in delayed release system that is in accordance with monographic requirements and dissolution profile testing has not shown the elimination stage. The results of the evaluation of the delayed release release system enteric coated microcapsule formulation met the requirements of monograph and dissolution profile test results, except for F3 in buffering conditions. The purpose of this literature review is to examine the enteric-coated microcapsule formulation using Acryl-eze® & Sureteric by combining microencapsulation and spheronization extrusion methods.

Improved Maleic Anhydride Grafting to Linear Low Density Polyethylene by Microencapsulation Method

A common graft copolymerization method usually results in a low degree of grafting due to its poor inter-component interactions. A monomer microencapsulation method should be useful to enhance the current graft copolymerization technique. The maleic anhydride (MAH) grafted with linear low-density polyethylene (LLDPE) was successfully synthesized by monomer microencapsulation without using a direct method in order to find a high degree of grafting. The results showed that the degree of grafting of the LLDPE synthesized by microencapsulation (5.9%) was higher than that achieved with the direct method (5.0%).

Micro Particles: A Review of Recent Developments, Microencapsulation Method, and Therapeutic Strategies

A targeted drug delivery system has a great impact on patience health minimizing the side effect and enhancing therapeutic outcomes, so modern research come towards particulate drug delivery system. Microparticle and nanoparticle are key tools for targeted sustained, delayed, and tissue-specific drug delivery. In this review article, I will discuss microparticle drug delivery system, types of microparticles how drug release from microparticulate system, Materials required for microparticulate drug delivery system, polymers used for micro particles drug delivery system, and procedures employed for the formulation of microparticulate drug delivery systems, Microencapsulation method, and treatment plan depend on Polymeric Microparticles.