The Medicinal and Poisonous Plants of Southern Africa: Being an Account of Their Medicinal Uses, Chemical Composition, Pharmacological Effects and Toxicology in Man and Animal.

JAMA ◽  
1933 ◽  
Vol 101 (13) ◽  
pp. 1025
2018 ◽  
Vol 64 (01) ◽  
pp. 3-9
Author(s):  
Andzela Brajanovska ◽  
Biljana Bauer

Helleborus sp. are healing plants from the family Ranunculaceae. The aim of this paper is to consider ethnopharmacology and the toxicity of the hellebores which is focused on a detailed research of the value of phytochemicals, as pharmacological attributes of phytomedicine herbs. The data is based on active components. Also, this paper presents the chemical composition of the root in the overall effect of the drug, as well as the importance of the hellebores in pharmacy. It shows a wide range of pharmacological effects such as cardiotonic, immunostimulative, antibacterial, antitumor, diuretic, and emetic. Helleborus odorus Waldst. et Kit. is rich with secondary metabolites such as bufadenolides, flavonoids, phenolic heterozids. With this research it was concluded that these plants have great significance and great application in the formulation of pharmaceutical dosage forms. Keywords: Helleborus sp., phytomedicine, folk medicinal uses, cardiotonic, toxicity, hellebore


2018 ◽  
Vol 2018 ◽  
pp. 1-13 ◽  
Author(s):  
Michael Buenor Adinortey ◽  
Justice Kwabena Sarfo ◽  
Jeffery Kwarteng ◽  
Cynthia Ayefoumi Adinortey ◽  
William Ekloh ◽  
...  

Launaea taraxacifolia (Willd.) Amin ex C. Jeffrey is a herb found mostly in tropical Africa. The plant, commonly found in West Africa, is used in the management of many diseases including cardiovascular, respiratory, haematological, endocrine, and metabolic diseases in Ghana, Nigeria, Benin, Serra Leone, and Senegal. This piece provides comprehensive and updated information on the traditional uses, phytochemical constituents, and pharmacological and toxicological information available on Launaea taraxacifolia to support its medicinal uses and also unearth knowledge gaps for future studies. An electronic literature search using search engines, namely, Google Scholar, ScienceDirect, and PubMed, was carried out to obtain information on the plant. Both common and scientific names of the plant were used as keywords for the search process. This paper captured information on Launaea taraxacifolia from 1985 to 2018. The search revealed that the leaves of the plant possess nutritional/pharmacological effects on diseases such as diabetes mellitus, hypertension, cancer, malaria, bacterial infections, and arthritis. The leaf has been shown to be a rich source of phytoconstituents such as flavonoids, phenolic acids, tannins, alkaloids, glycosides, coumarins, triterpenoids, ascorbic acid, lycopene, and β-carotene. Also, isolated phytoconstituents as well as the safety profile of the plant have been documented. This review on Launaea taraxacifolia has provided a one-stop documentation of information in support of the several purported ethnopharmacological uses of the plant. It also reveals information gaps such as the need to research into its pharmacokinetics, interactions with drugs of importance, and its development into a plant-based drug in order to expand its clinical use.


2010 ◽  
pp. 1361-1371
Author(s):  
Hans Persson

Many plants contain toxic substances heterogeneous in their chemical composition and diverse in their toxic effects. When classifying plant poisonings, a pragmatic approach is to look at the main clinical effects, but it should be emphasized that few plant toxins produce just one type of symptom, and symptomatology is often multiple, although some features predominate....


2006 ◽  
Vol 1 (7) ◽  
pp. 1934578X0600100 ◽  
Author(s):  
William N. Setzer

The essential oils of the barks of Croton monteverdensis Huft and C. niveus Jacq. (Euphorbiaceae) from Monteverde, Costa Rica, were isolated by hydrodistillation in yields of 0.03% and 0.10%, respectively. The chemical composition of the oils was determined by GC–MS. The most abundant essential oil components of C. monteverdensis were α-pinene (17.1%), β-pinene (10.5%), and linalool (8.3%), while C. niveus bark oil was made up largely of α-pinene (14.4%), 1,8-cineole (11.6%), and borneol (8.5%). The major components account for the fragrances and are consistent with the traditional medicinal uses of these plants.


Plants ◽  
2019 ◽  
Vol 8 (7) ◽  
pp. 193
Author(s):  
Blanco-Salas ◽  
Vazquez ◽  
Hortigón-Vinagre ◽  
Ruiz-Tellez

Plants from the genus Mercurialis have a long history of use as herbal remedies in traditional Spanish medicine. The growing interest in the conservation of knowledge related to biodiversity has encouraged us to review the bioactive phytochemicals from the four most widespread Mercurialis species in the Iberian Peninsula (M. annua L., M. ambigua L., M. perennis L., and M. tomentosa L.). First, the medicinal uses of these four species throughout Spain were compiled, and then a bibliographical search on their chemical composition was conducted in an attempt to justify their reported traditional uses. We found that most of the medicinal uses of Mercurialis spp. are supported by scientific evidence. This includes its antidiabetic and antihypertensive properties attributable to the flavonoid rutin and narcissin, respectively; its benefits in the treatment of skin dark spots, attributable to mequinol; and its anti-inflammatory activity, attributable to scopoletin, kaempferol, squalene, and cycloartenol. This review contributes to the validation of the medicinal uses of Mercurialis spp. in Spain and provides some new avenues for further investigations on the biological activity of this interesting medicinal plant.


2006 ◽  
Vol 1 (8) ◽  
pp. 1934578X0600100
Author(s):  
Hesham R. El-Seedi

The essential oil obtained by steam distillation from the leaves and twigs of Eupatorium glutinosum Lam. (Asteraceae) showed antimicrobial activities against a Gram-positive bacterium, three Gram–negative bacteria and three fungi. The results from this study support the vernacular medicinal uses of the plant in folkloric medicine. The chemical composition of the essential oil was analysed by GC and GC-MS, resulting in the identification of 24 constituents accounting for 92.6% of the total mass. The major active component, carvacrol, was isolated using MPLC and characterized by NMR and MS analysis. β-Glucosidase-treatment of the aqueous plant residue yielded a volatile fraction that did not show antimicrobial activitiy, in which the major components were octen-3-ol and (Z)-hex-2-en-1-ol. The essential oil from the species is reported for the first time.


Clay Minerals ◽  
2014 ◽  
Vol 49 (5) ◽  
pp. 717-733 ◽  
Author(s):  
M. Setti ◽  
A. Lόpez-Galindo ◽  
M. Padoan ◽  
E. Garzanti

AbstractThe composition, morphology and crystal order of clay minerals in silt-sized sediments carried in suspensions from 25 major rivers across tropical southern Africa have been studied by X-ray diffractometry and scanning and transmission electron microscopy. Our goal was to determine the spatial variability of clay-mineral associations in diverse geological settings, and in climatic conditions ranging from humid Angola and Zambia to hyperarid Namibia and the Kalahari. Specific attention was paid to the micromorphology and chemical composition of smectite particles. The relative abundance of smectites, illite/mica, kaolinite and chlorite enabled identification of regions characterized by different physical and chemical processes: (1) negligible chemical weathering is documented in Namibia, where river muds mostly contain illite/mica or smectite derived from Damara metasedimentary or Etendeka volcanic rocks; (2) kaolinite documenting intense weathering, reaches a maximum in the Okavango, Kwando and Upper Zambezi, sourced in subequatorial Angola and Zambia; (3) suspended-load muds in the Limpopo and middle Zambezi catchments display intermediate features, with varied assemblages and smectite compositions reflecting diverse parent lithologies. Clay mineralogy and chemical composition are confirmed as a most effective tool to unravel present and past climatic conditions on a continental scale.


1981 ◽  
Vol 09 (03) ◽  
pp. 197-204 ◽  
Author(s):  
I. I. Brekhman ◽  
M. A. Grinevitch

The materials presented here were obtained through a computerized study of 158 Chinese, 204 Korean and 196 Japanese traditional prescriptions with complex and multicomponent characteristics. Oriental medicine strives to complicate sets of prescriptions by using complex recipes and duplicating agents possessing identical effects. The absence of intolerability and side effects of these prescriptions may be given to account for their complexity far closer to the information contents of living bodies than modern scientific medicines which frequently apply substances synthesized or extracted from plants in pure form. Oriental remedial therapy is founded on the use of natural medicines of plant-, animal-, and mineral origin in the form of relatively large amounts of non-treated multi-component mixtures with a preferentially general effect on the organism. It involves the use of the underground parts of plants, aqueous extracts or ground medicinal raw materials. The absence of intensely active and poisonous plants and the scarcity of alkaloid-bearing plants explain the use of remedial mixtures in relatively large doses. Agents possessing antitoxic, anti-inflammatory and especially toning effects are most frequently used. Toning herbs should be given increased attention. A synthesis of traditional medicine and contemporary science on chemical composition and action of remedial plants and animals, and also on the effects that arise with applying complex prescriptions is essentially needed.


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