The work of an instructional designer is highly dependent on an instructional technology substrate, at every phase of the instructional design work: research, planning, communication and coordination, prototyping, design, content searches, content development, branding, alpha and beta testing, revisions, the delivery of course contents, and the archival in learning object repositories. Technologies in this substrate are built to a variety of standards. There are standards for interoperability, for machines to communicate with each other, for information to be held securely (information assurance), for from-life information to be captured and recorded (whether light, detail, sound, or motion), for communications to be exchanged among people, and for digital artifacts to be labeled and protected and delivered to users. The instructional designer “use case” then refers to the on-ground realities of instructional design work and the critical reliance on instructional technologies, and what this in vivo perspective shows about the need for (in part) user-based insights for instructional technology research, design, and development. Every technology has multiple use cases, or theoretical situations in which users use that technology. An instructional designer use case shows the many uses of technologies by an instructional designer, to shed light on how the software technologies may be better tailored to the needs of instructional designers and other digital content developer stakeholders.